Latest news with #adults
Condé Nast Traveler
3 hours ago
- Lifestyle
- Condé Nast Traveler
Airfield Estate — Landmark Review
When in Ireland, immersing yourself in the greenery of the Emerald Isle is a must, as often as possible. This 38-acre farm and garden oasis is perfect for families in need of fresh air and a bit of space to run around and engage in a daily schedule of activities like meeting donkeys, witnessing a cow milking, thematic storytime, nature-inspired crafts, and more for all ages. Adults can also enjoy date night cooking classes, houseplant and flower arranging workshops, and more.
Al Jazeera
6 hours ago
- General
- Al Jazeera
Video: What we know about plane crash at Bangladesh school
What we know about plane crash at Bangladesh school NewsFeed Bangladesh has declared a national day of mourning for dozens of children and adults who were killed when a military plane crashed into a school. Here's what we know about the crash. Video Duration 01 minutes 24 seconds 01:24 Video Duration 00 minutes 38 seconds 00:38 Video Duration 00 minutes 44 seconds 00:44 Video Duration 00 minutes 37 seconds 00:37 Video Duration 01 minutes 46 seconds 01:46 Video Duration 01 minutes 24 seconds 01:24 Video Duration 00 minutes 58 seconds 00:58
Medscape
13 hours ago
- Health
- Medscape
Cardiac Arrest Survival Rises Over Last Two Decades
TOPLINE: While the incidence of cardiac arrest occurring outside the hospital has remained relatively stable, at about 81 per 100,000 person-years, between 2001 and 2020, data show survival rates improved from 14.7% to 18.9% during that period. This improvement corresponded with increased bystander cardiopulmonary resuscitation (CPR), from 55.5% to 73.9%, and the use of early automated external defibrillators, from 2.2% to 10.9%. METHODOLOGY: Researchers conducted a retrospective cohort analysis of 25,118 adults in King County, Washington, who had experienced an out-of-hospital cardiac arrest (OHCA) treated by emergency medical services (EMS) between 2001 and 2020. Of those, 15,994 (63.7%) were men and 9124 were women; the median age was 65 years. Annual incidence calculations were stratified by sex, age group (less than 65 years and 65 years or older), and initial rhythm (shockable, nonshockable). The tesearchers evaluated temporal trends using Poisson regression for incidence and survival to hospital discharge, with resuscitation assessed in five-year groups. TAKEAWAY: Overall survival to hospital discharge improved significantly over time: 14.7% (859 of 5847 individuals) in 2001-2005, 17.4% (1024 of 5885 individuals) in 2006-2010, 19.3% (1232 of 6376 individuals) in 2011-2015, and 18.9% (1322 of 7010 individuals) in 2016-2020 (P < .001 for trend). Survival rates increased substantially for shockable OHCA, from 35% to 47.5%, and for nonshockable OHCA, from 6.4% to 10.1% between the periods spanning 2001-2005 and 2016-2020 (P < .001 for trend). Improvements were observed in both prehospital resuscitation (survival to hospital admission) and in-hospital survival (P < .001 for trend). Community response rose significantly, with bystander CPR increasing from 55.5% to 73.9% and early use of an automated external defibrillator rising from 2.2% to 10.9% (P < .001 for trend). IN PRACTICE: 'Resuscitation outcomes improved over time, a temporal trend that was evident overall and when stratified by presenting arrest rhythm,' the researchers reported. 'The outcome improvements corresponded to improvements in health services such as increase in bystander CPR, AED application before EMS among patients with shockable rhythm, and hospital-based care with targeted temperature management and coronary intervention. The results demonstrate the dynamic nature of OHCA incidence and resuscitation care and outcome that collectively help provide a foundational context to consider strategies of prevention and treatment.' SOURCE: The study was led by Owen McBride, MD, of the Department of Emergency Medicine at the University of Washington in Seattle. It was published online July 16 in JAMA Cardiology. LIMITATIONS: According to the authors, while the study represents a singular regional experience that could affect generalizability, as OHCA incidence and outcome can vary based on geography. Some people who experience OHCA have an emergency response but do not receive resuscitation attempts due to signs of irreversible death or do-not-resuscitate orders, whereas some OHCA events do not receive a 911 medical response. DISCLOSURES: Michael Sayre, MD, reported receiving personal fees from Styker Emergency Response outside the submitted work. Thomas Rea, MD, MPH, reported receiving grants from Philips Medical Funding and the American Heart Association for research independent of the current publication. Additional disclosures are noted in the original article. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Washington Post
2 days ago
- Health
- Washington Post
I recently broke up with my longtime partner. How do I sleep better alone?
I recently broke up with my longtime partner and am having trouble falling and staying asleep. What can I do to improve my sleep? You are not alone in struggling with this problem. Trouble with sleep after a relationship change is common. Our brain makes associations between our environment and our behaviors. Just like a quiet room can promote peaceful sleep, or listening to a certain audiobook may help with relaxation at bedtime, the presence of a bed partner can also become associated with restful sleep. Following a breakup, the absence of that person can result in disrupted sleep. Acute insomnia occurs in about one-third of adults every year, and most people experience acute insomnia following a breakup. For many people, this can be temporary, but if the change prompts negative sleep associations or habits, then the sleep loss can persist long after people move on from other aspects of the breakup. Breakups can affect sleep on two levels. First, healthy sleep depends on a reliable routine, which includes sleep habits (activities before getting into bed and before going to sleep) and the sleep environment. A breakup typically interrupts these routines: The former partner is no longer present in the bed or part of the bedtime routine. Second, breakups are often emotional and stressful, and acute insomnia is a common — even normal — response to stress. Thinking about the factors involved in the relationship change, and the emotions associated with it, keep the brain busy, and busy brains have a hard time falling asleep. Also, feelings of loneliness or loss, which may be kept at bay during the day, can emerge at night. Getting into an empty bed at night is itself a physical reminder of the change and its accompanying emotions — which alone would be enough to disrupt sleep. But there is an additional, more basic, reason that contributes to post-breakup insomnia: The sleep environment has changed from co-sleeping to sleeping alone. By habitual co-sleeping, the brain learned to associate the presence of another person with falling asleep; after a breakup, the brain must relearn how to fall asleep without another person nearby. Reclaiming your rest following a breakup may require adaptations to your sleep environment, routines and perspective. To disconnect your sleep space from a former partner and make it yours again, try an intentional physical change. Move from the side to the middle of the bed, use a body pillow or a blanket with a new texture, or change the arrangement of the bedroom. These tweaks can help create new sleep associations to minimize the impact of the loss of a habitual bed partner. Some people find it helpful to spend time in a guest room or a different sleep area through the transition because that space is not immediately associated with a former partner. Missing a component of the typical sleep routine — a former bed partner, for instance — changes how people wind down and settle into sleep. This often results in trouble falling asleep or feeling that sleep is less restful throughout the night. A breakup may be a good time to create new routines that help to make sleep a positive and restful experience. Try calming or mindfulness practices, gentle stretching exercises or a cup of warm tea. A new habit around bedtime can then feel like a 'new' or 'positive' change that optimizes your comfort, rather than just trying to make up for the loss of a partner. At night, ruminations can loom larger than during the day — when there are distractions and routines that move us forward. Also, loneliness can feel deeper, stress more consuming and frustrations more acute. Finding an active distraction strategy can be helpful. For instance, a calming podcast or audiobook can refocus your thoughts away from the breakup. The key to an effective distraction strategy is identifying something interesting enough to hold your attention, but not so fascinating that you can't fall asleep while reading, listening or thinking about this topic. Ideally, this is something not associated with a prior bed partner. These techniques also prevent your current disturbed sleep from becoming a long-term problem. For example, if emotions such as frustration and anxiety become a habit once your head hits the pillow, then your brain learns to associate bedtime with these stressful thoughts. To set yourself up for success, don't get into bed until you are really sleepy. This is good advice in general, but can be especially helpful when there is something unsettling about the sleep space (such as a reminder that someone isn't there). Reminding yourself that difficulty with sleeping through a breakup is normal can minimize the anxiety associated with poor sleep. If you find yourself focusing on the sleep loss, staring at the ceiling in anger or desperately counting the diminishing hours of potential rest, tell yourself that rocky nights are allowed while you adjust to new circumstances and that sleep will fall back into place. Try to avoid spending the time you can't sleep ruminating on stressful topics, and allow yourself time to rest, even if you are not sleeping perfectly. As your sleep routines adjust to the new circumstance, you will start getting more restful sleep. And know when to ask for help: If post-breakup sleep difficulties become a pattern, sleep is troublesome more nights than not, or if the sleep disruption impacts your daytime function, it might be time to talk with a clinician to get the support you need to get back to a good night of sleep. Margaret Blattner, MD, PhD, is a neurologist and sleep medicine physician in the Department of Neurology at Beth Israel Deaconess Medical Center and clinical instructor in neurology at Harvard Medical School. If you have a question for a therapist about mental health, relationships, sleep, dating or any other topic, email it to AskATherapist@ and we may feature it in a future column.
Medscape
4 days ago
- Health
- Medscape
Brain Activity May Predict TNF Inhibitor Response in RA
TOPLINE: Adults with rheumatoid arthritis (RA) and high levels of pain activation in their brain responded better to the TNF inhibitor certolizumab pegol in a phase 3 trial. METHODOLOGY: Randomized phase 3 trial at six centers in Germany, Serbia, and Portugal (September 2013 to January 2020) assessed response to a TNF inhibitor in RA based on disease-related central nervous system (CNS) activity. Trial included 139 adults with RA (mean age, 54.3 years; 71% women) who had a disease activity score in 28 joints (DAS28) > 3.2 and an inadequate response to at least one synthetic disease-modifying antirheumatic drug. Patients were stratified by high or low CNS-activated brain volume due to pain and randomly assigned to placebo or 400 mg certolizumab pegol at weeks 0, 2, and 4, then 200 mg every 2 weeks for up to 24 weeks. A placebo group (n = 47) and two certolizumab pegol groups were formed: one with high CNS-activated volume (n = 49) and one with low CNS-activated volume (n = 43). The primary outcome was achieving DAS28 ≤ 3.2 at 12 weeks; a predefined difference in DAS28 of > 0.6 points was required between patients with high CNS-activated volume on certolizumab and patients on placebo. TAKEAWAY: Low disease activity was achieved by 57% and 44% of patients in the certolizumab pegol groups with high and low CNS-activated volumes, respectively, and by 26% of patients in the placebo group. The high CNS-activated volume group showed a better response than the placebo group (P =.0017) and met the predefined difference in DAS28, but the low CNS-activated volume group did not. The mean DAS28 values at week 12 among patients on certolizumab were 3.1 and 3.4 in those with high and low CNS-activated volumes, respectively, and 3.8 for those on placebo. A total of 25 treatment-related adverse events were reported, with 22 in patients who received certolizumab pegol and three in those who received placebo. IN PRACTICE: 'These data highlight the role of subjective patient-related parameters in the response to cytokine inhibition and suggest that a high-volume representation of the disease in the CNS — involving more frontal-associative brain circuits — increases the likelihood to respond to TNF inhibitor, ' the study authors concluded. 'In terms of prediction, this study certainly supports a role for brain-derived data, but, at this stage, it appears the contribution is complementary rather than comprehensive; thus, their integration into multiparametric biomarkers should be considered,' experts wrote in an accompanying comment. SOURCE: This study was led by Andreas Hess, PhD, Institute of Pharmacology and Toxicology, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany. It was published online on June 23, 2025, in The Lancet Rheumatology. LIMITATIONS: DAS28-CRP was used for low disease activity assessment; however, the threshold was validated for DAS28-ESR. Functional MRI measurements may be influenced by the mental or circulatory health of the patient or technicalities of image acquisition. DISCLOSURES: This study received support from UCB Biopharma. Additional support was received from the Bundesministerium für Bildung und Forschung. Three authors reported receiving support from the Deutsche Forschungsgemeinschaft. Several authors reported receiving research grants, honoraria, or consulting fees, and having other financial ties with several pharmaceutical companies, including UCB, AbbVie, and Lilly. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
