Latest news with #Gurley
Epoch Times
13-05-2025
- Health
- Epoch Times
Cinnamon Supplements May Reduce Effectiveness of Medications, Study Finds
That sprinkle of cinnamon in your coffee or oatmeal? Probably harmless. But taken as a supplement, it could change how your body processes prescription drugs, new research suggests. Cinnamaldehyde, the compound behind cinnamon's signature flavor and scent, can interfere with how the body processes medications. The recent study on human liver and gut cells found that at high concentrations, the compound may speed up drug metabolism, clearing medications before they can take full effect. 'Cinnamaldehyde has a low to moderate potential for drug interactions based upon our preliminary in vitro studies,' co-author of the study Bill Gurley, who is a principal scientist at the National Center for Natural Products Research, told The Epoch Times in an email. What Researchers Discovered In a At concentrations above 270 micrograms per milliliter, which would be reached only through taking high-dose supplements, cinnamaldehyde activated these receptors, acting like gatekeepers, telling the body how quickly to break down and eliminate medications. Researchers say that this could be a concern for people taking certain medications—particularly drugs metabolized by the liver enzymes CYP2C9 and CYP1A2, such as some blood thinners, diabetes drugs, antidepressants, and anti-inflammatory drugs. 'Cinnamon and cinnamon-based supplements are quite safe when used in moderation,' Gurley said. 'The likelihood that cinnamaldehyde poses any risk for clinically relevant drug interactions is quite low.' Related Stories 5/11/2025 11/19/2024 The researchers found no changes in PXR activity at lower levels of cinnamaldehyde (up to 20 micrograms per milliliter), suggesting that everyday use—like those typically used in cooking—is unlikely to be a problem. Even in a 'It is okay to consume cinnamon in food or take it as a supplement in moderation,' Shabana Khan, a principal scientist at the university's National Center for Natural Products Research and co-author of the study, told The Epoch Times in an email. Health concerns, however, can arise when supplements are used in high doses or for long periods—especially without a doctor's knowledge. Some people take 'It's difficult to define how much is too much since different preparations or products / supplements will have different quantities or vary in composition,' she said. 'It should be used in moderation.' Know Your Cinnamon Cinnamon is used in several forms, each with varying levels of risk. Ground cinnamon, the kind you likely have in your spice rack, is used in cooking and baking, and up to a teaspoon is considered safe. Cinnamon oil, often used in foods and personal care products, poses little risk in small amounts. However, supplements, which can contain anywhere from 500 to 1,000 milligrams per dose, can be more concentrated and potentially interfere with medications when taken regularly. Most cinnamon sold in U.S. stores is Labels don't always list the type of cinnamon used; unless otherwise stated, it's mostly like going to be cassia. You can also contact the manufacturer for clarification, especially if you are taking cinnamon in supplement form. Apart from cinnamaldehyde, cinnamon also contains coumarin, a naturally occurring blood thinner. 'Cassia cinnamon, often sourced from regions like Southern China, contains significantly higher levels of coumarin and is a potent blood thinner compared to true cinnamon (Cinnamomum verum) from Sri Lanka,' study co-author Amar Chittiboyina, associate director at the National Center for Natural Products Research, told The Epoch Times in an email. True cinnamon or 'We strongly advise individuals currently taking blood thinners who are considering incorporating cinnamon into their daily routine to consult with their primary healthcare physician,' Chittiboyina said. Still, researchers say that when used appropriately, cinnamon may offer benefits. A 2022 scientific But as with many natural compounds, the benefits may depend on the dose, the form, and how it's used. Other Competing Foods and Herbs Cinnamon isn't the only natural ingredient that can interact with medications. Common foods and herbs can affect how drugs are absorbed or broken down—something to keep in mind if you take medication regularly. For example, grapefruit can block like warfarin. Dairy products can reduce the absorption of some antibiotics, making them less effective. Several herbs and supplements have also been linked to well-documented drug interactions, according to Gurley. St. John's Wort, often used for mild depression, can reduce the effectiveness of medications like antidepressants, birth control pills, and antivirals by speeding up liver enzyme activity. Goldenseal may slow down drug metabolism of certain statins, antihistamines, and sedatives, increasing drug levels in the body. And licorice root—unless it's had the glycyrrhizin compound removed—can raise blood pressure and interfere with blood pressure medications. 'Our best advice is to talk to a health care provider before using any supplements along with prescription medicine,' Khan said.
USA Today
01-05-2025
- Sport
- USA Today
Crazy Todd Gurley stat puts into perspective just how outstanding he was with the Rams
Crazy Todd Gurley stat puts into perspective just how outstanding he was with the Rams Todd Gurley is one of the biggest 'what-if' stories of the last 10 years. He came into the NFL as a highly regarded prospect out of Georgia despite tearing his ACL in college and still managed to outperform expectations with the Rams. He won AP Rookie of the Year in 2015 in just 13 games, was named Offensive Player of the Year in 2017 and led the NFL in total touchdowns twice. He was a superstar in St. Louis and Los Angeles, but injuries robbed him of what could've been a Hall of Fame career. This mind-blowing stat shows just how productive he was in his brief time in the NFL. Since 2015, only two players have scored more rushing touchdowns than Gurley, who has 67: Derrick Henry (106) and Ezekiel Elliott (74). Rushing touchdowns since 2015 Derrick Henry: 106 (136 games) Ezekiel Elliott: 74 (135 games) Todd Gurley: 67 (88 games) Henry and Gurley came into the NFL a year later than Gurley but both are still playing. Gurley, on the other hand, hasn't played since 2020, spending the last four years in retirement. And still, he has the third-most rushing touchdowns in the league since 2015. Gurley scored his 67 career touchdowns in 88 games, while Elliott has played 135 games and Henry has played 136. The only player even somewhat close to Gurley's touchdown efficiency since 2015 is Josh Jacobs, who has scored 61 rushing touchdowns in 90 career games. Incredibly, Gurley is still only 30 years old, accomplishing all of his feats by the age of 26. In NFL history, only three running backs scored more touchdowns by the age of 26 than Gurley. Rushing touchdowns by the age of 26 Emmitt Smith: 96 LaDainian Tomlinson: 72 Jim Brown: 70 Todd Gurley: 67 That's the entire list. Gurley was on a Hall of Fame trajectory before his knee issues caused him to retire at a young age, and it's unfortunate we never got to see his prime for more than a few years. Had he been able to sustain the longevity of someone like Derrick Henry or Saquon Barkley, he would've put up massive numbers.
Chicago Tribune
24-04-2025
- Sport
- Chicago Tribune
St. Edward's Sarah Gurley has never tried travel softball in the summer. She plays baseball. ‘Figuring it out.'
St. Edward's Sarah Gurley oughta be in pictures. The sophomore shortstop, in a manner of speaking, is in a league of her own. She burst onto the scene last spring, hitting .521 and earning Chicagoland Christian Conference's player of the year and Illinois Coaches Association third team all-state honors. Impressive, especially when considering this. 'I've never played travel softball,' Gurley said. Say what? 'Sarah is a baseball player,' Green Wave coach Jerry Kublank said. 'She plays baseball in the summer and she likes to catch. She's a good catcher, but I need her at shortstop. 'You've seen some plays she made, showing good instincts to get that force at third base.' It came with the bases loaded and one out in the seventh inning Wednesday in St. Edward's come-from-behind 16-9 conference win over visiting Aurora Christian at the Elgin Sports Complex. Gliding over from the hole between short and third on a hard-hit ball that bounced away from sophomore Layne Dawson, Gurley scooped it up and beat a runner to the bag for a force out. 'She's picked up skills that some other players don't have,' said Kublank, who has coached baseball and softball for more than 50 years. 'Last weekend in the Larkin Tournament, she turned a couple double plays.' Gurley looked even better Wednesday at the plate, leading off the game with a triple to the wall in right field and then driving in three more runs with another triple in a 10-run sixth as the Green Wave (7-7, 4-1) rallied from an 8-6 deficit. In between? Gurley singled, was hit by a pitch and drew a walk while finishing with five runs scored. The strong support helped sophomore Kendall Pemberton gut out a win in the circle. She was filling in for ace Alaina Nolan, who suffered a hand injury Monday that will likely to keep her out of action for up to a week. That's a relief to Kublank, who learned earlier in the day school officials accepted an Illinois High School Association offer to host a regional. 'It just meant we all had to step up a bit to try to fill the spot,' said Gurley, who usually bats third. Freshman outfielder Mady Wagner and junior first baseman Grace Kendall had big days at the plate with three hits apiece for Aurora Christian (2-7, 0-4). Wagner homered and Kendall doubled twice for the young Eagles, who have no seniors on the roster. Gurley, meanwhile, has found a home with St. Edward. 'We're glad she decided to play softball,' Kublank said. 'Matter of fact, when she was a freshman, she was thinking of going out for baseball here. 'She was in our camp and I was thinking, 'Please, no, you have a better future in college in softball.'' Gurley, who is hitting .512 this year, had the lone hit off Newark ace Kodi Rizzo in a 4-0 loss in last season's regional final. She struck out just twice last spring and has not struck out this season. 'I've been playing baseball since I was 5 and didn't start playing softball until starting high school,' said Gurley, the middle of Glen and Jennifer's three children. Her oldest brother, Zach, is a senior. Her youngest brother, Nate, is in seventh grade. 'Baseball has always been a good all-around experience,' Sarah said. 'The guys respected me, I respected them and we get along. 'Nate and I played on the same team that my dad coached for a while.' She also has played two seasons of varsity basketball at St. Edward and continues to play summer rec league baseball. 'I'd like to play one of them in college if opportunities are there,' she said. 'I'm still figuring it out. 'It's always a transition going between baseball and softball, but I adjust. I'm liking softball more, but I think I still like baseball better.' Kublank doesn't mind. 'I don't think summer baseball is hurting her,' he said. 'It's OK with me.'
USA Today
21-04-2025
- Sport
- USA Today
2025 NFL Draft prospect compared to ex-Rams RB Todd Gurley
2025 NFL Draft prospect compared to ex-Rams RB Todd Gurley The Los Angeles Rams have a potential franchise running back in Kyren Williams, but they could still look to add another rusher in the 2025 NFL Draft. And if they want to find someone that emulates one of their old franchise running backs, they could find him in Iowa's Kaleb Johnson. Pro Football Focus compared Johnson to ex-Rams star running back Todd Gurley, per their 2025 Draft guide. "Johnson is a physically gifted running back who excels with the ball in his hands. As an early-down player, he can be successful behind any blocking scheme with good vision, light footwork and impressive burst and power. However, his lack of polish and reliability in third-down situations could keep him from being an every-down running back." Johnson led the Big 12 with 1,537 rushing yards and 21 rushing touchdowns in 2024. He also caught 22 receptions for 188 yards and two touchdowns. At 6-foot and 225 pounds, Johnson has a solid build for a power running back. He can run and catch well and has the makings of one of the best running backs of the 2010s in Gurley. Johnson's issues, though, as his pass-blocking ability. That will likely push him to Day 2 or Day 3 of the draft. Gurley isn't a terrible player to be compared to despite only playing six seasons in the NFL. He won Offensive Rookie of the Year in 2015, Offensive Player of the Year in 2017, two All-Pro teams and three Pro Bowl teams. Gurley led the NFL in rushing and total touchdowns in a season twice (2017 and 2018) and finished with 8,336 scrimmage yards and 79 total touchdowns in 88 games. The Rams likely won't look at running back until the latter half of the draft because of Williams and 2024 third-rounder Blake Corum. However, the Williams is also in the final year of his contract and could hit free agency after the 2025 season if the Rams can't come to an agreement. If L.A. wants to add a good running back with comparable skills to another successful Rams player, Johnson is an intriguing option.
USA Today
16-04-2025
- Sport
- USA Today
Rams have been one of the most successful teams on Day 1 of NFL Draft since 2015
Rams have been one of the most successful teams on Day 1 of NFL Draft since 2015 The Rams have made just three first-round picks since 2015, but all panned out. The Los Angeles Rams haven't had many first-round picks in the past 10 years, but the ones they've drafted have been pretty outstanding. L.A. has been the second-most successful team on Day 1 of the NFL Draft since 2015, according to FTN Fantasy. The only team to finish higher than the Rams was the Detroit Lions. Despite the Rams' few picks, all of them panned out as good NFL players. The Rams had have just three picks over the past 10 drafts: Todd Gurley in 2015 (No. 10 overall), Jared Goff in 2016 (No. 1 overall) and Jared Verse in 2024 (No. 19 overall). Those picks have played in 159 Rams games since 2015, which is roughly 48% of the possible games they could have as members of the team. While this doesn't seem like a lot (that percentage ranks 25th among NFL teams, per FTN Fantasy), it's also a smaller sample size because Gurley's NFL career lasted just 87 games, Goff was traded away and has since played 65 more games and Verse is a second-year player. So other than Gurley's career being cut short by injuries, all of these players have been NFL mainstays. Meanwhile, this trio has eight Pro Bowls (three for Gurley, four for Goff and one for Verse), two All-Pro selections (Gurley) and one Defensive Rookie of the Year award (Verse). That's a lot of hardware for only three picks. The Rams currently have the No. 26 pick in the 2025 NFL draft — only their second in nine seasons. Could they strike gold again? We'll see soon enough.
