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UPI
16-05-2025
- Business
- UPI
Novo Nordisk, U.S. biotech company team up to create obesity pills
Novo Nordisk will pay all the research and development costs for the project to develop new obesity pills. Photo by Towfiqu barbhuiya/ Pexels May 16 (UPI) -- Danish drugmaker Novo Nordisk is teaming up with California-based biotech Septerna to develop new pills to treat obesity, type 2 diabetes and other metabolic diseases. The deal could be worth up to $2.2 billion for Septerna. This includes more than $200 million in upfront and short-term milestone payments, plus future rewards tied to research, development and sales. Septerna will also get royalties on any future product sales, The Wall Street Journal reported. Novo Nordisk will pay all the research and development costs for the project. The U.S. biotech company has developed a platform that finds and develops drugs that target special proteins called G protein-coupled receptors. These proteins help pass chemicals from outside cells to the inside. Many major drugs on the market today also target GPCRs. Novo Nordisk's best-known drug, Wegovy, targets a GPCR called GLP-1. Eli Lilly's popular weight-loss drug Zepbound targets both GLP-1 and another GPCR called GIP. "Septerna has demonstrated strong capabilities in GPCR drug discovery," Marcus Schindler, chief scientific officer at Novo Nordisk, told The Wall Street Journal. "We are excited about the opportunity to develop oral small molecule medicines directed at multiple targets," he added. The two companies plan four programs to create pills that target GPCRs including GLP-1, GIP and glucagon -- which are important proteins involved in blood sugar and appetite control, The Journal said. Right now, leading weight-loss drugs must be injected into the body. Pill versions could make the drugs more convenient for patients and easier to ship and store. About one-third of drugs approved by the U.S. Food and Drug Administration target GPCRs, according to Novo Nordisk. But an estimated 75% of GPCR targets have not yet been used in medicine, meaning there's still a big opportunity for discovery. Septerna's stock jumped 69% in premarket trading after the deal was announced. Novo Nordisk's stock rose 1.2% in European trading. More information The Mayo Clinic has more on prescription weight-loss drugs. Copyright © 2025 HealthDay. All rights reserved.
Edinburgh Reporter
12-05-2025
- Business
- Edinburgh Reporter
What Does a Property Transfer Solicitor Do? A Beginner's Guide
A sale doesn't always transfer property ownership. It could change hands during a divorce, a family arrangement or after a death. In such cases, property transfer solicitors are very important to ensure that transfer of land or buildings from one party to another is done in a smooth, secure and in accordance with the current legislation. Photo by Towfiqu barbhuiya on Unsplash Understanding Ownership Transfers Property transfer is a process beyond a signature. This is a legal process of verifying ownership, drafting of formal documents, dealing with possible tax implications and registering changes with the relevant authorities. But when it is more than one party or more complex financial arrangements, each step must be perfect in alignment with the law. Reviewing Legal Title Before any changes are made official, a solicitor will scrutinise the property's title documents. This investigation uncovers such details as existing mortgages, legal charges, ownership restrictions or rights of way. Before moving ahead, any conflicting entries or missing information must be resolved. Drafting the Transfer Deed The solicitor prepares the legal form that officially alters ownership – usually a TR1 or TP1 document. These forms detail who is giving up the property and who is taking it on. They must be completed accurately, then signed and witnessed. Even a minor misstep in this documentation can create long-term legal issues. Managing Financial Interests If the property is still under mortgage, the transfer is usually subject to the approval of the lender. In these conversations, property transfer solicitors are facilitating consent, negotiating terms or helping to arrange for repayment if necessary. Lenders want to know that when ownership changes, their financial interest is not left unprotected. Ensuring Tax Compliance Not all transfers are exempt from tax. Depending on the value of the property and the nature of the transaction, Stamp Duty Land Tax may apply. For instance, adding a spouse to the deeds of a mortgaged property may still trigger a tax obligation. Solicitors identify these scenarios and often handle the filing of returns with HMRC. Coordinating with Third Parties Changes of ownership may need to involve other stakeholders, for example, managing agents for leasehold flats, housing associations in shared ownership schemes or trustees if the property is part of an estate. These communications are taken over by the solicitor who will ensure that necessary consents or notices are obtained. Registering the New Ownership Once the deed is signed and any tax paid, the final step involves applying to HM Land Registry to update the official record. This formal registration ensures that the new owner is legally recognised and protects against future disputes or fraud. When Do You Need a Property Transfer Solicitor? There's no one-size-fits-all answer. If you are transferring property between family members, removing someone from the deeds or formalising a gift, you may need legal support. There are other common scenarios, such as property adjustments in divorce, transfers after a death, or changes in connection with trusts and inheritance planning. Why Expertise Matters Property law is not forgiving of errors. A missed detail or incorrect filing could lead to delays, legal costs, or even invalid ownership. Choosing a solicitor with experience in title transfers ensures every step is carried out correctly, deadlines are met, and all legal responsibilities are fulfilled. Peace of Mind Through Professional Handling Shifting property from one name to another is simple enough, but there are legal aspects to ownership that must be taken into account. Property transfer solicitors serve as the compass through this terrain, helping their clients to protect their rights, remain compliant and avoid missteps. Their expertise ensures that your transfer is handled accurately and assuredly whether it is prompted by a life event or strategic planning. Like this: Like Related
