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Leukemia and lupus: Link and research explained
Leukemia and lupus: Link and research explained

Medical News Today

time7 days ago

  • General
  • Medical News Today

Leukemia and lupus: Link and research explained

Link explained Cancer risk Symptoms Seeking medical help Summary Leukemia and lupus are both conditions that affect the immune system. Although they are different, they share certain symptoms. A person with lupus may have increased risk of developing leukemia. Lupus is an autoimmune disease. A person's immune system is responsible for protecting the body from infection and disease. Autoimmune conditions affect the immune system, causing it to attack healthy tissue. Leukemia is cancer of the blood. There are different forms of leukemia. The type a person has is determined by what type of blood cell it affects, as well as its speed of growth. Some forms of leukemia affect the white blood cells. White blood cells help to fight diseases as part of the immune system. If a person has a problem with their white blood cells, they may be prone to sickness or infection. Lupus and leukemia have certain symptoms in common. Additionally, some research suggests that there may be a link between the two conditions. Read on to learn more about the relationship between lupus and leukemia, as well as when to see a doctor. AbrahamCertain research suggests that there may be a link between lupus and leukemia. A review from 2018 found that having lupus may increase a person's overall risk of developing cancer. It may also increase a person's risk of specific cancers, including: leukemia non-Hodgkin's lymphoma Hodgkin's lymphoma multiple myeloma cervical cancer vaginal/vulval cancer renal cancer bladder cancer esophageal cancer gastric cancer hepatobiliary cancer lung cancer oropharynx cancer larynx cancer non-melanoma skin cancer thyroid cancer Additionally, research from 2022 noted that autoimmune hemolytic anemia (AIHA) may increase a person's risk of leukemia. AIHA is a condition that causes the immune system to destroy red blood cells. A further study from 2022 stated that around 10% of people with lupus develop AIHA. A study from 2024 noted that there are rare reports of chronic myeloid leukemia (CML) occurring alongside lupus. CML is a form of leukemia that affects the blood and bone marrow. Researchers believe that lupus may increase a person's risk of certain cancers due to its weakening of the immune system. Further research is required to determine the link between lupus and leukemia. A doctor may use immunosuppressants to treat a person with lupus. Immunosuppressants work by suppressing a person's immune system. This helps to prevent it from damaging healthy tissue. However, immunosuppressants may reduce how well the immune system works. This may weaken a person's immune system, causing them to become vulnerable to infections. Information from the American College of Rheumatology notes that the immunosuppressant cyclophosphamide (Cytoxan) is used for severe complications of lupus. They also note that this medication may increase a person's risk of certain cancers, including: lymphoma skin cancer bladder cancer Research from 2017 found that the increased cancer risk of cyclophosphamide may occur when it is given at higher doses. Additionally, researchers found that hydroxychloroquine, another immunosuppressant used to treat lupus, may reduce a person's cancer risk when given at low doses. If a person has lupus, they should speak with their doctor about the risks and benefits of their treatments. Although lupus and leukemia are different conditions, they do have some overlapping symptoms. These shared symptoms include: fatigue fever weight loss petechiae, which are tiny red dots on the skin joint pain swollen glands dizziness A person should speak with their doctor if they notice any signs of lupus or leukemia. If a person has lupus, they should speak with their doctor if they notice any new or concerning symptoms. shortness of breath during physical activities paleness frequent infections bruising easily prolonged bleeding from cuts frequent or severe nosebleeds bleeding gums heavier or more frequent menstrual bleeding night sweats enlarged spleen or liver feeling of pain or fullness below the ribs wheezing coughing painful breathing Lupus and leukemia are both conditions that affect a person's immune system. If a person has lupus, they may be more likely to develop certain cancers. These may include leukemia. Researchers are not currently sure what the link is between lupus and leukemia. They believe lupus may increase a person's risk of cancer by weakening the immune system. Additionally, certain treatments for lupus may increase cancer risk. Both lupus and leukemia share certain symptoms. If a person notices any symptoms of either condition, they should speak with a doctor. A person with lupus should speak with their doctor if they notice any signs of leukemia, such as prolonged bleeding from cuts. Leukemia Lupus Blood / Hematology Cancer / Oncology Medical News Today has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. BalajiSubramanian S, et al. A rare case of dual metachronous primary malignancies, chronic myeloid leukemia, and tongue carcinoma in a patient with long-standing systemic lupus erythematosus: A case report and review of literature. Cyclophosphamide (Cytoxan). (2024). Guo J, et al. (2020). The relationship between cancer and medication exposure in patients with systemic lupus erythematosus: A nested case-control study. Hsu C-Y, et al. (2017). Cumulative immunosuppressant exposure is associated with diversified cancer risk among 14 832 patients with systemic lupus erythematosus: A nested case–control study. Leukemia. (n.d.). Leukemia—patient version. (n.d.). Lupus. (2024). Medications used to treat lupus. (2023). Signs and symptoms. (n.d.). Song L, et al. (2018). The risks of cancer development in systemic lupus erythematosus (SLE) patients: A systematic review and meta-analysis. Suzuki E, et al. (2023). Systemic lupus erythematosus and antiphospholipid syndrome accompanied by mixed-type autoimmune hemolytic anemia. Systemic lupus erythematosus. (2022). Systemic lupus erythematosus (Lupus). (2022). Zhang Y, et al. (2022). Hematological malignancies in systemic lupus erythematosus: Clinical characteristics, risk factors, and prognosis—a case-control study.

Legendary Australian musician shares heartbreaking details about his cancer battle
Legendary Australian musician shares heartbreaking details about his cancer battle

Daily Mail​

time25-05-2025

  • Entertainment
  • Daily Mail​

Legendary Australian musician shares heartbreaking details about his cancer battle

Legendary Australian musician Bob 'Bongo' Starkie has revealed heartbreaking details about his cancer battle. The 72-year-old, who shot to fame as a member of chart-topping Melbourne band Skyhooks in the 1970s, was diagnosed with aggressive leukemia. The shock news came as Bob's band were celebrating their seminal album Living In the 70's re-entering the ARIA top ten in January. And now Bongo is set to return to the stage to perform after cancelling his scheduled gigs in February. This is despite battling what he calls 'side health issues', including bleeding on the brain and leg clots. From A-list scandals and red carpet mishaps to exclusive pictures and viral moments, subscribe to the DailyMail's new showbiz newsletter to stay in the loop On top of receiving cancer therapy, Bob also had to endure an eye operation and a bout of sepsis which led to seven days in intensive care. In an interview with the Herald Sun, the famed guitarist paid tribute to fans who donated a whopping $25,000 via GoFundMe to help him finance his medical care. 'It has been amazing because all these people have anonymously donated all this dough,' Bob said. 'It has taken a bit of the stress and pressure off and allowed me to get rid of my credit cards and reduce my debt and just get on with things.' Bob hit the stage on Saturday for the Legends of Countdown show on the Gold Coast. Meanwhile, Indiana, the musician's daughter, who set up Bob's GoFundMe page described her father's recent health journey as 'pretty scary'. She told the publication that while her dad was hospitalised for weeks he got through the experience by watching Married at First Sight and the ABCs Hard Quiz. 'He needed to have a laugh, so we would watch Hard Quiz and MAFS with him', she said. It comes after Bob took to Facebook in March to reveal that his prognosis was good. He shared a photo that showed him standing wth his daughter Indiana and fellow Aussie music legend Wilbur Wilde. Captioning the happy snap, Bob was pleased to reveal that he is currently in remission. 'I'm heading home from hospital,' Bob wrote in the post. 'It's been six weeks and a bit of a wild ride. But my blood counts are good and the Leukemia is in remission. Still a way to go.' Skyhooks exploded onto the Aussie pop charts with their seminal 1974 debut album Living In The 70's. The band were known for their flamboyant costumes and makeup and their lyrics which often referenced Australian places and culture. Never a band that was afraid to court controversy, six of the album's ten tracks were banned from radio due to questionable lyric content. Despite this, the track You only Like Me Cos I'm Good In Bed was the first song played by your station Double J (later Triple J) when it debuted in January 1975. The album went on to spend 16 weeks at the top of the Australian charts, becoming the highest-selling album by a home grown act at the time. In 2011, the iconic album was added to the National Film and Sound Archive of Australia's Sounds of Australia registry. The band went on to release four more studio albums, including 1975's Ego Is Not A Dirty Word and 1976's Straight in A Gay Gay World. Bob's diagnosis comes after his brother Peter, also a member of Skyhooks, died in 2020 after falling off a ladder at his home in Victoria.

North Texas grandfather organizes fundraiser for his 3-year-old granddaughter
North Texas grandfather organizes fundraiser for his 3-year-old granddaughter

CBS News

time23-05-2025

  • Health
  • CBS News

North Texas grandfather organizes fundraiser for his 3-year-old granddaughter

The grandfather of a North Texas girl who is fighting a deadly disease is doing what he does best to help her get the treatment she needs. A fundraiser called 'Mudbugs for Mabel', scheduled for Saturday, May 24, in Lewisville, will hopefully raise money for medical expenses that the 3-year-old girl's family needs. "It's kind of hard to explain leukemia to a 3-year-old so we're using the term the big sick," said Mabel's mother Sarah Manchey. The 3-year-old was diagnosed with cancer in April, forcing her mother, a kindergarten teacher, to take leave from work because Mabel needs regular chemotherapy treatments. The medicine and other treatments Mabel needs are costly. "It definitely has us a little concerned, but you do what you do for your kids, but you figure it out, and you make it work," said Manchey. Mabel's grandfather owns a Cajun food store in Lewisville, where someone suggested a crawfish boil as a fundraiser for the family. "I went 'oh my gosh that's a fantastic idea' so it was a God thing," said Mabel's grandfather Billy Howell. 'Mudbugs for Mabel will be on Saturday, May 24th from 12 p.m. to 5 p.m. at The Cajun Turkey Company. "When he suggested the idea, I thought it was awesome, it's our favorite time of year with crawfish," said Manchey. Mabel plans to be there wearing a smile and what's become her signature pink chemo cap. A family relying on a love for each other and a love of crawfish to help a little girl overcome 'the big sick.'

Warning issued for common energy drink ingredient that elevates risk of blood cancer
Warning issued for common energy drink ingredient that elevates risk of blood cancer

The Independent

time21-05-2025

  • Health
  • The Independent

Warning issued for common energy drink ingredient that elevates risk of blood cancer

A recent study published in Nature has raised concerns about taurine, a widely used amino acid in energy drinks such as Red Bull and Celsius, indicating it may increase the risk of blood cancers. Researchers at the University of Rochester's Wilmot Cancer Institute discovered that leukemia cells absorb taurine, which develops in bone marrow, using it to fuel their growth through a process called glycolysis. This is the process where cells break down glucose to produce energy, which cancer cells use to grow. While taurine is naturally produced in the human body and found in foods such as meat and fish, it is also added to many energy drinks for its purported benefits, such as improving mental performance and reducing inflammation. It has also been used to alleviate chemotherapy side effects in leukemia patients. However, the study suggests that the excessive intake of taurine, particularly through supplements and energy drinks, could exacerbate leukemia by providing additional fuel for cancer cells. The study looked at mice with a special gene called SLC6A6, which helps move taurine around the body. Scientists also gave these mice human leukemia cells to see how they would react. They discovered that healthy bone marrow cells produce taurine, which the SLC6A6 gene then transports to the leukemia cells, potentially helping them grow. The researchers emphasized the need to weigh the risks and benefits of extra taurine for leukemia patients and energy drink consumers, given its widespread availability. Although the study is still early, researchers are hopeful that blocking taurine in leukemia cells could lead to new treatment options. The study is part of a larger effort to find whether taurine may also contribute to the spike of other cancers, such as colorectal cancer. The American Cancer Society projects that over 192,000 Americans will receive a diagnosis of blood cancer in 2025. This includes an estimated 66,890 new leukemia cases, 89,070 new lymphoma cases, and 36,110 new myeloma cases.

Common energy drink ingredient linked to blood cancer, People reports
Common energy drink ingredient linked to blood cancer, People reports

Yahoo

time19-05-2025

  • Business
  • Yahoo

Common energy drink ingredient linked to blood cancer, People reports

A common energy drink ingredient has been linked to the progression of the blood cancer leukemia, prompting researchers to voice concerns about the consumption of those beverages, People's Cara Lynn Shultz reports. Taurine – an amino acid that occurs naturally in proteins like meat and fish – is a common ingredient in energy drinks like Red Bull. As the Mayo Clinic explains it can help balance fluids, salts and minerals. But according to research published in Nature, taurine may promote leukaemogenesis – the development of leukemia cells – and 'identifies taurine as a key regulator of myeloid malignancies,' which, like leukemia, are cancers that begin in the blood, the author notes. Publicly traded companies in the space include Monster Beverage (MNST) and Celsius (CELH). Easily unpack a company's performance with TipRanks' new KPI Data for smart investment decisions Receive undervalued, market resilient stocks straight to you inbox with TipRanks' Smart Value Newsletter Published first on TheFly – the ultimate source for real-time, market-moving breaking financial news. Try Now>> See the top stocks recommended by analysts >> Read More on MNST: Disclaimer & DisclosureReport an Issue Monster Beverage price target raised to $56 from $50 at Roth Capital Monster Beverage upgraded to Outperform from Market Perform at CICC Monster Beverage's Earnings Call: Growth Amid Challenges Monster Beverage: Hold Rating Amid Mixed Performance and Valuation Concerns Monster Beverage: Hold Rating Amid Mixed Performance and Market Uncertainties

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