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Yahoo
3 days ago
- Health
- Yahoo
Misophonia Has Genetic Links to Depression And Anxiety, Study Finds
Most of us can relate to feeling uncomfortable when someone scrapes their nails down a chalkboard. For those suffering the condition misophonia, sounds like slurping, snoring, breathing, and chewing and draw an equally stressful response. A study published in 2023 by researchers in the Netherlands suggests the condition shares genes with mood disorders such as anxiety, depression, and PTSD. University of Amsterdam psychiatrist Dirk Smit and colleagues analyzed the genetic data from the Psychiatric Genomics Consortium, UK Biobank, and 23andMe databases and found people who self-identified as having misophonia were more likely to have genes associated with psychiatric disorders, as well as tinnitus. Watch the clip below for a summary on their findings. Patients with tinnitus – a persistent, shrill ringing in the ears – are also more likely to have psychological symptoms of depression and anxiety. "There was also an overlap with PTSD genetics," Smit told Eric W. Dolan at PsyPost. "This means that genes that give a sensitivity to PTSD also increase the likelihood for misophonia, and that could point to a shared neurobiological system that affects both. And that could suggest that treatment techniques used for PTSD could also be used for misophonia." This doesn't mean misophonia and these other conditions necessarily have shared mechanisms, only that some of the genetic risk factors may be similar. Previous research found people who experience misophonia are more likely to internalize their distress. Smit and team's research, published in 2023, also backed this up, showing strong links with personality traits such as worry, guilt, loneliness, and neuroticism. Responses to a triggering sound can range from irritation and anger to distress that interferes with everyday life. "It has been argued… that misophonia is based on the feelings of guilt about the evoked irritation and anger rather than behavioral expressions of anger itself that causes the distress," write Smit and team. People with autism spectrum disorder ( ASD) were less likely to experience misophonia. This was unexpected as those with ASD have a decreased tolerance to sounds. "Our results suggest that misophonia and ASD are relatively independent disorders with regard to genomic variation," the researchers write in their paper. "It raises the possibility that other forms of misophonia exist, one that is mostly driven by conditioning of anger or other negative emotionality to specific trigger sounds moderated by personality traits." Smit and colleagues caution their data was mostly European so the same links may not show up in different populations. What's more, misophonia was not medically diagnosed in their data samples, only self-reported which may also skew the results. But their study also provides clues for where further research could focus to find the biological mechanism behind misophonia. A 2023 survey suggests misophonia is more prevalent than previously thought, making studies like this one invaluable for understanding how our perception of the world links with our mind's ability to cope within it. This research was published in Frontiers in Neuroscience. An earlier version of this article was published in October 2024. Experimental Drug Helped Cancer Patients Live 40% Longer in Clinical Trial Leprosy Was Lurking in The Americas Long Before Colonization, Study Finds Does Retinol Reverse Signs of Aging? Here's The Science.
Saba Yemen
19-02-2025
- Health
- Saba Yemen
Study: Phonophobia linked to genetic factors
Amsterdam - Saba: A recent study has shown that the hatred of sounds that some people suffer from is linked to genetic factors such as anxiety and depression, and that those with this condition were more likely to have genes linked to psychological disorders as well as tinnitus. The study, published in the journal "Neurology" Frontiers in Neuroscience, says that while most people can feel uncomfortable when someone scrapes their nails on a chalkboard, those who suffer from hatred of sounds can have an equally strong reaction to sounds such as sipping, snoring, breathing and chewing. The survey conducted in 2023 suggests that hatred of sounds is more widespread than previously thought, and research from Europe suggests that this condition shares genes with anxiety, depression and post-traumatic stress disorder. University of Amsterdam psychiatrist Dirk Smit and colleagues analyzed genetic data from the Psychiatric Genomics Consortium, the UK Biobank, and the 23andMe databases, and found that people who identified themselves as having phonophobia were more likely to have genes linked to psychiatric disorders as well as tinnitus. Patients with tinnitus — a persistent, intense ringing in the ears — were also more likely to have psychiatric symptoms such as depression and anxiety. "There was also overlap with PTSD genes," Smit told Eric W. Dolan at PsyPost. 'This means that genes that confer susceptibility to PTSD also increase the likelihood of developing phonophobia, and this may suggest a common neurobiological system that affects both. This may suggest that treatment techniques used for PTSD could also be used to treat phonophobia." This doesn't necessarily mean that phonophobia and other illnesses have common mechanisms, just that some of the genetic risk factors may be similar. Previous research has found that people with aversion to sound are more likely to internalize their distress. Research by Smith and his team, published in 2023, also backed this up, showing strong links with personality traits such as anxiety, guilt, loneliness, and neuroticism. 'Responses to a triggering sound can range from annoyance and anger to distress that interferes with daily life… It has been suggested that… voice hatred is based on feelings of guilt over the triggered annoyance and anger rather than on behavioral expressions of the anger itself that cause distress,' Smith and his team wrote. People with autism spectrum disorder (ASD) were less likely to develop voice hatred. This was unexpected because people with ASD have a lower tolerance for voices. The study results suggest that voice hatred and ASD are relatively independent disorders with respect to genetic variation,' the researchers wrote in their paper. "This raises the possibility that there are other forms of voice hatred, one that is often triggered by conditioning anger or other negative emotions to specific sounds that are modified by personality traits." Smit and his colleagues caution that their data were mostly European, so the same associations may not be seen in different populations. Furthermore, voice hatred was not diagnosed medically in the data samples they obtained, but was self-reported. Only self-reported, which could also distort the results. But their study also provides clues about where further research could focus to find the biological mechanism behind voice hatred. Whatsapp Telegram Email Print more of (Press)
Yahoo
17-02-2025
- Health
- Yahoo
Misophonia Has Genetic Links to Anxiety And Depression, Study Finds
While most people can relate to feeling uncomfortable when someone scrapes their nails down a chalkboard, those suffering from misophonia can have an equally intense reaction to sounds like slurping, snoring, breathing, and chewing. A 2023 survey suggests misophonia is more prevalent than previously thought, and research from Europe suggests this condition shares genes with anxiety, depression, and PTSD. University of Amsterdam psychiatrist Dirk Smit and colleagues analyzed the genetic data from the Psychiatric Genomics Consortium, UK Biobank, and 23andMe databases and found people who self-identified as having misophonia were more likely to have genes associated with psychiatric disorders as well as tinnitus. Patients with tinnitus – a persistent, shrill ringing in the ears – are also more likely to have psychological symptoms of depression and anxiety. "There was also an overlap with PTSD genetics," Smit told Eric W. Dolan at PsyPost. "This means that genes that give a sensitivity to PTSD also increase the likelihood for misophonia, and that could point to a shared neurobiological system that affects both. And that could suggest that treatment techniques used for PTSD could also be used for misophonia." This doesn't mean misophonia and these other conditions necessarily have shared mechanisms, only that some of the genetic risk factors may be similar. Previous research found people who experience misophonia are more likely to internalize their distress. Smit and team's research, published in 2023, also backed this up, showing strong links with personality traits such as worry, guilt, loneliness, and neuroticism. Responses to a triggering sound can range from irritation and anger to distress that interferes with everyday life. "It has been argued… that misophonia is based on the feelings of guilt about the evoked irritation and anger rather than behavioral expressions of anger itself that causes the distress," write Smit and team. People with autism spectrum disorder ( ASD) were less likely to experience misophonia. This was unexpected as those with ASD have a decreased tolerance to sounds. "Our results suggest that misophonia and ASD are relatively independent disorders with regard to genomic variation," the researchers write in their paper. "It raises the possibility that other forms of misophonia exist, one that is mostly driven by conditioning of anger or other negative emotionality to specific trigger sounds moderated by personality traits." Smit and colleagues caution their data was mostly European so the same links may not show up in different populations. What's more, misophonia was not medically diagnosed in their data samples, only self-reported which may also skew the results. But their study also provides clues for where further research could focus to find the biological mechanism behind misophonia. This research was published in Frontiers in Neuroscience. An earlier version of this article was published in October 2024. Man's Carnivore Diet Causes Strange Yellow Deposits on Skin Video Game Has 80% Success Rate in Identifying Autistic Kids Your Risk of Cancer Could Fluctuate Even Before You're Born
