Latest news with #EmilyOliver
Business Wire
7 days ago
- Business
- Business Wire
Gore Launches 0.5 mL Silicone-Free GORE® IMPROJECT® Plunger for Ophthalmic Pre-Filled Syringes
NEWARK, Del.--(BUSINESS WIRE)--W. L. Gore & Associates, Inc. ('Gore'), a global materials science company, recently announced the commercial launch of the 0.5 mL silicone-free* GORE® IMPROJECT® Syringe Plunger within its PharmBIO business. The new offering is specially designed for prefilled syringes used in various applications, including ophthalmic intravitreal injections, and complements the GORE IMPROJECT 1 mLL plunger which Gore launched in mid-2018. Gore's 0.5mL plunger, in combination with a silicone-free glass or advanced polymer syringe barrel, enables pharmaceutical companies to achieve what they've been asking for. To reduce risk associated with silicone by enabling its removal from the syringe. Share Conventional pre-filled syringe systems use silicone to provide a seal and act as a lubricant between the barrel and the plunger. However, peer reviewed literature highlights various problems with silicone including elevated subvisible particulate levels, silicone accumulation in the eye resulting in floaters, silicone-induced protein aggregation resulting in immunological responses, and ocular inflammation and increased intraocular pressure (IOP). In addition, silicone-containing syringes have been associated with particle count increases and fatty acid creation over time. The new plunger enabled syringe systems to achieve particulate levels below the limits of the USP<789> subvisible particle standard in testing performed. The plunger is capable of being terminally sterilized and has been shown to provide suitable break loose and glide force (BL/GF) and CCI performance when used in combination with appropriate syringe components and commercial fill and finish processes. 'Gore's 0.5mL plunger, in combination with a silicone-free glass or advanced polymer syringe barrel, enables pharmaceutical companies to achieve what they've been asking for. To reduce risk associated with silicone by enabling its removal from the syringe plunger and barrel,' emphasized Gore Syringe Business Leader, Emily Oliver. To develop this new product Gore worked closely not only with pharma companies, but also CMOs, terminal sterilization companies, machine companies that design equipment for fill operations, and leading syringe barrel suppliers to bring forth the 0.5 mL silicone-free GORE IMPROJECT Plunger for pre-filled syringes. 'We involved key partners to ensure the product meets the needs of stakeholders throughout the value chain including rigorous fill & finish requirements. This is a breakthrough solution for the industry and was designed with the goal of improving patients' lives,' highlights Russ Hornung, Gore Business Development Manager. The GORE IMPROJECT Plunger may enable today's more challenging ophthalmic injections without the need to introduce silicone oil, cross-linked silicone or resin enhanced silicone. With increasing needs for precise, low-volume injections in ophthalmology, gene therapy, and pediatric care, Gore's 0.5 mL prefilled syringe plunger offers a new alternative. Designed for silicone sensitive applications, this innovation underscores Gore's commitment to enhancing patient outcomes and to driving growth in the evolving injectable therapeutics market. PharmBIO enables life improving therapies of our customers through our leading products and commercial capability. In a highly regulated industry marked by economic pressures and drug development and processing challenges, Gore provides technology-driven products and process components designed for safety, efficiency, reliability and productivity. Gore PharmBIO is focused on satisfying the evolving product, regulatory and quality needs of medical device manufacturers, pharmaceutical and biopharmaceutical customers. The products in the Gore PharmBIO portfolio are tested and manufactured under our stringent quality system. W. L. Gore & Associates is a global materials science company dedicated to transforming industries and improving lives. Since 1958, Gore has solved complex technical challenges in demanding environments — from outer space to the world's highest peaks to the inner workings of the human body. With approximately 13,000 Associates and a strong, team-oriented culture, Gore generates annual revenues of $5 billion.
Yahoo
7 days ago
- Business
- Yahoo
Gore Launches 0.5 mL Silicone-Free GORE® IMPROJECT® Plunger for Ophthalmic Pre-Filled Syringes
NEWARK, Del., June 03, 2025--(BUSINESS WIRE)--W. L. Gore & Associates, Inc. ("Gore"), a global materials science company, recently announced the commercial launch of the 0.5 mL silicone-free* GORE® IMPROJECT® Syringe Plunger within its PharmBIO business. The new offering is specially designed for prefilled syringes used in various applications, including ophthalmic intravitreal injections, and complements the GORE IMPROJECT 1 mLL plunger which Gore launched in mid-2018. Conventional pre-filled syringe systems use silicone to provide a seal and act as a lubricant between the barrel and the plunger. However, peer reviewed literature highlights various problems with silicone including elevated subvisible particulate levels, silicone accumulation in the eye resulting in floaters, silicone-induced protein aggregation resulting in immunological responses, and ocular inflammation and increased intraocular pressure (IOP). In addition, silicone-containing syringes have been associated with particle count increases and fatty acid creation over time. The new plunger enabled syringe systems to achieve particulate levels below the limits of the USP<789> subvisible particle standard in testing performed. The plunger is capable of being terminally sterilized and has been shown to provide suitable break loose and glide force (BL/GF) and CCI performance when used in combination with appropriate syringe components and commercial fill and finish processes. "Gore's 0.5mL plunger, in combination with a silicone-free glass or advanced polymer syringe barrel, enables pharmaceutical companies to achieve what they've been asking for. To reduce risk associated with silicone by enabling its removal from the syringe plunger and barrel," emphasized Gore Syringe Business Leader, Emily Oliver. To develop this new product Gore worked closely not only with pharma companies, but also CMOs, terminal sterilization companies, machine companies that design equipment for fill operations, and leading syringe barrel suppliers to bring forth the 0.5 mL silicone-free GORE IMPROJECT Plunger for pre-filled syringes. "We involved key partners to ensure the product meets the needs of stakeholders throughout the value chain including rigorous fill & finish requirements. This is a breakthrough solution for the industry and was designed with the goal of improving patients' lives," highlights Russ Hornung, Gore Business Development Manager. The GORE IMPROJECT Plunger may enable today's more challenging ophthalmic injections without the need to introduce silicone oil, cross-linked silicone or resin enhanced silicone. With increasing needs for precise, low-volume injections in ophthalmology, gene therapy, and pediatric care, Gore's 0.5 mL prefilled syringe plunger offers a new alternative. Designed for silicone sensitive applications, this innovation underscores Gore's commitment to enhancing patient outcomes and to driving growth in the evolving injectable therapeutics market. PharmBIO enables life improving therapies of our customers through our leading products and commercial capability. In a highly regulated industry marked by economic pressures and drug development and processing challenges, Gore provides technology-driven products and process components designed for safety, efficiency, reliability and productivity. Gore PharmBIO is focused on satisfying the evolving product, regulatory and quality needs of medical device manufacturers, pharmaceutical and biopharmaceutical customers. The products in the Gore PharmBIO portfolio are tested and manufactured under our stringent quality system. About Gore W. L. Gore & Associates is a global materials science company dedicated to transforming industries and improving lives. Since 1958, Gore has solved complex technical challenges in demanding environments — from outer space to the world's highest peaks to the inner workings of the human body. With approximately 13,000 Associates and a strong, team-oriented culture, Gore generates annual revenues of $5 billion. Referenced peer-reviewed literature available upon request.*silicone not intentionally added as a raw material or in the manufacturing process View source version on Contacts Media Contacts W. L. Gore & AssociatesNicole Miller, Gore Communications & External AffairsContact by email W. L. Gore & AssociatesErnesto Sosa, Gore PharmBIO Global Marketing LeaderContact by email Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
CBC
19-02-2025
- General
- CBC
Owner of P.E.I. animal sanctuary hopes to rebuild barn that burned, costing some animals their lives
Emily Oliver and her family rescue abused and neglected animals, often taking in pets that people can no longer care for. After a devastating fire on Feb. 10, the Oliver Ohana Farm in Oyster Bed Bridge is feeling the love from Prince Edward Islanders rushing to help. Nicola MacLeod reports.
CBC
17-02-2025
- General
- CBC
P.E.I. farm owner overwhelmed by community support after barn fire
The owner of a petting farm in rural Prince Edward Island says she is overwhelmed and deeply grateful for the support from the local community one week after a fire destroyed one of the farm's barns. Emily Oliver, who runs the Oliver Ohana Farm in Oyster Bed Bridge, said her family rescues abused and neglected animals, often taking in pets that people can no longer care for. On the evening of Feb. 10, a fire broke out in one of the farm's barns. Some animals died in the blaze. Since then, Oliver said the outpouring of support from neighbours, Islanders and even people from other provinces has been "absolutely outstanding." "People are plowing the lane for us, just because there's so much going on we can't get the snowblower out," Oliver told CBC News. "I still have about hundreds of messages I'm still trying to filter through. I'm from away, but I feel like an Islander these last few days." The farm typically takes in 20 to 30 animals each year, she said. Currently, they have about 40 animals remaining, many of them goats. A previous employee also set up an online fundraising page to help the farm. It has raised nearly $10,000. "I work full time at the Salvation Army, so I'm usually the one that's helping … and then to be on the other side of things and receiving the community support, it's mind-blowing," Oliver said. "The community definitely makes us want to rebuild and take in more animals." Police believe the fire was accidental and caused by an electrical issue, according to an RCMP release. 'Every farmer's worst nightmare' Oliver, who is also a volunteer firefighter, said despite responding to fires in the past, nothing prepared her for what she saw that night. Firefighters took about two hours to extinguish the blaze, but the barn was destroyed in just 20 minutes, she said. Among the animals lost was a stallion, a bull calf, chickens and pigs. "When you go to a fire, you pack up the hoses and you leave. You don't know what happens after. So this is definitely a new experience," she said. "It's every farmer's worst nightmare."
