
Medical trial for penis cancer 'gave me two more years'
Mr Baker told the BBC his cancer had been caught late because it took over a year for him to come forward with his symptoms. The NHS says symptoms can include bleeding, a rash, a lump or growth, and a change in skin colour."It didn't look very good," Mr Baker said. "The actual swelling got bigger and bigger and then I was trying to get somewhere to get my life sorted out and find out what it was. It was too late."He had to have an amputation and has been left with incurable cancer. Consultant oncologist and chief investigator of the EPIC study, Professor Amit Bahl, said the stigma around such symptoms often leads to late diagnosis.He said: "In cancers like these, there is no support system, you can't go out and talk about it because most patients have never heard you can get cancer in the penis. "If you ask ladies, they have heard about cancer in the cervix, in the vagina, but cancer in the penis never gets talked about."The immunotherapy treatment used in the trial is not available on the NHS, but Professor Bahl is applying to the Cancer Drugs Fund to pay for the small number patients who may benefit.
Using immunotherapy to treat cancer is still considered by doctors to be a relatively new approach.But more than 60 per cent of the patients in the trial, who all had advanced penile cancer, were found to have had a clinical benefit.Among these patients, predicted lifespans increased to 15 months on average.Professor Bahl said: "Our aim is to improve outcomes in this rare cancer, which has limited treatment options."Penile cancer can be a very aggressive disease, but this study shows we might be able to give men a little more time."Penile cancer is rare, and it usually presents externally first, so when patients are diagnosed, early treatments which can cure the cancer are possible."The trial has proved so successful that Professor Bahl is now planning to start another trial to give immunotherapy at an earlier stage of the disease, in the hope that it will improve cure rates.
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The Independent
23 minutes ago
- The Independent
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BBC News
24 minutes ago
- BBC News
Yorkshire doctors join national five-day strike
Resident doctors, formerly known as junior doctors, across Yorkshire are taking part in a national five-day strike after the government failed to agree a pay deal with their of the British Medical Association (BMA), who work in hospitals across the region, joined others across England in the walkout, which began at 07:00 BST on leader Dr Tom Dolphin said: "We are very sorry that strikes have become necessary."Meanwhile, Health Secretary Wes Streeting said he did not believe the BMA had "engaged with me in good faith" over bids to avert the strike. This year resident doctors are getting an average pay rise of 5.4%, following a 22% increase over the previous two the BMA said wages were still around 20% lower in real terms than in 2008, even after an increase in August. 'My heart is always at work' Speaking from the picket line outside Leeds General Infirmary (LGI), Cristina Costache, who is a paediatrics registrar at LGI and a PhD student, said the walkout had been "a lot better supported than I thought it would be - it's actually really well supported".However, Dr Costache said striking had been a "very difficult decision to make".She said: "I get depressed if I'm not in work. My heart is always at work. "But I also care about my colleagues and my profession, and what we're really feeling is the gaps."There's always a gap on the paediatric registrar rota. 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'A last resort' Dr Stella Chatzieleftheriou, a UK resident doctors committee representative from Sheffield, said she was worried about the "sustainability" of the medical workforce at the current wages."I've seen dozens of colleagues leave the country and relocate to New Zealand and Australia and they don't have any plans to return," she said."The only way to retain the doctors we have already, and hopefully bring some back, is to offer a pay that is close to comparable."Dr Chatzieleftheriou said strike action had been a "last resort".The strike's core, she said, was a "concern for long-term patient safety if we can't keep the workforce we have and bring back doctors that we have lost over the years".She concluded: "Ultimately you need a well-paid, motivated and happy work force."That, in the long term, will improve outcomes for patient care." 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"Being an ex-firefighter for 30 years, I've been involved in strikes, it's the only way that the government will listen."However, he said he thought the rise asked for was too much."I do think what they're asking for is a bit excessive. I think they need to go in with a lower percentage. "I mean 22% over two years is a good raise. But for the job that they do I think it is a fair percentage." 'Patient safety at risk' Psychology student Freya Wallace, 20, said she agreed doctors deserved to be paid said: "I think it's fair that they should get more pay. If that's what they've got to do to get the money that they deserve, then I think that's fair enough."She said: "If it was any other profession, people would have no problem with it."However, she said the strike would "absolutely put patient safety at risk". "But I think people get better treatment when doctors are less overworked and better paid," she said."So I think in the long term it would really benefit patients." 'It's totally wrong' Jan Palmer, 62, from Wakefield, said she had recently been diagnosed with cancer and worried the strike would affect the speed of her described the strike as "totally wrong"."I've just had a conversation with a person who's had a serious motorbike accident," she said."He should have been seen tomorrow and his next appointment now is September."I just don't understand how they can leave people like that."She added: "I've just found out I have breast cancer, I've been seen within four weeks."I've got to have surgery. I'm only hoping now that this won't affect my surgery."And I do feel sorry for them, the nurses as well, but there's only so much we've got in the pot." Streeting said the NHS would face a challenging few days during the doctors' strike as it strived to keep as many services as possible after the walkout began he said it was not possible to eliminate disruption, but it was "being kept to a minimum". Listen to highlights from West Yorkshire on BBC Sounds, catch up with the latest episode of Look North.


BBC News
24 minutes ago
- BBC News
Graham Thorpe 'not perceived' to be in crisis situation
Former England cricketer Graham Thorpe was not perceived by healthcare professionals to be in a "crisis situation" after they were told he had asked his wife "for help to end his life" weeks before he died, an inquest has 55-year-old was regarded as one of the best English players of his died on the morning of 4 August 2024 after being struck by a train at a railway station in inquest at Surrey Coroner's Court in Woking heard he had "spiralled into depression" after losing his job as a batting coach, and he had tried to take his own life on another occasion. After Mr Thorpe missed an appointment with the community mental health team on 28 June 2024, care co-ordinator Katie Johnson spoke to Mrs Thorpe on the phone, who said her husband was "constantly asking for help to end his life", the court Johnson then spoke to Mr Thorpe who told her he "hadn't been out for a while" and "didn't see the point of being here" but had no immediate plans to act on suicidal thoughts, the inquest investigation was carried out by Surrey and Borders Partnership NHS Foundation Trust after his Shriti Burgul, a consultant psychiatrist who reviewed the investigation's report before it was finalised, told the court on Friday one of the findings was "it was noted Mr Thorpe's presentation at his appointment on 28 June 2024 was in keeping with previous presentations and not perceived by the team as a crisis situation". Asked if arranging an appointment in two weeks was an appropriate response, Dr Burgul said that in the absence of Mr Thorpe expressing "active intent" or an "active plan" it would be appropriate to allow two told the court Mr Thorpe was not at the level of requiring intervention from the home treatment psychiatrist was asked if there was any evidence that - if there had been an in-person assessment for Mr Thorpe - there would have been a different outcome, and she replied "no".The investigation noted a letter from when Mr Thorpe was discharged from a private hospital in July 2022, which said a neuropsychologist should be identified to provide further support, the inquest heard. 'A real shock' Given the conversation was over the phone, the psychiatrist was asked if it would have been appropriate to arrange to see Mr Thorpe very told the court: "In the wisdom of hindsight, then yes, a home visit would have been clinically indicated."This was never done by the private provider or the GP, and a risk panel advised it should be explored in June 2024, Dr Burgul told the court. Asked whether there was any neuropsychological impact that could have affected the cricketer's ability to engage in appointments, given he missed some, the psychiatrist said: "It's a possibility, yes".Mr Thorpe's cause of death was recorded by a pathologist as multiple injuries, the coroner widow said the termination of his employment with the England and Wales Cricket Board had been a "real shock to Graham", which was the "start of the decline of his mental health".The inquest by PA Media If you have been affected by any of the issues in this story, help and support is available at BBC Action Line.