Latest news with #MERLIN
Yahoo
22-04-2025
- Science
- Yahoo
Ocergy and Detect Announce Successful Deployment of 3D Radar on Blue Oracle Buoy for Bird Migration Monitoring
AIX-EN-PROVENCE, France, April 22, 2025 /PRNewswire/ -- Ocergy, Inc. and Detect, Inc. are pleased to announce the first phase of their cooperation and the successful offshore deployment of the MERLIN™ Bird and Drone Detection Radar System on Ocergy's BLUE ORACLE Buoy. The radar was installed in early April and will remain operational on the buoy located 30 km east of Port la Nouvelle throughout the bird migration season across the Gulf of Lyon migratory corridor. Early results have been extremely encouraging, demonstrating that the enhanced stability of the OCG-Data™ platform is crucial to the accuracy of bird tracking measurements. The MERLIN radar data acquisition system is functioning flawlessly, with real-time data availability through Ocergy's proprietary SCADA & data management system. "This collaboration represents a significant advancement in offshore bird migration monitoring technology," said Gary Andrews, CEO of DeTect. "The combination of Ocergy's inherently stable OCG-Data offshore buoy with our MERLIN advanced radar technology creates an ideal solution for gathering precise avian data." "This marks the first successful deployment of a bird radar on a low-cost dedicated floater in a far offshore location," said Dominique Roddier, CEO of Ocergy. "This groundbreaking achievement enables us to collect crucial bird migration data in the actual areas used for offshore wind developments." This joint project aims to validate the coupled system, collect critical data on the European bird migration patterns, which will inform environmental impact assessments for offshore developments, and deepen our scientific understanding of avian migratory behaviors. For more information about this collaboration or to request access to the findings, please contact: press@ About Ocergy: At the crossroads between green energy generation and marine environmental restoration, Ocergy develops sustainable offshore solutions that contribute to solving climate change by reducing our carbon footprint while enabling the harvesting of renewable energies and protecting biodiversity. For more information, please visit About DeTect: DeTect, Inc. specializes in applied radar remote sensing technologies and systems for aviation safety, security and surveillance, environmental protection and wind energy, supporting projects worldwide with over 1,200 systems delivered worldwide since 2003. For more information, please visit View original content to download multimedia: SOURCE Ocergy Sign in to access your portfolio
Yahoo
28-03-2025
- Health
- Yahoo
SkylineDx presents landmark findings from the largest prospective multicenter melanoma GEP trial at SSO 2025
Merlin CP-GEP test delivers high clinical utility – Study prospectively confirms precise risk stratification, optimizing SLNB referral recommendations. High clinical impact in subgroups – Merlin Low Risk patients show high negative predictive value (NPV), while Merlin High Risk patients exceed SLNB recommendation thresholds. ROTTERDAM, Netherlands and SAN DIEGO, March 28, 2025 /PRNewswire/ -- SkylineDx, an innovative diagnostics company specializing in the research and development of molecular diagnostics for oncology , inflammatory and infectious diseases, proudly announces Dr. Tina Hieken, a surgical oncologist at Mayo Clinic and one of the principal investigators of the groundbreaking MERLIN_001 study, will present new data at the 2025 Society of Surgical Oncology (SSO) Annual Meeting [1]. Dr. Hieken's presentation, titled Prospective Multicenter Evaluation (MERLIN_001 Trial) of a Clinicopathologic and Gene Expression Profile Test to Predict Sentinel Node Status in T1-T3 cN0 Melanoma, will showcase the final results of this pivotal study, which demonstrates the accuracy of the Merlin CP-GEP test in predicting sentinel lymph node (SLN) metastases in melanoma patients. The MERLIN_001 trial is the largest prospective, blinded study, to evaluate the Merlin CP-GEP test, which is the only commercially avialable GEP test that combines clinical, pathological, and gene expression data into a single algorithm to predict SLN positivity. The study was conducted at 9 renowned US hospitals, which are also top-ranking oncology academic centers. The study's findings validate the test's superior predictive accuracy compared to traditional clinical and pathological factors, which currently guide sentinel lymph node biopsy (SLNB) decisions in melanoma. A total of 1,802 patients were included for whom SLN biopsy material was available. CP-GEP achieved an assay success rate of 97.7%, thus a total of 1,761 patients could be enrolled. The National Comprehensive Cancer Network (NCCN) clinical guidelines recommend SLNB surgery for patients with >10% risk of nodal metastases. This cohort had a 17.6% overall SLNB positivity rate, suggesting effective referral of patients based on current factors. However, 82.4% of patients had a negative sentinel node suggesting no therapeutic benefit from the sentinel node operation. How did Merlin CP-GEP test provide more precise risk stratification, allowing physicians to further optimize SLNB referral decisions and personalize treatment plans? Key findings from the MERLIN_001 study: In this cohort a total of 31 T1a patients with adverse features were referred for SLNB surgery. Merlin identified 80.6% as Low Risk for nodal metastases at a negative predictive value (NPV) of 100%. These patients could consider forgoing SLNB surgery as their risk of nodal metastases is close to 0%. Six patients were identified as Merlin High Risk. Their risk of metastases was with 16.7% well above the >10% guideline threshold, therefore these patients should be referred for surgery. Among the 479 T1b patients, Merlin test identified 67.6% as Low Risk for nodal metastases with a 94.8% NPV. These patients could consider forgoing SLNB surgery as their risk of metastases is close to 5%. Additionally, T1b patients with a Merlin High Risk label had a 16.1% SLNB positivity rate and should be referred for surgery. The study's findings are particularly significant for T2a melanoma patients. This patient subgroup had an SLN positivity rate of 15.5%. Merlin test identified 36.6% as Low Risk at an NPV of 91.9%, reducing their metastatic risk below the 10% threshold for SLNB surgery recommendation. Reclassification of these T2a patients gives them access to more personalized treatment options. The Merlin CP-GEP test also demonstrated exceptional performance in other subgroups, particularly in head and neck melanoma patients. SLNB surgery in this group poses unique challenges due to complex lymphatic drainage and vital anatomical structures. Merlin test identified 43.3% as Low Risk for nodal metastases with an NPV of 95.1%. These patients could consider forgoing SLNB surgery as their risk of metastases is below 5%. "The MERLIN_001 study provides a transformative approach to melanoma risk assessment, ensuring that we can better personalize care for our patients. The test not only refines risk stratification but also addresses critical subgroups, such as head and neck melanoma patients and elderly individuals, who often face complex treatment decisions. By leveraging this groundbreaking tool, we can confidently guide SLNB recommendations and optimizing patient outcomes," said Dr. Tina Hieken. "The MERLIN_001 study results are a breakthrough in melanoma care," said Dharminder Chahal, CEO of SkylineDx. "As the only company to have conducted this large, prospective, blinded trial of the Merlin CP-GEP test in collaboration with esteemed academic institutions in the U.S., we are committed to empowering clinicians with a rigorously validated test backed by high-quality evidence, ensuring patients receive the most informed care possible ." The MERLIN_001 study represents a major milestone in melanoma research, with the potential to enhance clinical decision-making and improve patient outcomes. By offering more accurate risk assessments, the Merlin CP-GEP test empowers healthcare providers to tailor treatment plans to the specific needs of melanoma patients. About the advanced cutaneous melanoma GEP test (Merlin CP-GEP test) CP-GEP is a non-invasive prediction model for cutaneous melanoma patients and is the only commercially available GEP test that combines clinicopathologic (CP) variables with gene expression profiling (GEP) into a single integrated algorithm. This CP-GEP model is also the only GEP test that provides a binary stratification of all patients based on being High or Low Risk for metastasis and thereby assign them to the appropriate surgical action categories as listed in evidence-based cancer treatment, prevention and screening guidelines. The advanced generation CP-GEP model was developed by Mayo Clinic and SkylineDx BV and is the latest commercially launched GEP test, which has been clinically validated in multiple studies on a global basis. More information (including references) may be obtained at and The test has been launched in the United States and Europe as Merlin test. SkylineDx collaborates with diagnostic service providers globally to bring this test to market and increase patient access. About SkylineDx SkylineDx is a biotechnology company focused on research & development of molecular diagnostics in oncology inflammatory, and infectious diseases. SkylineDx uses its expertise to bridge the gap between academically discovered gene expression signatures and commercially available diagnostic products with high clinical utility, assisting healthcare professionals in accurately determining the type or status of disease or predicting a patient's response to treatment. Based on test results, healthcare professionals can tailor the treatment approach to the individual patient. SkylineDx is headquartered in Rotterdam. the Netherlands, complemented by a U.S. base of operations and a CAP/CLIA certified laboratory in San Diego California, USA. To learn more about SkylineDx, please visit Footnotes: 1. T. Hieken et. al. Prospective multicenter evaluation (MERLIN_001 trial, NCT04759781) of a clinicopathologic and gene expression profile test to predict sentinel node status in T1-T3 cN0 melanoma View original content: SOURCE SkylineDx
Yahoo
27-01-2025
- Business
- Yahoo
DeTect to Deliver MERLIN™ True3D™ Bird Detection Radar to Hanseo University's Flight Education Center in South Korea
DeTect's state-of-the-art MERLIN True3D bird radar is the most widely used system for commercial airport and military airfield bird-aircraft strike risk management. PANAMA CITY, Fla., Jan. 27, 2025 /PRNewswire/ -- DeTect, Inc. (DeTect) is shipping a MERLIN True3D Bird Detection Radar (BDR) to Hanseo University's Flight Education Center in South Korea with the system to be installed and operational in mid-February. The system will be used to support flight safety for pilot training and for research, providing real-time bird and drone tracking and strike risk alerting to air traffic controllers and airfield management. DeTect and Hanseo entered into an agreement in June 2024 to deploy the MERLIN system at the training centre airstrip in Taean. "The system will be installed adjacent to the runway and will provide 24-7 real-time information on aircraft, bird and drone activity in support of flight safety" said Gary Andrews DeTect CEO. "The radar detects out to 11 kilometers around the airfield with live displays and risk alerts in the Air Traffic Control tower and other user locations." ABOUT DETECT INC: DeTect is a fully integrated radar company with research, engineering and manufacturing facilities in Florida, Canada and Poland, and offices in North Dakota, California, Hawaii, London, Poland and South Korea. The company's MERLIN BDR is the most proven and widely used system for aircraft-bird strike risk management. Other DeTect products include HARRIER™ Security and Surveillance Radars, the DroneWatcher™ counter-UAS system, MERLIN bird protection systems for wind farms, and the HARRIER Aircraft Detection Lighting System. Since 2003, DeTect has manufactured and delivered over 1100 systems in the US, Canada, the UK, Europe, Africa, and Asia. Reference sites: View original content: SOURCE DeTect, Inc. Sign in to access your portfolio
