Latest news with #TimRebbeck
Global News
09-05-2025
- Health
- Global News
Which cancers are increasing in younger adults? A new study has answers
Cancer before age 50 is rare, but increasing, in the United States and researchers want to know why. A new government study provides the most complete picture yet of early-onset cancers, finding that the largest increases are in breast, colorectal, kidney and uterine cancers. Scientists from the National Cancer Institute looked at data that included more than two million cancers diagnosed in people 15 to 49 years old between 2010 and 2019. Of 33 cancer types, 14 cancers had increasing rates in at least one younger age group. About 63 per cent of the early-onset cancers were among women. 1:46 Call for colon cancer screening age to be lowered after late terminal diagnosis 'These kinds of patterns generally reflect something profound going on,' said Tim Rebbeck of Dana-Farber Cancer Institute, who studies cancer risk and was not involved in the research. 'We need to fund research that will help us understand.' Story continues below advertisement The findings were published Thursday in Cancer Discovery, a journal of the American Association for Cancer Research. How many extra cancers are we talking about? The researchers compared cancer rates in 2019 to what would be expected based on 2010 rates. Get breaking National news For news impacting Canada and around the world, sign up for breaking news alerts delivered directly to you when they happen. Sign up for breaking National newsletter Sign Up By providing your email address, you have read and agree to Global News' Terms and Conditions and Privacy Policy Breast cancer made up the largest share of the excess cancers, with about 4,800 additional cases. There were 2,000 more colorectal cancers compared with what would be expected based on the 2010 rates. There were 1,800 more kidney cancers and 1,200 additional uterine cancers. Reassuringly, death rates were not rising for most cancers in the young adult age groups, although increasing death rates were seen for colorectal, uterine and testicular cancers. Why is this happening? Explanations will take more research. The big databases used for the study don't include information on risk factors or access to care. Theories abound and a big meeting is planned later this year to bring together experts in the area. Story continues below advertisement 'Several of these cancer types are known to be associated with excess body weight and so one of the leading hypotheses is increasing rates of obesity,' said lead author Meredith Shiels of the National Cancer Institute. Advances in cancer detection and changes in screening guidelines could be behind some early diagnoses. 2:08 Self advocating a key step in accessing mammograms under 50, experts say For breast cancer, the trend toward women having a first child at older ages is a possible explanation. Pregnancy and breastfeeding are known to reduce risk. It's not a uniform trend for all cancers This isn't happening across the board. Cancer rates in people under 50 are going down for more than a dozen types of cancer, with the largest declines in lung and prostate cancers. Story continues below advertisement Cigarette smoking has been declining for decades, which likely accounts for the drop in lung cancer among younger adults. The drop in prostate cancer is likely tied to updated guidelines discouraging routine PSA testing in younger men because of concerns about overtreatment.
Euronews
09-05-2025
- Health
- Euronews
Which cancers are rising among people under age 50?
Cancer before the age of 50 is rare but increasing, and researchers want to know why. A new US government study provides the most complete picture yet of early-onset cancers, finding that the largest increases are in breast, colorectal, kidney, and uterine cancers. Scientists looked at data that included more than two million cancers diagnosed in people ages 15 to 49 between 2010 and 2019 in the US. Of 33 cancer types, 14 cancers had increasing rates in at least one younger age group. About 63 per cent of the early-onset cancers were among women, according to the study published on Thursday in the journal Cancer Discovery. "These kinds of patterns generally reflect something profound going on," said Tim Rebbeck of the US-based Dana-Farber Cancer Institute, who studies cancer risk and was not involved in the research. "We need to fund research that will help us understand". The researchers compared cancer rates in 2019 to what would be expected based on 2010 rates. Breast cancer made up the largest share of the excess cancers, with about 4,800 additional cases. Meanwhile, there were 2,000 more colorectal cancers, 1,800 more kidney cancers, and 1,200 additional uterine cancers than would be expected. Reassuringly, death rates were not rising for most cancers in the young adult age groups, although increasing death rates were seen for colorectal, uterine, and testicular cancers. Explanations will take more research. The big databases used for the study don't include information on risk factors or access to care. Theories abound, and a big meeting is planned later this year to bring together experts in the area. "Several of these cancer types are known to be associated with excess body weight, and so one of the leading hypotheses is increasing rates of obesity," said lead author Meredith Shiels of the US' National Cancer Institute. Advances in cancer detection and changes in screening guidelines could be behind some early diagnoses. For breast cancer, the trend toward women having a first child at older ages is a possible explanation. Pregnancy and breastfeeding are known to reduce risk. This isn't happening across the board. Cancer rates in people under 50 are going down for more than a dozen types of cancer, with the largest declines in lung and prostate cancers. Cigarette smoking has been declining in the US for decades, which likely accounts for the drop in lung cancer among younger adults. The drop in prostate cancer is likely tied to updated guidelines discouraging routine PSA testing in younger men because of concerns about overtreatment. A medication to treat men's hair loss comes with a rare risk of suicidal thoughts, the European Union's drugs regulator has determined. The safety committee of the European Medicines Agency (EMA) said it reviewed 313 reports of suicidal ideation among people taking the drug finasteride, which can stimulate hair growth and prevent hair loss for men aged 18 to 41. Finasteride is sold in 1 mg tablets under brand names such as Propecia. Meanwhile, 5 mg tablets are used to treat prostate enlargement that can cause problems urinating. Most of the reports of suicidal thoughts came from people taking the 1 mg tablets, but 'the frequency of the side effect is unknown,' the EMA concluded. Finasteride – which already comes with warnings about mood changes, such as depression and suicidal ideation – will remain on the shelves because the safety committee concluded that its benefits outweigh its risks. But the 1 mg tablets will now come with a card that reminds people of the risks and advises them on how to handle side effects, which can also include decreased sex drive or erectile dysfunction, the EMA said. The agency said people who experience mood changes while taking finasteride 1 mg should stop taking it and seek medical advice. The warnings will also be added to the medicine dutasteride, which is another treatment for prostate enlargement. The EMA safety committee did not have evidence linking the drug to suicidal thoughts, but because dutasteride works the same way as finasteride, the information will be added as a precaution. The agency noted that there were only a few hundred reports of suicidal ideation among about 270 million patients taking finasteride and 82 million taking dutasteride.
Time of India
09-05-2025
- Health
- Time of India
Cancer before age 50 is increasing. A new study looks at which types
New York: Cancer before age 50 is rare, but increasing, in the United States and researchers want to know why. A new government study provides the most complete picture yet of early-onset cancers , finding that the largest increases are in breast, colorectal, kidney and uterine cancers. Scientists from the National Cancer Institute looked at data that included more than 2 million cancers diagnosed in people 15 to 49 years old between 2010 and 2019. Of 33 cancer types, 14 cancers had increasing rates in at least one younger age group. About 63% of the early-onset cancers were among women. "These kinds of patterns generally reflect something profound going on," said Tim Rebbeck of Dana-Farber Cancer Institute, who studies cancer risk and was not involved in the research. "We need to fund research that will help us understand." The findings were published Thursday in Cancer Discovery, a journal of the American Association for Cancer Research . How many extra cancers are we talking about? The researchers compared cancer rates in 2019 to what would be expected based on 2010 rates. Breast cancer made up the largest share of the excess cancers, with about 4,800 additional cases. There were 2,000 more colorectal cancers compared with what would be expected based on the 2010 rates. There were 1,800 more kidney cancers and 1,200 additional uterine cancers. Reassuringly, death rates were not rising for most cancers in the young adult age groups, although increasing death rates were seen for colorectal, uterine and testicular cancers. Why is this happening? Explanations will take more research. The big databases used for the study don't include information on risk factors or access to care. Theories abound and a big meeting is planned later this year to bring together experts in the area. "Several of these cancer types are known to be associated with excess body weight and so one of the leading hypotheses is increasing rates of obesity," said lead author Meredith Shiels of the National Cancer Institute. Advances in cancer detection and changes in screening guidelines could be behind some early diagnoses. For breast cancer, the trend toward women having a first child at older ages is a possible explanation. Pregnancy and breastfeeding are known to reduce risk. It's not a uniform trend for all cancers This isn't happening across the board. Cancer rates in people under 50 are going down for more than a dozen types of cancer, with the largest declines in lung and prostate cancers. Cigarette smoking has been declining for decades, which likely accounts for the drop in lung cancer among younger adults. The drop in prostate cancer is likely tied to updated guidelines discouraging routine PSA testing in younger men because of concerns about overtreatment.
08-05-2025
- Health
Cancer before age 50 is increasing. A new study looks at which types
Cancer before age 50 is rare, but increasing, in the United States and researchers want to know why. A new government study provides the most complete picture yet of early-onset cancers, finding that the largest increases are in breast, colorectal, kidney and uterine cancers. Scientists from the National Cancer Institute looked at data that included more than 2 million cancers diagnosed in people 15 to 49 years old between 2010 and 2019. Of 33 cancer types, 14 cancers had increasing rates in at least one younger age group. About 63% of the early-onset cancers were among women. 'These kinds of patterns generally reflect something profound going on,' said Tim Rebbeck of Dana-Farber Cancer Institute, who studies cancer risk and was not involved in the research. 'We need to fund research that will help us understand." The findings were published Thursday in Cancer Discovery, a journal of the American Association for Cancer Research. The researchers compared cancer rates in 2019 to what would be expected based on 2010 rates. Breast cancer made up the largest share of the excess cancers, with about 4,800 additional cases. There were 2,000 more colorectal cancers compared with what would be expected based on the 2010 rates. There were 1,800 more kidney cancers and 1,200 additional uterine cancers. Reassuringly, death rates were not rising for most cancers in the young adult age groups, although increasing death rates were seen for colorectal, uterine and testicular cancers. Explanations will take more research. The big databases used for the study don't include information on risk factors or access to care. Theories abound and a big meeting is planned later this year to bring together experts in the area. 'Several of these cancer types are known to be associated with excess body weight and so one of the leading hypotheses is increasing rates of obesity,' said lead author Meredith Shiels of the National Cancer Institute. Advances in cancer detection and changes in screening guidelines could be behind some early diagnoses. For breast cancer, the trend toward women having a first child at older ages is a possible explanation. Pregnancy and breastfeeding are known to reduce risk. This isn't happening across the board. Cancer rates in people under 50 are going down for more than a dozen types of cancer, with the largest declines in lung and prostate cancers. Cigarette smoking has been declining for decades, which likely accounts for the drop in lung cancer among younger adults. The drop in prostate cancer is likely tied to updated guidelines discouraging routine PSA testing in younger men because of concerns about overtreatment. ___
Winnipeg Free Press
08-05-2025
- Health
- Winnipeg Free Press
Cancer before age 50 is increasing. A new study looks at which types
Cancer before age 50 is rare, but increasing, in the United States and researchers want to know why. A new government study provides the most complete picture yet of early-onset cancers, finding that the largest increases are in breast, colorectal, kidney and uterine cancers. Scientists from the National Cancer Institute looked at data that included more than 2 million cancers diagnosed in people 15 to 49 years old between 2010 and 2019. Of 33 cancer types, 14 cancers had increasing rates in at least one younger age group. About 63% of the early-onset cancers were among women. 'These kinds of patterns generally reflect something profound going on,' said Tim Rebbeck of Dana-Farber Cancer Institute, who studies cancer risk and was not involved in the research. 'We need to fund research that will help us understand.' The findings were published Thursday in Cancer Discovery, a journal of the American Association for Cancer Research. How many extra cancers are we talking about? The researchers compared cancer rates in 2019 to what would be expected based on 2010 rates. Breast cancer made up the largest share of the excess cancers, with about 4,800 additional cases. There were 2,000 more colorectal cancers compared with what would be expected based on the 2010 rates. There were 1,800 more kidney cancers and 1,200 additional uterine cancers. Reassuringly, death rates were not rising for most cancers in the young adult age groups, although increasing death rates were seen for colorectal, uterine and testicular cancers. Why is this happening? Explanations will take more research. The big databases used for the study don't include information on risk factors or access to care. Theories abound and a big meeting is planned later this year to bring together experts in the area. 'Several of these cancer types are known to be associated with excess body weight and so one of the leading hypotheses is increasing rates of obesity,' said lead author Meredith Shiels of the National Cancer Institute. Advances in cancer detection and changes in screening guidelines could be behind some early diagnoses. For breast cancer, the trend toward women having a first child at older ages is a possible explanation. Pregnancy and breastfeeding are known to reduce risk. It's not a uniform trend for all cancers Winnipeg Jets Game Days On Winnipeg Jets game days, hockey writers Mike McIntyre and Ken Wiebe send news, notes and quotes from the morning skate, as well as injury updates and lineup decisions. Arrives a few hours prior to puck drop. This isn't happening across the board. Cancer rates in people under 50 are going down for more than a dozen types of cancer, with the largest declines in lung and prostate cancers. Cigarette smoking has been declining for decades, which likely accounts for the drop in lung cancer among younger adults. The drop in prostate cancer is likely tied to updated guidelines discouraging routine PSA testing in younger men because of concerns about overtreatment. ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.
