Latest news with #IIT-I
Time of India
28-05-2025
- Health
- Time of India
IIT-I study to help develop therapies & precise diagnostics for Covid symptoms
Indore: A study by the Indian Institute of Technology, Indore, (IIT-I) in collaboration with top Indian institutions, revealed how different variants of Covid-19 virus affected the human body and led to varying levels of disease severity. The findings show how different Covid-19 variants influence the body in unique ways, causing major disruptions in metabolic and hormonal pathways. This research was led by Dr Hem Chandra Jha from IIT-I and Dr Nirmal Kumar Mohakud from KIMS Bhubaneswar, with support from the Indian Council of Medical Research (ICMR) and IIT-I. IIT-I director professor Suhas S Joshi said, "This study is a testament to the strength of interdisciplinary collaboration and cutting-edge research at IIT-Indore. Understanding the long-term impact of Covid-19 at a molecular level is vital for preparing better healthcare responses and designing targeted treatments." Using clinical data from 3,134 Covid-19 patients from the first and second waves in India, researchers applied machine learning to identify nine critical parameters related to disease severity, such as C-reactive protein (CRP), D-dimer, ferritin, neutrophils, white blood cell (WBC) count, lymphocytes, urea, creatine, and lactate dehydrogenase (LDH). In addition to analysing patient data, the researchers studied lung and colon cells that were exposed to different spike proteins from these virus variants. Dr Hem Chandra Jha, an associate professor at IIT-I added, "Our findings reveal how different Covid-19 variants influence the body in unique ways, particularly the Delta variant, which caused major disruptions in metabolic and hormonal pathways. This research could help develop precise diagnostics and therapies to manage long Covid-19 symptoms more effectively." According to the findings, the Delta variant showed the most significant disruptions in the body's chemical balance. It affected pathways related to catecholamine and thyroid hormone production, leading to complications, including silent heart failure and thyroid dysfunction. These findings were further supported by a meta-analysis that pointed to disruptions in urea and amino acid metabolism. The study also involved advanced technologies like multi-omics and Raman spectroscopy, used by Prof Rajesh Kumar's team at IIT-Indore to map these disruptions. Patient data analysis was guided by Professor Sonali Agarwal from IIIT Allahabad.
Time of India
27-05-2025
- Health
- Time of India
IIT-I study may help to develop precise diagnostics & therapies for Covid-19 symptoms
Indore: A study by the Indian Institute of Technology, Indore, ((IIT-I) in collaboration with top Indian institutions, revealed how different variants of Covid-19 virus affected the human body and led to varying levels of disease severity. The findings show how different Covid-19 variants influence the body in unique ways, causing major disruptions in metabolic and hormonal pathways. This research was led by Dr Hem Chandra Jha from IIT-I and Dr Nirmal Kumar Mohakud from KIMS Bhubaneswar, with support from the Indian Council of Medical Research (ICMR) and IIT-I. IIT-I director professor Suhas S Joshi said, "This study is a testament to the strength of interdisciplinary collaboration and cutting-edge research at IIT-Indore. Understanding the long-term impact of Covid-19 at a molecular level is vital for preparing better healthcare responses and designing targeted treatments." Using clinical data from 3,134 Covid-19 patients from the first and second waves in India, researchers applied machine learning to identify nine critical parameters related to disease severity, such as C-reactive protein (CRP), D-dimer, ferritin, neutrophils, white blood cell (WBC) count, lymphocytes, urea, creatine, and lactate dehydrogenase (LDH). by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Edema nas pernas? Pingue isso na água antes de dormir! A arte do herbalismo Undo In addition to analysing patient data, the researchers studied lung and colon cells that were exposed to different spike proteins from these virus variants. Dr Hem Chandra Jha, an associate professor at IIT-I added, "Our findings reveal how different Covid-19 variants influence the body in unique ways, particularly the Delta variant, which caused major disruptions in metabolic and hormonal pathways. This research could help develop precise diagnostics and therapies to manage long Covid-19 symptoms more effectively." According to the findings, the Delta variant showed the most significant disruptions in the body's chemical balance. It affected pathways related to catecholamine and thyroid hormone production, leading to complications, including silent heart failure and thyroid dysfunction. These findings were further supported by a meta-analysis that pointed to disruptions in urea and amino acid metabolism. The study also involved advanced technologies like multi-omics and Raman spectroscopy, used by Prof Rajesh Kumar's team at IIT-Indore to map these disruptions. Patient data analysis was guided by Professor Sonali Agarwal from IIIT Allahabad. Authors, who contributed to this study include, Budhadev Baral, Vaishali Saini, Siddharth Singh, Tarun Prakash Verma, Deb Kumar Rath, Jyotirmayee Bahinipati, Priyadarsini Panda, Shubhransu Patro, Namrata Misra, Manas Ranjan Behera, Kartik Muduli, Hamendra Singh Parmar, Ajay Kumar Meena and Soumya R Mohapatra.
Time of India
30-04-2025
- Science
- Time of India
IIT-I to launch MA English literature & linguistics programme in July 2025
Indore: Indian Institute of Technology (IIT) Indore announced the launch of a two-year MA English (Literature and Linguistics) programme, with the session starting in July 2025. This innovative course, offered by the School of Humanities and Social Sciences, features a distinctive syllabus designed to blend theoretical knowledge with practical application. The MA programme will provide students with specialisations in various emerging fields, including Digital Humanities , Medical Humanities, Language Teaching , Applied Linguistics, Language Documentation and interdisciplinary research. "This curriculum aims to equip students with critical thinking abilities and practical skills that are essential for flourishing in contemporary careers related to language and literature. With a strong emphasis on the evolving intersections of language and technology, the programme equips students for diverse roles in teaching, publishing, research, media, language technology, international communication and more," IIT-I said in a statement on Wednesday. The structure includes hands-on projects, research opportunities, internships and real-world applications to ensure students are well-prepared for the job market, said IIT-I. "Prospective candidates with a three-year undergraduate degree from any discipline and a qualifying score in the GATE Humanities and Social Sciences (HSS) XH C2 or XH C3 are encouraged to apply. Applications are open until May 18, 2025, for the July 2025 session," the statement said. Classes will be led by faculty members who are experts in literature, linguistics and interdisciplinary studies, ensuring an enriching learning experience. Additionally, the programme offers a fellowship in the second year to support academic pursuits and enhance the educational journey of its students. This new initiative from IIT Indore marks a significant step towards broadening the scope of humanities education in India, highlighting the importance of language and literature in a rapidly evolving world.
Time of India
30-04-2025
- Health
- Time of India
IIT-I to develop tech translation research park
Indore: Indian Institute of Technology, Indore (IIT-I), is developing a Technology Translation Research Park (TTRP) with an aim to enhance digital health solutions and creating a seamless digital health ecosystem in the country. The advanced facility at IIT-I in digital healthcare to be set up under the National Mission on Interdisciplinary Cyber-Physical Systems (NM-ICPS) will work to bridge the gap between urban and rural healthcare services, leveraging telemedicine , electronic health records (EHRs), artificial intelligence-driven diagnostics and personalised medicine and care. The institute received a nod from the department of science and technology and governing body of NMICPS led by Kris Gopalakrishnan, founder of Infosys, to upgrade IIT-I's technology innovation hub Drishti CPS Foundation into a TTRP with an outlay of Rs 250 crore for next three years in tranches. Of the total proposed amount Rs 52 crore has been received by the foundation. "The new TTRP comes as a great validation of the initiatives on digital healthcare that has been incubated in IIT-I. We look forward to extending the mandate of IIT-I Drishti CPS Foundation into the digital healthcare through this new TTRP," said IIT-I director professor Suhas S Joshi. IIT-Indore established the Drishti CPS Foundation in 2020, which has so far supported over 150 technology projects and startups with funds and mentoring. Drishti CPS Foundation CEO Aditya Vyas said, "The research park will cater to the growing need of the nation in creating a robust digital health infrastructure. Drishti CPS is developing a flagship unified human digital twin platform - CharakDT. The novel, systematic and scalable architecture of CharakDT allows a unique way of creating individual health models (twins) for each patient by aggregating contextual data from multifarious sources and implementing large-scale AI models across dimensions of organ physics, demography, diagnostic tools, and environment."
Time of India
29-04-2025
- Health
- Time of India
IIT-I to develop Technology Translation Research Park to boost digital healthcare
Indore: Indian Institute of Technology, Indore (IIT-I), is developing a Technology Translation Research Park (TTRP) with an aim to enhance digital health solutions and creating a seamless digital health ecosystem in the country. Tired of too many ads? go ad free now The advanced facility at IIT-I in digital healthcare to be set up under the National Mission on Interdisciplinary Cyber-Physical Systems (NM-ICPS) will work to bridge the gap between urban and rural healthcare services, leveraging telemedicine , electronic health records (EHRs), artificial intelligence-driven diagnostics and personalised medicine and care. The institute received a nod from the department of science and technology and governing body of NMICPS led by Kris Gopalakrishnan, founder of Infosys, to upgrade IIT-I's technology innovation hub Drishti CPS Foundation into a TTRP with an outlay of Rs 250 crore for next three years in tranches. Of the total proposed amount Rs 52 crore has been received by the foundation. "The new TTRP comes as a great validation of the initiatives on digital healthcare that has been incubated in IIT-I. We look forward to extending the mandate of IIT-I Drishti CPS Foundation into the digital healthcare through this new TTRP," said IIT-I director professor Suhas S Joshi. IIT-Indore established the Drishti CPS Foundation in 2020, which has so far supported over 150 technology projects and startups with funds and mentoring. Drishti CPS Foundation CEO Aditya Vyas said, "The research park will cater to the growing need of the nation in creating a robust digital health infrastructure. Drishti CPS is developing a flagship unified human digital twin platform — CharakDT. The novel, systematic and scalable architecture of CharakDT allows a unique way of creating individual health models (twins) for each patient by aggregating contextual data from multifarious sources and implementing large-scale AI models across dimensions of organ physics, demography, diagnostic tools, and environment." The TTRP will also give a huge boost to translational research activities in other domain of research at IIT-I, Vyas said.
