Latest news with #Gottschalk
Yahoo
28-03-2025
- Yahoo
21-year-old Brandon man arrested after fight, stabbing
SIOUX FALLS, S.D. (KELO) – A 21-year-old Brandon man faces charges of aggravated assault and vehicular battery after a fight sprawled into downtown Sioux Falls early Friday morning. Jewish comedian heckled at Sioux Falls comedy club According to Sioux Falls Police Department spokesman Sam Clemens, Sean Matthew Gottschalk, of Brandon, was arrested shortly after midnight Friday. Gottschalk is accused of stabbing a man in the chest and then hitting another person with his car near the parking ramp along 10th Street. Clemens said Gottschalk called police after he hit two men with his car and was arrested. The man that was stabbed was taken to the hospital but is facing non-life threatening injuries. Clemens said there were a lot of people involved. 'There's some issues between that group of people,' Clemens said. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
Forbes
26-03-2025
- Automotive
- Forbes
Perfect Moment Launches Capsule Collection With BWT Alpine F1 Team
Perfect Moment Launches Capsule Collection With BWT Alpine F1 Team Courtesy of Perfect Moment Fusing motorsport engineering and luxury sportswear, Perfect Moment and BWT Alpine Formula One Team have unveiled today an exclusive capsule skiwear collection that celebrates their shared French alpine heritage while pushing the boundaries of high performance apparel. The limited-edition collection — the first of multiple drops planned under the brands' 3-year partnership — comes at a time when F1 racing events and teams are gaining increasing popularity following the success of Netflix's documentary series, Formula 1: Driving to Survive. Featuring a range of skiwear, base layers, lifestyle pieces as well as accessories, the 20-piece range brings together Alpine F1's racing technology and Perfect Moment's signature ski aesthetic to create a range designed for both extreme conditions and fashion-forward viabilities. 'This collaboration is an exciting milestone for Perfect Moment, blending the energy of BWT Alpine Formula One Team with our signature style and technical excellence,' says Jane Gottschalk, Perfect Moment's co-founder and creative director. 'The French heritage of BWT Alpine Formula One Team and Perfect Moment is a natural fit. For me, it just made sense.' Derived organically from both brands' common roots in the French Alps and mutual pursuits of performance excellence, Gottschalk says Perfect Moment, originally founded by world-leading Freeride champions, and Alpine F1 share 'a relentless pursuit of excellence' in their respective domains. The Perfect Moment x BWT Alpine F1 Team collab collection focuses on performance and style Courtesy of Perfect Moment 'This partnership felt completely natural from the outset,' says Gottschalk, before noting that both racing suits and ski suits are engineered for extreme performance, designed to withstand high speeds and intense conditions while ensuring comfort and protection. 'It's this shared commitment to technical excellence that makes our collaboration so seamless.' A slight departure from Perfect Moment's usual silhouettes marrying elegance with performance confidence, the standout pieces from the collection adopt a notably sportier aesthetic featuring Alpine's bold racing colors and elements of the F1 team's aerodynamic engineering and cutting-edge technology, all completed with advanced fabrics that ensure the skiwear meets rigorous performance standards. Known for its elevated, polished skiwear styles on and off the slopes, the brand's latest collaboration with Alpine F1 reinforces its position as the leading name in performance as well as luxury and style. 'Formula One is the pinnacle of high-performance engineering, and collaborating with a team that operates at such an elite level reinforces our commitment to innovation,' says Gottschalk. Supported by a high-impact campaign showcasing the versatility of the collection, the products under the new range are available exclusively online at complemented by special pop-up experiences at selected race events. The pop-ups, specifically designed for the collaborated collection, are aimed to offer a different and immersive consumer experience compared to traditional retail spaces. 'We want people to step into the Perfect Moment x Alpine world,' Gottschalk shares. 'Fans will have the chance to see, feel, and interact with the collection in an environment that blends the energy of the racetrack with the spirit of mountain life.' The collection of 20 styles, launching today on March 26, includes a range of performance-driven skiwear together with base layers and lifestyle pieces Courtesy of Perfect Moment It's clear Gottschalk has her eyes set on growth. Since the company's listing on NYSE, the brand has orchestrated a series of well-positioned and publicised events and appointments, with the latest news being the AW25 wholesale bookings exceeding USD$12.7m (a 30% increase on 2024's total annual wholesale bookings) and a number of new senior management hires. In addition, Perfect Moment is set to expand further from luxury performance wear and skiwear to broader luxury outerwear, extending the brand's presence beyond the traditional fall/winter season. The collaboration with Alpine F1 leads a growing trend of luxury sportswear brands forming partnerships outside their traditional domains. Gottschalk sees this as responding to evolving customer expectations: 'Customers today expect more from their clothing — it needs to perform seamlessly across multiple environments while making a statement. A collaboration like this demonstrates that high-performance apparel can also be high-fashion.' The collection launches today, with pop-ups planned at two major race events and in London, offering fans and fashion enthusiasts the opportunity to experience what Gottschalk calls 'the perfect fusion of two brands that thrive in extreme environments — whether on the track of in the mountains.'
Yahoo
25-03-2025
- Business
- Yahoo
Foghorn Therapeutics Announces New Preclinical Data for Selective SMARCA2 Inhibitor FHD-909 and Selective CBP and EP300 Degrader Programs at 2025 AACR Meeting
- FHD-909 (LY4050784) advancing in an ongoing Phase 1 trial in SMARCA4 (BRG1) mutated cancers, with non-small cell lung cancer (NSCLC) as the primary target population - Oral presentation on preclinical data for FHD-909 in combination with chemotherapy, pembrolizumab and KRAS inhibitors, in SMARCA4 mutant cancers - Poster presentations on preclinical data for Selective CBP degrader in combination with chemotherapy and targeted agents and for Selective EP300 degrader in hematological malignancies CAMBRIDGE, Mass., March 25, 2025 (GLOBE NEWSWIRE) -- Foghorn® Therapeutics Inc. (Nasdaq: FHTX), a clinical-stage biotechnology company pioneering a new class of medicines that treat serious diseases by correcting abnormal gene expression, today announced that new preclinical combination data for FHD-909, a potential first-in-class selective SMARCA2 inhibitor will be presented as an oral presentation at the 2025 American Association for Cancer Research (AACR) Annual Meeting being held April 25-30, 2025, in Chicago, Illinois. Poster presentations on the Phase 1 trial design for FHD-909 and on preclinical data for the Selective CBP program and the Selective EP300 degrader program will also be presented. 'We are excited to share new preclinical data at this year's AACR conference further strengthening the promise of our differentiated programs,' said Adrian Gottschalk, President, and Chief Executive Officer of Foghorn. 'Importantly, enrollment and dose escalation are on track in the ongoing Phase 1 trial evaluating FHD-909, a first-in-class oral selective SMARCA2 inhibitor, in SMARCA4 mutated cancers with initial focus in NSCLC. New preclinical data on expansion opportunities for FHD-909 in combination with chemotherapy, pembrolizumab and KRAS inhibitors, in SMARCA4 mutant cancers will be featured in an oral presentation. We look forward to continued progress on our FHD-909 program in collaboration with Lilly.' Mr. Gottschalk added, 'Our Selective CBP degrader and Selective EP300 degrader programs have shown highly selective and robust anti-tumor activities, and two poster presentations will highlight preclinical data supporting their advancement towards the clinic. Our pipeline programs continue to show unmatched selectivity for challenging targets, and we are focused on strong execution across our portfolio.' Presentation Details FHD-909 Oral Presentation Title: LY4050784, a selective inhibitor of SMARCA2, demonstrates synergistic activity in combinations with pembrolizumab or KRAS inhibitorsMini Symposium: Experimental and Molecular Therapeutics – Continuum of Innovation: Biological Therapeutic AgentsSession Date/Time: Monday, April 28, 2:30 p.m. – 4:30 p.m. CDTPresenter: Nathan Brooks, Pharmacology Team Leader, Oncology, Eli Lilly And Company Poster Presentation Title: A First-in-human Phase 1 Study of LY4050784, an Oral, Potent, and Selective SMARCA2 Inhibitor, in Patients with Advanced Solid Tumors with SMARCA4 Alterations (Trial in Progress)Session: Phase I Clinical Trials in Progress 1Poster Number: 51/4Session Date/Time: Monday, April 28, 2:00 p.m. – 5:00 p.m. CDTPresenter: Timothy A. Yap, MBBS, PhD, FRCP, Professor of Investigational Cancer Therapeutics, MD Anderson Cancer Center Selective CBP Degrader Poster Presentation Title: Establishing rational combination strategies with selective CBP degraders in solid tumor indicationsSession: Experimental and Molecular Therapeutics – Degraders and Glues 2Poster Number: 18 / 3Session Date/Time: Monday, April 28, 9:00 a.m. – 12:00 p.m. CDTPresenter: Molly M. Wilson, Scientist, Biology, Foghorn Therapeutics Selective EP300 Degrader Poster Title: Anti-cancer activity of potent and selective EP300 degradation in hematological malignanciesSession: Clinical Research – Molecular Genetics and Epigenetics of TumorsPoster Number: 34 / 17Session Date/Time: Wednesday, April 30, 9:00 a.m. – 12:00 p.m. CDTPresenter: Claudia Dominici, Scientist, Biology, Foghorn Therapeutics The presentation and the posters will be accessible under the Science section of the Company's website after the conference. About FHD-909 FHD-909 (LY4050784) is a potent, first-in-class, allosteric and orally available small molecule that selectively inhibits the ATPase activity of SMARCA2 (BRM) over its closely related paralog SMARCA4 (BRG1), two proteins that are the catalytic engines across all forms of the BAF complex, one of the key regulators of the chromatin regulatory system. In preclinical studies, tumors with mutations in SMARCA4 rely on SMARCA2 for BAF function. FHD-909 has shown significant anti-tumor activity across multiple SMARCA4 mutant lung tumor models. About Foghorn Therapeutics Foghorn® Therapeutics is discovering and developing a novel class of medicines targeting genetically determined dependencies within the chromatin regulatory system. Through its proprietary scalable Gene Traffic Control® platform, Foghorn is systematically studying, identifying and validating potential drug targets within the chromatin regulatory system. The Company is developing multiple product candidates in oncology. Visit our website at for more information on the Company, and follow us on X and LinkedIn. Forward-Looking Statements This press release contains 'forward-looking statements.' Forward-looking statements include statements regarding the Company's clinical trials, including the ongoing Phase 1 trial evaluating FHD-909, a first-in-class oral selective SMARCA2 inhibitor, in SMARCA4 mutated cancers, product candidates and research efforts and other statements identified by words such as 'could,' 'may,' 'might,' 'will,' 'likely,' 'anticipates,' 'intends,' 'plans,' 'seeks,' 'believes,' 'estimates,' 'expects,' 'continues,' 'projects' and similar references to future periods. Forward-looking statements are based on our current expectations and assumptions regarding capital market conditions, our business, the economy and other future conditions. Because forward-looking statements relate to the future, by their nature, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict. As a result, actual results may differ materially from those contemplated by the forward-looking statements. Important factors that could cause actual results to differ materially from those in the forward-looking statements include regional, national or global political, economic, business, competitive, market and regulatory conditions, including risks relating to our clinical trials and other factors set forth under the heading 'Risk Factors' in the Company's Annual Report on Form 10-K for the year ended December 31, 2024, as filed with the Securities and Exchange Commission. Any forward-looking statement made in this press release speaks only as of the date on which it is made. Contact: Karin Hellsvik, Foghorn Therapeutics Inc. khellsvik@ in to access your portfolio
Associated Press
26-02-2025
- Business
- Associated Press
Perfect Moment Co-Founder and Chairman Purchases 51,000 Shares of Company Stock in the Open Market
Perfect Moment Ltd. (NYSE American: PMNT), the high-performance, luxury skiwear and lifestyle brand that fuses technical excellence with fashion-led designs, reported that its co-founder and chairman, Max Gottschalk, has increased his ownership in the company through a series of open market purchases. The purchases were reported in a Form 4 filed with the U.S. Security and Exchange Commission (SEC). According to the filing, on February 25, 2025, the chairman acquired 51,000 shares of the company's common stock, bringing his beneficial ownership with co-founder and president, Jane Gottschalk, to approximately 4.1 million shares or 24.3% of the shares outstanding. 'These recent personal purchases reflect my great confidence in the future of Perfect Moment, its new leadership and phenomenal growth potential,' stated Gottschalk. 'I'm especially encouraged by the company's continued expansion from its strong base in luxury performance skiwear into the broader, faster-growing global luxury outerwear market.' This expansion has included the recent introduction of new year-round products across new categories designed to complement the company's current Fall/Winter lineup as well as its anticipated Summer 2025 Collection. These products are expanding the brand's appeal from the slope to the city and extending the selling period to throughout the year. The company has also made a series of strategic moves designed to drive growth and expansion of its brand presence across global markets. It opened seasonal retail stores in New York and London and engaged several new top-tier sales agencies strategically located around the world. The company's new U.S. distribution center has lowered delivery costs, expanded margins and improved customer experience. Most recently, the company appointed new senior leadership who have driven growth for other major luxury brands. It also completed the first phase of a multi-channel global co-marketing campaign in collaboration with Diageo (NYSE:DEO), the $61 billion global leader in beverage alcohol and producer of Johnnie Walker, the world's #1 Scotch Whisky. 'These many positive developments further strengthen my belief in our strategic direction and that we have the right team in place to take the company to the next level,' added Gottschalk. 'As such, I plan to opportunistically make additional open market purchases as conditions permit.' Details of Perfect Moment stock purchases by management are available in the company's filings with the SEC at About Max Gottschalk Gottschalk is a strategic investor and global fund manager who has traded, seeded and invested in multiple companies over the past 25 years. This includes extensive experience in venture capital and private equity, where he has successfully backed, operated and exited a number of ventures, including Faena Group, Everlane, Vita Coco and Good Catch. He also helped lead Perfect Moment's IPO on the NYSE American Stock Exchange in April of last year. Gottschalk is presently the founding partner at Ocean 14 Capital, a private equity fund with a mission of protecting our oceans through strategic investment. He is also a co-founding partner at Vedra Partners, a multi-family office based in London and Switzerland. In 1998, Gottschalk co-founded Gottex Fund Management, a global asset manager which he brought public on the Swiss Stock Exchange in 2007 at a market cap of US$2.2 billion. He currently serves as its EMA CEO. He earlier headed sales for Bear Stearns' fixed income derivatives hedge fund based in New York. He earned his business degree in finance, marketing and international business from the University of Virginia, graduating with honors. He returned to University of Virginia as a visiting professor to teach a course on Impact Investing. About Perfect Moment The Perfect Moment brand was born in 1984 in the mountains of Chamonix, France. The Perfect Moment brand was relaunched by Max and Jane Gottschalk in 2012 and was acquired by the company in 2017 and 2018. Perfect Moment is a high-performance luxury skiwear and lifestyle brand. It blends technical excellence with fashion-forward designs, creating pieces that effortlessly transition from the slopes to the city, the beach, and beyond. Initially the vision of extreme sports filmmaker and professional skier Thierry Donard, the brand was built on a sense of adventure that has sustained for over 20 years. Donard, fueled by his personal experiences, was driven by a desire to create pieces that offered quality, style and performance, pushing the wearer in the pursuit of every athlete's dream: to experience 'The Perfect Moment.' In 2012, British-Swiss entrepreneurial couple Jane and Max Gottschalk took ownership of the brand. Under Jane's creative direction Perfect Moment was injected with a new style focus, one that reignited the spirit of the heritage brand, along with a commitment to improving fit, performance and the use of best-in-class functional materials. As such, the designs evolved into distinct statement pieces synonymous with the brand as we know it today. Today, the brand is available globally, online and at major retailers, including MyTheresa, Net-a-Porter, Harrods, Selfridges, Saks, Bergdorf Goodman and Neiman Marcus. Perfect Moments' global luxury ski apparel market is expected to reach $1.7 billion in 2024 and grow at a compound annual growth rate (CAGR) of 6.2% through 2032, according to Business Research Insights. Its expanding market for luxury outerwear is expected to reach $17.9 billion in 2024 and grow at a 6.7% CAGR through 2032, reports Business Research Insights. Important Cautions Regarding Forward-Looking Statements This press release contains 'forward-looking statements' within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press release may be identified by the use of words such as 'anticipate,' 'believe,' 'contemplate,' 'could,' 'estimate,' 'expect,' 'intend,' 'seek,' 'may,' 'might,' 'plan,' 'potential,' 'predict,' 'project,' 'target,' 'aim,' 'should,' 'will' 'would,' or the negative of these words or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements are neither historical facts nor assurances of future performance. Instead, they are based on our current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate. Our actual results and financial condition may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause our actual results and financial condition to differ from those contained in the forward-looking statements, include those risks and uncertainties described more fully in the section titled 'Risk Factors' in the final prospectus for our initial public offering and in our Form 10-K for the fiscal year ended March 31, 2024, filed with the Securities and Exchange Commission. Any forward-looking statements contained in this press release are made as of this date and are based on information currently available to us. We undertake no duty to update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise. CONTACT: Company Contact Julie Robinson, Brand Director Perfect Moment Tel +44 7595178702 Email contactInvestor Contact Ronald Both or Grant Stude CMA Investor Relations Tel (949) 432-7566 Email contact KEYWORD: UNITED KINGDOM EUROPE SOURCE: Perfect Moment Ltd. Copyright Business Wire 2025. PUB: 02/26/2025 08:31 AM/DISC: 02/26/2025 08:32 AM
