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A Longevity Expert's Guide to the Best NAD+ Supplements
A Longevity Expert's Guide to the Best NAD+ Supplements

Vogue

time11 hours ago

  • Health
  • Vogue

A Longevity Expert's Guide to the Best NAD+ Supplements

There's no denying, NAD+ (a.k.a. the fountain of youth, bottled) is the hottest wellness trend right now. There are a few different delivery systems—IVs, subcutaneous injections, nasal sprays, and of course, the best NAD+ supplements—to help address everything from loss of muscle mass to brain fog, skin aging, and declining energy stores. Nicotinamide adenine dinucleotide (NAD+) supports virtually every major cellular function, explains board-certified internist and longevity expert Dr. Amanda Kahn. 'It helps your cells generate ATP (energy), protects against oxidative stress, assists in DNA repair, promotes collagen and elastin synthesis for youthful skin, keeps brain and immune cells functioning optimally, and helps maintain microvascular health to ensure proper nutrient delivery throughout tissues' she adds. 'Importantly, NAD+ activates sirtuins, which are proteins that regulate inflammation and repair, both of which are essential for longevity.' Vogue's Favorite NAD+ Supplements: However, NAD+ molecules are too large to penetrate the cell membrane, making its effectiveness a subject of debate. That's where the best NAD+ supplements come in, or rather, the best NAD+ boosters. 'Supplements called NAD+ boosters typically contain NR (nicotinamide riboside), NMN (nicotinamide mononucleotide), or another precursor to NAD+,' says longevity expert, and founder of Timebeam Beauty, Dr. Lamees Hamdan. 'The body uses these precursors to eventually convert to NAD+.' To help boost NAD+ levels and bolster your body's defense against decline, we asked experts to dish on everything from what to look for to the overall benefits to help whittle down our list of the best NAD+ supplements. In This Article: Best Overall NAD+ Supplement: Tru Niagen Age Better NAD+ Tru Niagen Age Better NAD+ Supplement $49 AMAZON Why We Love It: Dr. Kahn recommends Tru Niagen for oral NAD+ supplementation because it is 'well-studied, third-party tested, and trusted for purity.' This supplement contains a patented ingredient called Niagen—which includes nicotinamide riboside (NR), a unique form of vitamin B3 and precursor to NAD+. NR is an efficient way to elevate NAD+ levels because it can penetrate the cell membrane directly. True Niagen's patented ingredient Niagen is also clinically studied for its safety and efficacy in over 35 peer-reviewed published research papers (which it conveniently lists out on its website). It partners with the best-in-class institutions like Mayo Clinic, Harvard, and more, and 90% of its studies are independently researched—meaning they're conducted or funded by a third-party. Dr. Kahn recommends Tru Niagen for oral NAD+ supplementation because it is 'well-studied, third-party tested, and trusted for purity.' This supplement contains a patented ingredient called Niagen—which includes nicotinamide riboside (NR), a unique form of vitamin B3 and precursor to NAD+. NR is an efficient way to elevate NAD+ levels because it can penetrate the cell membrane directly. True Niagen's patented ingredient Niagen is also clinically studied for its safety and efficacy in over 35 peer-reviewed published research papers (which it conveniently lists out on its website). It partners with the best-in-class institutions like Mayo Clinic, Harvard, and more, and 90% of its studies are independently researched—meaning they're conducted or funded by a third-party. Type: NR NR Dose: 2 capsules Best Vegan NAD+ Supplement: Pure Encapsulations NR Longevity Pure Encapsulations NR Longevity Supplement $60 AMAZON Why We Love It: Another favorite of Dr. Kahn, Pure Encapsulations uses the same patented NR complex (Niagen) developed by Tru Niagen. While more research needs to be done, some early trials showed initial evidence that supplementation with NR was safe in humans and could effectively boost NAD levels. It can be a powerful tool to support the health of your cells, heart, muscles, and more. Hypoallergenic, non-GMO, and gluten-free, this vegan capsule also contains broccoli sprout concentrate and trans-resveratrol to supercharge your supplement routine. Another favorite of Dr. Kahn, Pure Encapsulations uses the same patented NR complex (Niagen) developed by Tru Niagen. While more research needs to be done, some early trials showed initial evidence that supplementation with NR was safe in humans and could effectively boost NAD levels. It can be a powerful tool to support the health of your cells, heart, muscles, and more. Hypoallergenic, non-GMO, and gluten-free, this vegan capsule also contains broccoli sprout concentrate and trans-resveratrol to supercharge your supplement routine. Type: Nicotinamide riboside chloride Nicotinamide riboside chloride Dose: 2 capsules Best NAD+ Supplement for Performance: THORNE NiaCel 400 Why We Love It: Thorne is one of the most reputable brands known in the supplement industry. Powered by a unique form of NR that's exclusive to Thorne, it's a great choice for athletes or those looking for more robust NAD+ support, because every batch is NSF Certified for Sport and made without ingredients banned by many major athletic organizations. One dose is only one capsule, so it's also incredibly easy to work into your supplement routine. Thorne is one of the most reputable brands known in the supplement industry. Powered by a unique form of NR that's exclusive to Thorne, it's a great choice for athletes or those looking for more robust NAD+ support, because every batch is NSF Certified for Sport and made without ingredients banned by many major athletic organizations. One dose is only one capsule, so it's also incredibly easy to work into your supplement routine. Type: NR NR Dose: 1 capsule Best NAD+ Supplement With Polyphenols: Elysium Basis NAD Plus Supplement Elysium Basis NAD Plus Supplement $60 AMAZON Why We Love It: With both NAD+ precursor nicotinamide riboside and pterostilbene (PT), a powerful plant polyphenol, this supplement helps boost your cellular energy to protect your cells from the wear and tear we experience from modern life. 'Alcohol, smoking, overeating, stress, environmental toxins are some things that can speed up the decline of NAD+,' says Hamdan. 'There are ways to rebuild those levels both naturally and with a little help.' Polyphenols are also said to help restore NAD+ levels, so we love that this capsule packs a two-for-one punch. The brand also offers a 30-day risk-free trial, so you can try the supplement and if you don't love it, you can get a full refund. With both NAD+ precursor nicotinamide riboside and pterostilbene (PT), a powerful plant polyphenol, this supplement helps boost your cellular energy to protect your cells from the wear and tear we experience from modern life. 'Alcohol, smoking, overeating, stress, environmental toxins are some things that can speed up the decline of NAD+,' says Hamdan. 'There are ways to rebuild those levels both naturally and with a little help.' Polyphenols are also said to help restore NAD+ levels, so we love that this capsule packs a two-for-one punch. The brand also offers a 30-day risk-free trial, so you can try the supplement and if you don't love it, you can get a full refund. Type: NR NR Dose: 2 capsules Best NADH NAD+ Supplement: ProHealth Longevity NADH Pro ProHealth Longevity Longevity NADH Pro Supplement $39 $37 AMAZON Why We Love It: For mood, memory, energy, and focus support, these lozenges taste like lemon and easily dissolve under your tongue. It uses NADH—NAD+ is an oxidized form of nicotinamide adenine whereas NADH is a reduced form of nicotinamide adenine, meaning it gains the electron lost by NAD+— which is able to enter the cell via the membrane. Early research found that there is promise with oral NADH for treating chronic fatigue syndrome, with more clinical trials underway. For mood, memory, energy, and focus support, these lozenges taste like lemon and easily dissolve under your tongue. It uses NADH—NAD+ is an oxidized form of nicotinamide adenine whereas NADH is a reduced form of nicotinamide adenine, meaning it gains the electron lost by NAD+— which is able to enter the cell via the membrane. Early research found that there is promise with oral NADH for treating chronic fatigue syndrome, with more clinical trials underway. Type: NADH NADH Dose: 1 lozenge Best NAD+ Supplement With Resveratrol: Omre Nicotinamide Riboside + Resveratrol NAD Supplement Omre Nicotinamide Riboside + Resveratrol NAD Supplement $60 AMAZON Why We Love It: Not only does this capsule help boost NAD+ production in cells, the secret molecule to your best skin ever, by using precursor NR, it adds even more benefits with resveratrol. Resveratrol is a powerful antioxidant—found in grapes—best known for its research-backed health benefits (and the root of what we know as the 'French paradox.') 'I like NAD+ boosters stacked with other ingredients as I find that gives you the best results,' says Hamdan. The brilliance of the formula is not just what it's made with, but what it's made without—there are no fillers, artificial additives, or preservatives. Not only does this capsule help boost NAD+ production in cells, the secret molecule to your best skin ever, by using precursor NR, it adds even more benefits with resveratrol. Resveratrol is a powerful antioxidant—found in grapes—best known for its research-backed health benefits (and the root of what we know as the 'French paradox.') 'I like NAD+ boosters stacked with other ingredients as I find that gives you the best results,' says Hamdan. The brilliance of the formula is not just what it's made with, but what it's made without—there are no fillers, artificial additives, or preservatives. Type: NR NR Dose: 2 capsules Best Sublingual NAD+ Supplement: Renue by Science Nicotinamide Riboside Powder Renue by Science Nicotinamide Riboside Powder $109 $79 AMAZON Why We Love It: Not only is this powder manufactured in a GMP-compliant facility, the brand also puts every supplement through stringent third-party testing for quality assurance. It's great for those who are wary of taking pills and prefer to customize their supplement routine. It comes in a powder format, so you can put the zesty, citrus-flavored dust directly under your tongue, mix it in water, or blend it with your favorite beverage. The brand also prominently lists their certificate of analysis on their website, a major bonus for users who appreciate transparency. Not only is this powder manufactured in a GMP-compliant facility, the brand also puts every supplement through stringent third-party testing for quality assurance. It's great for those who are wary of taking pills and prefer to customize their supplement routine. It comes in a powder format, so you can put the zesty, citrus-flavored dust directly under your tongue, mix it in water, or blend it with your favorite beverage. The brand also prominently lists their certificate of analysis on their website, a major bonus for users who appreciate transparency. Type: NRC NRC Dose: 2 scoops Best Liposomal NAD+ Supplement: Rho Nutrition Liposomal NAD+ Rho Nutrition Liposomal NAD+ Supplement $56 AMAZON Why We Love It: Rho's liquid NAD+ is the ingestible answer to those who want a vitamin B3 boost without getting an expensive IV drip. With a tangy lemon flavor and a vegan, sugar-free, keto-friendly, non-GMO, gluten, dairy-free, and soy-free formulation, customers reported loving the ability to customize their daily dosage and beat the afternoon slump. Rho's liquid NAD+ is the ingestible answer to those who want a vitamin B3 boost without getting an expensive IV drip. With a tangy lemon flavor and a vegan, sugar-free, keto-friendly, non-GMO, gluten, dairy-free, and soy-free formulation, customers reported loving the ability to customize their daily dosage and beat the afternoon slump. Type: NAD NAD Dose: 4 milliliters Best Powder NAD+ Supplement: Timebeam Beauty Bounce Mode Healthy Pixie Timebeam Beauty Bounce Mode Healthy Pixie Supplement $49 TIMEBEAM BEAUTY Why We Love It: While NAD+ is the ingredient everyone is obsessing over, the truth is that NAD+ does not work by itself. Hamdan formulated this powder with NAD+ 'friends' like vitamin C, ribose, and rhodiola. 'This helps increase the efficacy and bioavailability of the NAD+,' says Hamdan. Hamdan also sought out an incredibly powerful and innovative NAD+ booster for this formula (we found it's a trademarked complex called RiaGev-WS), which she says is superior to NMN and NR. 'It's a direct source of NAD+, meaning it boosts not only NAD+ but two other longevity molecules in the cells called ATP and glutathione, while also decreasing cortisol levels,' says Hamdan. 'It's also easily absorbed by your body—remember if you don't absorb it, you can't use it.' The sprinkle-able, fast-melting powder melts right onto your tongue or can be mixed into hot or cold drinks which makes it one of the easiest ways to get your daily boost of NAD+. While NAD+ is the ingredient everyone is obsessing over, the truth is that NAD+ does not work by itself. Hamdan formulated this powder with NAD+ 'friends' like vitamin C, ribose, and rhodiola. 'This helps increase the efficacy and bioavailability of the NAD+,' says Hamdan. Hamdan also sought out an incredibly powerful and innovative NAD+ booster for this formula (we found it's a trademarked complex called RiaGev-WS), which she says is superior to NMN and NR. 'It's a direct source of NAD+, meaning it boosts not only NAD+ but two other longevity molecules in the cells called ATP and glutathione, while also decreasing cortisol levels,' says Hamdan. 'It's also easily absorbed by your body—remember if you don't absorb it, you can't use it.' The sprinkle-able, fast-melting powder melts right onto your tongue or can be mixed into hot or cold drinks which makes it one of the easiest ways to get your daily boost of NAD+. Type: RiaGev-WS RiaGev-WS Dose: 1 packet Best NMN NAD+ Supplement: Wonderfeel Youngr NMN Wonderfeel Youngr NMN Supplement $88 WONDERFEEL Why We Love It: With a patented blend of NMN, vitamin D, resveratrol, and olive antioxidant super ingredient hydroxytyrosol, this NAD+ supplement is ranked among the best of the best according to longevity experts. 'Oral precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), are more easily absorbed and efficiently converted to NAD+ within cells,' says Kahn. There's also promising pre-clinical research that NMN has beneficial effects on cognitive function. The brand has an impressive list of medical advisors and scientific experts on board, including Harvard-, Yale-, and Columbia-trained Dr. Andrew Salzman, MD, who helped develop the formula. With a patented blend of NMN, vitamin D, resveratrol, and olive antioxidant super ingredient hydroxytyrosol, this NAD+ supplement is ranked among the best of the best according to longevity experts. 'Oral precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), are more easily absorbed and efficiently converted to NAD+ within cells,' says Kahn. There's also promising pre-clinical research that NMN has beneficial effects on cognitive function. The brand has an impressive list of medical advisors and scientific experts on board, including Harvard-, Yale-, and Columbia-trained Dr. Andrew Salzman, MD, who helped develop the formula. Type: NMN NMN Dose: 2 capsules Everything You Need to Know

Eden Expands Metabolic Health Access Services with NAD⁺ via Injections, Patch, and Nasal-Spray Formats
Eden Expands Metabolic Health Access Services with NAD⁺ via Injections, Patch, and Nasal-Spray Formats

Yahoo

time29-05-2025

  • Business
  • Yahoo

Eden Expands Metabolic Health Access Services with NAD⁺ via Injections, Patch, and Nasal-Spray Formats

Three clinician-guided options offer flexible, non-oral delivery paths for adults exploring NAD⁺ as part of their wellness routines. DENVER, May 29, 2025 /PRNewswire/ -- Eden, the leading health platform connecting individuals with independent licensed providers and pharmacies focused on metabolic health, today announced the nationwide availability of its NAD⁺ access program. The program includes subcutaneous injections, a once-weekly transdermal patch (Ionto STAT™), and a rapid-absorbing nasal spray. These options give adults new ways to consult with clinicians about whether NAD⁺ may complement their health and wellness goals. Nicotinamide adenine dinucleotide (NAD⁺) is a coenzyme found in all living cells that plays a role in cellular metabolism. Scientific literature suggests that NAD⁺ contributes to essential biological functions, including mitochondrial energy production, DNA repair, and cellular stress responses. NAD⁺ levels are known to decline with age, sparking growing interest in its potential role in aging-related cellular processes. Through Eden's platform, adults in all 50 states can access clinician consultations to determine if NAD⁺ is appropriate for their individual needs. Provider-guided protocols may include non-oral formats that are intended to support general wellness, particularly cellular functions related to metabolism and healthy aging. These offerings are available through licensed providers and compounding pharmacies, and are not approved by the FDA for any disease-specific use. "Many people are exploring NAD⁺ as a supplement to support cellular processes associated with energy metabolism and aging," said Adam McBride, CEO and co-founder of Eden. "Our platform ensures this exploration happens under clinician supervision, with flexibility and accountability." "We believe access and accountability go hand in hand," said Josh Khan, president and co-founder of Eden. "Our network partner providers set realistic expectations. While some individuals may report subjective improvements over time, outcomes vary widely and depend on many personal and clinical factors. Providers monitor patient response and adjust protocols based on evolving research and patient goals." Monthly plans begin at $119, terms apply. Existing Eden members can discuss NAD⁺ options during routine check-ins. Learn more at About Eden Eden is a health company that connects individuals with licensed doctors, compounding pharmacies, and nutrition solutions designed to support metabolic health. Through a seamless online experience, Eden helps patients explore personalized treatment options, offering a convenient approach to overall wellness support. Disclaimer: NAD⁺ formulations accessed through Eden's network are available via licensed healthcare providers and compounding pharmacies. These compounds are not approved by the Food and Drug Administration (FDA) to diagnose, treat, cure, or prevent any disease. Individual results may vary. These statements have not been evaluated by the FDA. View original content to download multimedia: SOURCE Eden Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Hydration Room Launches Industry-First NAD+ IV Membership with Tiered Dosing to Support Brain Health, Energy, and Longevity
Hydration Room Launches Industry-First NAD+ IV Membership with Tiered Dosing to Support Brain Health, Energy, and Longevity

Yahoo

time20-05-2025

  • Health
  • Yahoo

Hydration Room Launches Industry-First NAD+ IV Membership with Tiered Dosing to Support Brain Health, Energy, and Longevity

IRVINE, Calif., May 20, 2025 /PRNewswire/ -- Hydration Room, a leading provider of doctor-founded IV therapy and wellness treatments, proudly announces the launch of its groundbreaking NAD+ IV Membership, the first of its kind in the industry. This new offering provides monthly access to NAD+ therapy through three flexible dosing tiers, designed to promote consistency, personalized care, and optimal outcomes for mental clarity, energy, and long-term vitality. Built for Brain Health, Energy, and Longevity NAD+ is a vital coenzyme shown to support cognitive function, improve focus, sleep, and clarity, enhance energy, and promote cellular repair, all of which are crucial for aging well and living fully. Hydration Room has administered over 11,000 NAD+ treatments, making it one of the most experienced providers of NAD+ therapy in California. To support brain health comprehensively, Hydration Room offers NAD+ IVs, injections, and nasal sprays, giving patients flexible options to maintain their wellness routine. Introducing NAD+ Memberships: Consistency That Changes Everything. Available in 500mg, 750mg and 100mg tiers, the NAD+ Membership allows patients to choose a plan that aligns with their goals, lifestyle, and individual tolerance. This model gives patients structured access to a treatment that is often underutilized due to cost or confusion around dosing. By pairing expert guidance with routine care, Hydration Room is making NAD+ more accessible, and more effective, than ever before. "We created this membership to help more people unlock the benefits of NAD+ through access and consistency," said Michelle Mendoza, CEO of Hydration Room. "Our goal is to remove the guesswork and offer an easy, expert-guided path to feeling better, sharper, and more energized—every month." The NAD+ Membership is grounded in clinical insight and personalized protocols. Most patients begin with a series of loading doses, then transition to a monthly cadence, with dosing options starting at 500mg and progressing up to 1000mg, based on individual needs and tolerance. All dosing is supervised by Hydration Room's medical team. "As both a physician and a patient, I personally receive monthly NAD+ therapy because its benefits for cellular health, cognitive function, and energy are that impactful," said Dr. Brett Florie, Founder and Chief Medical Officer of Hydration Room. "Consistency is key. We've seen that ongoing NAD+ support can play a powerful role in long-term vitality, resilience, and overall wellness. Our goal is to make that level of care accessible to every patient committed to their health." Membership Includes Premium Perks In addition to monthly NAD+ therapy, members enjoy exclusive benefits, including shareable credits, discounts on other services, and ongoing provider support making it easy to stay on track and see results. Get Started with a Special Offer For a limited time, new members can receive 50% off their first month, making it easy and low-risk to begin their NAD+ journey. With more than 30 clinic locations across Los Angeles, Orange County, and San Diego, Hydration Room makes proactive, physician-driven wellness both convenient and accessible. Many locations feature private treatment rooms designed to support comfort and discretion. Every patient begins their journey with a complimentary consultation led by a certified Nurse Practitioner, ensuring each NAD+ protocol and IV treatment plan is thoughtfully tailored to individual health goals and lifestyle needs. For more information or to join the NAD+ Membership, visit [ or contact your nearest Hydration Room location. About Hydration RoomFounded in 2014 by board-certified anesthesiologist Dr. Brett Florie, Hydration Room is redefining modern wellness with personalized, physician-designed IV and injection therapy. With over 30 clinics across Southern California, Hydration Room blends medical expertise with a high-touch patient experience to deliver fast, effective treatments that support energy, immunity, recovery, longevity, and overall wellness. From NAD+ therapy to custom treatment plans guided by licensed medical professionals, Hydration Room empowers patients to take control of their health—starting at the cellular level. Hydration Room Tina McClellandVP View original content to download multimedia: SOURCE Hydration Room Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Elite Mobile IV Redefines Wellness in Nashville and Raleigh, Delivering Hospital-Grade IV Therapy in Under an Hour
Elite Mobile IV Redefines Wellness in Nashville and Raleigh, Delivering Hospital-Grade IV Therapy in Under an Hour

Business Insider

time27-04-2025

  • Health
  • Business Insider

Elite Mobile IV Redefines Wellness in Nashville and Raleigh, Delivering Hospital-Grade IV Therapy in Under an Hour

United States, April 27, 2025 -- Elite Mobile IV, a leading provider of mobile intravenous therapy, is transforming the wellness scene in the South by delivering fast, hospital-grade hydration and nutrient treatments straight to homes, hotels, and offices—often in under an hour. With a stronghold in Nashville and Raleigh, the company sets the standard for at-home care with emergency-trained nurses, personalized drips, and unmatched convenience. Elite Mobile IV was founded on one bold belief: feeling better shouldn't mean waiting. Whether one is battling dehydration, flu symptoms, jet lag, a hangover, or chronic fatigue, help arrives quickly—with ER-level care delivered wherever one is. Clients can choose from a wide range of customized IV drips, including: - $349 Hydration Bag: Packed with electrolytes to rehydrate fast. - Super Immunity Drip: Boosts immune response—popular during flu season in Raleigh. - Hangover Relief IV: Targets headaches, nausea, and fatigue—especially loved by weekend warriors in Nashville. - NAD+ and Myers' Cocktail: Designed for anti-aging, mental clarity, and long-term health. Every treatment is sourced from FDA-approved compounding pharmacies and administered by licensed nurses with emergency or critical care experience. Before treatment, clients complete a simple intake form and receive a tailored wellness consult to ensure the right drip for their needs. 'Our clients don't just want convenience—they want peace of mind,' said a company representative. 'We bring both.' Elite Mobile IV isn't just a one-time fix. Starting at $299/month, their membership program offers up to 35% off drips, priority booking, and access to advanced offerings like genetic testing and nutritional counseling. It's ideal for clients seeking regular support for chronic conditions, performance recovery, or proactive health. With 90% of clients reporting immediate symptom relief, Elite Mobile IV has built a loyal following across Nashville and Raleigh. 'Elite Mobile IV is now my first recommendation for patients needing same-day rehydration,' said John Picoulas, a South Carolina pharmacist. 'They were professional and knowledgeable. I was battling a GI bug, which helped a ton—without the hassle of going to a clinic,' added client John Lawrence Holliday. Available every day from 9 AM to 9 PM—including holidays—Elite Mobile IV serves seven Southern cities, with Nashville and Raleigh as flagship markets. As the company continues expanding, its mission remains clear: to make cutting-edge wellness fast, safe, and accessible for all. Book now at or call/text to schedule a personalized IV drip. Relief is just a few clicks away. About Elite Mobile IV: Elite Mobile IV is a licensed mobile IV therapy provider specializing in fast, professional-grade hydration, vitamin infusions, and recovery solutions. Staffed by emergency-trained nurses, the company serves Nashville, Raleigh, and five other Southern cities. Treatments are sourced from FDA-approved pharmacies and delivered with unmatched care and convenience. Release ID: 89158497 In the event of detecting errors, concerns, or irregularities in the content shared in this press release that require attention or if there is a need for a press release takedown, we kindly request that you inform us promptly by contacting error@ (it is important to note that this email is the authorized channel for such matters, sending multiple emails to multiple addresses does not necessarily help expedite your request). Our dedicated team will promptly address your feedback within 8 hours and take necessary actions to resolve any identified issues diligently or guide you through the removal process. Providing accurate and dependable information is our utmost priority.

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