Latest news with #Ins
Yahoo
30-04-2025
- Health
- Yahoo
Folia Health and Inspire are Partnering to Bring Personalized Home Health Observations to the Forefront of Patient Focused Drug Development Research
BOSTON, April 30, 2025 (GLOBE NEWSWIRE) -- Folia Health, the pioneer of patient-driven Home Reported Outcomes (HRO), has partnered with Inspire, the world's leading online health community and real-world data platform, to uniquely empower patients and caregivers with the opportunity to contribute a highly personalized form of structured at-home health observations data to accelerate patient-focused drug development research. In this collaboration, Folia and Inspire will focus on building longitudinal Real-World Evidence (RWE) Communities in some of the most complex and heterogeneous conditions to unlock insights that have been previously unattainable and unmeasurable in other data sources. Folia's HRO technology platform and user experience (UX) have been designed in collaboration with patients, caregivers, and clinicians to generate longitudinal insights that are dynamic to each individual. By allowing participants to self-select and define what's most meaningful to share about their lived disease experiences, we can now uncover aspects of diseases that have been the most difficult for researchers to understand and measure when developing novel therapies. 'We are thrilled to partner with Inspire to engage their member communities with our innovative, app-based solution that has been designed to bridge the gap between clinical care decision making and real-world evidence research. These RWE Communities within Inspire's member populations will provide a truly unique combination of real-world data that is required to answer the toughest questions in drug development and reimbursement today.' Nell Meosky Luo - CEO of Folia Health. As the world's largest online health community, Inspire is the go-to platform for patient and caregiver data, research and engagement. Inspire offers unique access to focused patient populations to support initiatives at every phase of development – from preclinical to post-approval marketing. Inspire is a trusted partner to over 100 patient advocacy organizations, and continues to identify opportunities that put patients and caregivers at the forefront of the most important questions in healthcare. 'At Inspire, we believe that empowering patients and caregivers to contribute their lived experiences is essential to driving meaningful research. By integrating Folia's innovative home-reported outcomes with our engaged health communities, we're unlocking new possibilities for real-world evidence generation that reflects the true patient journey—ultimately accelerating patient-focused drug development.' Brett Kleger - CEO of Inspire. Folia | Inspire - Revolutionizing Patient-Centered Real-World Evidence ResearchThis partnership enables the first large-scale digital approach to collecting the real-world lived experiences of patients outside of the clinic setting using Folia's HROs, and will directly measure patient-defined burden and the impact of various treatments on quality of life. These insights will be integrated with Inspire's member linked administrative claims data, EMR records, and AI enabled social media listening insights for the most robust patient-level insights available for patient-focused drug development research available today. The fully remote research model eliminates the need for clinic visits or research sites, while equipping patients with powerful insights to share with their care teams to ultimately receive more precise care. Unlike nearly every current research method today, HROs allow patients and caregivers to actively engage with their own study observations, gaining deeper insights into their personal symptom burden, treatment effects, and flare-up events that are commonly associated with complex diseases, while also seamlessly contributing their data for research. About Folia Health: Folia Health's home-reported outcomes (HROs) method and technology is pioneering the next generation of patient health data by transforming lived health experiences that occur at-home into valuable structured data insights to support research and personalized care. Through an innovative platform backed by expert analysis, we help life science partners develop effective therapies with demonstrated, real-world value for complex, chronic conditions. Folia's wealth of longitudinal data and proprietary analytics play a vital role in establishing a home-centered, data-driven healthcare ecosystem. Folia's platform is private, secure, and allows users to decide when and how their data is shared, while generating insightful trends, visualizations, and reports in the platform that allow them to receive more precise, data driven care. To explore the transformative potential of patient and caregiver knowledge, visit About Inspire: Founded in 2005, Inspire is the leading health community, connecting over 10 million patients and caregivers across 3,000 disease areas. Through its robust patient-centric platform, Inspire supports initiatives across the clinical development lifecycle—from preclinical research to post-market access—enabling life sciences organizations to capture real-world insights and accelerate medical advancements. For more information, visit Folia Health Contact:Connie Zhangconnie@ Inspire Contact:Jillian in to access your portfolio
Yahoo
29-03-2025
- Business
- Yahoo
With 55% ownership of the shares, Telekom Malaysia Berhad (KLSE:TM) is heavily dominated by institutional owners
Significantly high institutional ownership implies Telekom Malaysia Berhad's stock price is sensitive to their trading actions The top 4 shareholders own 59% of the company Analyst forecasts along with ownership data serve to give a strong idea about prospects for a business This technology could replace computers: discover the 20 stocks are working to make quantum computing a reality. A look at the shareholders of Telekom Malaysia Berhad (KLSE:TM) can tell us which group is most powerful. The group holding the most number of shares in the company, around 55% to be precise, is institutions. That is, the group stands to benefit the most if the stock rises (or lose the most if there is a downturn). Since institutional have access to huge amounts of capital, their market moves tend to receive a lot of scrutiny by retail or individual investors. Therefore, a good portion of institutional money invested in the company is usually a huge vote of confidence on its future. In the chart below, we zoom in on the different ownership groups of Telekom Malaysia Berhad. View our latest analysis for Telekom Malaysia Berhad Institutional investors commonly compare their own returns to the returns of a commonly followed index. So they generally do consider buying larger companies that are included in the relevant benchmark index. We can see that Telekom Malaysia Berhad does have institutional investors; and they hold a good portion of the company's stock. This implies the analysts working for those institutions have looked at the stock and they like it. But just like anyone else, they could be wrong. If multiple institutions change their view on a stock at the same time, you could see the share price drop fast. It's therefore worth looking at Telekom Malaysia Berhad's earnings history below. Of course, the future is what really matters. Investors should note that institutions actually own more than half the company, so they can collectively wield significant power. Telekom Malaysia Berhad is not owned by hedge funds. Looking at our data, we can see that the largest shareholder is Khazanah Nasional Berhad with 20% of shares outstanding. Meanwhile, the second and third largest shareholders, hold 17% and 12%, of the shares outstanding, respectively. On looking further, we found that 59% of the shares are owned by the top 4 shareholders. In other words, these shareholders have a meaningful say in the decisions of the company. While it makes sense to study institutional ownership data for a company, it also makes sense to study analyst sentiments to know which way the wind is blowing. There are plenty of analysts covering the stock, so it might be worth seeing what they are forecasting, too. While the precise definition of an insider can be subjective, almost everyone considers board members to be insiders. Management ultimately answers to the board. However, it is not uncommon for managers to be executive board members, especially if they are a founder or the CEO. Insider ownership is positive when it signals leadership are thinking like the true owners of the company. However, high insider ownership can also give immense power to a small group within the company. This can be negative in some circumstances. Our most recent data indicates that insiders own less than 1% of Telekom Malaysia Berhad. It is a pretty big company, so it would be possible for board members to own a meaningful interest in the company, without owning much of a proportional interest. In this case, they own around RM2.2m worth of shares (at current prices). It is good to see board members owning shares, but it might be worth checking if those insiders have been buying. With a 25% ownership, the general public, mostly comprising of individual investors, have some degree of sway over Telekom Malaysia Berhad. While this group can't necessarily call the shots, it can certainly have a real influence on how the company is run. I find it very interesting to look at who exactly owns a company. But to truly gain insight, we need to consider other information, too. Be aware that Telekom Malaysia Berhad is showing 2 warning signs in our investment analysis , and 1 of those makes us a bit uncomfortable... If you are like me, you may want to think about whether this company will grow or shrink. Luckily, you can check this free report showing analyst forecasts for its future. NB: Figures in this article are calculated using data from the last twelve months, which refer to the 12-month period ending on the last date of the month the financial statement is dated. This may not be consistent with full year annual report figures. Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.
The Hill
24-03-2025
- Politics
- The Hill
Trump's gambit of using Putin against Iran will fail
President Trump thinks he has found an unlikely mediator to tame Iran's nuclear ambitions: Vladimir Putin. Ending the Ukraine war to rebuild bridges with Moscow and leveraging Russia's influence to pressure Tehran — on paper, it might seem bold, even strategic. But it is detached from reality. Putin gains nothing by threatening his Iranian allies. In fact, Moscow and Tehran's strategic partnership has grown stronger precisely because of shared opposition to American influence. Trump is wrong to assume that Russia can be manipulated into serving U.S. interests, ignoring the deepening alignment between the two authoritarian powers. By mistaking rivalry for leverage, Trump risks not only empowering Putin but also destabilizing the Middle East further, ensuring his diplomatic strategy ends in failure. Having lost more than 800,000 soldiers, suffered cumulative GDP losses exceeding $500 billion and moving towards a 'decade-long recession' with $300 billion of Russian foreign reserves frozen due to sanctions, Putin already feels the weight of the invasion he launched in 2022. The war is now more than three years long. He wants an exit, provided it occurs on his terms. Trump sees an opportunity: end the war, ease sanctions and use Putin to pressure Iran. In a February phone conversation, Putin agreed to assist Trump in brokering U.S.-Iran nuclear negotiations, a matter further discussed when Russian and American diplomats met in Riyadh. Trump has already taken unilateral actions against Iran by reimposing 'maximum pressure' sanctions. At the same time, he has signaled openness to diplomacy by sending a letter to Supreme Leader Ali Khamenei. However, the fundamental flaw in Trump's approach is outsourcing U.S. strategic interests to Putin, a leader who thrives on geopolitical instability. Putin has no incentive to push Iran toward an agreement that benefits Washington, especially now that Tehran has become Moscow's crucial military and economic ally. Since 2022, Russia and Iran have formed a deep strategic partnership. Iran has supplied Russia with thousands of Shahed-136 drones, used in devastating attacks on Ukraine, while Moscow has provided Iran with air-defense systems, missile technology and diplomatic cover at the U.N. In January, Putin signed a 20-year strategic cooperation agreement with Iran, ensuring long-term military, economic and intelligence collaboration. Russia has also helped Iran evade Western sanctions, further strengthening their alliance. Given this reality, why would Putin pressure an ally that actively helps him counterbalance American influence? The answer is simple: He won't. Even if Putin were willing to push Iran toward negotiations, Tehran has made it clear it won't fold under pressure. When Trump sent a letter to Khamenei in March, Iran immediately dismissed it and vowed not to negotiate under American threats. Iran has no reason to trust Washington after Trump abandoned the 2015 nuclear deal despite Tehran's compliance. Instead of slowing its nuclear program, Iran is accelerating it. The International Atomic Energy Agency recently confirmed that Iran is enriching uranium close to weapons-grade levels, signaling a dangerous escalation. Furthermore, Putin won't mediate. Instead, he will use Iran's nuclear program to extract American concessions. Moscow has historically played both sides, publicly supporting diplomacy while secretly assisting Iran. Putin has no intention of stopping Iran's nuclear program, only of using it to extract concessions from Washington. Trump's reliance on Putin as a mediator is also creating space for China to expand its influence. In March, China hosted trilateral talks with Moscow and Tehran, reinforcing its role as Iran's primary economic and diplomatic backer. But China's role goes beyond mere economic support. A nuclear-capable Iran serves Beijing's broader strategic interests by keeping the U.S. entangled in Middle Eastern conflicts. Every moment Washington spends countering Tehran is a moment diverted from countering China's rise in the Indo-Pacific. At the same time, China's continued oil purchases provide Iran with a financial lifeline, weakening the impact of U.S. sanctions and reducing Trump's leverage. Beijing's strategy is pragmatic. China benefits from an Iran strong enough to resist America pressure but not so unstable that it triggers a full-scale regional war. By funding Iran while advocating for diplomacy, China positions itself as the ultimate power broker in the region, while ensuring that the U.S. remains distracted. Trump's strategy rests on a fantasy: that Putin would ever act in Washington's interests over his own. In reality, Russia benefits from keeping the Iran crisis unresolved, using it as a bargaining chip to extract concessions from the U.S. Meanwhile, Iran has no reason to trust Trump's outreach, having been burned when he abandoned the 2015 nuclear deal. Tehran is accelerating its nuclear program, not slowing it down, proving that threats and sanctions alone won't force it to the table. Rather than outsourcing U.S. foreign policy to Putin, Washington should reengage with its European and regional allies to build a unified approach toward Iran. A combination of targeted economic incentives, security guarantees for regional partners and multilateral diplomacy, rather than erratic deal-making with Moscow, offers a more realistic path to containing Iran's nuclear ambitions. The Iran nuclear deal's collapse has shown that unilateral pressure tactics fail when they lack international coordination. A pragmatic U.S. strategy should focus on strengthening diplomatic leverage through coalitions, not wishful thinking about Putin's goodwill. If Trump's Putin gambit continues, it will leave him two bad choices: a nuclear-armed Iran or war.
CNN
20-03-2025
- CNN
New defense filings shed light on communications by roommates of killed University of Idaho students before 911 call
New court filings in the University of Idaho case continue to fill out the timeline of communications by two surviving roommates in the hours between four other students were killed in their house and when they called 911. The brutal killings of the four University of Idaho students – Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin – took place at an off-campus residence in Moscow in 2022. Bryan Kohberger is charged with their murders, has pleaded not guilty and faces the death penalty in a trial that is set to begin in August. In a court filing released Wednesday, defense attorneys for Kohberger took issue with what they say is the state prosecutors' selective use of phone records for surviving roommates Dylan Mortensen and Bethany Funke on the early morning of November 13, 2022. They advocated for the judge to prohibit prosecutors from showing the prosecutor's selection of the roommates' messages to the jury – or for the judge to allow more phone records to be admitted at trial so the jury can see what they call a fuller picture of what transpired. CNN previously reported that phone records show Mortensen and Funke exchanged panicked text messages when they couldn't reach their other housemates around the time investigators believe the killings occurred, between 4 a.m. and 4:30 a.m. Mortensen texted Funke at 4:22, saying 'No one is answering.' Funke says, 'Ya dude wtf.' Mortensen then texted Funke that she saw what looked like a masked man in their house, saying, 'I'm freaking out.' Funke later texted Mortensen: 'Come to my room,' and 'run.' The new defense filing says Funke accessed Snapchat and Instagram shortly after the text exchange and called her parents hours later. Records previously released in a motion by prosecutors suggested Mortensen renewed her efforts to reach the others in the house at about 10:23 a.m. only after 'waking up and realizing that she had not heard from her roommates.' But Kohberger's attorneys now say Mortensen joined Funke in her room and their phone activity was only dark for about three hours. According to the defense filing, Mortensen's phone records show that she was awake earlier than prosecutors claim she woke up. The defense filing reveals a string of phone activity for Mortensen and Funke not previously made public. Funke and Mortensen, identified by their initials in the court documents, were both using their phones by around 8 a.m., the new defense filing claims Funke first called her dad's phone at 7:30 a.m. The defense's motion details the following call activity and social media access by the roommates, picking up hours after their text exchanges and Funke last accessing Instagram at 4:37 a.m.: 7:30 BF calls dad 8:00 BF calls dad 8:00 BF calls another number 8:01 BF calls home 8:02 BF calls mom 8:09 dad calls BF 8:05:43 – 10:00:45 DM on Instagram 8:41-8:42 BF takes photos 9:04:36 mom texts BF 10:00:56 – 10:01:40 DM messages, incoming and outgoing (snapchat) 10:01:53 – 10:03:05 DM on Instagram 10:03:30 – 10:04:02 DM on Indeed 10:04:54 – 10:23:02 DM messages, incoming and outgoing (snapchat) In the motion, Kohberger's attorneys dispute the prosecution's claims that Mortensen woke up to realize her roommates hadn't responded to her texts overnight. Mortensen tried again to reach Goncalves and Mogen starting at 10:23 a.m., asking them if they were awake: 'R u up??' The new defense filing says Mortensen used Snapchat, Instagram and TikTok and texted her dad hours before she reached out to Mogen and Goncalves again. 10:23:23 DM text MM 10:24:01 – 10:25:04 DM on Instagram 10:30:18 – 10:45:43 DM messages, incoming and outgoing (snapchat) 11:21:53 JM texts BF 10:56:49 – 11:29:08 DM on Instagram and messages on snapchat 11:29:27 DM text KG 11:29:41 – 11:32:45 DM on Instagram and messaging on snapchat 11:35:36 DM on Yik Yak 11:36:07 DM on Tik Tok 11:37:36 DM messages (snapchat) 11:39:09 -11:40:14 DM and dad text 11:49 BF calls JM 11:50:55 JM text DM 11:44:06 – 11:50:38 DM on Instagram 11:50:58 DM calls EA 11:51:01 JM texts DM 11 :54 :57-11 :55 :01 JM texts BF 3 texts 11:54:39 – 11:57:01 DM on Instagram Funke eventually called 911 at 11:56 a.m. to report Kernodle unconscious at the residence, records show, and two other friends could be heard with them on the call. A transcript of the surviving roommates' 911 call was also released with a filing earlier this month. The transcript shows the chaos as Mortensen and Funke pass the phone between them answering the dispatcher in fragmented responses. The transcript does not identify the speakers by name but shows another unnamed friend with them also spoke to the dispatcher. Heavy breathing and crying can be heard throughout the call. CNN obtained an audio recording of the call after the transcript was released. Prosecutors have indicated they expect both surviving roommates to testify at trial and want to use their text messages to illustrate the timeline of the night. Defense attorney Anne Taylor has pointed to what she described as inconsistencies in law enforcement interviews with Mortensen and Funke. In the latest defense filing, Kohberger's attorney calls into question why the surviving roommates didn't call 911 sooner. 'Despite her stated fear of leaving her room she does so and joins BF downstairs. To get to BF's bedroom DM passed the front door of the residence. BF was steps from the front door. Neither of them left the house. Neither of them called friends, family or law enforcement for help,' the filing claims. The defense brief was among dozens of court filings released Wednesday as the parties make their cases to the judge about what should and shouldn't be admissible evidence at trial. In another defense filing released in the tranche, Kohberger's attorneys say, 'Many alternate perpetrators can be connected to the crime,' and they have evidence they want to show the court. Prosecutors plan to call law enforcement witnesses to testify about a test run they conducted to show that it was possible to commit four homicides in a time frame of only minutes including time to walk to and from a car and remove blood-covered clothes, a defense filing says. Kohberger's attorneys say they need an expert to testify about his developmental coordination disorder to show the jury he was not physically capable of committing the crime that they argue required such speed and coordination.
CNN
20-03-2025
- CNN
New defense filings shed light on communications by roommates of killed University of Idaho students before 911 call
New court filings in the University of Idaho case continue to fill out the timeline of communications by two surviving roommates in the hours between four other students were killed in their house and when they called 911. The brutal killings of the four University of Idaho students – Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin – took place at an off-campus residence in Moscow in 2022. Bryan Kohberger is charged with their murders, has pleaded not guilty and faces the death penalty in a trial that is set to begin in August. In a court filing released Wednesday, defense attorneys for Kohberger took issue with what they say is the state prosecutors' selective use of phone records for surviving roommates Dylan Mortensen and Bethany Funke on the early morning of November 13, 2022. They advocated for the judge to prohibit prosecutors from showing the prosecutor's selection of the roommates' messages to the jury – or for the judge to allow more phone records to be admitted at trial so the jury can see what they call a fuller picture of what transpired. CNN previously reported that phone records show Mortensen and Funke exchanged panicked text messages when they couldn't reach their other housemates around the time investigators believe the killings occurred, between 4 a.m. and 4:30 a.m. Mortensen texted Funke at 4:22, saying 'No one is answering.' Funke says, 'Ya dude wtf.' Mortensen then texted Funke that she saw what looked like a masked man in their house, saying, 'I'm freaking out.' Funke later texted Mortensen: 'Come to my room,' and 'run.' The new defense filing says Funke accessed Snapchat and Instagram shortly after the text exchange and called her parents hours later. Records previously released in a motion by prosecutors suggested Mortensen renewed her efforts to reach the others in the house at about 10:23 a.m. only after 'waking up and realizing that she had not heard from her roommates.' But Kohberger's attorneys now say Mortensen joined Funke in her room and their phone activity was only dark for about three hours. According to the defense filing, Mortensen's phone records show that she was awake earlier than prosecutors claim she woke up. The defense filing reveals a string of phone activity for Mortensen and Funke not previously made public. Funke and Mortensen, identified by their initials in the court documents, were both using their phones by around 8 a.m., the new defense filing claims Funke first called her dad's phone at 7:30 a.m. The defense's motion details the following call activity and social media access by the roommates, picking up hours after their text exchanges and Funke last accessing Instagram at 4:37 a.m.: 7:30 BF calls dad 8:00 BF calls dad 8:00 BF calls another number 8:01 BF calls home 8:02 BF calls mom 8:09 dad calls BF 8:05:43 – 10:00:45 DM on Instagram 8:41-8:42 BF takes photos 9:04:36 mom texts BF 10:00:56 – 10:01:40 DM messages, incoming and outgoing (snapchat) 10:01:53 – 10:03:05 DM on Instagram 10:03:30 – 10:04:02 DM on Indeed 10:04:54 – 10:23:02 DM messages, incoming and outgoing (snapchat) In the motion, Kohberger's attorneys dispute the prosecution's claims that Mortensen woke up to realize her roommates hadn't responded to her texts overnight. Mortensen tried again to reach Goncalves and Mogen starting at 10:23 a.m., asking them if they were awake: 'R u up??' The new defense filing says Mortensen used Snapchat, Instagram and TikTok and texted her dad hours before she reached out to Mogen and Goncalves again. 10:23:23 DM text MM 10:24:01 – 10:25:04 DM on Instagram 10:30:18 – 10:45:43 DM messages, incoming and outgoing (snapchat) 11:21:53 JM texts BF 10:56:49 – 11:29:08 DM on Instagram and messages on snapchat 11:29:27 DM text KG 11:29:41 – 11:32:45 DM on Instagram and messaging on snapchat 11:35:36 DM on Yik Yak 11:36:07 DM on Tik Tok 11:37:36 DM messages (snapchat) 11:39:09 -11:40:14 DM and dad text 11:49 BF calls JM 11:50:55 JM text DM 11:44:06 – 11:50:38 DM on Instagram 11:50:58 DM calls EA 11:51:01 JM texts DM 11 :54 :57-11 :55 :01 JM texts BF 3 texts 11:54:39 – 11:57:01 DM on Instagram Funke eventually called 911 at 11:56 a.m. to report Kernodle unconscious at the residence, records show, and two other friends could be heard with them on the call. A transcript of the surviving roommates' 911 call was also released with a filing earlier this month. The transcript shows the chaos as Mortensen and Funke pass the phone between them answering the dispatcher in fragmented responses. The transcript does not identify the speakers by name but shows another unnamed friend with them also spoke to the dispatcher. Heavy breathing and crying can be heard throughout the call. CNN obtained an audio recording of the call after the transcript was released. Prosecutors have indicated they expect both surviving roommates to testify at trial and want to use their text messages to illustrate the timeline of the night. Defense attorney Anne Taylor has pointed to what she described as inconsistencies in law enforcement interviews with Mortensen and Funke. In the latest defense filing, Kohberger's attorney calls into question why the surviving roommates didn't call 911 sooner. 'Despite her stated fear of leaving her room she does so and joins BF downstairs. To get to BF's bedroom DM passed the front door of the residence. BF was steps from the front door. Neither of them left the house. Neither of them called friends, family or law enforcement for help,' the filing claims. The defense brief was among dozens of court filings released Wednesday as the parties make their cases to the judge about what should and shouldn't be admissible evidence at trial. In another defense filing released in the tranche, Kohberger's attorneys say, 'Many alternate perpetrators can be connected to the crime,' and they have evidence they want to show the court. Prosecutors plan to call law enforcement witnesses to testify about a test run they conducted to show that it was possible to commit four homicides in a time frame of only minutes including time to walk to and from a car and remove blood-covered clothes, a defense filing says. Kohberger's attorneys say they need an expert to testify about his developmental coordination disorder to show the jury he was not physically capable of committing the crime that they argue required such speed and coordination.
