logo
Biking might help lower risk of dementia

Biking might help lower risk of dementia

Miami Heralda day ago

Want to reduce your risk of dementia and Alzheimer's disease?
Get on your bike and ride, a new study recommends.
Biking regularly for transportation appears to lower risk of dementia by 19% and Alzheimer's by 22%, according to results published Tuesday in JAMA Network Open.
The results also suggest that cycling might even help increase the size of a brain region important for memory, researchers noted.
"Cycling is a moderate- to high-intensity workout, and also requires balance," said Dr. Liron Sinvani, director of geriatric services at Northwell Health in Manhasset, N.Y., who reviewed the findings. "It requires more complex brain function than walking, which is why maybe it was a better reducer of dementia risk."
"It's not about just doing exercise and making that part of your routine, but thinking about the way you live your life," she added in a news release. "So instead of having to drive somewhere, taking that bike and using active travel modes to get around as part of your lifestyle becomes very important."
For the study, researchers analyzed data on nearly 480,000 people participating in the UK Biobank, a long-term health study of people living in England, Scotland and Wales.
As part of the study, participants noted the forms of transport they used most often to get about, not including travel to and from work.
During an average follow-up of 13 years, more than 8,800 participants developed dementia and nearly 4,000 developed Alzheimer's.
Results showed a lower risk for dementia and Alzheimer's among those who cycled or included cycling among other forms of travel like walking, driving or using public transportation.
"Our findings suggest that promoting active travel strategies, particularly cycling, may be associated with lower dementia risk among middle-aged and older adults, which carries substantial public health benefits by encouraging accessible, sustainable practices for cognitive health preservation," concluded the research team led by Liangkai Chen, an associate professor at Tongji Medical College at the Huazhong University of Science and Technology in Wuhan, China.
MRI brain scans showed that cycling also was associated with a larger hippocampus, a part of the brain involved in memory formation and learning, researchers noted.
However, cycling's benefits appeared to extend mostly to people without a genetic risk for Alzheimer's, results showed.
People without the APOE E4 genetic variant had a 26% lower risk of dementia and 25% lower risk of Alzheimer's.
Results were not statistically significant among APOE E4 carriers, but indicated less protection from cycling.
Interestingly, the results also indicate that driving offered some protection against dementia compared to taking the bus or subway.
"Even when using inactive travel like car or public transportation, it seemed like driving had a little bit better impact [on brain health] than public transportation," Sinvani said in the news release.
However, researchers noted that this observational study could not draw a direct cause-and-effect link between cycling and healthy brain aging.
"What I tell my patients and family and friends whenever they ask me what they can do to reduce their risk of dementia, is whatever gets you outside doing stuff is what you should be doing," she said. "I think we see that it's not just the physical activity, but it's also in the balance, and it really engages different parts of your brain."
If you're able to get on a bike, Sinvani said, do that. If you're aren't, use your feet.
"I think if it's, 'should I walk or take a bike?' I would say take a bike, but if it's 'should I walk or just stay home?' I would say definitely walk," she said.
More information
The U.S. Centers for Disease Control and Prevention has more on how physical activity boosts brain health.
Copyright © 2025 HealthDay. All rights reserved.
Copyright 2025 UPI News Corporation. All Rights Reserved.

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Analysis of the European Hospitals Market 2025-2030: Investment Opportunities for Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Sweden, Belgium, and Ireland
Analysis of the European Hospitals Market 2025-2030: Investment Opportunities for Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Sweden, Belgium, and Ireland

Yahoo

time2 hours ago

  • Yahoo

Analysis of the European Hospitals Market 2025-2030: Investment Opportunities for Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Sweden, Belgium, and Ireland

The market is poised for growth, driven by aging demographics, technological advances, and a shift to value-based care. Key opportunities lie in digital health, infrastructure upgrades, and workforce development. Addressing workforce shortages and integrating value-based models will be crucial for sustainability. European Hospital Market Dublin, June 13, 2025 (GLOBE NEWSWIRE) -- The "Europe Hospital Market, By Country, Competition, Forecast and Opportunities, 2020-2030F" has been added to offering. The Europe Hospital Market was valued at USD 0.85 Trillion in 2024, and is expected to reach USD 1.09 Trillion by 2030, rising at a CAGR of 4.35%. This mature and advanced market is anchored by strong public healthcare systems, cutting-edge infrastructure, and a widespread commitment to universal care access. The sector's growth is being fueled by shifting demographics, especially aging populations, along with rapid technological progress and evolving patient expectations. To maintain performance and meet rising demand, hospitals are undergoing digital transformation, expanding service capacity, and focusing on operational modernization. Investments in digital health, workforce development, and facility upgrades are becoming critical. Meanwhile, the shift toward integrated, value-based care models is redefining hospital operations and emphasizing efficiency, outcome measurement, and long-term sustainability, ensuring hospitals remain central to Europe's healthcare landscape. Key Market Driver Aging Population and Chronic Disease Burden Europe's aging population and the resulting increase in chronic diseases are major factors propelling the hospital market. By 2030, the number of Europeans living with Alzheimer's and related dementias is expected to rise to 14 million, escalating the healthcare system's financial and operational demands. The projected economic impact of Alzheimer's care is set to exceed USD 721.37 billion by 2050. As per Eurostat, individuals aged 65 and older made up 21.1% of the EU's population in 2022, and this is forecasted to rise to 32.5% by 2100. Older populations are more prone to conditions such as cardiovascular disease, diabetes, osteoporosis, neurodegenerative disorders, and cancer, all of which increase hospital care needs. Consequently, hospitals are expanding geriatric and chronic care services, modernizing infrastructure, and adapting clinical operations to manage growing patient loads. Key Market Challenge Workforce Shortages and Talent Retention The shortage of skilled medical professionals - including nurses, general practitioners, and specialists - poses a significant challenge for hospitals across Europe. Contributing factors include an aging healthcare workforce, burnout, and early retirements, particularly in under-resourced public systems. Staffing shortages reduce care quality, extend wait times, and hinder hospitals' ability to scale operations or adopt innovative models. The increased use of temporary staffing and overtime also inflates labor costs. Addressing this challenge requires strategic investment in training programs, international recruitment, and adoption of automation technologies such as AI-driven diagnostics and robotic procedures to ease clinical burdens and improve workforce efficiency. Key Market Trend Integration of Value-Based Healthcare Models European hospitals are transitioning from fee-for-service to value-based healthcare (VBHC) models, which emphasize care quality, patient outcomes, and cost-effectiveness. Government mandates and payer incentives are accelerating this shift to improve healthcare delivery and financial sustainability. Hospitals are redesigning care pathways around bundled, patient-centered services with a focus on chronic disease management, preventative care, and post-discharge support. The implementation of performance-based KPIs is reshaping reimbursement models, promoting efficiency, and reducing readmissions. Advanced analytics and predictive tools are increasingly used to track outcomes, manage resources, and demonstrate value - ultimately strengthening hospitals' competitiveness and long-term viability in the evolving European health ecosystem. Key Market Players Profiled: HCA Healthcare UK Fresenius SE & Co. KGaA Spire Healthcare Group plc Orpea Group Asklepios Klinik Barmbek Sana Kliniken AG San Donato Group (Gruppo San Donato) Report Scope In this report, the Europe Hospital Market has been segmented into the following categories: Europe Hospital Market, By Product: Public Private Europe Hospital Market, By Type: General Specialty Multi-Speciality Europe Hospital Market, By Type of Services: In-Patient Services Out-Patient Services Europe Hospital Market, By Bed Capacity: Up to 100 beds 100-500 beds Above 500 beds Europe Hospital Market, By Country: Germany France United Kingdom Italy Spain Netherlands Switzerland Sweden Belgium Ireland Key Attributes Report Attribute Details No. of Pages 125 Forecast Period 2024-2030 Estimated Market Value (USD) in 2024 $0.85 Trillion Forecasted Market Value (USD) by 2030 $1.09 Trillion Compound Annual Growth Rate 4.3% Regions Covered Europe For more information about this report visit About is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. Attachment European Hospital Market CONTACT: CONTACT: Laura Wood,Senior Press Manager press@ For E.S.T Office Hours Call 1-917-300-0470 For U.S./ CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Analysis of the European Hospitals Market 2025-2030: Investment Opportunities for Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Sweden, Belgium, and Ireland
Analysis of the European Hospitals Market 2025-2030: Investment Opportunities for Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Sweden, Belgium, and Ireland

Yahoo

time2 hours ago

  • Yahoo

Analysis of the European Hospitals Market 2025-2030: Investment Opportunities for Germany, France, UK, Italy, Spain, Netherlands, Switzerland, Sweden, Belgium, and Ireland

The market is poised for growth, driven by aging demographics, technological advances, and a shift to value-based care. Key opportunities lie in digital health, infrastructure upgrades, and workforce development. Addressing workforce shortages and integrating value-based models will be crucial for sustainability. European Hospital Market Dublin, June 13, 2025 (GLOBE NEWSWIRE) -- The "Europe Hospital Market, By Country, Competition, Forecast and Opportunities, 2020-2030F" has been added to offering. The Europe Hospital Market was valued at USD 0.85 Trillion in 2024, and is expected to reach USD 1.09 Trillion by 2030, rising at a CAGR of 4.35%. This mature and advanced market is anchored by strong public healthcare systems, cutting-edge infrastructure, and a widespread commitment to universal care access. The sector's growth is being fueled by shifting demographics, especially aging populations, along with rapid technological progress and evolving patient expectations. To maintain performance and meet rising demand, hospitals are undergoing digital transformation, expanding service capacity, and focusing on operational modernization. Investments in digital health, workforce development, and facility upgrades are becoming critical. Meanwhile, the shift toward integrated, value-based care models is redefining hospital operations and emphasizing efficiency, outcome measurement, and long-term sustainability, ensuring hospitals remain central to Europe's healthcare landscape. Key Market Driver Aging Population and Chronic Disease Burden Europe's aging population and the resulting increase in chronic diseases are major factors propelling the hospital market. By 2030, the number of Europeans living with Alzheimer's and related dementias is expected to rise to 14 million, escalating the healthcare system's financial and operational demands. The projected economic impact of Alzheimer's care is set to exceed USD 721.37 billion by 2050. As per Eurostat, individuals aged 65 and older made up 21.1% of the EU's population in 2022, and this is forecasted to rise to 32.5% by 2100. Older populations are more prone to conditions such as cardiovascular disease, diabetes, osteoporosis, neurodegenerative disorders, and cancer, all of which increase hospital care needs. Consequently, hospitals are expanding geriatric and chronic care services, modernizing infrastructure, and adapting clinical operations to manage growing patient loads. Key Market Challenge Workforce Shortages and Talent Retention The shortage of skilled medical professionals - including nurses, general practitioners, and specialists - poses a significant challenge for hospitals across Europe. Contributing factors include an aging healthcare workforce, burnout, and early retirements, particularly in under-resourced public systems. Staffing shortages reduce care quality, extend wait times, and hinder hospitals' ability to scale operations or adopt innovative models. The increased use of temporary staffing and overtime also inflates labor costs. Addressing this challenge requires strategic investment in training programs, international recruitment, and adoption of automation technologies such as AI-driven diagnostics and robotic procedures to ease clinical burdens and improve workforce efficiency. Key Market Trend Integration of Value-Based Healthcare Models European hospitals are transitioning from fee-for-service to value-based healthcare (VBHC) models, which emphasize care quality, patient outcomes, and cost-effectiveness. Government mandates and payer incentives are accelerating this shift to improve healthcare delivery and financial sustainability. Hospitals are redesigning care pathways around bundled, patient-centered services with a focus on chronic disease management, preventative care, and post-discharge support. The implementation of performance-based KPIs is reshaping reimbursement models, promoting efficiency, and reducing readmissions. Advanced analytics and predictive tools are increasingly used to track outcomes, manage resources, and demonstrate value - ultimately strengthening hospitals' competitiveness and long-term viability in the evolving European health ecosystem. Key Market Players Profiled: HCA Healthcare UK Fresenius SE & Co. KGaA Spire Healthcare Group plc Orpea Group Asklepios Klinik Barmbek Sana Kliniken AG San Donato Group (Gruppo San Donato) Report Scope In this report, the Europe Hospital Market has been segmented into the following categories: Europe Hospital Market, By Product: Public Private Europe Hospital Market, By Type: General Specialty Multi-Speciality Europe Hospital Market, By Type of Services: In-Patient Services Out-Patient Services Europe Hospital Market, By Bed Capacity: Up to 100 beds 100-500 beds Above 500 beds Europe Hospital Market, By Country: Germany France United Kingdom Italy Spain Netherlands Switzerland Sweden Belgium Ireland Key Attributes Report Attribute Details No. of Pages 125 Forecast Period 2024-2030 Estimated Market Value (USD) in 2024 $0.85 Trillion Forecasted Market Value (USD) by 2030 $1.09 Trillion Compound Annual Growth Rate 4.3% Regions Covered Europe For more information about this report visit About is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. Attachment European Hospital Market CONTACT: CONTACT: Laura Wood,Senior Press Manager press@ For E.S.T Office Hours Call 1-917-300-0470 For U.S./ CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Scientists Map How Alzheimer's Begins in the Brain
Scientists Map How Alzheimer's Begins in the Brain

Newsweek

time2 hours ago

  • Newsweek

Scientists Map How Alzheimer's Begins in the Brain

Based on facts, either observed and verified firsthand by the reporter, or reported and verified from knowledgeable sources. Newsweek AI is in beta. Translations may contain inaccuracies—please refer to the original content. In an unprecedented large-scale study, researchers have mapped out the first molecular events that cause harmful protein buildups in the brain of people with Alzheimer's disease. "By measuring the effects of over 140,000 different versions of proteins, we have created the first comprehensive map of how individual mutations alter the energy landscape of amyloid beta aggregation—a process central to the development of Alzheimer's disease," said paper author and computational biologist Anna Arutyunyan of the Wellcome Sanger Institute in a statement. "Our data-driven model offers the first high-resolution view of the reaction's transition state, opening the door to more targeted strategies for therapeutic intervention," Arutyunyan added. The Alzheimer's Association estimates that some 7.2 million Americans aged 65 and older are presently living with the disease. Its first outward symptom is typically memory problems, but it can lead to delusions, speech issues, disturbed sleep and mood swings. Artist's impression of amyloid-beta peptide buildups within the brain. Artist's impression of amyloid-beta peptide buildups within the brain. selvanegra/iStock / Getty Images Plus At the heart of more than 50 different neurodegenerative diseases is the molecule amyloid beta. This peptide (a chain of amino acids) has a tendency to clump together, forming structures known as amyloid fibrils. In turn, these fibrils gather together into so-called "plaques"—which play a central role in the progression of Alzheimer's disease. The transition from free-flowing amyloid beta to stable fibril structures requires a certain amount of energy—with the peptides having to pass through a "transition state." This state is extremely unlikely to form, accounting for why fibrils and plaques never form in most people. It is also extremely short-lived, which helps account for how difficult it is to study how amyloid beta starts aggregating. Nevertheless, understanding these molecular structures and reactions will be vital for the future development of therapies against Alzheimer's and similar conditions. In the new study, Arutyunyan and colleagues probed the amyloid beta transition by exploring how changing the genetics of the peptide affects its aggregation rate. The team focused on Aβ42, a form of the amyloid beta with 42 amino acids that is commonly found in people with Alzheimer's disease. The researchers used three techniques in their work. First, "massively parallel sequencing" allowed the team to see how changing the amino acids in Aβ42 affects the amount of energy needed to form a fibril. Next, they used genetically engineered yeast cells to measure the rate of the aggregation reaction. Finally, the team used machine learning tools to analyze the results and map out the effect of all the possible mutations of the peptide on fibril formation. In total, the team were able to assess more than 140,000 versions of Aβ42 in one pop—a breakthrough in scale that boosts the accuracy of the resulting models. Read more Map shows states where risk of dementia is highest—are you living in one? Map shows states where risk of dementia is highest—are you living in one? The analysis revealed that only a very few specific interactions between parts of the amyloid beta peptide strongly influenced the rate of fibril formation. Furthermore, the team found that the aggregation reaction begins at one of the tightly packed, water-repellent ends of the peptide, which is known as the C-terminal region. Accordingly, the researchers hope that targeting interactions in this region might allow new means to protect against and treat Alzheimer's disease. "The approach we used in this study opens the door to revealing the structures of other protein transition states, including those implicated in other neurodegenerative diseases," said genomicist professor Ben Lehner, also of the Wellcome Sanger Institute, in a statement. "The scale at which we analyzed the amyloid peptides was unprecedented … we have shown it's a powerful new method to take forward. "We hope this takes us one step closer to developing treatments against Alzheimer's disease and other neurodegenerative conditions," Lehner added. Do you have a tip on a health story that Newsweek should be covering? Do you have a question about Alzheimer's disease? Let us know via health@ Reference Arutyunyan, A., Seuma, M., Faure, A. J., Bolognesi, B., & Lehner, B. (2025). Massively parallel genetic perturbation suggests the energetic structure of an amyloid-β transition state. Science Advances, 11 (24).

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into the world of global news and events? Download our app today from your preferred app store and start exploring.
app-storeplay-store