logo
ME Therapeutics Receives Support to Advance mRNA Therapeutic Candidates for Cancer and Inflammatory Disease

ME Therapeutics Receives Support to Advance mRNA Therapeutic Candidates for Cancer and Inflammatory Disease

National Post21-05-2025

Article content
VANCOUVER, British Columbia — ME Therapeutics Holdings Inc. ('ME Therapeutics' or the 'Company') (CSE: METX) (FSE: Q9T), a publicly listed preclinical biotechnology company working on novel cancer fighting drugs in the field of immuno-oncology, today announced that its subsidiary, ME Therapeutics Inc., is receiving advisory services and up to $140,000 in funding from the National Research Council of Canada Industrial Research Assistance Program (NRC IRAP). The project will support the research and development of ME Therapeutic's mRNA therapeutic program targeting myeloid cell biology for the treatment of cancer and inflammatory disease.
Article content
Article content
'We are pleased to receive this support from NRC IRAP, which builds on advisory services and funding received in past years, to allow us to further advance preclinical studies for our mRNA therapeutic candidates that target key myeloid cell pathways,' said Salim Dhanji, CEO of ME Therapeutics. 'Our team at ME Therapeutics passionately believes myeloid cell-derived mRNA therapies represent the next wave of treatments for patients with cancer and inflammatory disease who today have limited treatment options, and we are committed to bringing these potential new approaches to the clinic as soon as possible.'
Article content
ME Therapeutics's proprietary mRNA sequences have been engineered to encode for proteins that can modify the immune response in vivo in a targeted manner. Their lead mRNA therapeutic candidate is specifically designed to modulate immune cells in the tumour microenvironment and stimulate an anti-cancer immune response. Preclinical testing has already demonstrated encouraging anti-cancer activity in a mouse model of colorectal cancer. In addition, ME Therapeutics is exploring design modifications of its mRNA candidates to modulate mRNA expression in a tissue-specific manner for increased efficacy and safety.
Article content
About ME Therapeutics
Article content
Myeloid Enhancement (ME) Therapeutics is a publicly listed, preclinical stage biotechnology company based in Vancouver involved in the discovery and development of novel immuno-oncology therapeutics targeting immune suppression in cancer. Our focus is on overcoming the suppressive effects of an important class of immune cells called myeloid cells to enhance anti-cancer immunity. For more information, visit metherapeutics.com.
Article content
Neither the Canadian Securities Exchange nor any Market Regulator (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release.
Article content
This news release includes certain 'forward-looking statements' under applicable Canadian securities legislation. Forward-looking statements consist of statements that are not purely historical, including any statements regarding beliefs, plans, expectations or intentions regarding the future. Such forward-looking statements in this news release include, but are not limited to, statements regarding the Company's collaborations, research plans, the timing for completion of studies and the receipt of results, the intended outcomes of the research, the intended benefits and applications of the Company's technology, and the Company's plans for development of its business. Such statements are subject to risks and uncertainties that may cause actual results, performance or developments to differ materially from those contained in the statements, including risks related to factors beyond the control of the Company, that the results of the testing are not favorable, that future research does not support continued development, that regulatory approvals are not obtained or maintained, that challenges related to mRNA technology development, including delivery, stability, or efficacy issues cannot be overcome, that the Company relies on third-party collaborators and vendors for certain aspects of the research, that the research will not be completed within the expected timeline, that the Company is unable to obtain intellectual property protection for the results, that the Company may require additional funding to advance its research and develop its business, and that the Company's business may not develop as set out in this news release. No assurance can be given that any of the events anticipated by the forward-looking statements will occur or, if they do occur, what benefits the Company will obtain from them. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ from forward-looking statements. The Company disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.
Article content
Article content
Article content
Article content
Contacts
Article content
Article content
Article content

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Third day of searching for four missing in Quebec medical helicopter crash
Third day of searching for four missing in Quebec medical helicopter crash

CTV News

time29 minutes ago

  • CTV News

Third day of searching for four missing in Quebec medical helicopter crash

Police are spending a third day searching for four people who went missing after a medical transport helicopter crashed on Quebec's North Shore. The Airmedic helicopter crashed into a lake late Friday near Natashquan, Que., just over 1,000 kilometres northeast of Montreal. Five people were aboard the aircraft when it went down. One person escaped, and Airmedic said their life is not in danger. Quebec provincial police are investigating the crash along with the Transportation Safety Board of Canada and Quebec's workplace health and safety board. Airmedic said Sunday that it was suspending operations to offer support to its employees. This report by The Canadian Press was first published June 23, 2025.

In the rush to build more homes, Embrun flood sparks questions about oversight
In the rush to build more homes, Embrun flood sparks questions about oversight

CTV News

time30 minutes ago

  • CTV News

In the rush to build more homes, Embrun flood sparks questions about oversight

In the rush to build homes faster amid Canada's housing crisis, an Ottawa-based contractor is raising serious questions about oversight and whether crucial steps are being skipped after a devastating flood in Embrun, Ont. 'They say let's build more houses but let's be very careful what conditional approvals we give or what steps we skip because if we skip the wrong step, this can happen,' said contractor Ryan Branton, host of The Contractor Ryan show. 'What happened here? This house went up quick and now we're seeing the consequences of it.' Embrun Ontario Contractor Ryan Branton looks at an Embrun property that was destroyed by March flooding. (Katelyn Wilson/ CTV News). In March, a catastrophic flood gutted two newly built semi-detached homes, leaving homeowners with hundreds of thousands of dollars worth of damage and seven tenants without homes. 'The human aspect is not here,' said tenant and homeowner Arlene Woods. 'I was supposed to be preparing myself for retirement, the next stage of life and this was the investment that we were working with. I'm close to my grandkids, I have a beautiful view, and it was all stripped away.' Embrun Homeowners are seeking accountability after learning about grading issues on their property after taking ownership. (Andrew Greaves/ Provided) Long before the flood, Branton says the warning signs were there as he surveyed the damage, comparing the original plans with what was built. 'The plans kind of tell the story because this was supposed to be 18 inches and it's like seven, so it's a little red flag,' Branton said while measuring the height of the porch. He says the discrepancy between the original plans and the finished build, coupled with the absence of a final grading certificate in municipal files, raises serious questions about oversight. 'When that permit closes, everything needs to be in the hands of the municipality, your grading, all your building inspections,' said Branton. He says the final grading certificate, which confirms that a property slopes away from the home to prevent flooding, is supposed to be on file before final inspection. While the Township of Russell signed off on the property in late 2024, that certificate is missing from municipal records. So too is a final grading plan and engineering report for a retaining wall installed in August 2024 by the builder, Saca Homes. 'They put in the retaining wall to try to solve those retaining issues, but did they engineer that? Did they call someone in to look at it? My eye tells me they didn't,' said Branton. 'It's a red flag. Something was skipped, there was oversight. What that was, I'm not 100 per cent sure, but these grading reports or these final inspections typically come as a package.' An engineering report obtained by CTV News Ottawa concludes that improper grading and a blocked catch basin caused the flood, but the homeowners say they weren't told about any deficiencies until after they moved in. Embrun Homeowners are seeking accountability after learning about grading issues on their property in Embrun, Ont. after taking ownership. (Andrew Greaves/ Provided) Emails from the builder show work was still being signed off on after the homeowners took possession. 'I feel like there should have been more issues or more red flags and we should have at least been made aware that this could have been a possibility at the end of the day,' said homeowner Josée Greaves. Both the builder Saca Homes and the township are pointing fingers at the developer, a numbered company, 1437137 Ontario Inc. In an email to CTV News, Robert Bourdeau says he is not the developer but confirmed he's a director and officer of the company behind the project. He is also the founder of Robert Excavating, which was called in to help with flood mitigation. 'It's not just the builder who's involved here, there's the developer, the person who developed the land long before the property was sold,' said Branton. 'Certainly, the township here has got some responsibility to bear too, they were here they approved the plans,' said Branton. While the water may be gone, the damage remains. 'It's very frustrating and if you don't feel you're responsible, go after whoever is,' said homeowner Brenden Haldane. 'It shouldn't be our responsibility to go after whoever is responsible, we bought the house from the builder.' Greaves says insurance is covering some of the damage to her home, while Haldane says he's been left high and dry by his insurance company. The homeowners have filed claims with Tarion, Ontario's new home warranty program, and are currently waiting for the results of the investigation.

The Beer Store closing Manotick outlet this summer
The Beer Store closing Manotick outlet this summer

CTV News

time36 minutes ago

  • CTV News

The Beer Store closing Manotick outlet this summer

The Beer Store says its location on Carling Avenue, across the street from Carlingwood Mall, will close on June 15. (Andrew Adlington/CTV News Ottawa) The Beer Store location in Manotick is closing in August, the fourth store to close in Ottawa this year. The Beer Store announced 10 stores will close across Ontario on August 24, including the store on Beaverwood Road in Manotick. 'Closing a retail store is never an easy decision - our stores and employees contribute to communities in many ways and provide easy access to empty returns throughout Ontario,' Ozzie Ahmed, vice president of Retail at the Beer Store, said in a statement. 'We are modernizing operations and focusing on what we do best, selling ice cold beer, great customer service and a world leading recycling system that gets customers their deposit money back.' The Beer Store on Bank Street near Holmwood Avenue will close on July 20. The Beer Store on Carling Avenue, across from the Carlingwood Mall, closed on June 15. The retailer closed the Beer Store on North Side Road in Bells Corners in February. The decision to close Beer Store outlets comes after Ontario expanded beer and alcohol sales to big box stores, corner stores and gas stations last year. The United Food and Commercial Workers Union told CTV News Ottawa earlier this year that the Beer Store is allowed to go down to 300 stores by the end of this year under an early implementation agreement. The Beer Store has locations on Terry Fox Drive, Ogilvie Road, Fallowfield Road, 1680 Bank Street, Baseline Road, Montreal Road, and Somerset Street West.

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into a world of global content with local flavor? Download Daily8 app today from your preferred app store and start exploring.
app-storeplay-store