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Business Standard
2 days ago
- Business
- Business Standard
India saw over 32 million disaster displacements in a decade: IDMC report
Natural disasters such as floods and storms displaced 32.3 million people in India between 2015 and 2024, according to a report by the Geneva-based Internal Displacement Monitoring Centre (IDMC). India ranks third globally after China and the Philippines in terms of internal displacements caused by natural hazards. The report highlights that disasters triggered 264.8 million internal displacements across 210 countries and territories over the past decade, with East and South Asian countries among the worst affected. China recorded 46.9 million displacements, followed closely by the Philippines with 46.1 million. 'At the country level, Bangladesh, China, India, the Philippines and the US recorded the highest figures over the past decade,' the report stated. Floods and storms behind 90% of global disaster displacement According to IDMC, 90 per cent of global disaster-related displacements between 2015 and 2024 were caused by floods and storms. Storms alone triggered 120.9 million displacements during this period, while floods were responsible for 114.8 million. Cyclones, including Cyclone Amphan in 2020, accounted for 92 per cent of all storm-related displacements worldwide. The report noted a rising trend in disaster-induced displacement, driven by more frequent and intense hazards, improved data collection at the national level, and enhanced global monitoring capacities. India recorded 5.4 million displacements in 2024 alone In 2024, a record 45.8 million internal displacements were reported globally—well above the decadal average of 26.5 million. India accounted for 5.4 million of these, marking the highest annual figure recorded in the country over the past 12 years. Many of these movements were preemptive evacuations, according to the report, reflecting the efforts of governments and local communities in disaster-prone areas to save lives and minimise injury. However, millions remain displaced for months or years after major floods, storms and other hazards. Vulnerable populations hit hardest The IDMC emphasised that disaster displacement disproportionately affects the most vulnerable populations. 'They are often forced to flee repeatedly and for longer periods of time, which heightens their pre-existing vulnerabilities and reinforces social inequalities,' the report stated. Climate conditions could displace 32 million annually The IDMC warned that, under current climate conditions, an annual average of 32 million people globally are likely to be displaced due to hazards such as riverine and coastal flooding, drought and cyclonic winds. That figure could double if global temperatures rise more than 1.5°C above pre-industrial levels (1850–1890), the report cautioned. 'Left unaddressed, disaster displacement will be a major obstacle to the achievement of global goals, such as those set by the Sendai Framework for Disaster Risk Reduction, the Paris Agreement and the 2030 Agenda for Sustainable Development,' it concluded.
New Indian Express
3 days ago
- Business
- New Indian Express
India recorded over 3.2 crore disaster displacements in a decade: IDMC
NEW DELHI: IDMC India recorded 32.3 million (3.23 crore) internal displacements due to disasters, such as floods and storms, between 2015 and 2024, the third highest in the world after China and the Philippines, according to a new report. The report by the Geneva-based Internal Displacement Monitoring Centre (IDMC) said disasters triggered 264.8 million internal displacements or forced movements across 210 countries and territories during this period. East and South Asia were the most affected regions. "At the country level, Bangladesh, China, India, the Philippines and the US recorded the highest figures over the past decade," the report said. China recorded 46.9 million internal displacements and the Philippines 46.1 million. The report said that nearly 90 per cent of global disaster displacements were the result of floods and storms. "Storms triggered most of the world's disaster displacements between 2015 and 2024, accounting for 120.9 million movements," it said. Floods triggered 114.8 million displacements during the same period. Cyclones, including Amphan in 2020, accounted for about 92 per cent of all storm displacements globally. The report said disasters have triggered an increasing number of internal displacements since 2015, the result in part of more frequent and intense hazards but also improved data at the national level and better monitoring capacity at the global level. In 2024 alone, 45.8 million internal displacements were recorded, the highest on record and far above the decadal average of 26.5 million.
Time of India
3 days ago
- Business
- Time of India
India recorded over 3.2 crore disaster displacements in a decade: IDMC
India recorded 32.3 million (3.23 crore) internal displacements due to disasters, such as floods and storms, between 2015 and 2024, the third highest in the world after China and the Philippines, according to a new report. The report by the Geneva-based Internal Displacement Monitoring Centre (IDMC) said disasters triggered 264.8 million internal displacements or forced movements across 210 countries and territories during this period. East and South Asia were the most affected regions. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like News For Jack Nicholson, 87, He Has Been Confirmed To Be... Reportingly Undo "At the country level, Bangladesh, China, India, the Philippines and the US recorded the highest figures over the past decade," the report said. China recorded 46.9 million internal displacements and the Philippines 46.1 million. Live Events The report said that nearly 90 per cent of global disaster displacements were the result of floods and storms. "Storms triggered most of the world's disaster displacements between 2015 and 2024, accounting for 120.9 million movements," it said. Floods triggered 114.8 million displacements during the same period. Cyclones, including Amphan in 2020, accounted for about 92 per cent of all storm displacements globally. The report said disasters have triggered an increasing number of internal displacements since 2015, the result in part of more frequent and intense hazards but also improved data at the national level and better monitoring capacity at the global level. In 2024 alone, 45.8 million internal displacements were recorded, the highest on record and far above the decadal average of 26.5 million. India recorded 5.4 million (54 lakh) displacements last year due to floods, storms and other disasters, the highest figure in 12 years. The report said many of the displacements were pre-emptive evacuations, testimony to the efforts of governments and local communities in disaster-prone countries to save lives and prevent injuries. However, "millions of people remain displaced for months or years after fleeing major storms, floods and other natural hazards". The IDMC emphasised that disaster displacement "affects the most vulnerable more severely". "They are often forced to flee repeatedly and for longer periods of time, which heightens their pre-existing vulnerabilities and reinforces social inequalities," it said. It warned that under current climate conditions, an annual average of 32 million people worldwide are likely to be displaced by riverine and coastal floods, drought and cyclonic winds in any given future year. That risk increases by 100 per cent if Earth's average temperature rises by more than 1.5 degrees Celsius compared to the start of the industrial revolution (1850-1890), it said. The 1.5 degrees Celsius threshold is a target that countries agreed to at the Paris climate conference in 2015 to avoid the worst impacts of climate change. "Left unaddressed, disaster displacement will be a major obstacle to the achievement of global goals, such as those set by the Sendai Framework for Disaster Risk Reduction, the Paris Agreement and the 2030 Agenda for Sustainable Development," the report said.
Yahoo
28-05-2025
- Business
- Yahoo
InflaRx Announces Outcome of Interim Analysis for Vilobelimab Phase 3 Trial in Pyoderma Gangrenosum
JENA, Germany, May 28, 2025 (GLOBE NEWSWIRE) -- InflaRx N.V. (Nasdaq: IFRX), a biopharmaceutical company pioneering anti-inflammatory therapeutics targeting the complement system, today announced that the Independent Data Monitoring Committee (IDMC) conducting the unblinded interim analysis for the Phase 3 trial for vilobelimab in pyoderma gangrenosum (PG), recommended that the trial be stopped due to futility. This recommendation was based on data analysis of the first 30 patients enrolled in the study, with no unexpected adverse events noted by the IDMC. InflaRx as the study sponsor remains blinded to the study results. Prof. Niels C. Riedemann, Chief Executive Officer and Founder of InflaRx, said: 'We would like to thank the dedicated physicians and pyoderma gangrenosum patients for their participation in this pioneering study targeting a significant unmet need. While the outcome is not what we had hoped it would be, InflaRx remains committed to its goal of developing new therapies for underserved patients with chronic immune-dermatological conditions, including with our oral inhibitor of C5aR, INF904, with data expected this summer.' InflaRx intends to discontinue further development of vilobelimab in the PG indication and to prioritize its resources on INF904, with Phase 2a data readouts in chronic spontaneous urticaria (CSU) and hidradenitis suppurativa (HS) anticipated this summer. The Company is also considering additional cost savings and redirection of resources toward the goal of extending the Company's existing cash runway. GOHIBIC (vilobelimab) remains available in the US where it has been granted Emergency Use Authorization by the Food and Drug Administration (FDA) for the treatment of COVID-19 in hospitalized adults when initiated within 48 hours of receiving invasive mechanical ventilation (IMV) or extracorporeal membrane oxygenation (ECMO). The Company will continue its support of the BARDA-funded Phase 2 clinical platform study. In the EU, GOHIBIC (vilobelimab) has been granted marketing authorization under exceptional circumstances for the treatment of adult patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS) who are receiving systemic corticosteroids as part of standard of care and receiving IMV with or without ECMO. InflaRx (Nasdaq: IFRX) is a biopharmaceutical company pioneering anti-inflammatory therapeutics by applying its proprietary anti-C5a and anti-C5aR technologies to discover, develop and commercialize highly potent and specific inhibitors of the complement activation factor C5a and its receptor C5aR. C5a is a powerful inflammatory mediator involved in the progression of a wide variety of inflammatory diseases. InflaRx's lead product candidate, vilobelimab, is a novel, intravenously delivered, first-in-class, anti-C5a monoclonal antibody that selectively binds to free C5a and has demonstrated disease-modifying clinical activity and tolerability in multiple clinical studies in different indications. InflaRx is also developing INF904, an orally administered small molecule inhibitor of C5a-induced signaling via the C5a receptor. InflaRx was founded in 2007, and the group has offices and subsidiaries in Jena and Munich, Germany, as well as Ann Arbor, MI, USA. For further information, please visit InflaRx GmbH (Germany) and InflaRx Pharmaceuticals Inc. (USA) are wholly owned subsidiaries of InflaRx N.V. (together, InflaRx). In the U.S., GOHIBIC (vilobelimab) has been granted an Emergency Use Authorization by the Food and Drug Administration (FDA) for the treatment of COVID-19 in hospitalized adults when initiated within 48 hours of receiving invasive mechanical ventilation (IMV) or extracorporeal membrane oxygenation (ECMO). The emergency use of GOHIBIC (vilobelimab) is only authorized for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of drugs and biological products during the COVID-19 pandemic under Section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the declaration is terminated, or authorization revoked sooner. GOHIBIC (vilobelimab) is an investigational drug that has not been approved by the FDA for any indication, including for the treatment of COVID-19. There is limited information known about the safety and effectiveness of using GOHIBIC (vilobelimab) to treat people in the hospital with COVID-19. Please see additional information in the Fact Sheet for Healthcare Providers, Fact Sheet for Patients and Parents/Caregivers and FDA Letter of Authorization on the GOHIBIC website In the EU, GOHIBIC (vilobelimab) has been granted marketing authorization under exceptional circumstances for the treatment of adult patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS) who are receiving systemic corticosteroids as part of standard of care and receiving invasive mechanical ventilation (IMV) with or without extracorporeal membrane oxygenation (ECMO). The EU approval of GOHIBIC (vilobelimab) is supported by the previously announced results of the multicenter Phase 3 PANAMO trial, one of the largest 1:1 randomized, double-blind, placebo-controlled trials in invasively mechanically ventilated COVID-19 patients in intensive care units. The results showed that vilobelimab treatment improved survival with a relative reduction in 28-day all-cause mortality of 23.9% compared to placebo in the global data set. The data were published in The Lancet Respiratory Medicine. A marketing authorization under exceptional circumstances is recommended when the benefit/risk assessment is determined to be positive but, due to the rarity of the disease, it's unlikely that comprehensive data can be obtained under normal conditions of use. Under the terms of GOHIBIC's (vilobelimab's) approval in the EC, InflaRx will provide annual updates to EMA on the previously announced clinical platform study planned by the Biomedical Advanced Research and Development Authority (BARDA). Vilobelimab is included in this study as one of three new potential therapies for treating ARDS. The COVID-19 related work described herein was partly funded by the German Federal Government through grant number 16LW0113 (VILO-COVID). All responsibility for the content of this work lies with InflaRx. There is limited clinical data available for GOHIBIC (vilobelimab). Serious and unexpected adverse events (AEs) may occur that have not been previously reported with GOHIBIC (vilobelimab) use. GOHIBIC (vilobelimab) has been associated with an increase of serious infections. In patients with COVID-19, monitor for signs and symptoms of new infections during and after treatment with GOHIBIC (vilobelimab). Hypersensitivity reactions have been observed with GOHIBIC (vilobelimab). If a severe hypersensitivity reaction occurs, administration of GOHIBIC (vilobelimab) should be discontinued and appropriate therapy initiated. The most common adverse reactions (incidence ≥3%) are pneumonia, sepsis, delirium, pulmonary embolism, hypertension, pneumothorax, deep vein thrombosis, herpes simplex, enterococcal infection, bronchopulmonary aspergillosis, hepatic enzyme increased, urinary tract infection, hypoxia, thrombocytopenia, pneumomediastinum, respiratory tract infection, supraventricular tachycardia, constipation, and rash. Healthcare providers and/or their designee are responsible for mandatory FDA MedWatch reporting of all medication errors and serious AEs or deaths that occur during GOHIBIC (vilobelimab) treatment and are considered to be potentially attributable to GOHIBIC (vilobelimab). Report side effects to the FDA at 1-800-FDA-1088 or In addition, side effects can be reported to InflaRx at: pvusa@ For the full prescribing information and additional important safety information, please visit The COVID-19 related work described herein was partly funded by the German Federal Government through grant number 16LW0113 (VILO-COVID). All responsibility for the content of this work lies with InflaRx. Vilobelimab is a first-in-class monoclonal anti-human complement factor C5a antibody, which highly and effectively blocks the biological activity of C5a and demonstrates high selectivity towards its target in human blood. Thus, vilobelimab leaves the formation of the membrane attack complex (C5b-9) intact as an important defense mechanism of the innate immune system, which is not the case for molecules blocking C5. In pre-clinical studies, vilobelimab has been shown to control the inflammatory response-driven tissue and organ damage by specifically blocking C5a as a key 'amplifier' of this N.V. MC Services AG Jan Medina, CFAVice President, Head of Investor RelationsEmail: IR@ Katja Arnold, Laurie Doyle, Dr. Regina LutzEmail: inflarx@ Europe: +49 89-210 2280U.S.: +1-339-832-0752 FORWARD-LOOKING STATEMENTSThis press release contains forward-looking statements. All statements other than statements of historical fact are forward-looking statements, which are often indicated by terms such as 'may,' 'will,' 'should,' 'expect,' 'plan,' 'anticipate,' 'could,' 'intend,' 'target,' 'project,' 'estimate,' 'believe,' 'predict,' 'potential' or 'continue,' among others. Forward-looking statements appear in a number of places throughout this release and may include statements regarding our intentions, beliefs, projections, outlook, analyses, current expectations and the risks, uncertainties and other factors described under the headings, 'Risk factors' and 'Cautionary statement regarding forward looking statements', in our periodic filings with the SEC. These statements speak only as of the date of this press release and involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. 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The Guardian
23-05-2025
- Climate
- The Guardian
‘I don't want to be here. But we can't go home': what life is like for people forced to flee floods and fighting
In 2024, the number of internally displaced people around the world reached 83.4m, the highest figure ever recorded. Men, women, children, whole families and generations have been forced to flee their homes within their country as a result of conflict, violence, or natural disasters. 'Internal displacement rarely makes the headlines, but for those living it, the suffering can last for years,' says Jan Egeland, secretary general of the Norwegian Refugee Council, commenting on the latest figures from the Internal Displacement Monitoring Centre (IDMC). Here, three people tell us what it has meant to be forced from their homes. Bangladesh is one of the world's most climate-vulnerable countries. The number of internally displaced people due to natural disasters has risen for four consecutive years and reached 2.4 million in 2024, according to the IDMC report. Baby Begum is 40 and has two disabled sons. She was first displaced by the catastrophic floods of 2022. 'Every year, before the monsoon season begins, I get this anxious feeling in the pit of my stomach. It starts with the first drops of rain and steadily gets worse. I grew up in Sunamganj, in north-east Bangladesh, where the monsoon season brings heavy rainfall for months at a time; about 80% of Bangladesh's yearly rainfall occurs from June to October, and by the end of it, almost a third of our country is underwater. I know water is essential for survival but it also has the power to destroy everything in its path. I have learned this first-hand. In June 2022, catastrophic flash floods – the worst Bangladesh had seen in a century – inundated much of my home town, killing people in its wake, washing away my village and leaving thousands of people displaced. My family was among them and in the course of just a few days, we lost everything; our home, our crops and cattle, and our entire life savings. I was at work when the flood water started rising and by the time I got home, my village was empty. The rescue boats that arrived to carry people to emergency shelters had already left and my family was stuck. My husband, Shafiq, had been watching our sons, Yunus and Bablu, who are both disabled and autistic. They were terrified. It took only a few hours for our house to be under water. We scrambled on to the roof and cried out desperately for help as the water continued to rise. I was convinced we would all drown. Although I can swim, my boys can't and so we decided, if we had to die, we would die together. Luckily, a fisherman with a boat rescued us at the last minute. We were taken to an emergency shelter but from there, things only got worse. We thought it would be temporary but we were stuck there with hundreds of other families, all squeezed together in a crowded, unsanitary space. We had to queue for hours just to use the washroom and my boys would end up wetting themselves. It was a complete nightmare. With our home destroyed, we were forced to leave. We went from one shelter to another and then, in 2023, we moved into a ramshackle hut in an overcrowded slum in nearby Sylhet, where we hoped we would find work. I got a job as a housemaid and Shafiq became a rickshaw driver. But a few months later, he fell off his bike and seriously injured his back, leaving him unable to work. I became the sole breadwinner of my family, earning only 5,000 taka [£30] a month. The past few years have been really difficult. After losing everything to the floods, we have had to start again from scratch. We had once saved enough to send our sons to a special school but now that dream feels impossible. We only have enough to get by and even that is a daily struggle. In 2024, the floods returned. Our home, made from rusted tin sheets, was partly destroyed and I can't afford to get the roof fixed so even during slight rainfall, it becomes damp and muddy. The air is unbearable. We all feel suffocated. My children get sick often and I can't afford medication. I constantly feel like I have failed them. I tell them this situation is only temporary but in reality, I don't think things will ever get better for us. We didn't just lose our home, but our close ties with our family and neighbours. The floods have washed away all our hopes and dreams. In my village, we knew everyone and there were always people around who we could rely on for help. My sons felt safe and secure. They had friends. But now we have lost all of that – and it feels like we are never getting it back. As told to Thaslima Begum In 2024, Sudan hosted 11.6 million internally displaced people, the most ever recorded in a single country, as fighting between the Sudanese armed forces and the Rapid Support Forces (RSF) created the world's worst humanitarian crisis. Mubarak Ibrahim is 50 and has five children. He and his family were forced to flee his village, which is Zaghawa, an African ethnic group repeatedly targeted by the RSF. 'We had no choice but to leave. They were bombing us 24 hours a day with all kinds of heavy weapons. Then, three weeks ago, the RSF attacked our village, Saloma, in North Darfur. They burned down houses, shot civilians in the street. Most of those they killed were children, women or old men. I have five children: two girls and three boys aged between three and 13. I needed to get them out. Sign up to Global Dispatch Get a different world view with a roundup of the best news, features and pictures, curated by our global development team after newsletter promotion At night, while the village was under attack, we managed to escape and headed west. It was difficult and very dangerous. One of my daughters, who is 11, was shot in the hand by a stray bullet. We left everything behind in Saloma, where I had lived for decades. Although now officially displaced, the truth is that I had spent my entire life in a camp for displaced people: Saloma lies close to the original site of the Zamzam camp, built in 2004 to house huge numbers of people displaced by the war in Darfur. Over time, its numbers increased to an estimated 700,000, becoming Sudan's largest displacement camp. As it grew, Zamzam engulfed my village, which is now actually in the heart of it. After we escaped from Saloma, we walked for about 30km [18 miles] to the small town of Tawila. Even there we are not feeling safe, especially the children and women because they fear the militia will attack them. Yet it is better than before, although we have nothing. People are sleeping under trees or outdoors in valleys. Some have headed into the Jebel Marra hills. There is no food and we are also very short of water. We have no source of water and we have entered the summer season. Temperatures are already very high. Some people who fled the RSF attack on Zamzam died of thirst on the way to Tawila. It was mainly old women who died after running out of water on journeys of up to 50km on foot. There is also no medicine. It has been very difficult trying to help my daughter after she was shot. Only traditional medicine is available. We have to use local materials to treat her. No outside organisation can reach us – there is no access. Already the situation is critical. Also, my mother is 75 years old and very sick. I am scared she could die because she has high blood pressure and other illnesses. Every day more people are arriving from Zamzam or El Fasher, where it is very unsafe. Still the people keep on arriving in Tawila, coming from different directions, using longer routes. Daily, the numbers of Darfur's displaced continues to grow. As told to Mark Townsend Colombia has one of the world's most severe internal displacement crises, with nearly 7 milliondriven by decades of conflict and violence. By mid-2024, nearly 7 million people had been displaced within the country, with the government recognising them as eligible for aid and reparations. Continued clashes between non-state armed groups affected about 183,400 people in the first half of 2024 alone. Rosmira is 30, widowed and has four young children. They were forced out of their village by clashes between the military and armed paramilitary groups. 'I am a leader and spokesperson for the Emberá-Katío Indigenous people in the Chocó region, where I come from. I have been living in Bogotá for several years now because my home has become a war zone, and we cannot return until the government guarantees our safety. The ELN [National Liberation Army, Colombia's largest paramilitary group], armed men with machine guns, are clashing with the military there, and we are caught in the crossfire. It's a 'red zone'. At times, armed groups – these men in green uniforms with guns – threaten or clash with us over territory. They attempt to recruit our children and encroach on our land for mining, so we have to protect ourselves with the Indigenous guard. We just want to live in peace. When I was 15, they took me once and raped me. I was out gathering food. It was horrible. Now, 150 families live here in the tents we put up in the Parque Nacional, one of Bogotá's most-loved parks. I don't want to be here. I don't like it. It's cold and wet, and we are always ill. But we can't go home as it's too dangerous. It's really tough getting by. I have four children aged between two and 11 years. My husband died two years ago during the pandemic. I make artisanal goods such as bracelets, necklaces and clothing, and sell them on the street. But it's not every day people want to buy them. So sometimes we have to go hungry. There is no other work for us. My region is incredibly green and mountainous, with waterfalls and clear, pristine rivers flowing through it. There are no roads. I still have cousins, aunties and uncles living there. My parents are dead. At home, we used to rely on the plantains, cassava and corn we grew on the land. There were many animals, such as birds and monkeys, but they have been absent since the conflict began. The army has been fumigating the area with chemicals since 2015 to prevent the armed men from growing coca crops, and it seems to have devastated the entire natural environment. Now, we cannot cultivate crops; the land yields very little. Since 2019, I have lived in Bogotá in five different places. I have been taking Spanish classes with a teacher at a college, so I can now understand a little. We have mostly lived in camps we have set up in parks, but the conditions were poor, so we had to move on. About 400 of us returned to live in this park again on Monday to protest and urge the government to take action. They never fulfil their promises. Some of us want the government to help us in returning home, while others seek support to move to a different place. Local people don't want us here, and they can sometimes be aggressive. It makes me sad; they ought to show us some respect. We don't want to be here either – but we have no choice. As told to Luke Taylor
