Latest news with #kidneystones
Medscape
6 days ago
- General
- Medscape
Supplements Show Potential for Kidney Stone Prevention
ORLANDO, Fla. — Certain dietary supplements inhibit the formation, growth, and aggregation of calcium oxalate kidney stones and may ultimately aid in prevention, according to new research presented this week at NUTRITION 2025, the annual meeting of the American Society for Nutrition. 'We have searched for many new approaches with a hope of reducing kidney stone disease and its recurrence,' Visith Thongboonkerd, MD, Siriraj Hospital, Mahidol University in Bangkok, Thailand, told Medscape Medical News . Recent work by Thongboonkerd and colleagues found that while normal urinary proteins (proteome) inhibit calcium oxalate crystallization, growth, and aggregation, the urinary proteome of individuals who form kidney stones actually promotes these calcium oxalate crystal parameters via oxidative modifications. The new findings, presented at NUTRITION 2025, represent the team's efforts to investigate whether dietary supplements could modulate these oxidative modifications, potentially preventing stones from forming. Inhibitory Effects Revealed Using crystallization, growth, and aggregation assays, the team compared the modulatory effects of caffeine, epigallocatechin-3-gallate (EGCG), N-acetylcysteine (NAC), resveratrol, and trigonelline (at 1, 10, and 100 μM — ie, within their physiologic range in urine) on calcium oxalate crystals. They found that the supplements had diverse effects: Caffeine inhibited crystal formation, EGCG inhibited crystal formation and growth, NAC inhibited crystal aggregation, resveratrol inhibited crystal growth, and trigonelline inhibited crystal growth and aggregation. Notably, however, resveratrol also promoted crystal aggregation and thus served as a dual modulator, acting as an inhibitor and promoter at different steps of stone formation. Further analyses revealed that EGCG was the most potent inhibitor against calcium oxalate crystal formation, whereas resveratrol was the most potent inhibitor against calcium oxalate crystal growth. NAC was the only inhibitor against calcium oxalate crystal aggregation. The findings support roles of these supplements in kidney stone disease prevention, the authors suggested. 'It will take a while before we can draw a clear conclusion that prescribing these supplements would really be beneficial to kidney stone patients, without any harms,' Thongboonkerd acknowledged. Next steps would include validating the in vitro findings in clinical settings. Thongboonkerd disclosed having no conflicts of interest.
Daily Mail
23-05-2025
- Health
- Daily Mail
Man who drank up to three litres of Coca Cola every day has to have 35 stones removed from his bladder
A doctor has warned of the dangers of drinking too many fizzy drinks, after he was forced to remove 35 stones from the bladder of a man who had a habit of drinking three litres of Coca-Cola every day. In an Instagram video that's so far attracted more than 8.5 million views, Brazil-based urologist Dr Thales Andrade said 'excessive' consumption of sugary, fizzy drinks can cause kidney stones. Speaking in portuguese, he showed viewers a dish of several large yellow stones that he had removed, as the patient lay on the table following the procedure. Kidney stones are calcium deposits that build in the urinary tract and move to the bladder to be urinated out, causing sharp pain, nausea, vomiting, pinching or stinging and potentially blood in the urine. If left untreated, they can migrate to the bladder and lead to life threatening complications like kidney failure or sepsis—when the body attacks its own tissues and organs. The caption below the video explained how the stones developed. Drinking too much Coca-Cola, which contains high amounts of sugar, can increase the amount of calcium in the body, raising the risk of stones forming. What's more, carbonated beverages are filled with chemicals like phosphoric acid, which creates an acidic environment in the kidneys that is further encouraging of the formation of hard stone-like lumps. Dr Andrade added: 'Maintaining adequate hydration and avoiding excessive consumption of soda are essential measures for prevention. Kidney health begins with the daily choices of what we drink.' According to the National Kidney Foundation, the larger the stone, the more noticeable the symptoms. A severe pain on either side of the lower back is a common complaint. These periods of intense pain may last for minutes or hours. Blood in the urine, a urinary tract infection and feeling sick or vomiting are also other common warning signs of the ailment. Kidney stones affect more than one in ten people, mostly aged between 30 and 60, and are caused by waste products in the blood forming crystals. Over time, crystals build up to form a hard stone-like lump. Once a kidney stone has formed, the body will tries to pass it through urine. Most are small enough to do so and can be managed at home. When they get too big, however, surgery is usually needed to remove them.
News.com.au
23-05-2025
- Sport
- News.com.au
Brazilian jockey Manoel Nunes returns to riding after suffering from kidney stones that left him ‘crying in pain'
Manoel Nunes is back in the saddle at Murray Bridge on Saturday, after a bout of kidney stones kept the Group 1-winning hoop sidelined during the Adelaide racing carnival. Nunes competed on Sangster Stakes day on April 26, but found himself in a Singapore hospital earlier this month during a quick trip back to the region to visit his girlfriend. • Nunes, 48, woke up in agony during the early hours of the morning, before being rushed to the emergency room. 'I was in the hotel at 4am, sleeping, and suddenly I woke up in a lot of pain,' Nunes said. 'The pain was really bad, I couldn't breathe, I rang my girlfriend, luckily she answered the phone. 'I was crying in pain, it was very, very painful, 'she said what's happened?', I said 'please come here, and bring me to the hospital'. 'I couldn't explain to her, I got off the phone and about half an hour later she got to the hotel and took me to the emergency in Singapore. 'I discovered I had kidney stones, straightaway they put me on a drip, they did a CT scan, and one of them had dropped, that's the one that was causing the pain. 'They removed a lot of stones from the kidneys, it was very painful.' Manoel Nunes finishes the day with a treble at Morphettville ðŸ'Š — (@Racing) November 9, 2024 • Crowther targets return to saddle from nasty injury With the SA Derby (May 3) only days away, the episode saw Nunes miss the meeting and Goodwood day the following week, in a stroke of ill-luck for the Brazilian hoop. He was in hospital for a day and a half, and returned to Adelaide last week. 'I couldn't ride for about two weeks,' he said. 'I went there to do a few things and come back for the Derby meeting, I had no intention to miss it but then that happened.' Nunes has been a welcome addition to Adelaide's riding ranks, the multiple premiership winner in Singapore and Macau has notched 25 city winners after making a move to South Australia in October following the closure of racing in Singapore. Nunes is booked for five rides on Saturday's nine-race card at Murray Bridge. 'I love what I'm doing, I love my job, you feel a little bit upset when you watch the races and cannot ride. I'm very happy to come back on Saturday,' he said. 'Adelaide is a very quiet place, I'm in Glenelg, it's a beautiful spot. I'm very happy to be here.' Nunes made the move to Adelaide on his own, his partner still lives and works in Singapore and visits him as often as she can. Singapore-owned horses Bakeel, Makin, Ghalib and Asif, owned by Mansoor Gandhi, are being transferred from Adelaide to Perth after stints with Angaston trainers Aaron Bain and Ned Taylor. Nunes has a strong affiliation with the quality gallopers, but never entertained a move to Western Australia himself. 'Obviously when the horses run, maybe I get on the plane and ride the horses for him (Mansoor),' Nunes said. 'But no, it never come to my mind to go and move there, you never say no, but so far now it hasn't passed my mind to move to Perth.' 'I appreciate the support from the trainers and owners who support me. 'And of course Damien (Wilton) my manager, who has hooked me up with stables from Melbourne and Sydney. 'When they come over they put me on – I'm very happy with that.'
Daily Mail
21-05-2025
- Health
- Daily Mail
Safety alert over popular ice baths after man develops agonising condition - 'it's the most dangerous health trend out there'
A health coach has sounded the alarm over the popular ice-bath trend that sees people plunging into freezing temperatures—after he was left with a debilitating condition that can trigger organ failure. The performance coach, who goes by joeinbalance on Instagram, told his followers that despite its mood-boosting abilities, the practise is 'the most dangerous health trend out there.' In a video that has been viewed over 4.4million times so far, Joe alleged that doing the plunges regularly for a year had resulted in him developing kidney stones. These caused by waste products in the blood forming crystals that over time, form a hard, stone-like lump in the kidneys. Once a kidney stone has formed, the body will tries to pass it through urine which, if depending on the size, can be extremely painful. If untreated, the stones can trigger potentially serious urine infections and blockages, which raises the risk of kidney failure. Fitness fanatic Joe, who developed kidney stones at just 18-years-old, described the condition as 'the worst pain I've ever experienced'. Initially, Joe—who has also trained in nutrition—thought that the stones were unrelated to his ice bath routine. At first I loved the adrenaline rush and the dopamine high', he said. But, when he suffered two more kidney stones in quick succession, his 'mind finally clicked'. 'I started connecting the dots,' he explained, adding that he believes the freezing temperatures puts undue stress on the immune system, causing waste products to build up in the blood. Cold exposure also increases urination and dehydration which promotes the formation of kidney stones, he added. Not drinking enough water is a well-known cause of kidney stones. Diet, lifestyle, and genetics also play a role in the likelihood of someone developing kidney stones. But, Joe said: 'Ice bathing definitely made [my kidney stones] worse.' He also noted that he has had no new stones appear since he stopped ice baths three years a go. He is now urging people to take an alternative approach to holistic health, swapping freezing cold plunges for sauna sessions instead. Sauna-lovers say the hot rooms have a variety of health benefits including managing stress and easing muscle pain. Ice baths have also surged in popularity in recent years, amid claims they can boost circulation and improve heart health. Plunging into cold water trigger's the body's cold shock response, where a sudden drop in temperature leads to a surge in adrenaline, noradrenaline and other hormones that boost feelings of alertness. This process is believed to be behind the alleged health benefits, although experts have warned that not everyone will reap the same rewards. Experts warn that ice baths come with an increased risk of hyperventilation and hypothermia. This is because, when the body is suddenly exposed to cold water, we almost instantly take a deep breath as the body demands oxygen. This is followed by hyperventilation—a rate of rapid breathing ten times faster than normal. Sudden exposure to cold water also dramatically increases the risk of cardiac arrest as the body desperately attempts to slow the amount of heat escaping to keep the vital organs functioning as normal. At the same time, heart rate increases, putting the organ under immense strain, creating a potentially fatal spike in blood pressure. As of last year's figures, 11 people are thought to have died as a result of cold water exposure. However, researchers in Canada recently found that cold plunges can help ward off disease and slow down biological aging. The researchers tracked 10 healthy men who took the plunge for 60 minutes a day over the course of a week. Overtime, analysis of blood biomarkers showed there was a reduction in inflammation and cellular damage. Dr Kelli King, who lead the study, said: 'Cold exposure might help prevent diseases and potentially even slow down aging at a cellular level. It's like a tune-up for your body's microscopic machinery.' He suggested that the stress response from the cold water was responsible for the boost in cell function.
Daily Mail
06-05-2025
- Entertainment
- Daily Mail
Barstool star Dan Katz left hospitalized with brutally painful health issue
Popular Barstool personality Big Cat had to be hospitalized over the weekend with a major health issue. Barstool Big Cat, whose real name is Dan Katz, took to social media on Sunday to reveal that he had ended up in the emergency room with kidney stones. Katz has since been released, according to ESPN's NFL insider Adam Schefter, who announced the news in an NFL Draft parody post on X Tuesday morning. 'Developing story: Over the weekend, @BarstoolBigCat was hospitalized due to a kidney stone. He since has been released, and with that episode seemingly over, @PFTCommenter is now on the clock,' Schefter wrote. This wasn't the first time that the 40-year-old has been struck down with kidney stones. Last November, he revealed that he had suffered with four. 'I try to p*** one out,' he said of the situation last year on the Barstool Yak podcast. 'Three are small inside my kidney still, that maybe won't f*** me up. One is already on its way out and that's the big boy.' 'I think it's kinda random, it might be stress cause I am really stressed,' he added when asked about the cause. However, he claimed at the time that his trip to hospital hadn't been the worst part of the weekend as his beloved Chicago Bears had lost. His latest incident didn't keep him down for long though, as Katz was released from hospital in time to attend Barstool's 'Bet Gala.' Barstool chief Dave Portnoy hosted a parody of the Met Gala - a fashion spectacular at the Metropolitan Museum of Art in New York - on Monday night in Scottsdale, Arizona. Katz shared a series of photos of himself in a gambling-inspired suit, which was lined with winning bet slips.
