Latest news with #MarkCook
Yahoo
19 hours ago
- Health
- Yahoo
Epiminder reports trial outcomes of implantable EEG monitoring device
Epiminder has reported the outcomes from the landmark UMPIRE (sub-scalp monitoring epileptic seizures) trial evaluating Minder, an implantable continuous electroencephalogram (EEG) monitoring system (iCEM). The platform has been validated for its safety and efficacy in capturing high-quality EEG data over extended durations. The trial, which took place across hospitals in Australia, has shown that the Minder system's performance is comparable to the current standard of care scalp-based EEG monitors. Minder has been recognised as a breakthrough device and recently authorised by the US Food and Drug Administration (FDA) through the de novo classification. Key findings from the trial include the safety of the Minder system, without any serious adverse events related to the device or procedure. The EEG signal clarity was found to be on par with the standard 10-20 scalp-based recordings. Clinically relevant outcomes were also observed in 88% of subjects with drug-resistant epilepsy, including those with frequent unreported seizures. Minder's bilateral recording feature demonstrated clinically significant observations that were not detectable with unilateral recordings in 23% of the subjects. Epiminder's chief medical officer and founder Mark Cook said: "The UMPIRE results exceeded our expectations, proving that continuous EEG monitoring over years, not just days, is not only possible but transformative for epilepsy management.' According to the company, this minimally invasive device is tailored for continuous monitoring of the brain's electrographic activity. It enables individuals to be monitored while they engage in their daily activities, providing data for understanding epilepsy and effective treatment alternatives. Implanted under the scalp, the EEG recording and transmitting device is prescribed for use in those aged 18-75 years with drug-resistant epilepsy who cannot use or are not indicated or tolerant of more conservative monitoring tools. It assists physicians in remotely assessing and monitoring patients' conditions, with EEG data available for healthcare providers at various locations from where the data is gathered. "Epiminder reports trial outcomes of implantable EEG monitoring device" was originally created and published by Medical Device Network, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Se produjo un error al recuperar la información Inicia sesión para acceder a tu portafolio Se produjo un error al recuperar la información Se produjo un error al recuperar la información Se produjo un error al recuperar la información Se produjo un error al recuperar la información
Business Wire
2 days ago
- Health
- Business Wire
Epiminder Announces Publication of Landmark Clinical Trial Confirming Safety and Efficacy of the Minder® System
MELBOURNE, Australia & DALLAS--(BUSINESS WIRE)-- Epiminder, a pioneer in implantable continuous EEG monitoring (iCEM™), today announced the publication of results from its landmark UMPIRE (sUb-scalp Monitoring ePileptic seIzuREs) clinical trial in Epilepsia validating the safety and efficacy of its iCEM. The study, conducted across leading Australian hospitals, demonstrated Minder's ability to capture high-quality EEG data for extended periods that are comparable to current standard of care scalp-based EEG monitors. The Minder system is a designated Breakthrough Device and has recently been granted clearance for marketing in the United States by the FDA. A world record five-year continuous EEG recording has recently been reported by Epiminder using the system. 'The UMPIRE results exceeded our expectations, proving that continuous EEG monitoring over years—not just days—is not only possible but transformative for epilepsy management,' said Professor Mark Cook, Epiminder's Founder and Chief Medical Officer. Key Highlights of UMPIRE Clinical Trial: The Minder system was found to be safe, with no device or procedure related Serious Adverse Events EEG signal clarity was comparable to standard of care 10-20 scalp-based recordings Clinically relevant findings were identified in 88% of drug-resistant epilepsy patients, including patients with frequent unreported seizures Minder's unique bilateral recording capability revealed clinically relevant findings not possible with unilateral recordings in 23% of patients Commercial Outlook: Rohan Hoare, Epiminder's CEO, said, 'We are very pleased with the positive impact that Minder can have on the lives of people with epilepsy. Following the FDA authorization in April 2025, Epiminder will initiate a phased U.S. launch in Q3 2025, targeting major epilepsy centers.' Please visit Epilepsia for open access to the UMPIRE publication. Follow Epiminder on LinkedIn and explore for more information. About Minder Minder is a minimally invasive device for continuous monitoring of electrographic activity of the brain, providing epilepsy patients and their doctors with detailed data on brain activity over an extended period. Patients can wear the device as they go about their normal daily activities. Minder's long-term monitoring of patients outside of a controlled clinical environment provides data needed for better understanding and more effective treatment of underlying conditions, including determining the effectiveness of drug therapies and other potential interventions. About Epiminder Founded in 2017 by Professor Mark Cook together with the Bionics Institute, St Vincent's Hospital, the University of Melbourne and Cochlear Limited, Epiminder is a medical device and information solutions company focused on developing diagnostic and treatment tools for epilepsy and other seizure disorders where continuous monitoring is required. Epiminder is headquartered in Melbourne, Australia and has offices in the United States.
Yahoo
25-05-2025
- Business
- Yahoo
CEO & Director of RM Picks Up 200% More Stock
Even if it's not a huge purchase, we think it was good to see that Mark Cook, the CEO & Director of RM plc (LON:RM.) recently shelled out UK£58k to buy stock, at UK£0.99 per share. While that isn't the hugest buy, it actually boosted their shareholding by 200%, which is good to see. This technology could replace computers: discover the 20 stocks are working to make quantum computing a reality. Notably, that recent purchase by Mark Cook is the biggest insider purchase of RM shares that we've seen in the last year. That means that even when the share price was higher than UK£0.94 (the recent price), an insider wanted to purchase shares. While their view may have changed since the purchase was made, this does at least suggest they have had confidence in the company's future. In our view, the price an insider pays for shares is very important. Generally speaking, it catches our eye when insiders have purchased shares at above current prices, as it suggests they believed the shares were worth buying, even at a higher price. RM insiders may have bought shares in the last year, but they didn't sell any. You can see the insider transactions (by companies and individuals) over the last year depicted in the chart below. If you want to know exactly who sold, for how much, and when, simply click on the graph below! Check out our latest analysis for RM There are always plenty of stocks that insiders are buying. If investing in lesser known companies is your style, you could take a look at this free list of companies. (Hint: insiders have been buying them). Looking at the total insider shareholdings in a company can help to inform your view of whether they are well aligned with common shareholders. Usually, the higher the insider ownership, the more likely it is that insiders will be incentivised to build the company for the long term. Our information indicates that RM insiders own about UK£469k worth of shares. But they may have an indirect interest through a corporate structure that we haven't picked up on. We might be missing something but that seems like very low insider ownership. The recent insider purchase is heartening. We also take confidence from the longer term picture of insider transactions. However, we note that the company didn't make a profit over the last twelve months, which makes us cautious. While the overall levels of insider ownership are below what we'd like to see, the history of transactions imply that RM insiders are reasonably well aligned, and optimistic for the future. So while it's helpful to know what insiders are doing in terms of buying or selling, it's also helpful to know the risks that a particular company is facing. While conducting our analysis, we found that RM has 2 warning signs and it would be unwise to ignore them. If you would prefer to check out another company -- one with potentially superior financials -- then do not miss this free list of interesting companies, that have HIGH return on equity and low debt. For the purposes of this article, insiders are those individuals who report their transactions to the relevant regulatory body. We currently account for open market transactions and private dispositions of direct interests only, but not derivative transactions or indirect interests. Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.
Yahoo
25-05-2025
- Business
- Yahoo
CEO & Director of RM Picks Up 200% More Stock
Even if it's not a huge purchase, we think it was good to see that Mark Cook, the CEO & Director of RM plc (LON:RM.) recently shelled out UK£58k to buy stock, at UK£0.99 per share. While that isn't the hugest buy, it actually boosted their shareholding by 200%, which is good to see. This technology could replace computers: discover the 20 stocks are working to make quantum computing a reality. Notably, that recent purchase by Mark Cook is the biggest insider purchase of RM shares that we've seen in the last year. That means that even when the share price was higher than UK£0.94 (the recent price), an insider wanted to purchase shares. While their view may have changed since the purchase was made, this does at least suggest they have had confidence in the company's future. In our view, the price an insider pays for shares is very important. Generally speaking, it catches our eye when insiders have purchased shares at above current prices, as it suggests they believed the shares were worth buying, even at a higher price. RM insiders may have bought shares in the last year, but they didn't sell any. You can see the insider transactions (by companies and individuals) over the last year depicted in the chart below. If you want to know exactly who sold, for how much, and when, simply click on the graph below! Check out our latest analysis for RM There are always plenty of stocks that insiders are buying. If investing in lesser known companies is your style, you could take a look at this free list of companies. (Hint: insiders have been buying them). Looking at the total insider shareholdings in a company can help to inform your view of whether they are well aligned with common shareholders. Usually, the higher the insider ownership, the more likely it is that insiders will be incentivised to build the company for the long term. Our information indicates that RM insiders own about UK£469k worth of shares. But they may have an indirect interest through a corporate structure that we haven't picked up on. We might be missing something but that seems like very low insider ownership. The recent insider purchase is heartening. We also take confidence from the longer term picture of insider transactions. However, we note that the company didn't make a profit over the last twelve months, which makes us cautious. While the overall levels of insider ownership are below what we'd like to see, the history of transactions imply that RM insiders are reasonably well aligned, and optimistic for the future. So while it's helpful to know what insiders are doing in terms of buying or selling, it's also helpful to know the risks that a particular company is facing. While conducting our analysis, we found that RM has 2 warning signs and it would be unwise to ignore them. If you would prefer to check out another company -- one with potentially superior financials -- then do not miss this free list of interesting companies, that have HIGH return on equity and low debt. For the purposes of this article, insiders are those individuals who report their transactions to the relevant regulatory body. We currently account for open market transactions and private dispositions of direct interests only, but not derivative transactions or indirect interests. Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned. Sign in to access your portfolio
Yahoo
25-05-2025
- Business
- Yahoo
Favourable Signals For RM: Numerous Insiders Acquired Stock
Usually, when one insider buys stock, it might not be a monumental event. But when multiple insiders are buying like they did in the case of RM plc (LON:RM.), that sends out a positive message to the company's shareholders. Although we don't think shareholders should simply follow insider transactions, we do think it is perfectly logical to keep tabs on what insiders are doing. Trump has pledged to "unleash" American oil and gas and these 15 US stocks have developments that are poised to benefit. In fact, the recent purchase by Mark Cook was the biggest purchase of RM shares made by an insider individual in the last twelve months, according to our records. So it's clear an insider wanted to buy, even at a higher price than the current share price (being UK£0.94). Their view may have changed since then, but at least it shows they felt optimistic at the time. We always take careful note of the price insiders pay when purchasing shares. Generally speaking, it catches our eye when insiders have purchased shares at above current prices, as it suggests they believed the shares were worth buying, even at a higher price. RM insiders may have bought shares in the last year, but they didn't sell any. The chart below shows insider transactions (by companies and individuals) over the last year. If you want to know exactly who sold, for how much, and when, simply click on the graph below! See our latest analysis for RM There are always plenty of stocks that insiders are buying. If investing in lesser known companies is your style, you could take a look at this free list of companies. (Hint: insiders have been buying them). Over the last quarter, RM insiders have spent a meaningful amount on shares. Specifically, CEO & Director Mark Cook bought UK£58k worth of shares in that time, and we didn't record any sales whatsoever. This could be interpreted as suggesting a positive outlook. Looking at the total insider shareholdings in a company can help to inform your view of whether they are well aligned with common shareholders. A high insider ownership often makes company leadership more mindful of shareholder interests. Our data isn't picking up on much insider ownership at RM, though insiders do hold about UK£469k worth of shares. But they may have an indirect interest through a corporate structure that we haven't picked up on. We might be missing something but that seems like very low insider ownership. The recent insider purchase is heartening. And the longer term insider transactions also give us confidence. But on the other hand, the company made a loss during the last year, which makes us a little cautious. While the overall levels of insider ownership are below what we'd like to see, the history of transactions imply that RM insiders are reasonably well aligned, and optimistic for the future. So these insider transactions can help us build a thesis about the stock, but it's also worthwhile knowing the risks facing this company. In terms of investment risks, we've identified 2 warning signs with RM and understanding them should be part of your investment process. Of course, you might find a fantastic investment by looking elsewhere. So take a peek at this free list of interesting companies. For the purposes of this article, insiders are those individuals who report their transactions to the relevant regulatory body. We currently account for open market transactions and private dispositions of direct interests only, but not derivative transactions or indirect interests. Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
