Physician and New York Times Best-Selling Author Dr. Michael Greger Releases New Longevity Cookbook: THE HOW NOT TO AGE COOKBOOK
In his New York Times Best Seller, How Not to Age, Dr. Greger revealed that diet can help regulate every one of the most promising strategies for combating the effects of aging. His Anti-Aging Eight streamlined evidence-based research into simple, accessible steps for ensuring physical and mental longevity. Now, in The How Not to Age Cookbook, decades of scientific research are put to use in more than a hundred wholesome recipes.
Each of the simple, nutrition-packed dishes uses ingredients that have been associated with a healthy lifespan, with inspiration from the places around the world where people traditionally live the longest. Grounded in the latest nutrition science, The How Not to Age Cookbook bursts with delicious meals, snacks, beverages, and desserts that will help keep the body and mind nourished and youthful.
For more information on The How Not to Age Cookbook and the latest information on evidence-based nutrition and health, visit www.nutritionfacts.org.
Michael Greger, M.D. FACLM, is a physician, New York Times best-selling author, founder of NutritionFacts.org, founding member and Fellow of the American College of Lifestyle Medicine, and internationally-recognized speaker on nutrition, food safety, and public health issues. He is a graduate of Cornell University School of Agriculture and Tufts University School of Medicine. All proceeds received from his books and speaking engagements are donated to charity.
NutritionFacts.org is a non-profit, strictly non-commercial, science-based public service organization that provides free updates on the latest in nutrition research. More than 2,000 videos on nearly every aspect of healthy eating are available on its website, with new videos and articles uploaded daily. NutritionFacts.org is a proud member of the True Health Initiative, a global voice for lifestyle as medicine. Information regarding Dr. Greger's New York Times Best-Selling books How Not to Die, How Not to Diet, and How Not to Age, his free Daily Dozen app, and podcast are also available on NutritionFacts.org.
Contact:Mary Harris, Media Directormharris@nutritionfacts.org
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GnRH Antagonists Market on Upward Trajectory During the Forecast Period (2025-2034) Across the 7MM
The GnRH inhibitor market is shifting toward more convenient, patient-focused treatments, driven by oral therapies such as ORGOVYX and YSELTY. As the pipeline continues to grow and indications expand, this drug class is poised for broader clinical use and is likely to play a key role in the future of hormonal suppression in oncology and women's health. LAS VEGAS, Aug. 13, 2025 /PRNewswire/ — DelveInsight's GnRH Receptor Antagonists Market Size, Target Population, Competitive Landscape & Market Forecast report includes a comprehensive understanding of current treatment practices, addressable patient population, which includes top indications such as Endometriosis, fibroids, prostate cancer, and others. The selected indications are based on approved therapies and ongoing pipeline activity. The report also provides insights into the emerging GnRH receptor antagonists, market share of individual therapies, and current and forecasted market size from 2020 to 2034, segmented into 7MM. Key Takeaways from the GnRH Receptor Antagonists Market Report As per DelveInsight's analysis, the total market size of GnRH receptor antagonists in the 7MM is expected to surge significantly by 2034. The report provides the total potential number of patients in the indications, such as Endometriosis, fibroids, prostate cancer, and others. Leading GnRH receptor antagonist companies, such as Debiopharm, Tiumbio, Antev, and others, are developing novel GnRH Receptor Antagonists that can be available in the GnRH receptor antagonist market in the coming years. Some of the key GnRH receptor antagonists in the pipeline include Debio 4326, Merigolix (TU2670), Teverelix, and others. In May 2025, TiumBio and Daewon Pharmaceutical completed Phase II clinical trial of 'Merigolix (TU2670/DW4902)' for Uterine Fibroids with positive results. In March 2025, Kissei initiated the Phase III Clinical Trial for the GnRH Antagonist 'Linzagolix' indicated for Endometriosis in Japan. In February 2025, Kissei submitted New Drug Application (NDA) for 'linzagolix' indicated for Uterine Fibroids in Japan. In the EU, linzagolix received marketing authorization for uterine fibroids in June 2022. Discover which indication is expected to grab the major GnRH receptor antagonists market share @ GnRH Receptor Antagonists Market Report GnRH Receptor Antagonists Market Dynamics The GnRH receptor antagonists market is witnessing steady growth driven by advancements in therapeutic applications across a range of hormone-related disorders. These antagonists function by directly inhibiting GnRH receptors in the pituitary gland, thereby suppressing the release of LH and FSH. This mechanism provides a rapid and reversible suppression of sex hormones such as testosterone and estrogen, making them effective alternatives to GnRH agonists, which are associated with an initial hormone surge. Key indications for GnRH receptor antagonists include prostate cancer, endometriosis, uterine fibroids, and assisted reproductive technologies (ART). One of the significant drivers of market expansion is the growing prevalence of hormone-sensitive cancers, particularly prostate cancer in men and endometriosis or uterine fibroids in women. The increasing demand for therapies with improved safety profiles and faster onset of action has created a favorable environment for GnRH antagonists. Moreover, recent product launches such as RELUGOLIX (marketed as ORGOVYX for prostate cancer and MYFEMBREE for uterine fibroids) and ELAGOLIX (marketed as ORILISSA for endometriosis and ORIAHNN for fibroids) have gained regulatory approvals and demonstrated commercial success, further validating the therapeutic potential of this class. Additionally, the market is benefiting from a broader shift towards oral therapies. Unlike older GnRH agonists, many of the newer antagonists are available in oral formulations, improving patient adherence and convenience. This factor is particularly significant in chronic indications where long-term management is necessary. The preference for non-invasive treatment options among patients and providers is reshaping treatment paradigms and expanding the reach of GnRH antagonists beyond hospital settings to outpatient care. However, the market also faces certain challenges. Cost of therapy remains a barrier in several regions, particularly in low- and middle-income countries, where access to advanced hormonal therapies is limited. Furthermore, competition from alternative treatment modalities such as aromatase inhibitors, progestins, and surgical interventions can restrict market penetration in some indications. Intellectual property protection, regulatory requirements, and long development timelines can also impact new entrants and biosimilar competition. In the coming years, continued R&D in expanding the therapeutic use of GnRH antagonists, including potential applications in breast cancer, male infertility, and transgender hormone therapy, is likely to support further market growth. Strategic collaborations, licensing deals, and increasing investments by pharmaceutical companies in reproductive health and oncology are expected to drive innovation and market competitiveness. Overall, the GnRH receptor antagonists market is positioned for sustained growth, underpinned by clinical efficacy, patient-centric delivery formats, and expanding disease awareness. GnRH Receptor Antagonists Treatment Market The introduction of oral GnRH antagonists, known for their rapid onset of action, is reshaping treatment approaches for several prevalent gynecologic and oncologic conditions such as endometriosis, uterine fibroids, and prostate cancer. Over the past decade, the GnRH inhibitor market has undergone a significant transformation, moving from injectable formulations to more convenient oral therapies. Initially, the market was led by FIRMAGON, an injectable GnRH antagonist approved in 2008 for advanced prostate cancer. However, a major turning point came in 2020 with the approval of ORGOVYX by Sumitomo Pharma—the first oral GnRH antagonist for prostate cancer. ORGOVYX marked a clinical advancement by eliminating the testosterone flare linked with GnRH agonists and improving patient convenience by removing the need for injections. Its rapid adoption in androgen deprivation therapy (ADT) highlighted a growing preference for oral options. Another significant development was the approval of YSELTY (linzagolix) in 2022 by the EMA for treating uterine fibroids and endometriosis. Developed by Theramex and Kissei, YSELTY extended the use of GnRH antagonists into women's health, offering a once-daily oral therapy with customizable suppression levels to help mitigate long-term estrogen deficiency effects. This approval further validated the use of oral GnRH inhibitors beyond oncology and underscored their expanding role in broader therapeutic areas. Learn more about the GnRH receptor antagonists @ GnRH Receptor Antagonists Analysis Key Emerging GnRH Receptor Antagonists and Companies Key players in the GnRH receptor antagonist market include Tiumbio (Merigolix), Antev (Teverelix), Debiopharm (Debio 4326), and others. Debio 4326 is an innovative, injectable, and biodegradable formulation of triptorelin, designed to provide extended-release over 12 months for managing central precocious puberty (CPP). Its key advantage lies in significantly reducing injection frequency, thereby easing the treatment experience for children with this rare condition. Developed based on positive efficacy and safety data from existing 1-, 3-, and 6-month triptorelin products, this new version aims to enhance long-term adherence and minimize the emotional and physical stress on both children and their caregivers. Debio 4326 is currently undergoing a Phase 3 clinical trial across North and South America to assess its efficacy and safety. Teverelix is a long-acting, injectable GnRH antagonist formulated using a novel microcrystal technology that addresses the known safety limitations of earlier GnRH antagonist treatments for prostate cancer. With favorable injection site tolerance and a six-week dosing schedule, Teverelix is positioned to offer better patient compliance and improved treatment outcomes. Beyond prostate cancer, it also holds potential for treating benign prostate hyperplasia (BPH), acute urinary retention (AUR), endometriosis, and uterine fibroids. In January 2023, the U.S. FDA reviewed early-stage clinical data (Phase I and IIa) and provided written feedback on the design of Antev's planned Phase III trial for Teverelix, targeting patients with advanced prostate cancer and high cardiovascular risk—an area with significant unmet clinical need. Subsequently, in December 2023, the FDA approved a Phase IIb trial involving 40 patients with advanced prostate cancer. In November 2024, the agency also approved another Phase IIb study for acute urinary retention, set to enroll 390 patients. These regulatory milestones support Antev's broader strategy to advance Teverelix as a targeted therapy for patients with specific medical needs. The anticipated launch of these emerging therapies are poised to transform the GnRH receptor antagonists market landscape in the coming years. As these cutting-edge therapies continue to mature and gain regulatory approval, they are expected to reshape the GnRH receptor antagonists market landscape, offering new standards of care and unlocking opportunities for medical innovation and economic growth. To know more about GnRH receptor antagonists clinical trials, visit @ GnRH Receptor Antagonists Treatment GnRH Receptor Antagonists Overview GnRH antagonists mark a notable improvement in androgen deprivation therapy (ADT) for treating hormone-sensitive prostate cancer. These drugs function by directly inhibiting GnRH receptors in the pituitary gland, which quickly suppresses the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to a rapid drop in testosterone levels. This direct mechanism avoids the initial testosterone surge, or 'flare', that is often seen with other forms of ADT. A major clinical benefit of GnRH antagonists is their swift action, with testosterone levels typically reaching castration thresholds within days. This rapid hormonal suppression is especially beneficial for patients with metastatic or symptomatic disease who require immediate control. Moreover, GnRH antagonists have shown better cardiovascular safety compared to traditional treatments. For instance, the HERO trial demonstrated that relugolix, a once-daily oral GnRH antagonist, significantly reduced the risk of major cardiovascular events. As a result, these agents are particularly advantageous for patients with existing heart-related conditions. GnRH Receptor Antagonists Epidemiology Segmentation The GnRH receptor antagonists market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM, segmented into: Total Cases in Selected Indications for GnRH Receptor Antagonist Total Eligible Patient Pool for GnRH Receptor Antagonist in Selected Indications Total Treated Cases in Selected Indications for GnRH Receptor Antagonist GnRH Receptor Antagonists Report Metrics Details Study Period 2020–2034 GnRH Receptor Antagonists Report Coverage 7MM [The United States, the EU-4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan] Key Indications Covered in the Report Endometriosis, fibroids, prostate cancer, and others Key GnRH Receptor Antagonist Companies Debiopharm, Tiumbio, Antev, Ferring Pharmaceuticals, Sumitomo Pharma, Theramex, Kissei, and others Key GnRH Receptor Antagonists Debio 4326, Merigolix (TU2670), Teverelix, FIRMAGON, ORGOVYX, YSELTY, and others Scope of the GnRH Receptor Antagonists Market Report GnRH Receptor Antagonists Therapeutic Assessment: GnRH Receptor Antagonists' current marketed and emerging therapies GnRH Receptor Antagonists Market Dynamics: Conjoint Analysis of Emerging GnRH Receptor Antagonists Drugs Competitive Intelligence Analysis: SWOT analysis and Market entry strategies Unmet Needs, KOL's views, Analyst's views, GnRH Receptor Antagonists Market Access and Reimbursement Discover more about GnRH receptor antagonists in development @ GnRH Receptor Antagonists Clinical Trials Table of Contents 1 Key Insights 2 Report Introduction 3 Executive Summary of GnRH Receptor Antagonist 4 Key Events 5 Epidemiology and Market Forecast Methodology 6 GnRH Receptor Antagonist Market Overview at a Glance in the 7MM 6.1 Market Share (%) Distribution by Therapies in 2024 6.2 Market Share (%) Distribution by Therapies in 2034 6.3 Market Share (%) Distribution by Indications in 2024 6. Market Share (%) Distribution by Indications in 2034 7 GnRH Receptor Antagonist: Background and Overview 7.1 Introduction 7.2 Treatment 8 Target Patient Pool 8.1 Key Findings 8.2 Assumptions and Rationale: 7MM 8.3 Epidemiology Scenario in the 7MM 8.4 Total Cases in Selected Indications for GnRH Receptor Antagonist in the 7MM 8.5 Total Eligible Patient Pool for GnRH receptor antagonist in Selected Indications in the 7MM 8.6 Total Treated Cases in Selected Indications for GnRH Receptor Antagonist in the 7MM 9 Marketed Therapies 9.1 Key Competitors 9.2 FIRMAGON (degarelix): FERRING PHARMACEUTICALS 9.2.1 Product Description 9.2.2 Regulatory milestones 9.2.3 Other developmental activities 9.2.4 Clinical development 9.2.5 Safety and efficacy 9.3 ORGOVYX (relugolix): Sumitomo Pharma List to be continued in the report 10 Emerging Therapies 10.1 Key Competitors 10.2 Debio 4326: Debiopharm 10.2.1 Product Description 10.2.2 Other developmental activities 10.2.3 Clinical development 10.2.4 Safety and efficacy 10.2.5 Analyst Views 10.3 Teverelix: Antev List to be continued in the report 11 GnRH Receptor Antagonist: Seven Major Market Analysis 11.1 Key Findings 11.2 Market Outlook 11.3 Conjoint Analysis 11.4 Key Market Forecast Assumptions 11.4.1 Cost Assumptions and Rebates 11.4.2 Pricing Trends 11.4.3 Analogue Assessment 11.4.4 Launch Year and Therapy Uptakes 11.5 Total Market Size of GnRH receptor antagonist in the 7MM 11.6 Market Size of GnRH Receptor Antagonist by Indication in the 7MM 11.7 Market Size of GnRH Receptor Antagonist by Therapies in the 7MM 11.8. The United States Market Size 11.8.1 Total Market Size of GnRH Receptor Antagonists in the United States 11.8.2 Market Size of GnRH Receptor Antagonist by Therapies in the United States 11.9 EU4 and the UK Market Size 11.10 Japan Market Size 12 Market Access and Reimbursement 13 SWOT Analysis of GnRH Receptor 14 KOL Views of GnRH Receptor 15 Unmet Needs of GnRH Receptor 16 Bibliography 17 Report Methodology Related Reports Prostate Cancer Market Prostate Cancer Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key prostate cancer companies, including Sanofi, AstraZeneca, Astellas Pharma, Bayer, Novartis, Curium, Merck, Orion, Janssen Pharmaceutical, Pfizer, Exelixis, Ipsen Pharma, Takeda, AB Science, Lantheus, Eli Lilly, POINT Biopharma, Telix Pharmaceuticals, Tavanta Therapeutics, Jiangsu Hengrui Pharmaceuticals, Kangpu Biopharmaceuticals, Fusion Pharma, Merus, Bristol-Myers Squibb, Syntrix Pharmaceuticals, Promontory Therapeutics, Xencor, Taiho Pharmaceutical, Madison Vaccines, MacroGenics, Zenith Epigenetics, Modra Pharmaceuticals, Arvinas, Laekna Therapeutics, Blue Earth Therapeutics, Oncternal Therapeutics, Essa Pharma, Clarity Pharmaceuticals, BioNTech, DualityBio, Daiichi Sankyo, Fortis Therapeutics, ORIC Pharmaceuticals, Amgen, among others. Prostate Cancer Pipeline Prostate Cancer Pipeline Insight – 2025 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key prostate cancer companies, including Curium, Merck, Telix Pharmaceuticals, Exelixis, AstraZeneca, AB Science, Lantheus, Pfizer, Jiangsu Hengrui Pharmaceuticals, Modra Pharmaceuticals, Bristol-Myers Squibb, MacroGenics, Syntrix Pharmaceuticals, Zenith Epigenetics, Xencor, Bristol Myers Squibb, Merus, Phosplatin Therapeutics, Laekna Therapeutics, Tavanta Therapeutics, Madison Vaccines, Taiho Pharmaceutical, Kangpu Biopharmaceuticals, Arvinas, Candel Therapeutics, Blue Earth Therapeutics, Ipsen Biopharmaceuticals, LAVA Therapeutics, Essa Pharma, Poseida Therapeutics, Janux Therapeutics, Aurigene Oncology, Sathgen Therapeutics, Full-Life Technologies, NextPoint Therapeutics, AbbVie, SL VAXiGEN, Sorrento Therapeutics, Inc., 858 Therapeutics, Avacta Life Sciences Ltd, Nammi Therapeutics, BeiGene, DualityBio, among others. Endometriosis Market Endometriosis Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key endometriosis companies, including Mitsubishi Tanabe Pharma America, Ferring Pharmaceuticals, AbbVie, Neurocrine Biosciences, ObsEva, Kissei Pharmaceuticals, SWK, Enteris BioPharma, Bayer, Hope Medicine, Organon, among others. Uterine Fibroids Market Uterine Fibroids Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key uterine fibroids companies, including AbbVie Inc., Addex Therapeutics Ltd, Bayer AG, BioSpecifics Technologies Corp, Dongkook Pharmaceutical Co Ltd, Kissei Pharmaceutical Co Ltd, Myovant Sciences, Ogeda SA, Repros Therapeutics Inc., Takeda Pharmaceutical Company Ltd, among others. About DelveInsight DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve. Contact UsShruti Thakur info@ +14699457679 Logo: View original content:
Malaysian Reserve
10 hours ago
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Elevating Clinical Excellence: TLCx Appoints Dr Ries as Chief Medical Officer
CEDAR RAPIDS, Iowa, Aug. 13, 2025 /PRNewswire/ — TLCx is taking a significant step toward its long-term vision of transforming the healthcare patient experience. This move underscores the company's dedication to pioneering a new era of healthcare, one rooted in thoughtful design, patient-centered systems, and clinically sound innovation. 'This is more than just a clinical appointment; it signifies a key milestone in realizing TLCx's Vision 2030,' said Dr. Zachary Ries, Chief Medical Officer. 'It will pioneer a new era of healthcare patient experience driven by intelligent design, human-first systems, and clinically grounded innovation.' TLCx is pleased to welcome Dr. Zachary Ries as its first Chief Medical Officer. This decisive appointment highlights TLCx's dedication to reshaping the patient experience through clinically grounded innovation and human-first systems. Dr. Ries's expertise will be instrumental in guiding TLCx toward its Vision 2030, which focuses on creating a healthcare journey prioritizing the needs and well-being of patients. Tom Cardella, Founder and CEO of TLCx, added, 'I've known Dr. Ries for many years, and I couldn't be more excited to have him join TLCx, especially at this time of transformation through human-driven AI solutions. His expertise and vision will be pivotal as we redefine healthcare delivery.' Dr. Zachary Ries is a Board-Certified Orthopedic Spine Surgeon from Des Moines, Iowa, with nearly 18 years of medical experience. A University of Iowa graduate with advanced fellowship training at Norton Leatherman Spine Center, he is dedicated to improving patient care through clinical expertise and innovation. The addition of a Chief Medical Officer will benefit the company in the following ways: Enhanced Clinical Leadership: Dr. Ries will provide vital leadership, ensuring TLCx's strategies and innovations are firmly rooted in medical expertise. Patient-Centered Approach: With Dr. Ries at the helm, TLCx will further emphasize a patient-centered approach, designing systems and experiences that address the unique needs of each individual. Realization of Vision 2030: This appointment marks a milestone in realizing TLCx's Vision 2030, moving the company closer to its goal of transforming healthcare patient experience. Drive Innovation: Dr. Ries will also help drive innovation at TLCx, leading development of products, services, and solutions that improve patient experience and outcomes. About TLCx:TLCx is a certified veteran-owned company dedicated to enhancing customer experiences for Fortune 500 companies through innovative outsourcing solutions. With a focus on operational excellence and a people-first culture, TLCx has been a trusted partner in the CX industry for 18 years. For more information, visit Media Contact:Bryan GrayChief Commercial
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DeepSight™ Technology Receives First FDA 510(k) Clearance for NeedleVue™ LC1 Ultrasound System
Bringing Clarity and Confidence to Ultrasound-Guided Interventional Procedures SANTA CLARA, Calif., Aug. 13, 2025 /PRNewswire/ — DeepSight Technology, a medical imaging pioneer, announced that it has received U.S. Food and Drug Administration (FDA) 510(k) clearance for its NeedleVue™ LC1 Ultrasound System. This clearance marks an important step forward in DeepSight's development of its NeedleVue™ and OnPoint™ technologies that will work in tandem with the NeedleVue™ LC1 Ultrasound System to transform image-guided procedures. 'This is a foundational milestone in our mission to deliver crystal clear, sub millimeter level guidance inside the body,' said Nader Sadrzadeh CEO of DeepSight. 'We have developed the next generation sensor technology for enhancing ultrasound where it what matters most—clear visualization, procedural efficiency, and user confidence. We're just getting started and look forward to building on this achievement as we expand our clinical and commercial momentum in the months ahead.' To learn more about the NeedleVue™ LC1 Ultrasound System and DeepSight's mission to advance procedural ultrasound, visit Visit DeepSight at the upcoming LSI'25 Europe meeting in London September 7th – 11th and Cardiovascular and Interventional Radiological Society of Europe (CIRSE) conference in Barcelona, September 13–17, to experience NeedleVue technology firsthand. About DeepSight TechnologyDeepSight Technology, founded in 2019 by Nader Sadrzadeh, Lan Yang, and Anand Chandrasekher, is built on a bold vision — to revolutionize medical imaging through proprietary sensing technology. With offices in the San Francisco Bay Area and Clayton, Missouri, DeepSight aims to extend the capabilities of ultrasound across diagnostic, therapeutic, surgical, and interventional applications —advancing patient care and improving public health worldwide. Our next-generation sensor technology will transform ultrasound, with the goal to deliver exceptional clarity, pinpoint precision, and unparalleled confidence for clinicians in every procedure.
