Latest news with #PanGIA®
Business Wire
4 days ago
- Business
- Business Wire
PanGIA Biotech Unveils AI-Driven Urine Test Data for Early Prostate Cancer Detection at ASCO 2025
CHICAGO--(BUSINESS WIRE)--PanGIA Biotech, a leader in non-invasive cancer diagnostics, presented findings at the 2025 Annual Meeting of the American Society of Clinical Oncology (ASCO) from a prospective, multi-center validation study evaluating its AI-powered, urine-based platform for early-stage prostate cancer detection. The study, Development and validation of an AI-enabled prediction of prostate cancer (PCa) using urine-based liquid biopsy (Abstract #3080) is the first to clinically validate PanGIA®'s novel approach pairing proprietary chemistry with machine learning. Share The study, Development and validation of an AI-enabled prediction of prostate cancer (PCa) using urine-based liquid biopsy (Abstract #3080), is the first to clinically validate PanGIA®'s novel approach—pairing proprietary chemistry with machine learning to detect cancer-specific biosignatures from a single, non-invasive urine sample. 'This study confirms what we've believed from the start: there's power in non-invasive, data-driven diagnostics,' said Holly Magliochetti, CEO of PanGIA Biotech. 'Our platform helps clinicians detect prostate cancer when intervention is most effective—without costly or invasive procedures.' Key findings presented included: Study Cohort: 197 biopsy-confirmed prostate cancer patients and 84 healthy controls. Classifier Performance: Achieved an F1 score of 0.843 with a recall of 0.967 in distinguishing cancer from non-cancer subjects. Gleason Score Cohorts: Maintained high recall (>0.89) across Gleason scores 6 through 10, with F1 scores ranging from 0.799 to 0.838. Non-Invasive Advantage: Demonstrated strong performance in detecting intermediate- and low-grade cancers, offering a less invasive alternative to traditional diagnostics. Unlike invasive biopsies or blood-based tests that often miss early-stage cases, PanGIA's approach analyzes urinary biosignatures using proprietary AI models—eliminating the need for sequencing and enabling cost-effective, globally scalable testing. Previously published in The Analyst, a journal of the Royal Society of Chemistry¹, the PanGIA platform is designed for diverse healthcare environments and holds promise for broad global adoption. About PanGIA Biotech PanGIA Biotech develops AI-integrated, urine-based liquid biopsy solutions designed for global scalability. The PanGIA® platform supports early detection, monitoring, and disease management—including cancer as early as Stage 1. With machine learning at its core, the platform deciphers biomolecular patterns to deliver accurate diagnostic insights. Backed by patents and peer-reviewed research, PanGIA is committed to reshaping healthcare through innovation. Learn more at ¹ Lim FB, et al. 'A Colorimetric Chemical Tongue Detects And Distinguishes Between Multiple Analytes.' The Analyst. 2022;147(23):5283–5292. doi:10.1039/D2AN01615J
Business Wire
30-04-2025
- Business
- Business Wire
PanGIA Biotech Announces Upcoming ASCO 2025 Poster Presentation of Collaborative Research
DELRAY BEACH, Fla.--(BUSINESS WIRE)--PanGIA Biotech, a company advancing urine-based, AI-driven diagnostics for early cancer detection, today announced that an abstract co-authored by researchers from PanGIA Biotech, Entopsis Inc., and Genetics Institute of America has been accepted for presentation at the 2025 Annual Meeting of the American Society of Clinical Oncology (ASCO), taking place May 30–June 3, 2025, in Chicago, Illinois. Development and validation of an AI-enabled prediction of prostate cancer (PCa) using urine-based liquid biopsy (Abstract #3080) has been accepted for presentation in the poster session titled Developmental Therapeutics—Molecularly Targeted Agents and Share The abstract, titled Development and validation of an AI-enabled prediction of prostate cancer (PCa) using urine-based liquid biopsy (Abstract #3080), has been accepted for presentation in the poster session titled Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology. The presentation highlights collaborative research contributing to PanGIA's AI-driven, urine-based diagnostic platform. The work integrates biomolecular pattern analysis and machine learning to support the development of scalable, non-invasive solutions in cancer care. ASCO 2025 Presentation Details Date: June 2, 2025 Time: 1:30 – 4:30 p.m. CDT Location: McCormick Place, Chicago, IL 'This presentation reflects our focus on developing non-invasive, scalable diagnostics rooted in the promise of liquid biopsy innovation,' said Holly Magliochetti, CEO of PanGIA Biotech. 'We remain committed to advancing technologies that may support earlier cancer detection and improve access to care globally.' Co-authors on the abstract include researchers from PanGIA Biotech, Entopsis Inc., and the Genetics Institute of America. About PanGIA Biotech PanGIA Biotech develops AI-integrated liquid biopsy technology designed for global scalability. The PanGIA® platform is a transformative solution for detecting, monitoring, and managing diseases, including cancers as early as Stage 1. Powered by machine learning, this urine-based platform profiles biomolecular patterns to deliver accurate diagnostic insights. PanGIA's technology is grounded in peer-reviewed research and R&D success, supported by patents to the company for global diagnostic development. With a steadfast commitment to research and innovation, PanGIA's vision is to revolutionize disease detection and improve healthcare worldwide. For more information, visit
