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CAPITAL INSURANCE GROUP RECOGNIZED IN 2025 AMERICAN BUSINESS AWARDS®

CAPITAL INSURANCE GROUP RECOGNIZED IN 2025 AMERICAN BUSINESS AWARDS®

Yahoo21-05-2025

CIG takes home Gold and Silver Stevie® Awards
MONTEREY, Calif., May 21, 2025 /PRNewswire/ -- Capital Insurance Group® (CIG®), a leading regional property and casualty insurer in the Western U.S., is proud to announce multiple teams within the company have been selected as honorees in separate categories for the 23rd Annual American Business Awards ®.
Capital Insurance Group was awarded a Gold Stevie® Award in the Company of the Year - Insurance – Large category. Additionally, two teams were recognized as Teams of the Year with the Development Team taking home a Gold Stevie® Award for Technology Team of the Year, and the Communications Team receiving a Silver Stevie® Award. Judges had high praise for CIG, remarking on their resilience, ability to expand products, continued attainment of financial metrics, and noted the company successfully attracted and retained customers amid tough regulatory challenges. CIG was recognized for its customer-focused approach which yields high retention and glowing customer testimonials.
CIG's IT Development team was recognized for their innovation, resilience, and impact on the company through major system upgrades, cloud migrations, and enhanced quoting tools. The result of their cross-functional collaboration and efforts was improved agent transparency, operational efficiency, and improved customer experience.
Judges celebrated CIG's Communications team for their strategic approach, measurable results, and impressive nature of accomplishments, especially given their size. Also noteworthy was the team's ability to overcome challenges, demonstrating agility, creativity, and operational excellence with demonstrable strategic impact.
At Capital Insurance Group, a strong commitment to open and transparent communication shapes the company's culture and drives success. Guided by CIG's core values that serve as the foundation of its operations, the CIG team works collaboratively to deliver results and do what's right. The company embraces a thoughtful, measured approach to decision-making, reflected in the guiding principle "measure twice; cut once," a reminder shared across CIG to prioritize integrity and excellence in everything they do.
CIG President & CEO, Andy Doll reflected on the awards: "Everyone at CIG has been working hard for a long time, and those efforts have been reflected in our results. These awards illustrate how this hard work is being recognized by those independent from the company. This adds greater credibility and value of every CIG employee's effort."
The Stevie® Awards, established in 2002, honor organizations and professionals globally for their achievements. The American Business Awards® accept nominations from all U.S. organizations across various categories. This year, over 3,600 nominations were submitted by organizations of all sizes, judged by more than 250 professionals worldwide to determine the winners. More details and the 2025 Stevie winners list can be found at www.StevieAwards.com/ABA.
About Capital Insurance Group
Established in 1898, Capital Insurance Group® (CIG®) is a leading regional property and casualty insurer in the Western U.S. CIG offers trusted Agriculture, Commercial, and Personal coverage across Arizona, California, Nevada, Oregon, and Washington.
Known for superior customer service and customizable coverage, CIG delivers insurance solutions tailored to meet the needs of policyholders, sold exclusively through independent agents. CIG's suite of insurance offerings include coverage for Homeowners, Renters, Personal Auto, Dwelling Fire, Businessowners, Commercial Auto, Farm Owners, Commercial Agriculture, Farm Auto, Commercial Real Estate, and more. Throughout its footprint, CIG partners with regional and local charitable organizations and events to give back to communities in ways that promote preparedness, enhance resilience, and bring relief to communities in crisis.
CIG is underwritten by its affiliate companies: California Capital Insurance Company, Eagle West Insurance Company, Nevada Capital Insurance Company, and Monterey Insurance Company. CIG is rated "A" (Excellent) by AM Best, the independent financial monitor of the insurance industry and is proud to be part of the Auto-Owners Insurance group of companies, one of the nation's largest, most-trusted insurers. For more information, please visit CIGInsurance.com.
View original content to download multimedia:https://www.prnewswire.com/news-releases/capital-insurance-group-recognized-in-2025-american-business-awards-302462187.html
SOURCE Capital Insurance Group

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The British Medical Journal Publishes Study Results on Sacituzumab Tirumotecan for Previously Treated EGFR-Mutant Advanced NSCLC
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CHENGDU, China, June 6, 2025 /PRNewswire/ -- Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. ("Kelun-Biotech", today announced that results from its registrational study (OptiTROP-Lung03) evaluating sacituzumab tirumotecan (sac-TMT) versus docetaxel in patients with previously treated advanced EGFR-mutant non-small cell lung cancer (NSCLC) have been published in The British Medical Journal (impact factor: 93.6). These data were also presented as an oral presentation in the Lung Cancer—Non–Small Cell Metastatic session (Abstract #8507) at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting. Based on the encouraging data from this study, sac-TMT was approved for marketing by the National Medical Products Administration (NMPA) for the treatment of adult patients with epidermal growth factor receptor (EGFR) mutant-positive locally advanced or metastatic non-squamous NSCLC following progression on EGFR-tyrosine kinase inhibitor (TKI) therapy and platinum-based chemotherapy in March 2025. This marks the first global approval of a TROP2 ADC for a lung cancer indication. The published results are based on OptiTROP-Lung03, an open-label, randomized, multicenter registrational study evaluating the efficacy and safety profile of sac-TMT monotherapy versus docetaxel for the treatment of patients with locally advanced or metastatic EGFR-mutant NSCLC who have failed after treatment with an EGFR-TKI and platinum-based chemotherapy. A total of 137 patients with advanced EGFR-mutant NSCLC who had progressed after EGFR-TKI and platinum-based chemotherapy were randomized (2:1) to receive sac-TMT (5 mg/kg once every 2 weeks) or docetaxel (75 mg/m2 once every 3 weeks) until disease progression, intolerable toxicity or other reason for discontinuation, with a median follow-up time of 12.2 months (Data cutoff date: December 31, 2024). Sac-TMT achieved statistically significant and clinically meaningful outcomes compared to docetaxel: Confirmed objective response rate (ORR) (As assessed by blinded independent review committee (BIRC): 45% (95% CI, 35-56) vs 16% (95% CI, 7-30). Median progression-free survival (PFS) (As assessed by BIRC: 6.9 months [sac-TMT; 95% CI, 5.4-8.2] vs 2.8 months [docetaxel; 95% CI, 1.6-4.1], hazard ratio (HR)= 0.30 [range, 0.20 -0.46], one-sided p<0.0001; as assessed by investigator (INV): 7.9 months [sac-TMT; 95% CI, 6.2-9.5] vs 2.8 months [docetaxel; 95% CI, 1.5-3.8], HR=0.23 [95% CI, 0.15-0.36], one-sided p<0.0001). With 36.4% of patients in docetaxel group crossing over to receive sac-TMT, median overall survival (OS) was not reached (NR) for both groups (HR=0.49; 95% CI, 0.27-0.88; one-sided p=0.007). The median OS analysed by pre-specified rank-preserving structural failure time (RPSFT) model adjusted for crossover was 9.3 months for docetaxel and NR for sac-TMT (HR=0.36; 95% CI, 0.20-0.66). 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Meanwhile, Merck Sharp & Dohme(the tradename of Merck & Co., Inc., Rahway, NJ, USA)is also conducting five global Phase III clinical trials of sac-TMT for NSCLC in regions where it has exclusive rights. Professor Li Zhang, National Lead Principal Investigator, Medical Oncologist and Deputy Director of the Lung Cancer Research Centre at Sun Yat-Sen University, stated: "EGFR mutation is the most common driver alteration in NSCLC. The prevalence of EGFR mutations reaches 28.2% among NSCLC patients in China. Although third-generation EGFR-TKIs have become the standard of care for advanced EGFR-mutant NSCLC and may significantly improve PFS, acquired resistance remains inevitable. Combining EGFR-TKIs with chemotherapy can offer additional survival benefits to some patients, but this approach is limited by safety concerns and may compromise future treatment options, posing significant clinical challenges. The publication of the OptiTROP-Lung03 study in the British Medical Journal marks a major milestone—not only highlighting international recognition of this study outcomes in lung cancer, but also demonstrating the global competitiveness of sac-TMT as a novel TROP2 ADC." Dr. Michael Ge, CEO of Kelun-Biotech, commented: "We are thrilled to see the OptiTROP-Lung03 study published in a top-tier journal. Currently, EGFR-TKIs and chemotherapy remain the standard of care for patients with EGFR-mutant advanced NSCLC, but the challenge of increasing efficacy with manageable tolerability. The results from OptiTROP-Lung03 highlight significant survival benefits with manageable safety profile and suggest that sac-TMT could emerge as a new standard of care for this population. We remain committed to working with our partners to establish sac-TMT as a new standard of care for this patient population and improve outcomes for lung cancer patients worldwide." Registrational Study Led by Kelun-Biotech OptiTROP-Lung03: Sac-TMT monotherapy versus docetaxel for locally advanced or metastatic EGFR-mutant NSCLC after treatment failure with EGFR-TKI and platinum-containing chemotherapy; OptiTROP-Lung04: Sac-TMT monotherapy versus pemetrexed in combination with platinum for locally advanced or metastatic non-squamous NSCLC with EGFR mutations that have failed EGFR-TKI therapy; OptiTROP-Lung05: Sac-TMT combined with pembrolizumab versus chemotherapy combined with pembrolizumab for first-line treatment of PD-L1-positive locally advanced or metastatic NSCLC; OptiTROP-Lung06: Sac-TMT combined with pembrolizumab versus chemotherapy combined with pembrolizumab for the first-line treatment of PD-L1-negative locally advanced or metastatic non-squamous NSCLC; OptiTROP-Lung07: First-line treatment of locally advanced or metastatic NSCLC with EGFR mutations by sac-TMT in combination with ositinib. Registrational Study Led by MSD NSCLC not achieving a pCR after neoadjuvant therapy followed by surgery. NSCLC expressing PD-L1 >50% pre-treated NSCLC with EGFR mutations or other genomic alterations EGFR-mutated, advanced non-squ NSCLC progressed on prior EGFR-TK metastatic sg NSCLC About sac-TMT Sac-TMT, a core product of the Company, is a novel human TROP2 ADC in which the Company has proprietary intellectual property rights, targeting advanced solid tumors such as NSCLC, BC, gastric cancer (GC), gynecological tumors, among others. Sac-TMT is developed with a novel linker to conjugate the payload, a belotecan-derivative topoisomerase I inhibitor with a drug-to-antibody-ratio (DAR) of 7.4. Sac-TMT specifically recognizes TROP2 on the surface of tumor cells by recombinant anti-TROP2 humanized monoclonal antibodies, which is then endocytosed by tumor cells and releases KL610023 intracellularly. 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