Latest news with #IRLAB
Yahoo
4 days ago
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IRLAB Participates in Aktiespararna's Event
GOTHENBURG, SE / / June 4, 2025 / IRLAB Therapeutics (STO:IRLAB-A)(FRA:6IRA) - Gothenburg, Sweden, June 4, 2025 - IRLAB Therapeutics AB (Nasdaq Stockholm: IRLAB A), a company discovering and developing novel treatments for Parkinson's disease, today announced that the company will give a presentation at Aktiedagarna in Stockholm on June 10-11. IRLAB is presented by Kristina Torfgård, CEO, who will give a 25-minute company presentation, including a Q&A session, on June 10 at 16.25 CEST. The event is held at Birger Jarl Conference, Birger Jarlsgatan 61 A in Stockholm. More information can be found on Aktiespararna's webpage: For more information Kristina Torfgård, CEOPhone: +46 730 60 70 99E-mail: About IRLAB IRLAB discovers and develops a portfolio of transformative treatments for all stages of Parkinson's disease. The company originates from Nobel Laureate Prof Arvid Carlsson's research group and the discovery of a link between brain neurotransmitter disorders and brain diseases. Mesdopetam (IRL790), under development for treating levodopa-induced dyskinesias, has completed Phase IIb and is in preparation for Phase III. Pirepemat (IRL752), currently in Phase IIb, is being evaluated for its effect on balance and fall frequency in Parkinson's disease. IRL757, a compound being developed for the treatment of apathy in neurodegenerative disorders, is in Phase I. In addition, the company is developing two preclinical programs, IRL942 and IRL1117, towards Phase I studies. IRLAB's pipeline has been generated by the company's proprietary systems biology-based research platform Integrative Screening Process (ISP). Headquartered in Sweden, IRLAB is listed on Nasdaq Stockholm (IRLAB A). For more information, please visit . Attachments IRLAB participates in Aktiespararna's event - Aktiedagarna SOURCE: IRLAB Therapeutics View the original press release on ACCESS Newswire Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
28-05-2025
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IRLAB Reports Positive Results from the Second Part of a Phase I Study with IRL757
GOTHENBURG, SE / / May 28, 2025 / IRLAB Therapeutics (STO:IRLAB-A)(FRA:6IRA) - Gothenburg, Sweden, May 28, 2025 - IRLAB Therapeutics AB (Nasdaq Stockholm:IRLAB A), a company that discovers and develops new treatments for Parkinson's disease, today announces the company has successfully completed the second and final part of its clinical Phase I study, in which the drug candidate IRL757, being developed for the treatment of apathy, was administered in multiple ascending doses (MAD). The results show that IRL757 is well absorbed and provides good exposure in the body following ten days of dosing. All participants completed the study, and no serious adverse events were recorded. The safety, tolerability and pharmacokinetic profile of IRL757 support continued clinical development. "We are very pleased that IRL757 is well absorbed and provides good exposure in the body while demonstrating excellent tolerability and a favorable safety profile. These results give us a strong foundation for the continued clinical development of the drug candidate, which has the potential to treat and counteract apathy in millions of patients with neurodegenerative diseases," says Dr. Joakim Tedroff, MD, Chief Medical Officer at IRLAB. The Phase I study has been funded by The Michael J. Fox Foundation for Parkinson's Research (MJFF) through a grant of just over SEK 20 million. MJFF is the world's largest non-profit funder of Parkinson's disease research, and the organization's support for IRL757 means a strong external validation of the project's goals and potential. Based on the positive results from the completed Phase I studies, a clinical Phase Ib study in Parkinson's disease and apathy has been initiated in cooperation with The McQuade Center for Strategic Research and Development (MSRD), a member of the global Otsuka family of pharmaceutical companies. The first patients are expected to be enrolled in the study in the second half of 2025. IRLAB and MSRD formed a collaboration in May 2024 to advance IRL757 through proof-of-concept trials as a potential treatment of apathy. Apathy is characterized by indifference, resignation and a lack of response to what is happening in the outside world. The condition often leads to significant disability and caregiver distress, affecting a substantial proportion of people living with Parkinson's, Alzheimer's and other diseases related to the central nervous system. Currently, there are no drugs on the market to treat apathy. IRLAB's drug candidate IRL757 has shown positive effects in several preclinical models of cognitive function, including improved motivation. This effect is believed to be associated with the drug candidate's unique ability to counteract disturbances in central nervous system nerve signaling proposed to underly apathy in several neurological conditions. Om Fas I-studienThe Phase I study consists of two parts and aims to document the safety, tolerability and pharmacokinetic properties of IRL757 in healthy subjects. In the first part of the study, single ascending doses of the drug candidate are administered (SAD) and in the second part, multiple ascending doses are given (MAD). In addition, the possible influence of concomitant food intake will be documented. For more information Kristina Torfgård, CEOPhone: +46 730 60 70 99E-mail: About IRL757 The drug candidate IRL757 is being developed as a treatment for apathy in Parkinson's disease and other neurological conditions. Apathy, a widespread and debilitating issue, affects over 20 million people in the U.S. and Europe alone without a currently available treatment. The prevalence is high, occurring in 1.1-4 million people (20-70 percent) being treated with Parkinson's in the eight major markets (China, EU5, Japan, and the US), and in 4.9-6.7 million people (43-59 percent) being treated for Alzheimer's disease in the ten major markets (Canada, China, EU5, Japan, South Korea, and the US). IRL757 has the potential to become the first treatment for apathy. The efficacy of IRL757 is thought to be linked to its unique ability to reverse disruption in cortical to sub-cortical nerve signalling, a key factor believed to contribute to apathy in neurological disorders. About IRLAB IRLAB discovers and develops a portfolio of transformative treatments for all stages of Parkinson's disease. The company originates from Nobel Laureate Prof Arvid Carlsson's research group and the discovery of a link between brain neurotransmitter disorders and brain diseases. Mesdopetam (IRL790), under development for treating levodopa-induced dyskinesias, has completed Phase IIb and is in preparation for Phase III. Pirepemat (IRL752), currently in Phase IIb, is being evaluated for its effect on balance and fall frequency in Parkinson's disease. IRL757, a compound being developed for the treatment of apathy in neurodegenerative disorders, is in Phase I. In addition, the company is developing two preclinical programs, IRL942 and IRL1117, towards Phase I studies. IRLAB's pipeline has been generated by the company's proprietary systems biology-based research platform Integrative Screening Process (ISP). Headquartered in Sweden, IRLAB is listed on Nasdaq Stockholm (IRLAB A). For more information, please visit . Attachments IRLAB reports positive results from the second part of a Phase I study with IRL757 SOURCE: IRLAB Therapeutics View the original press release on ACCESS Newswire
Yahoo
15-05-2025
- Business
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IRLAB to Present at BioStock Global Forum 2025
GOTHENBURG, SE / / May 15, 2025 / IRLAB Therapeutics (STO:IRLAB-A)(FRA:6IRA) - Gothenburg, Sweden, May 15, 2025 - IRLAB Therapeutics AB (Nasdaq Stockholm:IRLAB A), a company that discovers and develops new treatments for Parkinson's disease, today announces that CEO Kristina Torfgård will present IRLAB to potential partners and specialist investors at BioStock Global Forum 2025. The event will take place on May 20-21 in Lund, Sweden. Both Swedish and international investors, as well as prospective partners in the pharmaceutical industry, will participate in the meeting. This provides the company with an excellent opportunity to broaden its network and forge new connections. Kristina Torfgård, CEO, will present the company at 15:30 CEST on May 21. IRLAB's presentation will be filmed and made available afterward on Biostock's website and social media. More information about the meeting: For more information Kristina Torfgård, CEOPhone: +46 730 60 70 99E-mail: About IRLAB IRLAB discovers and develops a portfolio of transformative treatments for all stages of Parkinson's disease. The company originates from Nobel Laureate Prof Arvid Carlsson's research group and the discovery of a link between brain neurotransmitter disorders and brain diseases. Mesdopetam (IRL790), under development for treating levodopa-induced dyskinesias, has completed Phase IIb and is in preparation for Phase III. Pirepemat (IRL752), currently in Phase IIb, is being evaluated for its effect on balance and fall frequency in Parkinson's disease. IRL757, a compound being developed for the treatment of apathy in neurodegenerative disorders, is in Phase I. In addition, the company is developing two preclinical programs, IRL942 and IRL1117, towards Phase I studies. IRLAB's pipeline has been generated by the company's proprietary systems biology-based research platform Integrative Screening Process (ISP). Headquartered in Sweden, IRLAB is listed on Nasdaq Stockholm (IRLAB A). For more information, please visit . Attachments IRLAB to Present at BioStock Global Forum 2025 SOURCE: IRLAB Therapeutics View the original press release on ACCESS Newswire Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
13-05-2025
- Business
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IRLAB is Granted a Patent Expanding the Patent Protection for the Drug Candidate Mesdopetam in the US
GOTHENBURG, SE / / May 13, 2025 / IRLAB Therapeutics (STO:IRLAB-A)(FRA:6IRA) - Gothenburg, Sweden, May 13, 2025 - IRLAB Therapeutics AB (Nasdaq Stockholm: IRLAB A), a company discovering and developing novel treatments for Parkinson's disease, today announced that the company has been granted an additional 'composition of matter patent' in the US covering the salt of mesdopetam intended for use in the forthcoming pharmaceutical product and the process of its manufacture. The now granted patent expands the already strong patent protection for mesdopetam, which is IRLAB's most advanced drug candidate. "We are very pleased that the already strong patent protection for mesdopetam is being extended with a patent that protects a salt form of the active ingredient used in the clinical development of mesdopetam. The extended protection means that there is potential to extend the market exclusivity of the drug candidate all the way into the 2040s, which is incredibly positive for the value of mesdopetam," says Kristina Torfgård, CEO, IRLAB. Mesdopetam has a significant clinical potential to address the extensive unmet medical needs associated with Parkinson's disease. The drug candidate is intended to treat people with Parkinson's who develop levodopa-induced dyskinesias (LIDs), which affect more than 30 percent of all people living with the disease. This equates to more than 1.5 million affected individuals in the eight major markets worldwide. Mesdopetam has previously been granted a substance patent, in all major markets globally and the new patent provides added protection and extended exclusivity in most of the major markets such as the USA, Europe and Japan. The newly approved patent (US 12,275,694B2) covers the salt of mesdopetam which is used in ongoing clinical development and expires in the 2040s. In the event of a possible extension of the patent period (en. Patent Term Extension; PTE), the exclusivity could potentially extend well into the 2040s. IRLAB has recently also been granted a corresponding patent in Australia, where the exclusivity potentially extends well into the early 2040s. For more information Kristina Torfgård, CEOPhone: +46 730 60 70 99E-mail: Waters, EVP and Head of R&DPhone: +46 730 75 77 01E-mail: About IRLAB IRLAB discovers and develops a portfolio of transformative treatments for all stages of Parkinson's disease. The company originates from Nobel Laureate Prof Arvid Carlsson's research group and the discovery of a link between brain neurotransmitter disorders and brain diseases. Mesdopetam (IRL790), under development for treating levodopa-induced dyskinesias, has completed Phase IIb and is in preparation for Phase III. Pirepemat (IRL752), currently in Phase IIb, is being evaluated for its effect on balance and fall frequency in Parkinson's disease. IRL757, a compound being developed for the treatment of apathy in neurodegenerative disorders, is in Phase I. In addition, the company is developing two preclinical programs, IRL942 and IRL1117, towards Phase I studies. IRLAB's pipeline has been generated by the company's proprietary systems biology-based research platform Integrative Screening Process (ISP). Headquartered in Sweden, IRLAB is listed on Nasdaq Stockholm (IRLAB A). For more information, please visit . Attachments IRLAB is granted a patent expanding the patent protection for the drug candidate mesdopetam in the US SOURCE: IRLAB Therapeutics View the original press release on ACCESS Newswire Sign in to access your portfolio
Yahoo
12-05-2025
- Business
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Notice to the Annual General Meeting in IRLAB Therapeutics AB
GOTHENBURG, SE / / May 12, 2025 / IRLAB Therapeutics (STO:IRLAB-A)(FRA:6IRA) - IRLAB Therapeutics AB, reg. no. 556931-4692 ("IRLAB" or the "Company"), holds its Annual General Meeting on Wednesday 11 June 2205 at 17:00 (CEST) at MAQS Advokatbyrå's office on Masthamnsgatan 13, Gothenburg, Sweden. Entry and registration begin at 16:00 (CEST). For the full notice and supporting douments, please refer to the Swedish version of this pressrelease or visit Annual General Meeting 2025 - IRLAB . For more information Kristina Torfgård, VDPhone: +46 730 60 70 99E-mail: Viktor Siewertz, CFOPhone: +46 727 10 70 70E-mail: About IRLAB IRLAB discovers and develops a portfolio of transformative treatments for all stages of Parkinson's disease. The company originates from Nobel Laureate Prof Arvid Carlsson's research group and the discovery of a link between brain neurotransmitter disorders and brain diseases. Mesdopetam (IRL790), under development for treating levodopa-induced dyskinesias, has completed Phase IIb and is in preparation for Phase III. Pirepemat (IRL752), currently in Phase IIb, is being evaluated for its effect on balance and fall frequency in Parkinson's disease. IRL757, a compound being developed for the treatment of apathy in neurodegenerative disorders, is in Phase I. In addition, the company is developing two preclinical programs, IRL942 and IRL1117, towards Phase I studies. IRLAB's pipeline has been generated by the company's proprietary systems biology-based research platform Integrative Screening Process (ISP). Headquartered in Sweden, IRLAB is listed on Nasdaq Stockholm (IRLAB A). For more information, please visit . Attachments Notice to the Annual General Meeting in IRLAB Therapeutics AB SOURCE: IRLAB Therapeutics View the original press release on ACCESS Newswire Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
