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University of Delaware Study Identifies Optimal Formulation of ZIVO's Active Ingredients for Further Testing to Mitigate Avian Influenza in Poultry
University of Delaware Study Identifies Optimal Formulation of ZIVO's Active Ingredients for Further Testing to Mitigate Avian Influenza in Poultry

Business Wire

time06-05-2025

  • Health
  • Business Wire

University of Delaware Study Identifies Optimal Formulation of ZIVO's Active Ingredients for Further Testing to Mitigate Avian Influenza in Poultry

BUSINESS WIRE)-- ZIVO Bioscience, Inc. (OTCQB: ZIVO), a pioneering biotech/agtech R&D company dedicated to developing therapeutic, medicinal and nutritional product candidates derived from proprietary algal cultures, today announced positive results from its second collaborative study with the University of Delaware evaluating the efficacy of several formulations of ZIVO's proprietary active ingredients in mitigating the spread of Low Pathogenicity Avian Influenza (LPAI) virus among poultry. Building upon the outcomes of the initial study, this second study aimed to assess and compare the performance of three different ZIVO formulations in both directly challenged and contact-exposed birds. The study affirmed earlier observations that ZIVO's active ingredients may positively influence LPAI transmission dynamics, while identifying the optimal formulation for further testing. In the first arm of the study, which involved birds receiving a direct challenge with LPAI, modest positive trends were observed in viral shedding reduction among ZIVO-treated groups compared with untreated controls. While these differences did not reach statistical significance, the findings suggest potential for ZIVO's formulations to lessen disease severity. The second arm focused on the transmission of the virus from infected birds to naïve birds. Notably, the formulation consisting of a blend of four distinct algal-derived materials demonstrated a slower and less efficient spread of the virus. One bird treated with this combination showed no signs of infection post-exposure, indicating potential protective effects. Brian Ladman, PhD, Principal Investigator at the University of Delaware's Department of Animal and Food Sciences, commented, "Any positive trend observed in these early-stage studies is very encouraging. Delaying transmission, even by a few days, can provide significant benefits to poultry producers by allowing more time to manage high risk or at-risk flocks effectively." "These findings resulting from rigorous testing at the University of Delaware reinforce our commitment to developing sustainable, non-antibiotic solutions for the poultry industry. The insights gained from this study show encouraging trends and identifying a superior formulation will be instrumental in guiding our future research and product optimization efforts. Given the potential impact ZIVO's product can have on mitigating avian influenza, a widespread issue in the nation's large poultry industry, we submitted a funding request to the State of Michigan for $5.5 million to further our research. Additionally, we are applying for a portion of the previously announced $100 million Avian Influenza Poultry Innovation Grand Challenge from the USDA," said John Payne, Chairman and CEO of ZIVO Bioscience. ZIVO Bioscience remains dedicated to advancing its pipeline of algal-derived compounds aimed at enhancing poultry health and productivity. The company plans to continue its collaboration with the University of Delaware to further explore and refine these interventions, including a larger scale project focused on a single formulation in order to determine the reproducibility of the observations from the first two studies. About ZIVO Bioscience ZIVO Bioscience, Inc. is a research and development company with an intellectual property portfolio comprised of proprietary algal and bacterial strains, biologically active molecules and complexes, production techniques, cultivation techniques and patented or patent-pending inventions for applications in human and animal health. Please visit for more information. Forward Looking Statements Except for any historical information, the matters discussed in this press release contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, including with respect to the Company's product candidate's potential to generate revenues and the expected timeframe for results of future studies. Words such as "expects," "anticipates," "intends," "plans," "believes," "seeks," "estimates" and similar expressions or variations of such words are intended to identify forward-looking statements. Although ZIVO believes there is a reasonable basis for each forward-looking statement, we caution you that these statements are based on a combination of facts and factors currently known by us and our expectations of the future, about which we cannot be certain. Our actual future results may be materially different from what we expect due to factors largely outside our control, including risks that our strategic partnerships may not facilitate the commercialization or market acceptance of our products; risks that we will be unable to increase production sufficient to meet demand; risks that our products may not be ready for commercialization in a timely manner or at all; risks that our products will not perform as expected based on results of our preclinical and clinical trials; our ability to raise additional funds; uncertainties inherent in the development process of our products; changes in regulatory requirements or decisions of regulatory authorities; the size and growth potential of the markets for our products; the results of clinical trials; our ability to protect our intellectual property rights; and other risks, uncertainties and assumptions, including those described under the heading 'Risk Factors' in our filings with the Securities and Exchange Commission. These forward–looking statements speak only as of the date of this news release and ZIVO undertakes no obligation to revise or update any forward–looking statements for any reason, even if new information becomes available.

SBI, Land Ports Authority Of India sign MOU to enhance banking services at land ports bordering neighbouring countries
SBI, Land Ports Authority Of India sign MOU to enhance banking services at land ports bordering neighbouring countries

The Print

time29-04-2025

  • Business
  • The Print

SBI, Land Ports Authority Of India sign MOU to enhance banking services at land ports bordering neighbouring countries

This strategic collaboration will strengthen India's border trade ecosystem and provide modern banking solutions to business and individuals at land ports. SBI will partner with LPAI and aspire to improve the trade transactions for Rs 80,000 Crs at present to Rs 2 trillion by 2030. New Delhi [India], April 29 (ANI): The State Bank of India (SBI), the country's largest bank, on Tuesday signed a Memorandum of Understanding (MoU) with Land Ports Authority of India (LPAI) to strengthen banking services infrastructure across 26 land ports bordering our neighbouring countries, a release added. LPAI currently operates 15 land ports across 8 border states adjoining Nepal, Bangladesh, Bhutan, and Myanmar, with 11 more ports sanctioned across states including UP, Bihar, Mizoram, Uttarakhand, and West Bengal. These land ports are handling trade volumes of Rs. 70,952 crores and total passenger movement through these transit points had been 30.46 lakhs as on 23-24 and over a decade there is 15-fold increase in trade and 18-fold increase in passenger movement. Land ports currently handle Rs 71,000 crores in forex trade and nearly 31 Lakhs people cross borders through these land ports annually. In nutshell, these land ports are going to play a very pivotal role in international trade and SBI's presence at these sites will not only contribute towards business growth but also will have a remarkable imprint on the financial landscape of the country while India aspiring for Viksit Bharat by 2047. The said MOU was signed on behalf of SBI by S N Panigrahi, DGM and Shri Vidyadhar Jha, Director (Operations), Land Ports Authority of India. Approx.1900 employees of LPAI under Corporate salary package will be benefited by customised products (offering loans & special financial products), Personal accident insurance, concession in locker rent. Corporate salary package offering of SBI is one of the best in the industry and a better value proposition looking the needs of our customers. SBI will also explore to cater banking needs like forex transactions, LC/BG, Bulk Cargo Insurance, Digital Banking products and array of other banking products in the ports in next six months' time. Being SBI is the lifeline of Indian Economy which offers many cutting-edge digital solutions like YONO 2.0, e-Trade, e-Forex (FTC) worth to mention that Delhi Circle crossed forex turnover of Rs 1 trillion in FY24-25. Apart from LPAI employees, there are employees of Land Border Health Units, which comes under Ministry of Health & Family Welfare, Border Guarding Force (BGF), SSB, BSF, BRO, BOI & Custom & Indirect Taxes Deptt employees. Together, there are more than 5000 employees to whom SBI will serve banking financial services. (ANI) This report is auto-generated from ANI news service. ThePrint holds no responsibility for its content.

SBI ties up with Land Ports Authority for banking services in 26 locations
SBI ties up with Land Ports Authority for banking services in 26 locations

Business Standard

time29-04-2025

  • Business
  • Business Standard

SBI ties up with Land Ports Authority for banking services in 26 locations

State Bank of India (SBI) on Tuesday signed a Memorandum of Understanding (MoU) with Land Ports Authority of India (LPAI) to strengthen banking services infrastructure across 26 land ports bordering neighbouring countries. LPAI currently operates 15 land ports across 8 border states adjoining Nepal, Bangladesh, Bhutan, and Myanmar, with 11 more ports sanctioned across states, including Uttar Pradesh, Bihar, Mizoram, Uttarakhand, and West Bengal. These land ports are handling trade volumes of Rs 70,952 crore, and total passenger movement through these transit points stood at 30.46 lakh as on 2023-24. Over a decade, the ports witnessed a 15-fold rise in trade and an 18-fold increase in passenger movement. Land ports currently handle Rs 71,000 crore in forex trade, and nearly 31 lakh people cross borders through these land ports annually. These land ports are going to play a very pivotal role in international trade, and SBI's presence at these sites will not only contribute towards business growth but also will have a remarkable imprint on the financial landscape of the country, while India aspires for Viksit Bharat by 2047, a joint statement said. As per the MoU, employees of LPAI would get a corporate salary package with host of offers, including personal accident insurance, and concession in locker rent. SBI will also explore catering to banking needs like forex transactions, Bulk Cargo Insurance, digital banking products and an array of other banking products in the ports in the next six months, it said. This strategic collaboration will strengthen India's border trade ecosystem and provide modern banking solutions to businesses and individuals at land ports, it said. SBI will partner with LPAI and aspire to improve the trade transactions for Rs 80,000 crore at present to Rs 2 trillion by 2030. (Only the headline and picture of this report may have been reworked by the Business Standard staff; the rest of the content is auto-generated from a syndicated feed.)

Controls Lifted At Poultry Farm After Virus Eradicated
Controls Lifted At Poultry Farm After Virus Eradicated

Scoop

time28-04-2025

  • Health
  • Scoop

Controls Lifted At Poultry Farm After Virus Eradicated

Press Release – Biosecurity New Zealand While there is still work to be done, the lifting of movement controls is a significant milestone in the response and means that Mainland Poultry can begin the process of returning to business, says Dr van Andel. Movement controls have been lifted from Mainland Poultry's Hillgrove Farm in Otago, after the successful eradication of H7N6 strain of high pathogenic avian influenza (HPAI) says Ministry for Primary Industries chief veterinary officer Dr Mary Van Andel. When HPAI H7N6 was detected in poultry at the property in early December, the Ministry for Primary Industries (MPI) moved swiftly to stamp out the virus. 'While there is still work to be done, the lifting of movement controls is a significant milestone in the response and means that Mainland Poultry can begin the process of returning to business,' says Dr van Andel. 'We're grateful to Mainland Poultry, which did the right thing in notifying us as soon as an exotic disease was suspected and for working with us in partnership to successfully stamp out this disease.' MPI immediately put strict movement controls on the property to prevent goods or anything else that might be carrying the virus leaving the property. Dr van Andel says more than 5,600 tests were carried out on samples from poultry and wild birds, including from 36 flocks across 5 farms linked to Mainland's Hillgrove property. HPAI was not found anywhere other than Hillgrove, giving confidence that the disease had been contained and stamped out. Chickens on the farm were humanely euthanised and disposed of in a secure landfill, along with eggs, litter and manure from the farm. This was followed by an extensive cleaning and disinfection process. 'The processes we have followed – depopulation and disposal, decontamination of the site and extensive surveillance – give us confidence that the virus has been eradicated. MPI staff will continue to support Mainland as the farm is repopulated. 'Good progress is being made to restore trade, with around $300 million of trade in poultry products recovered to date.' MPI has worked with overseas government counterparts and industry partners in New Zealand to meet market requirements and has also proposed alternative assurances to some markets. MPI continues to work towards the reopening of trade for others. Dr van Andel says testing indicates that the infection at Hillgrove is likely to have occurred after free-range laying hens foraging outside were exposed to wild birds with a low pathogenicity (LPAI) virus strain, which then mutated in the hens to become HPAI. 'This is the first time such an event in New Zealand has been documented and our first case of HPAI. We've learned a lot from this response that will help us to prepare for HPAI H5N1 if it spreads here.'

Controls Lifted At Poultry Farm After Virus Eradicated
Controls Lifted At Poultry Farm After Virus Eradicated

Scoop

time28-04-2025

  • Health
  • Scoop

Controls Lifted At Poultry Farm After Virus Eradicated

Movement controls have been lifted from Mainland Poultry's Hillgrove Farm in Otago, after the successful eradication of H7N6 strain of high pathogenic avian influenza (HPAI) says Ministry for Primary Industries chief veterinary officer Dr Mary Van Andel. When HPAI H7N6 was detected in poultry at the property in early December, the Ministry for Primary Industries (MPI) moved swiftly to stamp out the virus. 'While there is still work to be done, the lifting of movement controls is a significant milestone in the response and means that Mainland Poultry can begin the process of returning to business,' says Dr van Andel. 'We're grateful to Mainland Poultry, which did the right thing in notifying us as soon as an exotic disease was suspected and for working with us in partnership to successfully stamp out this disease.' MPI immediately put strict movement controls on the property to prevent goods or anything else that might be carrying the virus leaving the property. Dr van Andel says more than 5,600 tests were carried out on samples from poultry and wild birds, including from 36 flocks across 5 farms linked to Mainland's Hillgrove property. HPAI was not found anywhere other than Hillgrove, giving confidence that the disease had been contained and stamped out. Chickens on the farm were humanely euthanised and disposed of in a secure landfill, along with eggs, litter and manure from the farm. This was followed by an extensive cleaning and disinfection process. 'The processes we have followed – depopulation and disposal, decontamination of the site and extensive surveillance – give us confidence that the virus has been eradicated. MPI staff will continue to support Mainland as the farm is repopulated. 'Good progress is being made to restore trade, with around $300 million of trade in poultry products recovered to date.' MPI has worked with overseas government counterparts and industry partners in New Zealand to meet market requirements and has also proposed alternative assurances to some markets. MPI continues to work towards the reopening of trade for others. Dr van Andel says testing indicates that the infection at Hillgrove is likely to have occurred after free-range laying hens foraging outside were exposed to wild birds with a low pathogenicity (LPAI) virus strain, which then mutated in the hens to become HPAI. 'This is the first time such an event in New Zealand has been documented and our first case of HPAI. We've learned a lot from this response that will help us to prepare for HPAI H5N1 if it spreads here.'

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