Latest news with #Products
Yahoo
15 hours ago
- Business
- Yahoo
Knight Therapeutics and Sumitomo Pharma enter into Exclusive Licensing Agreements to commercialize Sumitomo's Canadian Portfolio
MONTREAL and MARLBOROUGH, Mass., June 05, 2025 (GLOBE NEWSWIRE) -- Knight Therapeutics Inc. (TSX: GUD) ("Knight"), a pan-American (ex-USA) specialty pharmaceutical company, and Sumitomo Pharma America Inc. ('SMPA') announced today that Knight and SMPA's affiliates have entered into exclusive license and supply agreements to commercialize MYFEMBREE® (relugolix/estradiol/norethindrone acetate), ORGOVYX® (relugolix) and vibegron in Canada, as well as an asset purchase agreement under which Knight will acquire certain mature products (the 'Mature Products', together with MYFEMBREE®, ORGOVYX® and vibegron, the 'Products'). For the year ended March 2025, the Products generated C$11.2 million in revenue. Under the terms of the agreements, Knight will have the exclusive rights to distribute, promote, market and sell the Products in Canada. Knight will begin commercial activities following a transition period from Sumitomo Pharma Canada. The consideration for the transaction includes an upfront amount of C$25.4 million and Knight may pay future contingent payments of up to C$15.75 million upon achieving certain sales milestones. In addition, Knight is expected to pay an estimated C$7 million for inventory to be acquired over the next eight months. 'We are pleased that Knight will continue to bring this suite of products to patients and health care providers throughout Canada,' said Tsutomu Nakagawa, Ph.D., President and Chief Executive Officer of SMPA. 'This divestiture is aligned with our long-term strategy to focus on and grow our core brands in the U.S. and to accelerate commercialization of our pipeline assets for oncology, regenerative medicine and cell therapy.' 'This transaction is another great example of our continued execution on our growth strategy of building a portfolio of innovative products,' said Samira Sakhia, President and Chief Executive Officer of Knight Therapeutics Inc. 'MYFEMBREE®, ORGOVYX® and vibegron are highly synergistic with our current Canadian business in women's health with IMVEXXY® and BIJUVA®, as well as in urology and prostate cancer with TRELSTAR®. We look forward to expanding access to these innovative therapies to patients and healthcare providers.'Conference Call Notice Knight will host a conference call and audio webcast to discuss the acquisition on Thursday, June 5, 2025, at 8:30 am ET. Knight cordially invites all interested parties to participate in this call. Date: Thursday, June 5, 2025Time: 8:30 a.m. ETTelephone: Toll Free 1-888-699-1199 or International 1-416-945-7677Webcast: or WebcastThis is a listen-only audio webcast. Media Player is required to listen to the broadcast. Replay: An archived replay will be available for 30 days at About MYFEMBREE® MYFEMBREE® (relugolix 40 mg, estradiol 1 mg, and norethindrone acetate 0.5 mg tablets) was approved by Health Canada in September 2023 making it the first oral prescription treatment for both the management of heavy menstrual bleeding associated with uterine fibroids and for the management of moderate to severe pain associated with endometriosis in pre-menopausal women. According to IQVIA, sales of MYFEMBREE® in Canada were approximately C$2.9 million in 2024. About ORGOVYX® (relugolix) ORGOVYX® (relugolix 120mg tablets) is the first and only oral gonadotropin-releasing hormone (GnRH) receptor antagonist approved by Health Canada in October 2023 for the treatment of adult patients with advanced prostate cancer. As a GnRH antagonist, ORGOVYX® blocks the pituitary GnRH receptor, thereby reducing the release of the luteinizing and follicle-stimulating hormones, and consequently reducing the production of testicular testosterone, a hormone known to stimulate the growth of prostate cancer. According to IQVIA, sales of ORGOVYX® in Canada were approximately C$1.2 million in 2024. About Vibegron In the U.S., vibegron 75mg tablets (tradename GEMTESA®) has been indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults since April 2021. Vibegron works by selectively targeting β3 adrenergic receptors to reduce OAB symptoms through the relaxation of the bladder detrusor muscle to increase bladder capacity. About Knight Therapeutics Inc. Knight Therapeutics Inc., headquartered in Montreal, Canada, is a specialty pharmaceutical company focused on acquiring or in-licensing and commercializing pharmaceutical products for Canada and Latin America. Knight's Latin American subsidiaries operate under United Medical, Biotoscana Farma and Laboratorio LKM. Knight Therapeutics Inc.'s shares trade on TSX under the symbol GUD. For more information about Knight Therapeutics Inc., please visit the company's web site at or Forward-Looking Statement This document contains forward-looking statements for Knight Therapeutics Inc. and its subsidiaries. These forward-looking statements, by their nature, necessarily involve risks and uncertainties that could cause actual results to differ materially from those contemplated by the forward-looking statements. Knight Therapeutics Inc. considers the assumptions on which these forward-looking statements are based to be reasonable at the time they were prepared but cautions the reader that these assumptions regarding future events, many of which are beyond the control of Knight Therapeutics Inc. and its subsidiaries, may ultimately prove to be incorrect. Factors and risks which could cause actual results to differ materially from current expectations are discussed in Knight Therapeutics Inc.'s Annual Report and in Knight Therapeutics Inc.'s Annual Information Form for the year ended December 31, 2024, as filed on Knight Therapeutics Inc. disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information or future events, except as required by law. About Sumitomo Pharma Sumitomo Pharma Co., Ltd., is a global pharmaceutical company based in Japan with key operations in the U.S. (Sumitomo Pharma America, Inc.), Canada (Sumitomo Pharma Canada, Inc.), and Europe (Sumitomo Pharma Switzerland GmbH) focused on addressing patient needs in oncology, urology, women's health, rare diseases, psychiatry & neurology, and cell & gene therapies. With several marketed products in the U.S., Canada, and Europe, a diverse pipeline of early- to late-stage assets, we aim to accelerate discovery, research, and development to bring novel therapies to patients sooner. For more information on SMPA, visit our website or follow us on LinkedIn. SUMITOMO PHARMA is a trademark of Sumitomo Pharma Co., Ltd., used under license. SUMITOMO is a registered trademark of Sumitomo Chemical Co., Ltd., used under license. Sumitomo Pharma America, Inc. is a U.S. subsidiary of Sumitomo Pharma Co., Ltd. GEMTESA, MYFEMBREE and ORGOVYX are trademarks of Sumitomo Pharma Switzerland GmbH. For more information:Investor Contact for Knight Therapeutics Inc.: Knight Therapeutics Inc. Samira Sakhia Arvind Utchanah President & Chief Executive Officer Chief Financial Officer T: 514.484.4483 T. +598.2626.2344 F: 514.481.4116 Email: IR@ Email: IR@ Website: Website: For SMPA Thomas HillVice President, Head of Corporate Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Daily Mail
2 days ago
- Business
- Daily Mail
Meghan Markle issues shock update about As Ever products
Meghan Markle has issued a shock update about her As Ever products. The entrepreneur, 43, took to Instagram to share the update about her lifestyle venture on her official business page. Alongside a snapshot of bowls of strawberries resting on a kitchen countertop, she wrote: 'To all who've been wondering and waiting, thank you! 'Your favorites are returning, plus a few NEW things we can't wait to show you. Coming this month... get excited!' The As Ever range went on sale last month and products sold out within half an hour of going live. Meghan's first line of products included raspberry spread, honey, herbal tea and ready made crepe mix.
Yahoo
22-05-2025
- Business
- Yahoo
AI Meets Genomics: Predictive Oncology Breakthrough Coincides with Regeneron's $256M 23andMe Acquisition
Company Leverages More Than Twenty Years of Drug Response Data Derived from Massive Biobank of Live Cell Tumor Samples PITTSBURGH, May 22, 2025 (GLOBE NEWSWIRE) -- Predictive Oncology Inc. (NASDAQ: POAI) moves to leverage its vast biobank of more than 150,000 heterogenous live cell tumor samples and drug response data to aggressively pursue novel drug discovery, biomarker discovery and drug repurposing using AI and machine learning. Earlier this week, Regeneron Pharmaceuticals announced its acquisition of 23andMe for $256 million, marking a strategic step in the industry-wide shift toward data-driven drug discovery. The move highlights the enduring value of 23andMe's vast genomic database and its proven track record in therapeutic development partnerships. 23andMe houses one of the world's largest and most comprehensive longitudinal genomic datasets, with many customers having consented to ongoing health tracking. This unique trove of real-world health data offers powerful insights into disease progression, treatment efficacy, and patient stratification—making it a highly valuable resource for precision drug development. A testament to this value is 23andMe's previous $300 million partnership with GlaxoSmithKline (GSK) in 2018, which was later extended in an all-cash deal. The continuation signaled strong confidence in the utility of 23andMe's data to inform drug discovery efforts and guide clinical decisions. With this acquisition, Regeneron is expected to integrate 23andMe's consumer genomic and health data into its own R&D pipeline. The company aims to strengthen its capabilities in areas such as target identification, biomarker discovery, and clinical trial optimization, aligning with a broader trend across the biopharma landscape: the convergence of artificial intelligence, real-world data, and predictive analytics to improve therapeutic outcomes. At the forefront of this transformation stands Predictive Oncology. 'We recently achieved a major milestone in AI-enabled cancer drug discovery,' said Raymond Vennare, Chairman and Chief Executive Officer of Predictive Oncology. 'Using compounds sourced from the Natural Products Discovery Core at the University of Michigan, we successfully developed predictive tumor response models for 21 previously untested molecules. These models are targeted at some of the most common cancer types, including breast, colon, and ovarian cancers. 'What makes this advancement particularly significant is that these compounds had no prior response data—making this a clear demonstration of AI's ability not just to enhance but to lead in early-stage drug discovery. Predictive Oncology's proprietary active machine learning platform was able to model tumor response across diverse cancer types using insights derived from its biobank of over 150,000 tumor samples spanning 137 cancer indications.' The combination of artificial intelligence, machine learning and empirical validation allows the company to test drug response in silico before confirming them in vitro in their CLIA laboratory, which has been proven to dramatically accelerate timelines and improve the Probability of Technical Success (PTS) in drug development. 'Our ability to combine artificial intelligence and machine learning with live cell tumor samples and real-world drug response data allows us to expedite early-stage drug discovery and de-risk downstream drug development. This strategic first-mover advantage enables our partners to accelerate timelines, reduce R&D risk, and maximize ROI. This proprietary AI/ML platform and robust scientific methodology is the cornerstone of our business development efforts in oncology drug discovery and repurposing,' Mr. Vennare concluded. Not unlike Regeneron's acquisition of 23andMe, Predictive Oncology's AI-driven breakthroughs reflect a broader transformation in life sciences. The integration of genomics, machine learning, and real-world biological data is no longer an emerging trend—it's now a foundational force driving the future of precision medicine. About Predictive OncologyPredictive Oncology is on the cutting edge of the rapidly growing use of artificial intelligence and machine learning to expedite early drug discovery and enable drug development for the benefit of cancer patients worldwide. The company's scientifically validated AI platform, PEDAL, is able to predict with 92% accuracy if a tumor sample will respond to a certain drug compound, allowing for a more informed selection of drug/tumor type combinations for subsequent in-vitro testing. Together with the company's vast biobank of more than 150,000 assay-capable heterogenous human tumor samples, Predictive Oncology offers its academic and industry partners one of the industry's broadest AI-based drug discovery solutions, further complimented by its wholly owned CLIA laboratory facility. Predictive Oncology is headquartered in Pittsburgh, PA. Investor Relations Contact: Mike MoyerLifeSci Advisors, LLCmmoyer@ Forward-Looking Statements Certain statements made in this press release are 'forward-looking statements' within the meaning of the 'safe harbor' provisions of the Private Securities Litigation Reform Act of 1995. These forward- looking statements reflect Predictive Oncology's current expectations and projections about future events and are subject to substantial risks, uncertainties and assumptions about Predictive Oncology's operations and the investments Predictive Oncology makes. All statements, other than statements of historical facts, included in this press release regarding our strategy, future operations, future financial position, future revenue and financial performance, projected costs, prospects, changes in management, plans and objectives of management are forward-looking statements. The words 'anticipate,' 'believe,' 'estimate,' 'expect,' 'intend,' 'may,' 'plan,' 'would,' 'target' and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Predictive Oncology's actual future performance may materially differ from that contemplated by the forward-looking statements as a result of a variety of factors including, among other things, factors discussed under the heading 'Risk Factors' in Predictive Oncology's filings with the SEC. Except as expressly required by law, Predictive Oncology disclaims any intent or obligation to update these forward-looking statements. Predictive Oncology does not give any assurance that Predictive Oncology will achieve its expectations described in this press release.
Yahoo
22-05-2025
- Business
- Yahoo
AI Meets Genomics: Predictive Oncology Breakthrough Coincides with Regeneron's $256M 23andMe Acquisition
Company Leverages More Than Twenty Years of Drug Response Data Derived from Massive Biobank of Live Cell Tumor Samples PITTSBURGH, May 22, 2025 (GLOBE NEWSWIRE) -- Predictive Oncology Inc. (NASDAQ: POAI) moves to leverage its vast biobank of more than 150,000 heterogenous live cell tumor samples and drug response data to aggressively pursue novel drug discovery, biomarker discovery and drug repurposing using AI and machine learning. Earlier this week, Regeneron Pharmaceuticals announced its acquisition of 23andMe for $256 million, marking a strategic step in the industry-wide shift toward data-driven drug discovery. The move highlights the enduring value of 23andMe's vast genomic database and its proven track record in therapeutic development partnerships. 23andMe houses one of the world's largest and most comprehensive longitudinal genomic datasets, with many customers having consented to ongoing health tracking. This unique trove of real-world health data offers powerful insights into disease progression, treatment efficacy, and patient stratification—making it a highly valuable resource for precision drug development. A testament to this value is 23andMe's previous $300 million partnership with GlaxoSmithKline (GSK) in 2018, which was later extended in an all-cash deal. The continuation signaled strong confidence in the utility of 23andMe's data to inform drug discovery efforts and guide clinical decisions. With this acquisition, Regeneron is expected to integrate 23andMe's consumer genomic and health data into its own R&D pipeline. The company aims to strengthen its capabilities in areas such as target identification, biomarker discovery, and clinical trial optimization, aligning with a broader trend across the biopharma landscape: the convergence of artificial intelligence, real-world data, and predictive analytics to improve therapeutic outcomes. At the forefront of this transformation stands Predictive Oncology. 'We recently achieved a major milestone in AI-enabled cancer drug discovery,' said Raymond Vennare, Chairman and Chief Executive Officer of Predictive Oncology. 'Using compounds sourced from the Natural Products Discovery Core at the University of Michigan, we successfully developed predictive tumor response models for 21 previously untested molecules. These models are targeted at some of the most common cancer types, including breast, colon, and ovarian cancers. 'What makes this advancement particularly significant is that these compounds had no prior response data—making this a clear demonstration of AI's ability not just to enhance but to lead in early-stage drug discovery. Predictive Oncology's proprietary active machine learning platform was able to model tumor response across diverse cancer types using insights derived from its biobank of over 150,000 tumor samples spanning 137 cancer indications.' The combination of artificial intelligence, machine learning and empirical validation allows the company to test drug response in silico before confirming them in vitro in their CLIA laboratory, which has been proven to dramatically accelerate timelines and improve the Probability of Technical Success (PTS) in drug development. 'Our ability to combine artificial intelligence and machine learning with live cell tumor samples and real-world drug response data allows us to expedite early-stage drug discovery and de-risk downstream drug development. This strategic first-mover advantage enables our partners to accelerate timelines, reduce R&D risk, and maximize ROI. This proprietary AI/ML platform and robust scientific methodology is the cornerstone of our business development efforts in oncology drug discovery and repurposing,' Mr. Vennare concluded. Not unlike Regeneron's acquisition of 23andMe, Predictive Oncology's AI-driven breakthroughs reflect a broader transformation in life sciences. The integration of genomics, machine learning, and real-world biological data is no longer an emerging trend—it's now a foundational force driving the future of precision medicine. About Predictive OncologyPredictive Oncology is on the cutting edge of the rapidly growing use of artificial intelligence and machine learning to expedite early drug discovery and enable drug development for the benefit of cancer patients worldwide. The company's scientifically validated AI platform, PEDAL, is able to predict with 92% accuracy if a tumor sample will respond to a certain drug compound, allowing for a more informed selection of drug/tumor type combinations for subsequent in-vitro testing. Together with the company's vast biobank of more than 150,000 assay-capable heterogenous human tumor samples, Predictive Oncology offers its academic and industry partners one of the industry's broadest AI-based drug discovery solutions, further complimented by its wholly owned CLIA laboratory facility. Predictive Oncology is headquartered in Pittsburgh, PA. Investor Relations Contact: Mike MoyerLifeSci Advisors, LLCmmoyer@ Forward-Looking Statements Certain statements made in this press release are 'forward-looking statements' within the meaning of the 'safe harbor' provisions of the Private Securities Litigation Reform Act of 1995. These forward- looking statements reflect Predictive Oncology's current expectations and projections about future events and are subject to substantial risks, uncertainties and assumptions about Predictive Oncology's operations and the investments Predictive Oncology makes. All statements, other than statements of historical facts, included in this press release regarding our strategy, future operations, future financial position, future revenue and financial performance, projected costs, prospects, changes in management, plans and objectives of management are forward-looking statements. The words 'anticipate,' 'believe,' 'estimate,' 'expect,' 'intend,' 'may,' 'plan,' 'would,' 'target' and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Predictive Oncology's actual future performance may materially differ from that contemplated by the forward-looking statements as a result of a variety of factors including, among other things, factors discussed under the heading 'Risk Factors' in Predictive Oncology's filings with the SEC. Except as expressly required by law, Predictive Oncology disclaims any intent or obligation to update these forward-looking statements. Predictive Oncology does not give any assurance that Predictive Oncology will achieve its expectations described in this press in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
15-05-2025
- Business
- Yahoo
TriSalus Life Sciences, Inc. (TLSI) Reports Q1 Loss, Lags Revenue Estimates
TriSalus Life Sciences, Inc. (TLSI) came out with a quarterly loss of $0.33 per share versus the Zacks Consensus Estimate of a loss of $0.20. This compares to loss of $0.54 per share a year ago. These figures are adjusted for non-recurring items. This quarterly report represents an earnings surprise of -65%. A quarter ago, it was expected that this company would post a loss of $0.35 per share when it actually produced a loss of $0.35, delivering no surprise. Over the last four quarters, the company has not been able to surpass consensus EPS estimates. TriSalus Life Sciences, Inc. , which belongs to the Zacks Medical - Products industry, posted revenues of $9.17 million for the quarter ended March 2025, missing the Zacks Consensus Estimate by 1.04%. This compares to year-ago revenues of $6.46 million. The company has topped consensus revenue estimates just once over the last four quarters. The sustainability of the stock's immediate price movement based on the recently-released numbers and future earnings expectations will mostly depend on management's commentary on the earnings call. TriSalus Life Sciences, Inc. Shares have lost about 2.2% since the beginning of the year versus the S&P 500's gain of 0.2%. While TriSalus Life Sciences, Inc. Has underperformed the market so far this year, the question that comes to investors' minds is: what's next for the stock? There are no easy answers to this key question, but one reliable measure that can help investors address this is the company's earnings outlook. Not only does this include current consensus earnings expectations for the coming quarter(s), but also how these expectations have changed lately. Empirical research shows a strong correlation between near-term stock movements and trends in earnings estimate revisions. Investors can track such revisions by themselves or rely on a tried-and-tested rating tool like the Zacks Rank, which has an impressive track record of harnessing the power of earnings estimate revisions. Ahead of this earnings release, the estimate revisions trend for TriSalus Life Sciences, Inc. Mixed. While the magnitude and direction of estimate revisions could change following the company's just-released earnings report, the current status translates into a Zacks Rank #3 (Hold) for the stock. So, the shares are expected to perform in line with the market in the near future. You can see the complete list of today's Zacks #1 Rank (Strong Buy) stocks here. It will be interesting to see how estimates for the coming quarters and current fiscal year change in the days ahead. The current consensus EPS estimate is -$0.17 on $10.69 million in revenues for the coming quarter and -$0.60 on $44.3 million in revenues for the current fiscal year. Investors should be mindful of the fact that the outlook for the industry can have a material impact on the performance of the stock as well. In terms of the Zacks Industry Rank, Medical - Products is currently in the bottom 28% of the 250 plus Zacks industries. Our research shows that the top 50% of the Zacks-ranked industries outperform the bottom 50% by a factor of more than 2 to 1. One other stock from the same industry, Canopy Growth Corporation (CGC), is yet to report results for the quarter ended March 2025. This company is expected to post quarterly loss of $0.28 per share in its upcoming report, which represents no change from the year-ago quarter. The consensus EPS estimate for the quarter has remained unchanged over the last 30 days. Canopy Growth Corporation's revenues are expected to be $49.92 million, down 7.5% from the year-ago quarter. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report TriSalus Life Sciences, Inc. (TLSI) : Free Stock Analysis Report Canopy Growth Corporation (CGC) : Free Stock Analysis Report This article originally published on Zacks Investment Research ( Zacks Investment Research Sign in to access your portfolio
