Latest news with #KyasanurForestDisease


News18
6 days ago
- Health
- News18
Dengue To Nipah: NIV Developing Vaccines For These Deadly Viruses In India
Last Updated: With Nakshatra supercomputer at NIV Pune, virus mutations can be tracked in real time, speeding up vaccine development and enabling swift national response The National Institute of Virology's (NIV) fight against deadly viruses is gaining momentum far beyond dengue. While India's first indigenous dengue vaccine has reached the final phase of human trials—an important breakthrough in tackling the mosquito-borne illness—NIV is also developing vaccines and diagnostic tools for several other high-risk viruses, aiming to reduce the country's reliance on imported technology and boost epidemic preparedness. The Kyasanur Forest Disease (KFD) virus, prevalent in Karnataka and surrounding forests, causes a severe fever, and its vaccine is now in an advanced stage. Chandipura Virus The Chandipura virus, which induces high fever in children, is also being targeted by NIV for a vaccine. Nipah Virus India is developing a vaccine for the highly lethal Nipah virus using monoclonal antibody technology. CCHF Virus The zoonotic Crimean-Congo Haemorrhagic Fever (CCHF) virus is also under surveillance by the NIV, where work on a vaccine and diagnostic kit is already underway. These advancements signify India's growing self-reliance in addressing biological threats. With Nakshatra in place, virus mutations can be tracked in real time, accelerating vaccine development and enabling faster national response during outbreaks. The arrival of this supercomputer is being hailed as a revolutionary step in India's virology efforts. Eradicating Dengue India's first indigenous dengue vaccine could mark a turning point in the country's decades-long battle against the disease. The vaccine has shown promise against all four serotypes of the dengue virus, thanks to modern biotechnology advances in the NIV labs. If the final phase of trials is successful, India will soon have its first homegrown and safe dengue vaccine. Get breaking news, in-depth analysis, and expert perspectives on everything from politics to crime and society. Stay informed with the latest India news only on News18. Download the News18 App to stay updated! First Published:


Time of India
12-06-2025
- Health
- Time of India
Centre joins German govt to study, curb KFD in Goa
Panaji: Kyasanur Forest Disease (KFD), also known as monkey disease, emerged in Goa in March 2015. The state reported one death in 2015 and three deaths in 2016. The health department controlled the disease after over 460 cases through various measures. Tired of too many ads? go ad free now Currently, regions in Goa, along with Madhya Pradesh and Karnataka, are included in the central govt's pilot project on KFD. The pilot project aims to create awareness in villages located in the foothills of the Western Ghats, particularly in parts of Sattari, Goa. Additionally, the project will examine the relationship between altered biodiversity and KFD for the first time. The six-month study's findings will assist the Centre in preventing similar disease outbreaks nationwide. Pradip Sarmokadam, member secretary of the Goa State Biodiversity Board, said the increase in KFD cases in Goa occurred during the cashew plucking season. He noted that ticks on certain plants contribute to the disease's spread. 'It will be seen under the project if some of these plants that are made home by the ticks can be eliminated or reduced from the environment in the villagers of Sattari at the foothills of the Western Ghats, where there is history of KFD,' Sarmokadam said. The state established a committee on zoonosis for the first time. Sarmokadam added, 'The project is being taken up under govt of India's One Health Mission and GIZ of the German govt. It will aim to eliminate the roots of such diseases, ensure better preparedness to tackle them, and mobilise local people and biodiversity management committees to bring in behavioural changes in the locals through awareness etc to prevent KFD.


Time of India
21-04-2025
- Health
- Time of India
In Karnataka, sudden deaths from KyasanurForest Disease raise concerns
Bengaluru: The number of Kyasanur Forest Disease (KFD) cases in Karnataka rose to 153, with four deaths reported so far this season. What concerns health authorities is not just the rise in infections, but the nature of the fatalities — all four patients initially showed signs of recovery before sudden deterioration in their conditions. Medical investigations revealed that each case of death involved a different complication, leaving experts unable to establish a consistent clinical pattern. This unpredictability is making it harder for doctors to anticipate disease progression and adapt treatment protocols effectively. "All the deaths occurred under close monitoring by govt-appointed doctors, and each case was investigated thoroughly," said Dr Ansar Ahmed, project director, Integrated Disease Surveillance Programme (IDSP). "These deaths were unexpected, and in many ways, unprecedented. That's why we believe there's an urgent need for more research and surveillance — both by ICMR and other govt institutions — as well as through collaboration with private research bodies and NGOs." Dr Ahmed noted that KFD alone wasn't the direct cause in any of the fatalities. "I've personally gone through each case in detail. What we found is that every death had a different cause or underlying condition. In many instances, it was complications after KFD or pre-existing comorbidities that led to the fatal outcome. KFD, when combined with other health issues, can lead to unpredictable and rapid deterioration — and that's exactly what we've seen." Chikmagalur and Shivamogga districts saw two deaths each of KFD patients. The most recent death occurred on April 17. An eight-year-old boy from Thirthahalli was under close monitoring by health officials for 12 days and was taken off the ventilator when his vitals seemed stable. However, he died the night his condition improved. "Some of the recent deaths we've seen were entirely preventable," Harsh Gupta, principal secretary, health and family welfare department, said, adding: "In one case, the patient was on a ventilator with stable vitals, yet we lost them. It was deeply unfortunate. In other cases, multiple comorbidities made recovery extremely difficult. These were high-risk patients, and despite our best efforts, not all could be saved." He added that the govt took proactive steps early in the season to strengthen KFD response systems. "We enhanced our alert and reporting mechanisms and ensured that no patient would be denied treatment due to financial constraints. The govt is covering the costs of care, including management of post-infection complications. This has helped us offer timely treatment and prevent more deaths." However, officials admit that the sudden nature of recent fatalities exposed certain gaps in response and understanding of the disease. "While the situation looks better than last year in terms of overall caseload, the unexpected deaths have caught us off guard," Gupta said. "We're now coordinating with tertiary hospitals to conduct deeper clinical analysis. KFD doesn't present the same way every year — its symptoms, warning signs, and progression patterns seem to change. That means our treatment protocols must evolve too." — **BOX 2: Districtwise cases since Jan 1 Chikamagalur: 83 Shivamogga: 65 Uttara Kannada: 6 Source: Health & family welfare dept