Latest news with #KidneyVaultPortableRenalPerfusionSystem
Business Wire
29-05-2025
- Health
- Business Wire
UCI Health Partner with Sierra Donor Services to Expand Kidney Transplant Opportunities Utilizing Paragonix KidneyVault Preservation Technology
WALTHAM, Mass.--(BUSINESS WIRE)-- Paragonix Technologies, a pioneer in organ transplant technologies and organ procurement services, announced today a groundbreaking initiative with Sierra Donor Services and UCI Health to place high-risk donor kidneys, expanding transplant opportunities for patients in need. , a nonprofit organ procurement organization (OPO) serving more than 2.8 million people across 13 counties in Northern California and Nevada, is leveraging this collaboration to successfully place kidneys that were previously deemed high risk due to donor complications, geographic limitations, and other logistical considerations. Utilizing Paragonix's latest innovation—the KidneyVault Portable Renal Perfusion System —Sierra Donor Services has facilitated the transplantation of complex donor kidneys that had initially been declined due to factors such as donor age, cause of death, and underlying medical conditions. Through this technology, UCI Health has been able to transplant these organs successfully, demonstrating the transformative potential of advanced organ preservation in expanding the donor pool. The cutting-edge preservation system aims to combat key transplantation challenges by ensuring superior organ protection during transport and providing real-time monitoring of organ conditions and location. UCI Health, one of California's largest academic health systems, is the clinical enterprise of the University of California, Irvine and one of the fastest growing kidney transplant centers on the west coast. UCI Health is at the forefront of transplant innovation, seeking new opportunities and technologies to both improve access to donor organs and post-transplant outcomes. The lifesaving initiative is playing a critical role in addressing California's organ shortage by enabling the safe and effective utilization of kidneys that may have otherwise been potentially discarded. 'Currently, nearly 20,000 Californians are on the waiting list for a transplant, with 85% of them in need of a kidney. Last year over 9,000 kidneys recovered for transplant were ultimately unable to be used for a life saving transplant,' said Donna Smith, Chief Clinical Officer at Sierra Donor Services. 'The portable renal perfusion technology provided by KidneyVault gives us greater flexibility to place these much-needed organs, offering a second chance at life to patients who might not have otherwise received one.' Dr. Robert R. Redfield, Chief of Transplantation at UCI Health, emphasized the importance of this innovative preservation system in expanding transplant opportunities. 'UCI Health is proud to have the oldest and largest kidney transplant program in Orange County, with survival outcomes exceeding the national average,' said Dr. Redfield. 'This technological improvement allows transplant centers like ours to consider more complex organs, as donations that must travel greater distances can now be perfused throughout the entire transplant journey.' President of Paragonix Technologies, Dr. Lisa Anderson, PhD, echoed this sentiment, highlighting the company's commitment to honoring the gift of organ donation. 'Every organ donation is an incredible gift, and we believe it should be treated as such every single time,' said Dr. Anderson. 'With the KidneyVault Portable Renal Perfusion System, OPOs and transplant centers can confidently offer this life-saving gift to more patients by utilizing organs that previously would have gone unused.' For more information about Paragonix Technologies, please visit About Sierra Donor Services Sierra Donor Services (SDS) serves nearly three million people in Northern California and Northern Nevada. We are an exceptional team of professionals dedicated to saving and improving lives by connecting organ and tissue donation to the patients who need them. We strive to extend the reach of each generous donor's gift to those who are always profoundly grateful for them. For more information, visit About Paragonix Technologies Paragonix Technologies is a leading developer, manufacturer, and service provider in the organ transplant industry, establishing a novel approach to organ preservation. A Getinge company, Paragonix Technologies provides Advanced Organ Preservation ('AOP') devices that safeguard donor organs during the journey between donor and recipient patients. Our FDA-cleared and CE-marked devices incorporate clinically proven and medically trusted cold preservation techniques that allow unprecedented physical and thermal protection to the organ during transit. All Paragonix AOP devices are natively integrated with our novel digital app, delivering real-time organ tracking data and monitoring logistics for transplant teams seeking a secure and centralized solution. For more information, visit
Yahoo
28-01-2025
- Health
- Yahoo
Paragonix Announces World's First-In-Human Use of KidneyVault Renal Perfusion System
Novel portable hypothermic perfusion technology facilitates the preservation and transport of perfused donor kidneys throughout journey from donor to recipient WALTHAM, Mass., January 28, 2025--(BUSINESS WIRE)--Paragonix Technologies, a pioneer in organ transplant technologies and organ procurement services, announced today the completion of the world's first-in-human cases utilizing its FDA-cleared KidneyVault™ Portable Renal Perfusion System, marking a new chapter in kidney transplant preservation. These landmark cases included the successful transport of four donor kidneys to four separate medical institutions across the nation in a 24-hour period last December. The successful transplants were made possible through the support of leading OPOs (organ procurement organizations), including LifeGift of Houston, Texas. The KidneyVault Portable Renal Perfusion System received FDA clearance in October of 2024. The lightweight device is designed for convenient end-to-end hypothermic perfusion, offering new levels of standardization that aligns with kidney allocation workflow of all involved parties. OPOs and transplant centers can remotely monitor the device in real-time with a data-driven dashboard that shares perfusion parameters, temperature conditions, and other critical data at all times. The combination of portable perfusion technology and real-time data insights offer OPOs and transplant centers a comprehensive solution currently unavailable on the market. OPOs like LifeGift leverage advanced technologies such as the KidneyVault System to improve post-transplant outcomes and increase national access to the limited pool of available donations. Kidney donation represents a striking demand of nearly 90,000 total individuals listed in need of a donation – 86% of the 2024 transplant waiting list. At the end of November 2024, just over 25,000 kidney transplantations were able to be performed. "Hypothermic perfusion increases the availability of high-quality donor kidneys nationwide," said Yolanda Becker, MD, Vice President and Chief Medical Officer at LifeGift. "However, historically, it was not always feasible to deliver every kidney on pump due to the distances traveled increasing cold ischemic times. LifeGift is now at the forefront of portable perfusion technologies that allow us to transport kidneys greater distances, by ground or commercial air, using a single controlled device from end-to-end. This hands-off solution provides the flexibility to deliver a kidney on pump to transplant centers." The national kidney allocation policy was revised in recent years to enable broader organ distribution strategies and increase the overall volume of transplant offers. Placement efforts have increased dramatically for each kidney, resulting in more complex logistics and extended transport times in which the kidney remains outside of the body, a concept known as cold ischemia time. Notably, the clinical community has come to rely on hypothermic machine perfusion devices to compensate for longer cold ischemia times by pumping a perfusate solution through the kidney to sustain viability in a controlled environment. "LifeGift is proud to be among the first to adopt this innovative technology," said Kevin A. Myer, MSHA, LifeGift President & CEO. "LifeGift is committed to clinical research and new technologies that will help save lives today and in the future. The device allows us to provide our transplant center partners with recovered kidneys that have been monitored throughout the journey, regardless of the transportation mode. The portability of the system will facilitate broader sharing of machine-perfused kidneys and will result in greater use of recovered kidneys for transplant." The successful first-in-human use of the KidneyVault System marks a major milestone in Paragonix Technologies' mission to transform the standard of care in transplantation. Notably, Paragonix now offers advanced preservation technologies across all solid organ transplantation – a world first. "We are fully committed to ensuring every patient has the best possible chance at life," said Lisa Anderson, PhD, President of Paragonix Technologies. "This achievement highlights the potential of this one-of-a kind portable perfusion technology and sets a new standard for safety, reliability, and efficiency." For more information about Paragonix Advanced Organ Preservation devices, please visit About LifeGift LifeGift is a nonprofit, 501(c)(3) health services organization. As the organ procurement organization (OPO) for North, Southeast and West Texas, we partner with more than 200 hospitals across 109 counties to save and heal lives. LifeGift is a founding member of Donate Life Texas, the organization that manages the organ, eye and tissue donor registry. For more information, please visit About Paragonix Technologies Paragonix Technologies is a leading developer, manufacturer, and service provider in the organ transplant industry, establishing a novel approach to organ preservation. Paragonix Technologies provides Advanced Organ Preservation ("AOP") devices that safeguard donor organs during the journey between donor and recipient patients. Our FDA-cleared and CE-marked devices incorporate clinically proven and medically trusted cold preservation techniques that allow unprecedented physical and thermal protection to the organ during transit. All Paragonix AOP devices are natively integrated with our novel digital app, delivering real-time organ tracking data and monitoring logistics for transplant teams seeking a secure and centralized solution. For more information, visit Follow us on Twitter: @ParagonixSherpa Connect with us on LinkedIn: Paragonix Technologies Like Us on Facebook: Paragonix Technologies View source version on Contacts Paragonix Media Contact: Adam Lafreniere, Vice President, Marketingmarketing@ Sign in to access your portfolio
