Latest news with #Pearsanta
Yahoo
25-03-2025
- Business
- Yahoo
Pearsanta acquires patents for adductomics-based DNA damage detection
Aditxt subsidiary Pearsanta has acquired patents associated with adductomics-based DNA damage detection, to make significant advancements in cancer diagnostics. Valued at nearly $1m, the acquisition involved the issuance of Pearsanta's convertible preferred stock. This move aligns with the company's mission to progress accessible early cancer identification and prevention worldwide. The patents cover proprietary progressions in DNA adduct detection and analysis, which can evaluate genomic instability that occurred due to environmental toxins and metabolic byproducts. DNA adducts are chemical modifications to DNA nucleotides that occur due to carcinogens and are among the earliest indicators of cancer risk. Pearsanta's Mitomic Technology platform leverages biomarkers of mitochondrial DNA for 'non-invasive' detection of cancer. The company's acquisition enables it to expand its capabilities in assessing carcinogen exposure and genomic instability before the occurrence of permanent mutations. Over the next two to three years, Pearsanta will focus on clinical validation, regulatory submissions along with commercialisation activities for integrating the technology into its diagnostic portfolio. By using urine, blood, or solid tissue samples, the company plans to 'develop' its platform as a comprehensive assessment tool for DNA adducts, offering actionable insights into the damage of DNA. The company is progressing with a strategic development plan to introduce adductomics-based diagnostics to the market. This includes the focus on clinical validation for confirming the 'effectiveness' of the technology, regulatory submissions for supporting integration into laboratory-developed tests (LDTs), and scalability within labs certified by Clinical Laboratory Improvement Amendments (CLIA) or College of American Pathologists (CAP). By identifying DNA damage prior to disease progression, the adductomics technology claims to 'reduce" the overall economic load of cancer. Pearsanta president Chris Mitton said: 'We believe that Pearsanta is uniquely positioned to shift cancer care from reactive treatment to proactive prevention. 'In underserved regions, where access to oncology treatments remains limited, we believe that adductomics-based screening could provide a cost-effective tool for early cancer risk assessment, empowering preventive measures when they are most effective.' "Pearsanta acquires patents for adductomics-based DNA damage detection" was originally created and published by Medical Device Network, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Sign in to access your portfolio
Associated Press
24-03-2025
- Business
- Associated Press
Aditxt Subsidiary Pearsanta Completes the Acquisition of Proprietary Adductomics Technology to Develop and Advance the Platform Toward Clinical and Commercial Applications for Monitoring Early Signs of Increased Cancer Risk
MOUNTAIN VIEW, Calif.--(BUSINESS WIRE)--Mar 24, 2025-- Aditxt, Inc. (NASDAQ: ADTX) ('Aditxt' or the 'Company'), a social innovation platform accelerating promising health innovations, today announced that its subsidiary, Pearsanta, Inc. ('Pearsanta'), has acquired key patents related to adductomics-based DNA damage detection, which it believes will further strengthen its position in the cancer prevention-focused diagnostic industry. Pearsanta acquired the patents in exchange for the issuance of Pearsanta Convertible Preferred Stock in a transaction valued at approximately $1 million. Over the next two to three years, Pearsanta will seek to advance clinical validation, regulatory submissions, and commercialization efforts to integrate this technology into its diagnostic portfolio. The acquisition aligns with Pearsanta's mission to advance early cancer detection and prevention that is globally accessible. Mitomic ® Technology, Pearsanta's proprietary platform, uses mitochondrial DNA biomarkers designed for non-invasive cancer detection. With the addition of adductomics-based DNA damage analysis, Pearsanta is expanding its capabilities to assess carcinogen exposure and genomic instability before permanent mutations occur, reinforcing its commitment to proactive cancer risk assessment. Enhancing Early Cancer Detection with Adductomics The acquired patents cover proprietary advancements in DNA adduct detection and analysis, providing the capability to assess genomic instability caused by environmental toxins and metabolic byproducts. DNA adducts—chemical modifications to DNA nucleotides caused by carcinogens—are among the earliest detectable indicators of cancer risk. Pearsanta intends to develop this platform into a comprehensive, panoramic assessment tool for DNA adducts, utilizing urine, blood or solid tissue samples to provide actionable insights into DNA damage before mutations occur. This approach has the potential to identify environmental or biological factors contributing to cancer risk, offering earlier intervention strategies for individuals at elevated risk. Advancing Toward Commercialization Pearsanta is advancing a strategic development plan to bring adductomics-based diagnostics to market, focusing on: Clinical validation to confirm the technology's effectiveness in assessing cancer risk. Regulatory submissions to support integration into Laboratory Developed Tests (LDTs) and future FDA pathways. Scalability within CLIA/CAP-certified laboratories, seeking to ensure clinical access and, ultimately, commercial adoption. Over the next two to three years, Pearsanta aims to incorporate adductomics-based screening into its expanding portfolio of precision oncology solutions, reinforcing its commitment to shifting cancer diagnostics from late-stage detection to proactive prevention. Pearsanta's Role in the Future of Cancer Prevention Current cancer diagnostics predominantly detect tumors after they have developed, leaving patients with limited treatment options that are often costly and less effective. Pearsanta's approach, strengthened by the acquisition of adductomics technology, represents a new frontier in cancer prevention, potentially facilitating identification of DNA damage at its earliest molecular stages—before irreversible mutations occur. 'We envision a world where cancer risk can be assessed before symptoms appear, giving patients and physicians the opportunity to intervene when it matters most,' said Chris Mitton, President of Pearsanta. 'We believe that Pearsanta is uniquely positioned to shift cancer care from reactive treatment to proactive prevention. This advancement has the potential to redefine cancer care by enabling earlier risk assessment, allowing individuals to adjust lifestyle factors, reduce exposure to carcinogens and adopt personalized prevention strategies. In underserved regions, where access to oncology treatments remains limited, we believe that adductomics-based screening could provide a cost-effective tool for early cancer risk assessment, empowering preventive measures when they are most effective.' Additionally, by detecting DNA damage before disease progression, this technology has the potential to lower the overall economic burden of cancer, reducing the reliance on late-stage treatments and hospitalizations. 'Pearsanta's acquisition reflects Aditxt's commitment to driving innovation with the potential of addressing some of the most pressing health challenges such as cancer,' said Amro Albanna, Co-Founder, Chairman, and CEO of Aditxt. 'We believe that this technology has the potential to redefine how we assess and mitigate cancer risk, which could reshape the future of early detection and prevention of cancer.' About Pearsanta Pearsanta is at the forefront of precision health, focusing on early cancer detection through advanced diagnostic technologies. Its proprietary Mitomic Technology Platform leverages the unique properties of mitochondrial DNA to detect cancer and other diseases with high accuracy via non-invasive, blood-based liquid biopsy tests. Pearsanta's asset portfolio also includes a range of other innovative diagnostic technologies, all aimed at transforming early disease detection and monitoring, enabling more informed treatment decisions and ultimately improving patient outcomes. For more information, please visit About Aditxt Aditxt, Inc. ® is a social innovation platform dedicated to accelerating promising health innovations. Aditxt's ecosystem of research institutions, industry partners, and shareholders collaboratively drives its mission to 'Make Promising Innovations Possible Together.' The innovation platform is the cornerstone of Aditxt's strategy, where multiple disciplines drive disruptive growth and address significant societal challenges. Aditxt operates a unique model that democratizes innovation, ensures every stakeholder's voice is heard and valued, and empowers collective progress. Aditxt currently operates two programs focused on immune health and precision health. The Company plans to introduce two additional programs dedicated to public health and women's health. For these, Aditxt has entered into an Arrangement Agreement with Appili Therapeutics, Inc. ('Appili') (TSX: APLI; OTCPink: APLIF), which focuses on infectious diseases, and a Merger Agreement with Evofem Biosciences, Inc. ('Evofem') (OTCQB: EVFM). Each program will be designed to function autonomously while collectively advancing Aditxt's mission of discovering, developing and deploying innovative health solutions to tackle some of the most urgent health challenges. The closing of each of the transactions with Appili and Evofem is subject to several conditions, including but not limited to approval of the transactions by the respective target shareholders and Aditxt raising sufficient capital to fund its obligations at closing. These obligations include cash payments of approximately $17 million for Appili and $17 million for Evofem, which includes approximately $15.2 million required to satisfy Evofem's senior secured noteholder; should Aditxt fail to secure these funds, Evofem's senior secured noteholder is expected to seek to prevent the closing of the merger with Evofem. On Dec. 23, 2024, Evofem announced the cancellation of its special stockholders meeting and the withdrawal of the merger proposal with Aditxt from consideration by the stockholders. No assurance can be provided that all of the conditions to closing will be obtained or satisfied or that either of the transactions will ultimately close. Forward-Looking Statements Certain statements in this press release constitute 'forward-looking statements' within the meaning of federal securities laws. Forward-looking statements include statements regarding the Company's intentions, beliefs, projections, outlook, analyses, or current expectations concerning, among other things, the Company's ongoing and planned product and business development; the Company's ability to finance and execute its strategic M&A initiatives; the Company's ability to obtain the necessary funding and partner to commence clinical trials; the Company's intellectual property position; the Company's ability to develop commercial functions; expectations regarding product launch and revenue; the Company's results of operations, cash needs, spending, financial condition, liquidity, prospects, growth, and strategies; the Company's ability to raise additional capital; expected usage of the Company's ELOC and ATM facilities; the industry in which the Company operates; and the trends that may affect the industry or the Company. Forward-looking statements are not guarantees of future performance, and actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors, as well as market and other conditions and those risks more fully discussed in the section titled 'Risk Factors' in Aditxt's most recent Annual Report on Form 10-K, as well as discussions of potential risks, uncertainties, and other important factors in the Company's other filings with the Securities and Exchange Commission. All such statements speak only as of the date made, and the Company undertakes no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law. Corporate Communications Jeff Ramson, PCG Advisory, Inc. T: 646-863-6893 SOURCE: Aditxt, Inc. Copyright Business Wire 2025. PUB: 03/24/2025 08:15 AM/DISC: 03/24/2025 08:15 AM
Yahoo
24-02-2025
- Business
- Yahoo
Aditxt subsidiary Persanta engages Dominary Securities for IPO
The company states: 'Aditxt (ADTX) announced that its subsidiary, Pearsanta has engaged Dominari Securities LLC as lead underwriter for Pearsanta's planned initial public offering. The proposed IPO, advised by Dominari Securities, is intended to support Pearsanta's U.S. and international commercial launch efforts and further advance its Mitomic(R) Technology platform for early cancer detection and diagnosis. Pearsanta is developing a non-invasive blood-based test designed to detect cancer at earlier stages when treatment outcomes are more favorable. The Company's proprietary Mitomic(R) Technology leverages mitochondrial DNA deletions as biomarkers for disease detection, providing a unique approach to identifying malignancies. We believe that Pearsanta's biomarker portfolio covers many high-clinical need cancers, with potential applications outside oncology. As Pearsanta prepares for its planned IPO targeted for the second half of 2025, the Company is focused on advancing its commercialization strategy. IPO proceeds are intended to be used to fund the U.S. launch of its Laboratory Developed Tests (LDTs) for early cancer detection and drive global commercialization through distribution partnerships and key international regulatory approvals.' See what stocks are receiving strong buy ratings from top-rated analysts. Filter, analyze, and streamline your search for investment opportunities with TipRanks' Stock Screener. Published first on TheFly – the ultimate source for real-time, market-moving breaking financial news. Try Now>> See today's best-performing stocks on TipRanks >> Read More on ADTX: Biotech Alert: Searches spiking for these stocks today Aditxt, Inc. Plans IPO for Pearsanta in 2025 Aditxt to explore taking Pearsanta subsidiary public Sign in to access your portfolio
