Latest news with #Hum2n
NDTV
2 days ago
- Health
- NDTV
41-Year-Old Longevity Doctor Claims His Biological Age Is 24, Reveals 3 Supplements He Takes
A 41-year-old London-based primary care doctor has claimed his biological age is 24, thanks to his comprehensive routine and supplement regimen. According to tests taken 18 months ago, Dr. Mohammed Enayat's biological age was 17 years younger than his chronological age. He used GlycanAge and TruAge PACE tests, which measure inflammation and epigenetics, to determine his biological age. Notably, Dr. Enayat, founder of Hum2n longevity clinic, has tracked his health for seven years using wearables like Oura ring and Whoop strap, along with regular blood, urine, and microbiome tests. Based on the results, he adjusts his longevity routine, including supplements. His core supplements include daily cycles of B complex, folate, magnesium, and omega-3 fatty acids. "While I believe these supplements have supported my biological age reversal, I credit them as one component in a much broader framework," Mr Enayat told Business Insider. 1. Vitamin B complex Dr. Enayat said he takes vitamin B complex and folate supplements due to a methylation gene defect that causes elevated homocysteine levels, increasing his risk of blood clots, heart attack, and stroke. The supplements help lower these levels. Generally, dietitians recommend obtaining nutrients through food and supplementing only when necessary, such as in cases of deficiency or inability to consume certain nutritious foods. Foods rich in B vitamins, like fish, poultry, legumes, and leafy greens, can also help reduce homocysteine levels. Research suggests B vitamins may be linked to improved mood and dementia prevention, but further studies are required to confirm these findings. "Even without a methylation-related gene defect, I would still consider taking a methylated B complex, particularly during periods of high stress, poor sleep, or intensive training, as these increase the demand for B vitamins," Mr Enayat said. 2. Magnesium Dr. Enayat takes magnesium bisglycinate due to his naturally low magnesium levels from dietary intake. This form is chosen for its better absorption, helping to boost his levels. Magnesium is essential for bone health, blood sugar regulation, and muscle function, and can also be found in foods like legumes and leafy greens. He reported that taking magnesium helps reduce muscle aches and improves his sleep, allowing him to fall asleep more easily. 3. Omega-3 Fatty Acids Dr. Enayat takes a daily omega-3 supplement due to his naturally low levels. Omega-3s, found in oily fish, walnuts, and chia seeds, support heart health, reduce inflammation, and lower blood pressure. While eating fatty fish weekly is proven to protect against cardiovascular disease, the benefits of supplement form are less clear. However, some research suggests omega-3 supplements may have anti-ageing effects, with a recent study finding participants who took omega-3s daily had lower biological ages.
Yahoo
2 days ago
- Health
- Yahoo
A 41-year-old longevity doctor says his 'biological age' is 24. He takes 3 supplements daily.
Dr. Mohammed Enayat, the founder of a longevity clinic, says he's reversed his "biological age" by 17 years. He told Business Insider that supplements are a part of his longevity routine. He takes B complex and folate, magnesium, and omega-3 fatty acids daily. Dr. Mohammed Enayat has access to all sorts of experimental antiaging treatments at his clinic, but a core part of his longevity routine is pretty cheap and accessible: supplements. Enayat told Business Insider that his most recent "biological age" tests, taken 18 months ago, said he was 24, or 17 years younger than his chronological age of 41. There's no consensus on how to define or measure biological age, but Enayat used GlycanAge and TruAge PACE, which measure inflammation and epigenetics, respectively. The primary care doctor, who's also the founder of London's Hum2n longevity clinic, has been closely tracking his health for the past seven years, using wearable tech, including an Oura ring and a Whoop strap, plus regular blood, urine, and microbiome tests. Enayat changes his longevity routine, including the supplements he takes, depending on the results. But he has taken what he sees as his "core" supplements, B complex and folate, magnesium, and omega-3 fatty acids, daily in cycles over the past several years, he said. "While I believe these supplements have supported my biological age reversal, I credit them as one component in a much broader framework," Enayat added. In general, dietitians recommend that people prioritize getting their nutrients from food and supplementing if they have deficiencies or are unable to eat certain nutritious foods. Enayat takes a vitamin B complex and folate supplement. "I have a methylation gene defect, which means that my homocysteine, one of the markers, rises high, which is very pro-inflammatory. So to bring that down, I have to be on a good B complex and a folate supplement," he said. Having high levels of homocysteine can increase the risk of blood clots, heart attack, and stroke. But you can lower your levels through supplementation and eating foods that contain B vitamins, including fish, poultry, legumes, seeds, eggs, dairy products, and leafy greens. More broadly, studies have linked B vitamins to better mood and the prevention of dementia, but more research is needed. "Even without a methylation-related gene defect, I would still consider taking a methylated B complex, particularly during periods of high stress, poor sleep, or intensive training, as these increase the demand for B vitamins," Enayat said. Magnesium is found in legumes, dark leafy greens, nuts, seeds, and whole grains. It plays a key role in many biological processes, including building strong bones, regulating blood sugar and blood pressure, and muscle function. Enayat's magnesium is below the recommended level, he said, because he doesn't get enough from his diet. This is relatively uncommon — about 2% of Americans have low magnesium levels. For this, he takes a form of magnesium called bisglycinate because it's easier for the body to absorb. "It works really well to bring my levels up," he said. When he takes magnesium, he finds that his muscles ache less and he falls asleep more easily. Omega-3 fatty acids, found in foods including oily fish, walnuts, and chia seeds, have been linked to better heart health, lower inflammation, and lower blood pressure. Enayat has naturally low levels of omega-3 fatty acids, so he takes a daily supplement. There's strong evidence to suggest that eating fatty fish weekly is protective against cardiovascular disease, but it's unclear whether taking it in supplement form provides the same protection. There is, however, some evidence to suggest that taking omega-3 supplements may have antiaging effects. A study on 777 participants with an average age of 75, published in the journal Nature Aging earlier this year, found that those who consumed a gram of omega-3s every day had lower "biological ages" than those who didn't. Read the original article on Business Insider
Yahoo
31-03-2025
- Health
- Yahoo
King Charles Reportedly Cancels Two International Trips Amid Fears He's 'At Risk' If He Doesn't Slow Down
King Charles is already back to public duty just days after a brief hospitalization due to side effects from his ongoing cancer treatment. After the King's brief hospitalization last Thursday, March 27, he was forced to cancel a planned visit to Birmingham the next day—though he continued working from home. Just four days after the King, 76, was hospitalized, he was back to public duty on Monday, March 31, taking part in his 'usual working week' (according to People) ahead of heading off to Italy for a royal tour alongside Queen Camilla in one week's time. To his credit, People reported that the monarch did have a 'restful' weekend at his country home, Highgrove House, but Charles' schedule remains unchanged this week, and he and Camilla will be abroad beginning April 7 as they undertake their latest royal tour. While there, the couple will celebrate their 20th wedding anniversary on April 9. The King has long been known as a workaholic, and Hello! reported that Charles is 'at risk' if he doesn't slow down his fast-paced schedule. Camilla has commented on her husband's workaholic nature in the past, saying he 'won't slow down and won't do what is told,' and has also previously said that Charles is 'not one for chilling.' Charles' younger son Prince Harry has said before that his father would sometimes fall asleep at his desk and wake up with a piece of paper stuck to his face, per Hello!, and Lady Frederick Windsor, a second cousin to the King, said, 'He works all day long, has a quick supper, and then disappears until about 4 a.m. to write letters. He cares about so many things, and he comes up with brilliant solutions.' Indeed, even after being hospitalized at The London Clinic Thursday—where Charles was originally treated for a benign enlarged prostate in January 2024, a treatment from which cancer was later detected—when Charles made it home to Clarence House later that day, he was 'said to be working on state papers and making calls from his study on Thursday evening,' Hello! reported, which added that 'while the King's work ethic is admirable, it's not ideal for his recovery.' 'Societal expectations can cause us to become workaholics, with high achievers and public figures conditioned to equate their value with productivity, making it difficult to prioritize rest, even when faced with health concerns,' said Dr. Mohammed Enayat, who is the founder of the longevity clinic Hum2n. 'Research has shown that those who struggle to detach from work experience higher levels of anxiety and sleep disturbances, both of which can negatively impact long term health.' Though his trip to Italy with Camilla is set to go on, GB News and The Sun reported that that King and Queen have canceled a visit to a luxury spa resort in Africa amid Charles' cancer treatment, and that Charles has also pulled out of an annual trip to Romania, where he was due to hike in the countryside this spring. 'He adores Romania and looks forward to visiting every year, but it would have involved just too much walking and he can't face it right now,' a source told The Sun. Following Charles' prostate procedure in January 2024, it was announced on February 5 of last year that the King had cancer, though the type and stage of which has never been publicly disclosed. (The palace did reveal last year that the King does not have prostate cancer.) The King was away from public duty until late April, and since then has kept a packed schedule, including a two-stop royal tour of Australia and Samoa last October alongside Camilla. In December, it was announced that his treatment would continue into the new year, and last Thursday's visit to the hospital was a 'minor bump in the road,' palace officials said. Of the Queen, royal biographer Katie Nicholl told OK!, 'There is clearly a rod of steel that runs through her. She is so strong, so resilient.' Nicholl added that Camilla 'also has a great sense of herself and an ability to overcome all sorts of adversity. Those are the qualities you really see in her when the going gets tough—and it did get tough last year.' Adding that Camilla has 'strength and resilience' and is 'a remarkably positive person,' Nicholl said of Camilla was not only having to care for her husband, 'but she also had to stand in for him and carry out engagements on his behalf. And she had to reassure the public that their King was okay.' 'If you look back at her time traveling up and down the country, she was always smiling for the crowds, always having a word of encouragement about the King,' Nicholl continued. 'She never let the mask slip. The laughter is spontaneous, the smile is genuine. I think she's incredibly authentic.' Read the original article on InStyle
Telegraph
03-03-2025
- Health
- Telegraph
Pig brains and oxygen chambers: How the super-rich are biohacking their way to immortality
Automatic doors open on to a cavernous lobby that could double as a spaceship. Reclining on white leather chairs are several young-looking men, glow-in-the dark intravenous drips attached to their arms. In one corner sits a man wearing what looks like a scuba mask attached to a computer. Machines beep. Doctors in lab coats murmur. This is Hum2n in Chelsea, one of London's first biohacking centres, which offers cutting-edge treatments in the booming longevity business. That scuba mask is actually a ReOxy device that mimics low oxygen conditions to stimulate lung and heart performance as well as souping up your metabolism. At the helm is Dr Mohammed Enayat, a supreme biohacker himself who has a staff of 28 and plans to open more clinics in London and Saudi Arabia. The 40-year-old doctor practises what he preaches, travelling the globe trying out treatments himself before giving them to patients. He has twice-monthly IV drips of NAD (nicotinamide adenine dinucleotide), which targets ATP (adenosine triphosphate), the cell's store of energy. He also has regular injections of Cerebrolysin, a mixture of peptides derived from pig brains, for his brain health, and epitalon to stimulate his glands to support stem-cell production. He detoxes using intravenous ozone. And he travels to California for stem-cell-derived exosome infusions. 'I'm doing it for short-, medium- and long-term vitality,' he says, 'for energy, mood, and to prevent disease progression – in short, health span.' In 2025 the pressing question in Silicon Valley and among the upper echelons of British male society is no longer, 'Who am I?' Instead they're asking, 'How can I become immortal?' Harvard geneticist David Sinclair, the pop star of the longevity world, recently addressed the topic on X. 'If you turned 100 today and felt like you do now, would you want to die? Of course not. So asking how long you want to live is pointless. The right question is, 'When do you want to get frail and sick?'' Male baby boomers watched their parents die and didn't like what they saw. This is motivating them to take their future health into their hands. I have noticed in my own circles that those willing to spend thousands on biohacking technology, and the kit that goes with it, are men. Rich men, I should add, who can afford to undertake this quest for the fountain of youth, and assume the world will want them around for another 100 years. The women I know who have the means to seek eternal life don't. They're worried about being stuck as carers for their antique men, or running around, post-menopausal and wrinkled, after their great-great-grandchildren. Then there's the economics of it all. If we live for more than a century, who's going to pay for it? Certainly not our children. And don't count on investments holding up. For the moment, though, such considerations are not on the minds of the billionaires pioneering research into longevity. Never mind superyachts, ageing well is set to become the world's most expensive hobby. The entrepreneur Bryan Johnson spends $2 million a year on living longer, while maintaining that he's investing 'for science'. Silicon Valley, and its UK outposts, is ploughing billions into the field. The biggest spender is OpenAI founder Sam Altman, who in 2022 invested £180 million in Retro Biosciences, a start-up with the stated aim of adding 10 years to a healthy human lifespan. Peter Thiel, co-founder of PayPal, has put $3.5 million into the Methuselah Foundation, a nonprofit that aims to make 90 the new 50 by 2030. Thiel has claimed it will be possible to 'reverse all human ailments in the same way we can fix the bugs of a computer program. Death will eventually be reduced from a mystery to a solvable problem.' Also on the longevity bandwagon are Jeff Bezos, Mark Zuckerberg and Google's Sergey Brin and Larry Page, all of whom have invested millions into companies such as Altos, whose Cambridge lab aims to 'reverse disease and injury'. Slapping the word 'longevity' on a package can sell anything from protein powders to cosmetics and supplements, hotel spa programmes, gym memberships and even fancy concierge services. One of these, Knightsbridge Circle, has an affiliation with a longevity clinic, Eterna Health, which advertises cell and gene therapy on its website. Netflix devoted a documentary to Johnson, whose activities have included harvesting his own son's blood to inject into himself in the name of immortality – or at least the supplements brand, Blueprint, he now touts. Pale and slim with long hair and the air of a guru, Johnson, 47, is divorced and spends much of his time alone indoors, attached to a machine. This seems to fly in the face of the fact that 'health span' is predicated on the strength of our familial relationships. Adam Rutherford, a British geneticist, recently tweeted that Johnson 'is going to get in serious medical trouble quite soon', because, despite his claims, he is 'lite' on scientific evidence. Nevertheless, according to Allied Market Research, the total value of anti-senescence therapies worldwide will grow from $25.1 billion in 2020 to $44.2 billion by 2030. Ever since Japanese scientist Dr Shinya Yamanaka identified four key genes in mice that could be reprogrammed to transform them back into their younger, healthier selves (for which he received a Nobel Prize in 2012), we've been waiting for similar developments in human medicine. But despite the promises, we haven't yet been able to turn the clock back. Even the mice from Yamanaka's initial experiments developed embryonic tumours and that was that. He's since tweaked the genetic cocktail but so far no news flashes. Dr Enayat has tried many longevity treatments, including rapamycin, which is normally used in liver-transplant patients to suppress the immune system. Off-label (used for a purpose it wasn't designed for) it has been shown to extend the life of fruit flies and worms by 20 per cent. Some American vets give it to elderly dogs. Stem cells may offer hope, but unregulated stem-cell treatments can go very wrong. In 2017 elderly patients in Florida went blind after undergoing stem-cell therapy in a private longevity clinic. Currently, the only proof of the longevity pudding is how you feel. Simon Ingram, a 70-year-old financier based in Switzerland, is one of Dr Enayat's patients. Before he started the longevity programme last year, he was struggling to work out because of low energy levels, and he slept badly. He wanted some professional guidance. Since starting at Hum2n, Ingrams has stopped drinking and cleaned up his diet (eating mostly superfoods), and has lost weight and gained muscle. He works out six days a week. 'My strength has increased by 20 per cent,' he says. 'I now have enough energy to work out in the morning then play golf in the afternoon.' Ingram visits the clinic once a month for three days for an NAD IV drip, ozone therapy, hyperbaric oxygen, cryotherapy, time in the ice closet, EmSculpt (to build muscle) and EmSella (for pelvic-floor strengthening) as well as ReOxy. He estimates that he spends £20,000 a year on all his treatments. 'My friends think I'm mad, that I always take things too far,' he admits. But as well as the gains in strength and fitness, he no longer needs to take medication for a long-term digestive issue. He plans to try peptides next. These days, leading experts in longevity medicine are looking at five specific areas. These are epigenetics, which is how your behaviour and environment change how your genes work; telomeres, the DNA sequences at the end of chromosomes, which shorten with age; senescence and cellular repair, which involves understanding why cells go rogue and how to stop it happening; stem cells, and anti-ageing regenerative medicine. The last of these involves five-hour-long NAD drips to repair DNA damage and increase energy; metabolic manipulation with Ozempic, and intermittent fasts, and all the hi-tech stuff such as wearable tech that gives instant feedback as to the state of your various organs. The current fad in longevity circles is to state your biological age (as gauged by the GlycanAge test, which measures your cellular levels of chronic inflammation), rather than your actual date of birth. Is this popularity related to the fact that everyone, including me, seems to notch up a GlycanAge that's 10 years less than their birth certificate proclaims? This had the inevitable consequence of leading Dutch positivity coach Emile Ratelband, at 69, to attempt to have his passport age adjusted downwards to 49, to reflect the age he felt himself to be, to get better Tinder dates. He failed. Diet, exercise (which promotes stem-cell creation), sleep (how we renew and detox), nutrition and, most of all, human interactions, are key to 'health span'. Something as simple as a flu jab can influence cells, says Dr Michael Roizen, chief wellness officer of the private hospital company Cleveland Clinic. 'The main thing to understand about rebooting your life is that you are a genetic engineer,' he says. Meditation alone can elongate telomeres and thus slow down ageing. So may inhaling menthol, drinking black coffee, wearing a hearing aid to stay connected, and lashings of virgin olive oil. Genes account for only 25 per cent of how we age. 'The rest is environment and lifestyle,' says Dr Thomas Perls of Boston University. 'Though this flips on its head as one approaches the age of 100.' Clinique La Prairie (CLP) in Montreux, overlooking Lake Geneva, is where the rich, the famous, and the royal come for the most advanced anti-ageing procedures in Europe under the eye of 50 medical specialists. The Swiss health resort has recently thrown itself big time into the longevity business, with plans to open 10 new resorts and 40 'hubs' worldwide. John Cleese has been coming here every 12 to 18 months for the past two decades to buy himself some extra years. Its big sell is the seven-day 'revitalisation' programme, which relies on a secret, patented CLP Extract formula, first created in 1931. Part of the CLP programme is epigenetic testing. This is a new way of pinpointing biological age and specific areas that can be targeted to reduce it. In my case, cutting back on alcohol could dramatically change my age, the doctor told me. The test is so sensitive it even detected that I had recently been to India by picking up certain pollutants. The clinic also tests bloods and stools, and screens for heavy metals in the body using a new device, the OligoScan. In order to prepare the body for the mysterious CLP Extract (which they combine with immunostimulants), guests are given multiple injections of glutathione (an antioxidant), as well as a dose of an immunomodulating bacteria along with a potent drink derived from grapes for maximum oxygen uptake in the small blood vessels. Though sadly, it's not wine. None of these steps can be skipped or fiddled or the magic won't work. On top of that is the anti-inflammatory plant-based diet, and treatments including cryotherapy, sound therapy and infratherapy in a tunnel-like sauna that makes you sweat out impurities from deep within. I could see grey flecks on the towels I used after the sauna. They were either from the pollution that I was sweating out, or perhaps my body was saying goodbye to the cadmium that can be found in even the most expensive chocolates. The youthful-looking Dr Adrian Heini oversees the revitalisation programme, which can cost upwards of £25,000 for the week. He won't reveal what goes into the age-reversing potion but says, 'We prefer to keep it natural.' Guests who come annually report feeling considerably more energetic and suffering from fewer colds. Many say they never caught Covid. An attendant told me that most clients used to be older men, but now there are young ones too. And women as well as men. Those I saw did not fraternise – tables are spread far apart in the dining room – but they ranged in age from 20s to 80s. CLP recently launched a supplement version of the age reversal formula called Age-Defy which retails for £655 for a two-month supply. It claims to combat oxidative stress, targets telomeres and includes many popular anti-senescent agents such as the plant extract fisetin, as well as a proprietary antioxidant formula. The thing about longevity is that you have to buy into the promise. Proof is thin on the ground – how can we know if someone made it to age 90 because of NAD drips rather than lucky genes? And what if all the biological tweaks make no difference at all, or even speed up cancer, which is a genuine risk of some longevity treatments? But there are profits to be made. Newly opened in Marylebone, Clarify Clinic offers to rid your blood of all microplastics, chemicals and inflammatory cytokines using a process called apheresis – and you won't get much change from £10,000. I know long-Covid sufferers who have spent £50,000 and more on this treatment abroad, only to get sicker. Henry S Lodge, the co-author of the best-selling Younger Next Year (2004), died of cancer aged 58. An early death is something many anti-ageing experts have in common. Whenever we get excited about the latest age-cracking revelation, someone comes along and sticks a pin in it. Take the 'blue zones' research, which looked at lifestyles in relatively poor areas of Sardinia, Okinawa and Costa Rica's Nicoya Peninsula, where people appeared to live to extreme old age. The study concluded that to make it to 110 you have to eat algae, chat in cafés and walk 20 miles a day (I paraphrase). However, the methodology of the research was debunked when separate researchers found that almost all the centenarians involved were in fact long dead and their relatives pretended they were still alive to keep collecting their pensions. It is, I suppose, one form of immortality. Dan Buettner, the author of The Blue Zones: Lessons for Living Longer, nevertheless now runs a mini empire of which the Blue Zones Kitchen ready-meal range (Heirloom Rice Bowl, Peach Pecan Steel Cut Oatmeal…) is one manifestation. We will crack the ageing code, or some of it at least, but for now we should curb our enthusiasm, says Dr William Mair, director of the Harvard TH Chan School Aging Initiative. 'There are increasing numbers of health influencers who have almost an evangelical following and make bold statements about how to live longer, [using] for example, ice therapy, heat shock, and so on,' he recently wrote in a Harvard publication. 'What they are doing is extrapolating data – from simpler organisms, small sample studies, and non-causal correlative studies – and telling people it's the truth. That's not how the scientific process works.' When I asked him if humans will be able to live to 300 one day, he replied, 'I don't know, yet. But that's not going to get me a lot of hits on TikTok, is it?'
