Alzheimer's disease: A blood test can detect early symptoms, finds study
Researchers at the Mayo Clinic in the U.S. have been working on a new blood test that can accurately detect early signs of Alzheimer's disease, and the results are seriously impressive. This test looks at two specific proteins in your blood—amyloid beta 42/40 and p-tau217—both of which are linked to that gunky buildup in the brain called amyloid plaques, a telltale sign of Alzheimer's.
So how accurate is it? Try 95% sensitivity, meaning it correctly identifies people who do have memory problems 95% of the time.
That's pretty hard to beat. It also has 82% specificity, which means it's also really good at ruling out people who don't have Alzheimer's.
What's even better? This isn't just lab testing. The study was done on over 500 real patients in a memory clinic—so it's based on actual, day-to-day medical situations, not just controlled experiments.
Dr. Gregg Day, who led the study (published in Alzheimer's & Dementia journal), said this new blood test works just as well as the more invasive and expensive options we currently use.
"It's about as accurate as spinal fluid testing," he told The Guardian, 'but way easier, less painful, and much cheaper.'
In people who had Alzheimer's, the levels of p-tau217 were clearly higher compared to those who didn't, which helped the team confirm the diagnosis confidently.
The best part? This blood test has already gotten the green light from the U.S. FDA—so it's not just theory anymore, it's actually available.
6 million Americans are living with Alzheimer's disease
Alzheimer's disease is becoming a huge concern across the U.S.—and it's not just about forgetfulness in old age. It's a progressive brain disorder that slowly chips away at memory, thinking skills, and the ability to do everyday tasks. Right now, more than 6 million Americans are living with Alzheimer's, and that number is expected to nearly double by 2050.
Most people with Alzheimer's are 65 or older, but it can also hit younger adults in what's called early-onset Alzheimer's.
The biggest risk factor is age, but family history and genetics also play a role. The disease usually starts slow—maybe forgetting names or getting lost in familiar places—and worsens over time.
The best part is science is catching up. New blood tests and brain imaging tools are helping doctors catch the disease earlier than ever before. There are also a few new medications out that might slow down the progression if taken early enough.
Next up, researchers want to test it on even more diverse groups of people and also those who might be in the very early stages of Alzheimer's but don't have any symptoms yet.
In short: diagnosing Alzheimer's just got a whole lot simpler—and that could change everything when it comes to early intervention and treatment.
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