
This $469 anti-aging serum is now just $99 in Perricone MD's huge Memorial Day sale - and shoppers say it 'erases 20 YEARS'
Aging is unavoidable, and over time, it shows — fine lines, age spots, wrinkles, and sagging can have you sprinting to the nearest med spa. The good news? With Perricone MD, you can get advanced treatments right at home.
The legendary skincare brand is offering exceptional deals in its Memorial Day sale through June 1, 2025, with 25 percent off your entire purchase (no minimum). Spend over $100 and it's bumped to 30 percent off, with savings increasing to 40 percent when you spend $100. Just enter code MDS25 at checkout to take advantage.
Perricone MD Cold Plasma Plus+ Advanced Serum Concentrate
Upgrade your skincare routine with this bestselling serum formulated to target multiple signs of aging.
Supercharged with vitamin C ester, omega oils, and copper peptides, it's a wrinkle-smoothing powerhouse that has a stunning effect on lines.
In fact, a whopping 100 percent of users saw fewer wrinkles within 28 days of use. This an exceptional deal for the largest 6-ounce bottle.
$99 (was $469) Shop
The brand has dozens of exceptional formulas, including the groundbreaking Cold Plasma Plus+ Advanced Serum Concentrate. This is truly the star of the show, with a 6-ounce bottle retailing for $469 now reduced to just $99.
For a jaw-dropping discount of 79 percent, the product goes deep to target even the most stubborn wrinkles — those deep-set ones that would otherwise only respond to the needle — and give your complexion a big, youthful boost.
Not only does it handle lines, but the fragrance-free serum is also formulated to minimize pores, brighten, reduce imperfections (like spots and redness), and firm skin while improving overall tone and texture.
Clinical results are truly impressive, with a stunning 100 percent of users reporting an improvement in the appearance of fine lines and wrinkles over the course of 28 days. And 97 percent felt their pores were reduced, too.
It's down to a cocktail of skin-loving ingredients that work harmoniously to treat, nurture, and support skin. Among those is vitamin C ester, a potent antioxidant that revitalizes to leave skin looking more radiant and feeling smoother.
Pro-fatty acids derived from omegas 3, 6, and 9 pack a punch, plumping your complexion while locking in moisture so your skin feels softer than ever. With copper peptide added to firm up your skin and promote a more youthful look, the serum is the anti-aging formula of your dreams.
It's no wonder that the reviews are absolutely stellar, with one user writing, 'I've used this product for several years. All I can tell you is I'm 67 and my friends tell me I look like I am in my late 40s!'.
Another said, 'I am in love with this serum! Just a tiny bit is necessary and my skin just drinks it in. I've had so many compliments from people asking me what I'm doing and why I don't have any wrinkles!'
It's worth the small investment for the big payoff — your skin will absolutely thank you for adding this to your routine, especially if your primary concern is reducing the visible signs of aging. Don't miss it and other Perricone MD deals this Memorial Day.
Perricone MD Vitamin C Ester Brightening Amine Face Lift
Could your complexion use a brightening boost? Vitamin C is your go-to, and this fast-absorbing serum is the perfect antidote.
Designed to slough away dead skin cells while improving tone, it's an anti-aging superhero that works over time to diminish the appearance of fine lines and wrinkles.
It's extremely lightweight, too, and sinks in on contact for a clean, non-sticky, non-greasy feel.
Up to 40% off Shop
Perricone MD High Potency Hyaluronic Intensive Hydrating Serum
Even the driest skin is no match for this deeply hydrating serum. It contains four different types of hyaluronic acid, known for trapping moisture to keep skin plump and soft.
With DMAE to firm and lift, this serum could be the secret to your skin's success!
It has both a moisturizing and anti-aging effect, reducing dullness to reveal a brighter and healthier appearance that feels as great as it looks.
Up to 40% off Shop
Perricone MD No Makeup Foundation Serum
Hate the feel of heavy, cakey foundation? This liquid serum is the answer. It feels incredible, with a gorgeous, lightweight consistency that you can build for greater coverage.
Not only does it cover imperfects, but it's formulated to actually reduce them over time.
That's thanks to ingredients like daisy flower extract, which can have a gentle diminishing effect on discoloration, and neuropeptides to firm and minimize sagging.
Up to 40% off Shop
Perricone MD No Makeup Mascara
Natural lashes without the gunky finish? Yes, please! This is one of Perricone MD's most beloved products.
It instantly lifts and thickens to reveal a gorgeous, full, plump lash that looks shockingly real.
It's both a conditioner and a mascara, with nourishing biotin and hydrating avocado oil added to give your lashes a lustrous look while promoting thickness. The result? The lashes of your dreams!
Up to 40% off Shop
Perricone MD Essential Fx Acyl-Glutathione Eyelid Lift Serum
The eye area is one of the first to reveal your age, as the skin is delicate and thin.
This 'eyelift in a bottle' could be your secret weapon, as it's formulated to smooth away unsightly creases and sagging that affects the lids.
It's really a multipurpose product, as it also improves elasticity and reduces discoloration, all while eliminating dark circles and crepey texture. It's super light and absorbs quickly, too.
Up to 40% off Shop
Perricone MD Essential Fx Acyl-Glutathione Deep Crease Serum
Sometimes the deepest facial lines need a little extra TLC. To the rescue comes this highly potent formula that targets the lines most vulnerable — think marionettes, nasolabial folds, and lip lines.
This works like a charm, going deep to fill out those hollows created by repetitive facial movements.
Used regularly, the product boosts your skin's moisture barrier while protecting from damaging free radicals.
Up to 40% off Shop

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