19-05-2025
Humanized Mouse and Rat Model Market Report 2025 - Market to Hit USD 409.8 Million by 2030
Humanized mouse models dominate the market type segment, expected to maintain the fastest growth through 2030 due to their utility in drug discovery and immuno-oncology research. North America leads the market, primarily driven by U.S. advancements. Key players include Charles River Laboratories and The Jackson Laboratory. Growing demand for specialized testing and the rise of CROs & CDMOs present further opportunities.
Dublin, May 19, 2025 (GLOBE NEWSWIRE) -- The "Humanized Mouse and Rat Model Market by Type, Application, End User, and Region - Global Forecast to 2030" report has been added to report segments the market by type, application, end user, and region, covering core factors like drivers, challenges, and opportunities influencing growth. It provides a detailed analysis of leading players, examining their products, strategies, and recent developments.
The global humanized mouse and rat model market is projected to grow from USD 276.2 million in 2025 to USD 409.8 million in 2030, reflecting a robust CAGR of 8.2%. This growth is driven by increased R&D investments in pharmaceutical and biopharmaceutical sectors. The expansion of R&D pipelines is increasing the demand for outsourcing analytical testing, heightened by concentrated research initiatives on rare diseases and orphan drugs.
The expensive nature of in-house drug development further fuels this trend, along with technological advancements, novel drug discovery techniques, and a rising demand for specialized testing services.
Humanized Mouse Model Segment Leads
The market is divided into humanized mouse models and humanized rat models. In 2024, humanized mouse models dominated the revenue share and saw the fastest CAGR growth. The surge in demand for cell-based humanized mouse models is powering this segment's expansion, supporting applications in drug safety and efficacy analysis, long-term studies in immuno-oncology, infectious diseases, and graft-versus-host disease.
Immunology & Infectious Diseases: A Key Segment
The humanized mouse and rat model market is segmented by application into several areas, including oncology and neuroscience. The immunology & infectious diseases segment held the second-largest market share in 2024. Mouse models are pivotal in immunology and inflammation studies, facilitating detailed analyses of immunological processes through targeted alterations in the mouse genome.
Pharmaceutical & Biotechnology Sector to Record Highest Growth
Among end users, pharmaceutical & biotechnology companies, CROs & CDMOs, and academic & research institutes are significant segments. Pharmaceutical & biotechnology companies dominated in 2024 due to increasing expenditure on innovative drug development and the shift towards personalized medicine. However, the CROs & CDMOs segment is predicted to have the highest growth, driven by rising outsourcing of preclinical studies and drug development activities.
US Market Growth Leading the Way
The market is categorized by geography into regions such as North America, Europe, and Asia Pacific. North America led in 2024, with the United States at the forefront, backed by substantial life sciences research funding and active research in mAbs and biosimilars. This dominance is also supported by a rising incidence of cancer.
Competitive Landscape
Key industry players include Charles River Laboratories, The Jackson Laboratory, Taconic Biosciences, JSR Corporation, Champions Oncology, and CLEA Japan Inc. Others are genOway, Inotiv, Janvier Labs, Altogen Labs, Vitalstar Biotechnology, Ingenious Targeting Laboratory, Reaction Biology, Harbour BioMed, Oncodesign Services, Pharmatest Services, Ozgene Pty Ltd., TransCure bioServices, Cyagen Biosciences, Aragen Life Sciences, GemPharmatech, and Biocytogen.
Benefits of the Report: The report offers market leaders and new entrants close approximations of revenue numbers and valuable insights to enhance market positioning. It enables stakeholders to grasp market dynamics and devise effective strategies.
Report Insights Include:
Analysis of market drivers, like the increased use of humanized models in drug discovery.
Detailed insights into product development and upcoming technologies.
Comprehensive information on growth across varied regions.
Exhaustive data on new products, untapped geographies, and market investments.
In-depth competitive assessment of market leaders.
Key Attributes:
Report Attribute
Details
No. of Pages
255
Forecast Period
2025 - 2030
Estimated Market Value in 2025
276.2 million
Forecasted Market Value by 2030
409.8 million
Compound Annual Growth Rate
8.2%
Regions Covered
Global
Key Topics Covered: Market Dynamics
Drivers
Rising Use of Humanized Models in Drug Discovery Research
Emerging Preclinical Applications of Humanized Mouse Models
Government-Funded Initiatives For Cancer Research
Increasing R&D Activities in Pharmaceutical & Biotechnology Industry
Restraints
Introduction of FDA Modernization Act 2.0/3.0
Stringent Regulatory Compliance For Ethical Use of Animal Models
Opportunities
Growing Preference For Humanized PDX Models
Emergence of Crispr in Biomedical Research
Challenges
Alternative Methods For Animal Testing
Limitations of Humanized Mouse Models
Company Profiles
Charles River Laboratories
The Jackson Laboratory
Inotiv
Genoway
Taconic Biosciences, Inc.
Jsr Corporation
Champions Oncology, Inc.
Janvier Labs
Vitalstar Biotechnology
Ingenious Targeting Laboratory
Harbour Biomed
Oncodesign Services
Pharmatest Services
Ozgene Pty Ltd.
Clea Japan, Inc.
Altogen Labs
Reaction Biology
Transcure Bioservices
Cyagen
Aragen Life Sciences Ltd.
Biocytogen
Gempharmatech
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