Latest news with #treatmentOptions
Medscape
21-05-2025
- Health
- Medscape
Ulcerative Colitis: Colectomy Risk Dips in the 21st Century
The risk for colectomy declined over the past two decades among Finnish patients with newly diagnosed ulcerative colitis (UC), particularly between 2013 and 2020, when several advanced treatment options were available. METHODOLOGY Researchers in Finland utilized data from a population-based registry between January 2000 and December 2020 to determine the risk for colectomy in patients with newly diagnosed UC and compare risks across different eras. They identified 32,108 patients, of whom 2195 underwent colectomy (median age at surgery, 39.4 years; 60.5% men); patients were stratified into three groups — 2000-2005 (prebiological era), 2006-2012, and 2013-2020 — according to the time of diagnosis and the availability of treatments. Participants were also stratified by age at diagnosis into paediatric (< 20 years), adult (20-59 years), and older adult (≥ 60 years) groups. TAKEAWAY: The cumulative risk for colectomy was 1.0% at 1 year, 4.7% at 5 years, and 7.3% at 10 years following UC diagnosis. Compared with the prebiological era, the 2013-2020 era saw a reduction in the 1-year and 5-year risks for colectomy (incidence rate ratio [IRR], 0.757 and 0.70, respectively), and the 2006-2012 era saw a reduction in the 10-year risk (IRR, 0.87). The paediatric population experienced a lower risk for surgery in the 2013-2020 era than in previous eras, whereas the risk for surgery among older adult patients remained unchanged from earlier periods. Compared with the adult population, the paediatric population faced a higher risk for surgery (IRR, 1.69), whereas the older adult population had a lower risk (IRR, 0.79). IN PRACTICE: "The risk of colectomy among Finnish UC patients has decreased in the 21st century. The risk reduction coincides with the use of advanced medical therapy and more ambitious treatment targets, and it can also be seen in children and adolescents. The elderly have lower colectomy rates than do younger newly diagnosed patients, but their risk has remained constant," the authors wrote. SOURCE: This study was led by Kristi Kontola, Department of Internal Medicine, Wellbeing Services County of South Ostrobothnia, Seinäjoki, Finland. It was published online on May 13, 2025, in the Journal of Crohn's and Colitis . LIMITATIONS: This study was limited by the lack of follow-up data and the use of non-inflammatory bowel disease registries. The Social Insurance Institution registry was not updated with clinical data after initial reimbursement approval; hence, it may have included misdiagnosed cases. Additionally, the national registries used in this study did not contain detailed clinical information, preventing the analysis of important parameters such as disease extent and specific indications for colectomy. DISCLOSURES: This study was supported by the Wellbeing Services County of South Ostrobothnia and the Mary and Georg C. Ehrnrooth Foundation. One author reported being a national representative of ECCO, a board member of the Finnish Society of Gastroenterology, and a member of the scientific advisory board of the Finnish Coeliac Society. Another author reported being a board member of the IBD subdivision of the Finnish Society of Gastroenterology and a consultant for the Nursing Research Foundation. Some also reported receiving personal fees from various pharmaceutical companies.
CNN
19-05-2025
- Climate
- CNN
Doctor explains possible treatment options for Biden's cancer
Doctor explains possible treatment options for Biden's cancer Former President Joe Biden was diagnosed with an 'aggressive form' of prostate cancer, according to a statement from his personal office, and it has spread to his bones. Dr. Jamin Brahmbhatt, a urologist from Orlando Health, explains the possible treatment options for the former president. 01:25 - Source: CNN Vertical Top News 17 videos Doctor explains possible treatment options for Biden's cancer Former President Joe Biden was diagnosed with an 'aggressive form' of prostate cancer, according to a statement from his personal office, and it has spread to his bones. Dr. Jamin Brahmbhatt, a urologist from Orlando Health, explains the possible treatment options for the former president. 01:25 - Source: CNN California fertility clinic damaged in explosion At least one person is dead and four others injured in a Palm Springs, California, explosion outside a fertility clinic, according to the FBI's assistant director in charge of Los Angeles' field office. CNN's Jessica Dean reports. 00:47 - Source: CNN Rare dust storm blankets Chicago The Chicago skyline disappeared momentarily as a wall of dust blew through the city. The National Weather Service attributed this to 60 to 70 mph winds that blew over dry farmlands, collecting dust and blowing it through the Chicago area, according to CNN affiliate WBBM. 00:32 - Source: CNN CNN correspondent walks through aftermath of deadly tornado A storm that produced a devastating tornado in the St. Louis, Missouri, area Friday afternoon has left multiple people dead, according to local authorities. CNN's Julia Vargas Jones walks through some of the aftermath where one resident said an entire floor to a nearby building was blown away. 00:44 - Source: CNN Zelensky says Putin was 'afraid' for talks Neither Ukrainian President Volodymyr Zelensky or Russian President Vladimir Putin are attending peace talks in Istanbul after days of confusion. In a meeting in Albania, Zelensky said Putin was 'afraid' to come to Turkey for talks and that Russian delegation in Istanbul is of a 'very low level.' 00:38 - Source: CNN Lawmakers fall asleep during hearing Republican Rep. Blake Moore and Democratic Rep. Debbie Dingell both appeared to fall asleep during what were at-times contentious debates over provisions in President Donald Trump's sweeping tax and spending cuts package. 01:01 - Source: CNN Springsteen criticizes Trump administration during show Bruce Springsteen has criticized President Trump's administration on stage during a performance at the start of his UK tour in Manchester. 01:15 - Source: CNN Zelensky warns 'no time for playing games' Ukrainian President Volodymyr Zelensky said he will head to Turkey and wait for Russian President Vladimir Putin for potential ceasefire talks; but he set some minimal goals for the meeting. CNN's Nick Paton Walsh reports. 01:26 - Source: CNN Mistaken arrest leads to teen's ICE detention A northwest Georgia community voted overwhelmingly for President Donald Trump. Now it's desperately trying to save its residents from being deported. CNN's Dianne Gallagher reports. See the full story on CNN tonight. 01:28 - Source: CNN Deepfake detectors fooled by expert With AI technology creating more and more realistic deepfakes, detectors are not up to the challenge of realizing what is real and what is fake, according to an industry expert. CNN's Isabel Rosales looks at how this technology can be bypassed and what you can do to protect yourself. An earlier version of this video gave the incorrect title for Perry Carpenter. He is the Chief Human Risk Management Strategist at KnowBe4. 02:41 - Source: CNN Arizona wildfire burns more than 2,000 acres A wildfire in Apache County, Arizona has burned more than 2,000 acres and destroyed multiple structures, with several areas under evacuation orders, according to the Arizona Department of Forestry and Fire Management. 00:30 - Source: CNN 200 people rescued from flooded Maryland school Roughly 200 people have been rescued from an elementary school in Maryland after heavy rains brought severe flooding to the region. Waters started to reach the second floor of Westernport Elementary School, according to the county's emergency services department. 00:39 - Source: CNN Syrians react after Trump says he plans to lift sanctions President Donald Trump announced he plans to lift sanctions on Syria during a speech in Saudi Arabia citing the fall of the Assad regime as grounds for the release of pressure on the country. Syrians spared little time before celebrating. 00:51 - Source: CNN Coates describes moment Cassie cried on the stand Cassie Ventura, the former girlfriend of Sean 'Diddy' Combs and one of his accusers, testified in his federal criminal trial. CNN's Laura Coates breaks down key moments from her testimony. 00:52 - Source: CNN New book reveals 'shocking' claim that Biden didn't recognize Clooney President Joe Biden did not recognize George Clooney when he arrived for a record-breaking June 2024 fundraiser the movie star was co-hosting, according to a forthcoming book from CNN's Jake Tapper and Axios' Alex Thompson. 01:06 - Source: CNN See Edan Alexander's reunion with family after release Edan Alexander, the last known living American hostage in Gaza, was released by Hamas and reunited with his family on Monday, ending an 18-month ordeal that began with the militant group's October 7 attack. 00:40 - Source: CNN
CNN
19-05-2025
- Climate
- CNN
Doctor explains possible treatment options for Biden's cancer
Doctor explains possible treatment options for Biden's cancer Former President Joe Biden was diagnosed with an 'aggressive form' of prostate cancer, according to a statement from his personal office, and it has spread to his bones. Dr. Jamin Brahmbhatt, a urologist from Orlando Health, explains the possible treatment options for the former president. 01:25 - Source: CNN Vertical Top News 17 videos Doctor explains possible treatment options for Biden's cancer Former President Joe Biden was diagnosed with an 'aggressive form' of prostate cancer, according to a statement from his personal office, and it has spread to his bones. Dr. Jamin Brahmbhatt, a urologist from Orlando Health, explains the possible treatment options for the former president. 01:25 - Source: CNN California fertility clinic damaged in explosion At least one person is dead and four others injured in a Palm Springs, California, explosion outside a fertility clinic, according to the FBI's assistant director in charge of Los Angeles' field office. CNN's Jessica Dean reports. 00:47 - Source: CNN Rare dust storm blankets Chicago The Chicago skyline disappeared momentarily as a wall of dust blew through the city. The National Weather Service attributed this to 60 to 70 mph winds that blew over dry farmlands, collecting dust and blowing it through the Chicago area, according to CNN affiliate WBBM. 00:32 - Source: CNN CNN correspondent walks through aftermath of deadly tornado A storm that produced a devastating tornado in the St. Louis, Missouri, area Friday afternoon has left multiple people dead, according to local authorities. CNN's Julia Vargas Jones walks through some of the aftermath where one resident said an entire floor to a nearby building was blown away. 00:44 - Source: CNN Zelensky says Putin was 'afraid' for talks Neither Ukrainian President Volodymyr Zelensky or Russian President Vladimir Putin are attending peace talks in Istanbul after days of confusion. In a meeting in Albania, Zelensky said Putin was 'afraid' to come to Turkey for talks and that Russian delegation in Istanbul is of a 'very low level.' 00:38 - Source: CNN Lawmakers fall asleep during hearing Republican Rep. Blake Moore and Democratic Rep. Debbie Dingell both appeared to fall asleep during what were at-times contentious debates over provisions in President Donald Trump's sweeping tax and spending cuts package. 01:01 - Source: CNN Springsteen criticizes Trump administration during show Bruce Springsteen has criticized President Trump's administration on stage during a performance at the start of his UK tour in Manchester. 01:15 - Source: CNN Zelensky warns 'no time for playing games' Ukrainian President Volodymyr Zelensky said he will head to Turkey and wait for Russian President Vladimir Putin for potential ceasefire talks; but he set some minimal goals for the meeting. CNN's Nick Paton Walsh reports. 01:26 - Source: CNN Mistaken arrest leads to teen's ICE detention A northwest Georgia community voted overwhelmingly for President Donald Trump. Now it's desperately trying to save its residents from being deported. CNN's Dianne Gallagher reports. See the full story on CNN tonight. 01:28 - Source: CNN Deepfake detectors fooled by expert With AI technology creating more and more realistic deepfakes, detectors are not up to the challenge of realizing what is real and what is fake, according to an industry expert. CNN's Isabel Rosales looks at how this technology can be bypassed and what you can do to protect yourself. An earlier version of this video gave the incorrect title for Perry Carpenter. He is the Chief Human Risk Management Strategist at KnowBe4. 02:41 - Source: CNN Arizona wildfire burns more than 2,000 acres A wildfire in Apache County, Arizona has burned more than 2,000 acres and destroyed multiple structures, with several areas under evacuation orders, according to the Arizona Department of Forestry and Fire Management. 00:30 - Source: CNN 200 people rescued from flooded Maryland school Roughly 200 people have been rescued from an elementary school in Maryland after heavy rains brought severe flooding to the region. Waters started to reach the second floor of Westernport Elementary School, according to the county's emergency services department. 00:39 - Source: CNN Syrians react after Trump says he plans to lift sanctions President Donald Trump announced he plans to lift sanctions on Syria during a speech in Saudi Arabia citing the fall of the Assad regime as grounds for the release of pressure on the country. Syrians spared little time before celebrating. 00:51 - Source: CNN Coates describes moment Cassie cried on the stand Cassie Ventura, the former girlfriend of Sean 'Diddy' Combs and one of his accusers, testified in his federal criminal trial. CNN's Laura Coates breaks down key moments from her testimony. 00:52 - Source: CNN New book reveals 'shocking' claim that Biden didn't recognize Clooney President Joe Biden did not recognize George Clooney when he arrived for a record-breaking June 2024 fundraiser the movie star was co-hosting, according to a forthcoming book from CNN's Jake Tapper and Axios' Alex Thompson. 01:06 - Source: CNN See Edan Alexander's reunion with family after release Edan Alexander, the last known living American hostage in Gaza, was released by Hamas and reunited with his family on Monday, ending an 18-month ordeal that began with the militant group's October 7 attack. 00:40 - Source: CNN
