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Yahoo
20-05-2025
- Business
- Yahoo
Lupus Research Alliance Spearheads Groundbreaking Lupus Nexus Foundational Analyses to Accelerate Personalized Lupus Treatments and a Cure
Largest private funder of lupus research initiates major efforts to integrate numerous biospecimen analyses with clinical data and patient-reported outcomes to accelerate lupus research NEW YORK, May 20, 2025 /PRNewswire/ -- The Lupus Research Alliance (LRA) today announced the launch of the Lupus Nexus Foundational Analyses, a major scientific initiative aimed at creating one of the most comprehensive and accessible lupus research datasets ever assembled. This effort will generate numerous molecular datasets using biospecimens collected through the Lupus Landmark Study, a key component of the Lupus Nexus. These molecular datasets, integrated with robust clinical data, including both clinician- and patient-reported outcomes, represent a first for a private nonprofit in the lupus research space. Lupus is a complex, chronic autoimmune disease that affects multiple organs and presents differently in each individual. Despite decades of research, major gaps remain in understanding the heterogeneity of lupus, which has limited the development of personalized treatments. To help address these gaps, the LRA launched the Lupus Nexus in 2023, a unique registry, biorepository, and information exchange platform called the DREAM (Data Repository, Exchange and Analytics platforM) to catalyze research and accelerate precision medicine in lupus. The Foundational Analyses comprise the next major milestone in the Lupus Nexus program and are being conducted in collaboration with Azenta, Cmbio (formerly known as CosmosID), iRepertoire, LabCorp, MitogenDx/University of Calgary, Sano Genetics, and Standard BioTools. While individual analyses such as whole genome sequencing, RNA sequencing, proteomics, and microbiome profiling are well-established, the Lupus Nexus Foundational Analyses are notable for the integration of multiple high-impact, scientific data types with detailed clinician- and patient-reported outcomes. "The Foundational Analyses are a bold investment in the future of lupus research and a major milestone for the Lupus Nexus," said Devon Kelly, Director of the Lupus Nexus at the LRA. "By pairing molecular analyses with clinical context, we're giving scientists the tools they need to generate new hypotheses and ultimately drive meaningful breakthroughs for people living with lupus." The Foundational Analyses datasets will provide another layer of depth and value to the Lupus Nexus and will begin to be available through the DREAM by the end of 2025 with additional data releases in subsequent years. Researchers will have access to all raw data, those generated by the Foundational Analyses, as well as other data generated from the use of Lupus Nexus biospecimens to support custom studies and foster new discoveries. "The Lupus Nexus represents a transformative shift in how we approach both lupus research and care," said Virginia Pascual, M.D., Gale and Ira Drukier Director of Children's Health Research and Professor of Pediatrics, Weill Cornell Medical College. "Now, with the addition of Foundational Analyses, researchers will, for the first time, have access to molecular data integrated with real-world data. This will help us understand why lupus presents so differently from one patient to the next, and how we can begin to tailor treatments to individuals." Initial data from the Lupus Nexus will be presented at the 16th International Congress on Systemic Lupus Erythematosus (LUPUS 2025) in Toronto on May 20, 2025 (abstract #PV153). For more information about the Lupus Nexus, visit About LupusLupus is a chronic, complex autoimmune disease that affects millions of people worldwide. The immune system, which normally protects against infection, produces autoantibodies that mistakenly target the body's own tissues—leading to damage in the kidneys, brain, heart, lungs, skin, blood, and joints. Lupus disproportionately affects women (90%), typically between ages 15 and 45, and has a higher prevalence and severity among Black, Latinx, Indigenous, Asian, and Pacific Islander populations. About the Lupus Research AllianceThe Lupus Research Alliance is the world's largest non-governmental, nonprofit funder of lupus research. The organization aims to transform treatment by funding the most innovative science, supporting research talent, and advancing discovery toward better diagnostics, improved treatments, and ultimately, a cure. Because all administrative and fundraising costs are covered by the Board of Directors, 100% of all donations go directly to support lupus research programs. To learn more or donate, visit and follow us on X, Facebook, LinkedIn, and Instagram. Rebekah BarnesLupus Research AllianceRBarnes@ View original content to download multimedia: SOURCE Lupus Research Alliance Sign in to access your portfolio
Al Etihad
19-05-2025
- Business
- Al Etihad
National Media Office, Presight join forces to optimise UAE's media ecosystem using applied AI
19 May 2025 17:10 ABU DHABI (ALETIHAD)The National Media Office (NMO) has announced a contract award for a strategic project with Presight, the UAE's leading global big data analytics company powered by AI, to deploy artificial intelligence in support of narrative integrity, information governance and the UAE national media at Make it in the Emirates 2025, the partnership is aligned with the NMO's mandate to grow the UAE's media ecosystem in support of national interests, empower a skilled generation to lead the country's media industry, as well as strengthen regional and international standing. This partnership taps into Presight's expertise in sovereign, generative AI capabilities to give the UAE a strategic edge in media situational awareness and insight-driven content part of the initiative, Presight's AI platform for the NMO will deliver real-time sentiment intelligence across billions of media data points daily, helping secure the UAE's media ecosystem and align media messaging with national a world of fast-paced, complex media dynamics, the UAE is seizing the opportunity to lead with innovation. This initiative centres on optimising media ecosystems for national prosperity, enabling the NMO to consolidate its strategic vision, streamline coordination among media institutions, and amplify narratives aligned with national priorities – all through embracing cutting-edge AI first workstream, AI-Driven Media Insights, will use AI to analyse sentiment, extract key narratives, and recommend evidence-based messaging frameworks for national use. The second, a Data Lake for Strategic Advantage, will consolidate UAE media assets and analytical insights into a unified data hub - supporting secure collaboration across the entire UAE media and government ecosystem in a previously unparalleled custom-built AI solutions for the NMO, developed in the UAE for the UAE, will have the potential for real quantified economic benefits from efficiency gains in manual work hours and automation. Other Presight AI solutions deployed elsewhere in the Emirates are estimated to have achieved over Dh1 billion in annual efficiency gains, more than two million labour-hours saved, and 100% automated data processing - delivering measurable outcomes in line with the UAE's Industrial Strategy and Vision Jamal Mohammed Obaid Al Kaabi, Director-General of the National Media Office, affirmed that the Data Repository project is one of the key instruments supporting NMO's vision of a more intelligent, data-driven and interconnected media landscape. He emphasised that the project goes beyond mere data collection, representing a transformative shift in how media is managed, analysed and understood.'The Data Repository provides an advanced infrastructure that enables the integration of various media data sources and their analysis through AI, generating comprehensive insights that underpin strategic planning and contribute to a unified national narrative,' Al Kaabi further stated, 'The platform also enables anticipation and proactive engagement with future trends and issues, further reinforcing the UAE's leadership in adopting AI to serve the national media agenda.'Dr. Al Kaabi highlighted that the project will reshape the media work environment by automating processes and providing intelligent analytical tools that enhance productivity, reduce inefficiencies and increase operational effectiveness. The system will support institutional coordination and help produce more consistent and impactful content that reflects the country's priorities while reaching both local and global audiences with the highest standards of professionalism and Pramotedham, CEO of Presight, said, 'Our mission at Presight is to turn data into insight, and insight into national impact. This collaboration with the National Media Office is a powerful demonstration of how Applied AI, developed and deployed here in the UAE, can serve as a cornerstone for national we're building an intelligence-driven media ecosystem that not only enhances media situational awareness and strategic coordination, but also ensures that the UAE's national narrative is secured, coherent, credible, and globally resonant. "This initiative is a blueprint for how sovereign AI can be leveraged to reinforce institutional alignment, empower content leadership, and ultimately drive national prosperity through smarter, more unified media engagement.'
