Latest news with #Veraxa
Yahoo
06-05-2025
- Business
- Yahoo
Veraxa and OmniAb to develop bispecific ADC tumour programme
Veraxa Biotech has entered a joint discovery partnership with OmniAb tp develop a bispecific antibody drug conjugate (bsADC) programme aimed at solid tumours. The partnership unites OmniAb's transgenic antibody discovery solutions with Veraxa's ADC linker technology and conjugation expertise to propel next-generation therapeutic discovery. Veraxa will commence a novel bsADC programme which addresses two target molecules in cancer medicine. The company will leverage OmniAb's transgenic antibody discovery solutions to procure high-quality human antibody leads, which will undergo natural optimisation via in vivo affinity maturation. Veraxa will then set up the bsADC lead candidate by applying its proprietary linker technology and conjugation approach and will oversee the preclinical validation process. The resulting bsADC programme will be co-owned by both companies, which will share future revenues from the programme's further development, licensing and commercialisation efforts. Veraxa co-founder and CEO Christoph Antz stated: 'This partnership brings together two highly complementary technologies to create a new class of bispecific ADCs. Bispecific ADCs represent a powerful opportunity to address difficult-to-treat solid tumours, and the collaboration fits squarely within our mission to drive innovation through targeted partnerships. 'Strategic collaborations will continue to be a mainstay in Veraxa's pipeline growth strategy, and today's announcement marks the second major initiative within the past six months, following our first radiopharmaceutical alliance late last year.' Veraxa focuses on the discovery and development of antibody-based therapeutics, such as bispecific T cell engagers, bispecific ADCs and other formats. The company is progressing its ADC pipeline and BiTAC (bi-targeted tumour-associated cytotoxicity) formats towards clinical development, leveraging transformative technologies and adhering to quality-by-design principles. In April, Veraxa Biotech announced is set to go public in the US through a merger with Voyager Acquisition Corp, a healthcare special purpose acquisition company. The deal is expected to close in the fourth quarter of 2025. "Veraxa and OmniAb to develop bispecific ADC tumour programme" was originally created and published by Pharmaceutical Technology, a GlobalData owned brand.
Yahoo
23-04-2025
- Business
- Yahoo
Veraxa to go public in $1.6bn SPAC deal with Voyager
Swiss oncology firm Veraxa Biotech is set to go public in the US through a merger with Voyager Acquisition Corp, a healthcare special purpose acquisition company (SPAC). The deal, expected to close in Q4 2025, will list Veraxa on the Nasdaq stock exchange, trading under the ticker symbol VERX. The deal also gives Veraxa access to US capital markets as it continues to expand its pipeline of targeted cancer therapies. The merger values the combined entity at approximately $1.64bn on a pro forma equity basis, assuming no shareholder redemptions. Under the terms of the agreement, Veraxa's shareholders will receive around 130 million shares in the newly formed company, priced at $10 per share. Veraxa's equity contribution to the deal is valued at nearly $1.3bn. Upon completion of the transaction, Veraxa will gain access to approximately $253m in cash currently held in Voyager's trust account. The company also plans to pursue an additional financing round to further bolster its cash reserves and support ongoing R&D efforts. Founded and incubated by Swiss investment firm Xlife Sciences, Veraxa is developing a range of antibody-based cancer therapies, including antibody-drug conjugates (ADCs) and bispecific T-cell engagers. Its lead clinical asset VX-A901 is an anti-FLT antibody in early-stage trials for haematologic malignancies. The candidate was added to Veraxa's pipeline following the company's 2024 acquisition of Synimmune. Veraxa's core innovation lies in its bi-targeted tumour-associated cytotoxicity (BiTAC) platform. The technology is designed to enhance the safety and specificity of antibody-based cancer treatments. It uses a dual-antibody approach that only forms an active therapeutic molecule when both antibody precursors bind simultaneously to distinct tumour-associated targets. This proximity-dependent activated mechanism is intended to reduce off-target toxicity – a common limitation of current immune-oncology therapies. The company currently has three BiTAC programmes in preclinical development. Two of these target lung and pancreatic cancers, while the third is aimed at ovarian and breast cancers. Veraxa said that it will be pursuing multiple strategic partnerships and licensing opportunities in 2025 and 2026. Veraxa's CEO Christoph Antz said the company's platform is designed to address the limitations of existing therapies in the 23 April announcement: 'Side effects too often limit today's cancer therapies and prevent doctors from applying optimal dose levels. Our latest platform innovation, the BiTAC format, is designed to specifically address this issue and create first-in-class drug candidates with unprecedented safety and efficacy.' Voyager's chairman Warren Hosseinion noted growing interest in ADC and bispecific antibody therapies as part of the rationale for the merger. 'We believe next-generation ADCs and bispecifics will continue to revolutionise oncology, due to their significant improvement over standard of care treatments and higher probability of technical and regulatory success compared to other oncology drugs, as evidenced by multiple deals in excess of $1bn each since 2023 in this space.' According to GlobalData figures, the antibody drug conjugate market was valued at $8.6bn in 2023, with expectations to exceed $45bn by 2030. GlobalData is the parent company of Pharmaceutical Technology. Recent transactions in the space support the positive outlook. In October 2023, MSD entered a co-development deal with Daiichi Sankyo worth up to $22bn for three ADC assets. Around the same time, GSK secured exclusive rights to Duality Biologics' gastrointestinal ADC candidate DB-1324 in a deal worth over $1bn. In March 2025, Sanofi announced it would acquire Dren Bio's bispecific antibody DR-0201 for up to $1.9bn. Other major ADC transactions include a $1bn licencing agreement between Danish biotech Adcendo and China-based Multitude for ADCE-T02, a tissue factor-targeting ADC. "Veraxa to go public in $1.6bn SPAC deal with Voyager" was originally created and published by Pharmaceutical Technology, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Sign in to access your portfolio
