Sanofi's $9.5B acquisition of Blueprint Medicines strengthens rare immunology portfolio
In a major move underscoring its ambition to lead in rare diseases and immunology, French pharmaceutical giant Sanofi announced its plan to acquire US-based Blueprint Medicines for up to $9.5 billion.
The deal was announced by a press release on Sanofi's website. It is the largest by a European healthcare company this year and will see Sanofi paying $129 per share in cash, a significant premium that sent Blueprint's stock soaring in premarket trading.
Blueprint Medicines, known for its specialty in treating systemic mastocytosis a rare blood disorder marked by the overproduction of mast cells brings to Sanofi a strong foothold in a niche yet critical area of medicine.
The acquisition adds the FDA-approved drug Ayvakit, the only treatment for advanced systemic mastocytosis, to Sanofi's growing immunology portfolio.
Sanofi CEO Paul Hudson framed the deal as a strategic leap forward, enhancing the company's pipeline and reinforcing its transformation into a global leader in immunology.
We announced an agreement to acquire Blueprint Medicines, a biopharmaceutical company specializing in systemic mastocytosis, a rare immunological disease, and other KIT-driven diseases. — Sanofi (@sanofi) June 2, 2025
With a promising pipeline including next-generation therapies like elenestinib and BLU-808, the acquisition fits into Sanofi's broader ambition of innovation despite recent setbacks, including a failed lung disease drug trial.
Industry analysts from JP Morgan praised the acquisition for its strategic and financial merits, forecasting Ayvakit could generate $2 billion in annual sales by 2030.
Sanofi's ongoing spree of acquisitions, including Vigil Neuroscience and Inhibrx, signals a company doubling down on R&D investments to reshape its future.
The acquisition aligns with Sanofi's broader strategy to invest heavily in US manufacturing and research, tapping into incentives and momentum driven by recent government policies.
With Blueprint Medicines now joining its portfolio, Sanofi cements its stake in cutting-edge immunology treatments and rare disease therapies, positioning itself for long-term growth in a competitive pharmaceutical landscape.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Business Recorder
an hour ago
- Business Recorder
US-backed Gaza aid group to halt distribution on Wednesday, UN to vote on ceasefire demand
CAIRO/OCCUPIED JERUSALEM/UNITED NATIONS: The US-backed Gaza Humanitarian Foundation will not give out any aid on Wednesday as it presses Israel to boost civilian safety beyond the perimeter of its distribution sites, a day after dozens of Palestinians seeking aid were killed. The GHF said it has asked the Israeli military to 'guide foot traffic in a way that minimizes confusion or escalation risks' near military perimeters; develop clearer guidance for civilians; and enhance training to support civilian safety. 'Our top priority remains ensuring the safety and dignity of civilians receiving aid,' said a GHF spokesperson. An Israeli military spokesperson warned civilians against moving in areas leading to GHF sites on Wednesday, deeming them 'combat zones'. The Israeli military said on Tuesday that it opened fire on a group of people it viewed as a threat near a GHF food aid distribution site. The International Committee of the Red Cross said at least 27 people were killed and dozens injured. The GHF said the incident was 'well beyond' its site. Rescuers say Israeli fire kills at least 27 near Gaza aid point Palestinians who collected food GHF boxes on Tuesday described scenes of pandemonium, with no-one overseeing the handover of supplies or checking IDs, as crowds jostled for aid. The U.N. Security Council is also set to vote on Wednesday on a demand for a ceasefire between Israel and Palestinian militants Hamas and humanitarian access across Gaza, where aid has trickled amid chaos and bloodshed after Israel lifted an 11-week blockade on the enclave where famine looms. 'It is unacceptable. Civilians are risking – and in several instances losing – their lives just trying to get food,' UN spokesperson Stephane Dujarric said on Tuesday, adding that the aid distribution model backed by the U.S. and Israel was 'all a recipe for disaster, which is exactly what is going on.' That model is run by the newly created GHF, which started operations in the enclave a week ago and said on Tuesday that it has given out more than seven million meals from three so-called secure distribution sites. GHF Interim Executive Director John Acree urged humanitarians in Gaza: 'Work with us and we will get your aid delivered to those who are depending on it.' US Veto? The U.N. and other aid groups have refused to work with the GHF because they say it is not neutral and the distribution model militarizes aid. GHF uses private U.S. security and logistics companies to get aid to the distribution sites. It is the latest in a string of efforts to get more aid into the enclave, where experts say the entire population of some 2.1 million people is at risk of famine. Jordan last year spearheaded humanitarian air drops, while the U.S. briefly installed a floating aid pier, but it was beset by challenges. The U.N. has long-blamed Israel and lawlessness in the enclave for hindering the delivery of aid into Gaza and its distribution throughout the war zone. Israel accuses Hamas of stealing aid, which the group denies. Israel said on Tuesday that three of its soldiers had been killed in fighting in northern Gaza. Gaza health officials said at least 18 more Palestinians were killed in other military strikes in the territory on Tuesday. Reuters could not independently verify the reports in northern and southern Gaza. The 10 elected members of the U.N. Security Council have asked for the 15-member body to vote on Wednesday on a draft resolution that demands 'an immediate, unconditional and permanent ceasefire in Gaza respected by all parties.' The draft text, seen by Reuters, also demands the release of all hostages held by Hamas and others, and the immediate lifting of all restrictions on the entry of aid and its safe and unhindered distribution, including by the U.N., throughout Gaza. 'The time to act has already passed,' Slovenia's U.N. Ambassador Samuel Zbogar told Reuters. 'It is our historical responsibility not to remain silent.' Hamas says ready to 'immediately' hold round of Gaza truce talks As U.S. President Donald Trump's administration tries to broker a ceasefire in Gaza, it was not immediately clear if Washington would veto the draft text. A spokesperson for the U.S. mission to the U.N. said: 'We cannot preview our actions currently under consideration.' A resolution needs nine votes in favor and no vetoes by the permanent members - the United States, Russia, China, Britain or France - to pass. The war in Gaza has raged since 2023 after Hamas killed 1,200 people in Israel in an October 7 attack and took some 250 hostages back to the enclave, according to Israeli tallies. Israel responded with a military campaign that has killed over 54,000 Palestinians, according to Gaza health authorities, which do not distinguish between fighters and non-combatants.
Express Tribune
an hour ago
- Express Tribune
Rivals Meloni and Macron seek to mend fences
Italy's Giorgia Meloni and France's Emmanuel Macron met Tuesday in Rome, seeking to reconcile their differences as they confront common challenges, notably US tariffs and the Ukraine war. The far-right prime minister welcomed the centrist French president to her Palazzo Chigi office, the pair kissing lightly on the cheek and both smiling. A guard of honour played both national anthems before the two European rivals headed inside for talks and a dinner, with no plans to speak to the press. They are not natural political allies, but as the leaders of the EU's second- and third-largest economies, they are both grappling with the fall-out from the war in Ukraine, as well as US President Donald Trump's sweeping tariffs against the bloc. Meloni on Friday acknowledged "divergences" with Macron but denied she had any "personal problems" with him, and said she was "very happy" with the visit. An Italian government source said Rome and Paris hoped to "lay the foundations for a further strengthening of relations" between two nations "on the front line of the various fronts of international politics".
Business Recorder
an hour ago
- Business Recorder
South Korea's new president Lee Jae-myung vows economic revival, judgment on martial law
SEOUL: South Korea's new liberal President Lee Jae-myung began his term on Wednesday, vowing to raise the country from the turmoil of a martial law crisis and revive an economy reeling from slowing growth and the threat of global protectionism. Lee's decisive victory in Tuesday's snap election stands to usher in a sea change in Asia's fourth-largest economy, after backlash against a botched attempt at military rule brought down Yoon Suk Yeol just three years into his troubled presidency. He faces what could be the most daunting set of challenges for a South Korean leader in nearly three decades, ranging from healing a country deeply scarred by the martial law attempt to tackling unpredictable protectionist moves by the United States, a major trading partner and a security ally. With 100% of the ballots counted, Lee won 49.42% of the nearly 35 million votes cast while conservative rival Kim Moon-soo took 41.15% in the polls that brought the highest turnout for a presidential election since 1997, according to National Election Commission data. The 61-year-old former human rights lawyer called Tuesday's election 'judgment day' against Yoon's martial law and his People Power Party's failure to stop the ill-fated move. 'The first mission is to decisively overcome insurrection and to ensure there will never be another military coup with guns and swords turned against the people,' Lee said in a victory speech outside parliament. 'We can overcome this temporary difficulty with the combined strength of our people, who have great capabilities,' he said. Lee was officially confirmed as president by the National Election Commission on Wednesday and immediately assumed the powers of the presidency and commander in chief. An abbreviated inauguration is planned at parliament at 11 a.m. (0200 GMT), an Interior Ministry official said. Lee has said he would address urgent economic challenges facing the country on the first day in office with a focus on the cost-of-living concerns affecting middle and low-income families and the struggles of small business owners. He also faces a deadline set by the White House on negotiating import duties that Washington has blamed for a large trade imbalance between the countries. 'Deal with Trump' The government under a caretaker acting president had made little progress in trying to assuage crushing tariffs announced by U.S. President Donald Trump's administration that would hit some of the country's major industries, including autos and steel. South Korea's presidential election set to reshape policies for key U.S. ally 'President Lee will find himself with little to no time to spare before tackling the most important task of his early presidency: reaching a deal with Trump,' the Washington-based Center for Strategic and International Studies said in an analysis. U.S. Secretary of State Marco Rubio congratulated Lee on his election win and said the countries 'share an ironclad commitment to the Alliance grounded in our Mutual Defense Treaty, shared values, and deep economic ties.' He also said that the countries were 'modernising the Alliance to meet the demands of today's strategic environment and address new economic challenges.' The White House said the election of Lee was 'free and fair' but the United States remained concerned and opposed to Chinese interference and influence in democracies around the world, according to a White House official. Lee has expressed more conciliatory plans for ties with China and North Korea, in particular singling out the importance of China as a major trading partner while indicating reluctance to take a firm stance on security tensions in the Taiwan strait. Still, Lee has pledged to continue Yoon's engagement with Japan and said the alliance with the United States is the backbone of South Korea's global diplomacy. The martial law decree and the six months of ensuing turmoil, which saw three different acting presidents and multiple criminal insurrection trials for Yoon and several top officials, marked a stunning political self-destruction for the former leader and a drag on an economy already slowing growth.
