04-05-2025
Common Household Spice Could Mess With Your Medications
Based on facts, either observed and verified firsthand by the reporter, or reported and verified from knowledgeable sources.
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A new study suggested that certain types of cinnamon products could interfere with some medications due to their metabolic impacts.
Researchers from the National Center for Natural Products Research (NCNPR) at the University of Mississippi illustrated this by testing the absorption of medications following cinnamon intake in a material simulating fasting gastric fluid.
"People who suffer from chronic diseases – like hypertension, diabetes, cancer, arthritis, asthma, obesity, HIV, AIDS or depression – should be cautious when using cinnamon or any other supplements," Shabana Khan, a principal scientist in the natural products center, said in the press release, adding "By definition, supplements are not meant to treat, cure or mitigate any disease."
Why It Matters
The common spice is found in many homes, restaurants, and coffee houses and while researchers say having a little of it is harmless, larger quantities could cause potential medication efficacy issues.
It has long been known to have good metabolic and anti-inflammatory properties and thus has been marketed as supplements in different forms, including oils, powder and capsules.
What To Know
The study from the NCNPR says not knowing the source and quantity of cinnamaldehyde in the cinnamon can create dangerous situations, especially for those with chronic conditions like diabetes, heart disease, cancer and depression.
When taken in large doses, like those which can be found in some supplements, it can lead to a change in how quickly the large intestine can absorb the medicine, and thus, how effective the treatment will be on an individual.
Researchers tested using cinnamaldehyde, the active component that gives the spice its scent and flavor.
They found that the absorption of medications into the simulated gastric fluid was slowed after adding cinnamaldehyde in comparison to the fluid that did not have it added.
While the results aren't definitive, they do point in a direction of danger, leading researchers to caution medication takers and seek further research.
NCNPR Associate Director Amar Chittiboyina said the issues don't extend to all cinnamon products.
He said cinnamon oil doesn't have the same risk of drug interactions as cinnamon bark, which can have a large amount of coumarin, a blood thinner. This is mostly found in Cassia cinnamon from southern China, according to Chittiboyina.
"In contrast, true cinnamon from Sri Lanka carries a lower risk due to its reduced coumarin content," he explained in the press release. "Coumarin's anticoagulant properties can be hazardous for individuals on blood thinners."
In this stock image, cinnamon is seen in Berlin on January 20.
In this stock image, cinnamon is seen in Berlin on January People Are Saying
Bill Gurley, a principal scientist in the Ole Miss center and co-author of the study, said: "We know there's a potential for cinnamaldehyde to activate these receptors that can pose a risk for drug interactions. That's what could happen, but we won't know exactly what will happen until we do a clinical study."
Shabana Khan, a principal scientist in the natural products center, said in the press release: "Health concerns could arise if excessive amounts of supplements are consumed without the knowledge of health care provider or prescriber of the medications. Overconsumption of supplements could lead to a rapid clearance of the prescription medicine from the body, and that could result in making the medicine less effective."
What Happens Next?
Gurley said a clinical study is needed to further study the effects of cinnamaldehyde on patients' medication consumption and efficacy of those medications.
While those studies are not yet completed, researchers say people should talk to their doctor before adding any cinnamon supplements to their diet in addition to medications.
