3 days ago
New weight loss pill could burn fat without usual jab side effects
A new experimental diet pill for type 2 diabetes and obesity works by triggering muscle metabolism to burn fat, offering a different approach to existing GLP-1 injections.
Unlike current weight loss jabs, this tablet-form drug aims to avoid common side effects such as gastrointestinal issues, loss of appetite, and reduced muscle mass.
Initial animal studies and a small human clinical trial involving 48 healthy participants and 25 people with type 2 diabetes have shown the drug is well-tolerated and effective in controlling blood sugar and improving body composition.
Researchers from Karolinska Institutet and Stockholm University developed the drug, a modified beta-2 agonist, to specifically target muscles without overstimulating the heart.
The next phase involves a larger clinical study planned by Atrogi AB, the company developing the treatment, to further assess its efficacy and safety.