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Weill Cornell and NYGC study reveals new method for cancer detection
Weill Cornell and NYGC study reveals new method for cancer detection

Yahoo

time14-04-2025

  • Health
  • Yahoo

Weill Cornell and NYGC study reveals new method for cancer detection

Researchers from Weill Cornell Medicine (WCM) and New York Genome Center (NYGC), US, have identified an 'accurate' and 'sensitive' method for identifying cancer through blood tests, leveraging whole-genome sequencing and an error-correcting technique. Through a study, the researchers assessed the performance of a new sequencing platform from Ultima Genomics, demonstrating that the platform's affordability does not compromise the depth of coverage. This enables the detection of minute concentrations of circulating tumour DNA. The researchers further enhanced the method's precision by incorporating an error correction mechanism. According to Weill Cornell, liquid biopsy technology, which is based on blood tests for early cancer detection, has faced significant hurdles due to the challenges of identifying cancer's mutational signatures from low concentrations of tumour DNA. The Landau laboratory, situated at the Meyer Cancer Center of WCM and NYGC, claims to have dedicated nearly a decade to refining whole-genome sequencing methods to address these challenges, moving beyond targeted sequencing of expected mutation sites. A 2024 study demonstrated the capability to identify advanced stages of melanoma and lung cancer through blood samples from patients, eliminating the need for sequencing data from tumour specimens. The latest study leverages the cost-effectiveness of the new sequencing platform, and the researchers demonstrated the platform's capability to identify tumour DNA at parts-per-million concentration levels, using known mutational patterns in patient tumours as a reference. All samples were collected with informed consent from the subjects involved. Researchers then improved the approach's 'accuracy' by including the error-correction method, which leverages redundant data in natural two-stranded DNA. This combo method yielded extremely low error rates, suggesting the possibility of using the technique on blood samples without the requirement for tumour accessibility. Partnerships with other research teams have shown the method's potential in detecting and evaluating minimal cancer levels in individuals with bladder cancer and melanoma using only blood samples. This research received support from the National Cancer Institute of the National Institutes of Health. Further backing came from the Melanoma Research Alliance Established Investigator Award, the Mark Foundation Aspire Award, and the Burroughs Wellcome Fund Career Award for Medical Scientists. NewYork-Presbyterian/Weill Cornell Medical Center urologic oncologist and Englander Institute for Precision Medicine chief research officer Dr Bishoy Faltas said: 'This collaboration allowed us to analyse circulating tumour DNA from patients with bladder cancer and identify the distinct mutational signatures that my lab has extensively studied.' "Weill Cornell and NYGC study reveals new method for cancer detection" was originally created and published by Medical Device Network, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site.

What channel is TGL finals on tonight? Time, TV schedule for TGL championship matches
What channel is TGL finals on tonight? Time, TV schedule for TGL championship matches

USA Today

time25-03-2025

  • Sport
  • USA Today

What channel is TGL finals on tonight? Time, TV schedule for TGL championship matches

What channel is TGL finals on tonight? Time, TV schedule for TGL championship matches Show Caption Hide Caption What it's like to experience a TGL golf match firsthand Join Averee Dovsek behind the scenes of a TGL golf match for an exclusive look at the excitement and unforgettable experience! The inaugural champion of the TGL golf league will be crowned tonight. Will it be New York Golf Club or Atlanta Drive GC? The TGL finals got started Monday night. If we see a sweep with tonight's first match, that'll be it and the grand prize will be won. If there's a split, we go on to a decisive Match 3 right afterward. Tiger Woods and Rory McIlroy won't be playing tonight (their teams missed the playoffs), but there are plenty of PGA Tour stars vying for the indoor golf league's first championship. Justin Thomas, Billy Horschel, Patrick Cantlay and Lucas Glover represent Atlanta, while NYGC fields Xander Schauffele, Rickie Fowler, Matt Fitzpatrick and Cameron Young. Watch TGL playoffs live on Fubo (free trial) Here's everything you need to know about the match, including time, TV schedule and streaming information: What time is TGL finals on today? Who: Atlanta Drive GC vs. New York Golf Club Atlanta Drive GC vs. New York Golf Club When: 7 p.m. ET Tuesday, March 25 Match 2 of the TGL finals is set to begin at 7 p.m. If the series is split, the deciding Match 3 will begin immediately afterward. What channel is TGL golf on today? TV channel: ESPN ESPN Live streaming: ESPN+ | Fubo (free trial) Ticket prices for tonight's TGL match were available for $158 (before fees) on StubHub as of Friday. Shop for TGL tickets on StubHub TGL schedule The TGL season concludes with the championship round March 24-25. Here's a look at the TGL schedule for the playoffs: March 17: Semifinals, NYGC 6, LAGC 4 Semifinals, NYGC 6, LAGC 4 March 18: Semifinals, Atlanta 9, The Bay 3 Semifinals, Atlanta 9, The Bay 3 Monday: Finals, Match 1 | Atlanta vs. NYGC Finals, Match 1 | Atlanta vs. NYGC Tonight: Finals, Atlanta vs. NYGC | Match 2 and 3*, 7 p.m. and 9 p.m.*, ESPN *- if necessary We occasionally recommend interesting products and services. If you make a purchase by clicking one of the links, we may earn an affiliate fee. USA TODAY Network newsrooms operate independently, and this doesn't influence our coverage.

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