Northwell Health Opens Center for Bioelectronic Medicine

Business Wire

13-05-2025

NEW HYDE PARK, N.Y.--(BUSINESS WIRE)--After decades of pioneering bioelectronic medicine research, Northwell Health today announced the opening of its clinical Center for Bioelectronic Medicine. Those interested in participating in bioelectronic medicine clinical trials, including studies evaluating vagus nerve stimulation, can do so through the new Center. As bioelectronic medicine devices are approved for use, they will be offered to patients at the Center.
The first Center is located at 350 Community Drive in Manhasset, NY. The facility features a waiting area, patient rooms and a clinical space for research nurses, doctors and clinical trial coordinators to consult with patients and participants. Northwell intends to relocate and expand the Manhasset location within the next few years. Planning is underway for a second center located in Manhattan, NY.
'Northwell Health prides itself on offering patients innovative treatment. Bioelectronic medicine has shown benefit to patients in clinical trials, and with the development and expansion of the field, we have an opportunity to offer this cutting-edge treatment to our patients,' said Michael J. Dowling, president and CEO of Northwell. 'Northwell's Center for Bioelectronic Medicine is a unique destination where doctors, scientists and patients will explore and potentially benefit from today's medical advancements.'
The scientific foundation of bioelectronic medicine stems from research conducted by Kevin J. Tracey, MD, president and CEO of The Feinstein Institutes for Medical Research, Northwell's home of medical research, and author of the new book The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes – available today. For nearly four decades, Dr. Tracey and collaborators published their discoveries about a link between the brain, immune system, and inflammation and whether or not their connection could be modulated through technology and electrical signals, like vagus nerve stimulation. Today, bioelectronic medicine clinical trials are conducted at Northwell and around the world. In 2023, Northwell was a site for the SetPoint Medical RESET-RA study, which evaluated a novel treatment option for rheumatoid arthritis (RA) using neuroimmune modulation, a therapy that uses electrical stimulation to modulate functions of the immune system.
Dawn Steiner, one of the RESET-RA trial participants, has firsthand experience with the debilitating effects of RA. For more than a decade, the 58-year-old speech and language pathologist from Massapequa, NY, felt excruciating pain that often left her bedridden. An avid Mets fan and concertgoer, Dawn found herself unable to enjoy the things she loved – or even conduct everyday tasks, like brushing her teeth or tying her shoes – because of her RA flare-ups or her medication's side effects. Over the years, she tried more than eight biological RA medications that often didn't relieve her symptoms and made her feel troubling side effects. After seeing family and friends benefit from enrolling in clinical trials for other conditions, Dawn enrolled in the SetPoint Medical trial and today many of her symptoms are relieved.
'A year after receiving this therapy, I feel as good as I did before my RA diagnosis – like a different person. I feel better, and I'm able to just feel healthy and do all the things that make me happy without those awful, awful medications,' Steiner said. 'To the researchers, thank you! I'm so glad you looked into a different type of technology. From my perspective, this is the future of rheumatoid arthritis treatment.'
The new Center will aim to connect participants like Dawn to bioelectronic medicine clinical trials. Current bioelectronic medicine trials underway at Northwell include treatments for pediatric inflammatory bowel disease, methods to stop excessive bleeding, treatments for post-traumatic stress disorders and brain implant applications to reverse paralysis.
'There is optimism that bioelectronic medicine could replace some drugs that have serious side effects and associated costs, and I am interested in continuing research in this field to better understand the language of the nervous system and see if we can use that knowledge to help the body heal itself,' said Dr. Tracey, Karches Family Distinguished Chair in Medical Research at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. 'Clinical trial participants are my heroes – their courage and commitment send ripples of change throughout medicine, bringing us closer to a future where we can treat diseases in safer, more effective, and personalized ways.'
At the Feinstein Institutes, medical researchers use modern technology to develop novel device-based therapies to treat disease and injury. Engineers, computer scientists, immunologists, neuroscientists, and clinicians develop cutting-edge medicine, including neuroimmune modulation, miniature implants for stimulating and recording the vagus nerve, noninvasive ultrasound neuromodulation to suppress inflammation, and novel brain-computer interfaces to overcome injuries of the nervous system.
In the early 2000s, Dr. Tracey and his colleagues discovered that the brain regulates the production of inflammatory proteins, a key aspect of the body's immune response. This brain-body-immune connection was termed the 'inflammatory reflex.' Despite the revelation more than two decades ago, a recent national survey conducted by Ipsos on behalf of the Feinstein Institutes suggests that many Americans are unaware of this connection between the brain and the body. According to the survey, nearly two-thirds of Americans (64%) don't believe or don't know that the brain controls inflammation. Uncontrolled inflammation can contribute to diseases like RA, Crohn's disease, and inflammatory bowel disease. Dr. Tracey's research led to the founding of SetPoint Medical in 2007; where he currently serves as an advisor. Dr. Tracey's book, The Great Nerve, explores the groundbreaking discovery of how stimulating the vagus nerve can treat chronic illnesses and improve overall health, offering both scientific explanations and real-life patient stories.
For more information about bioelectronic medicine, click here. If you are interested in learning more about the center and current bioelectronic clinical trials offered at Northwell Health, click here or call 1-227-BIO-INST (246-4678).
For download able photos and videos of Dawn, Dr. Tracey, the Center for Bioelectronic Medicine and others, click here.
About Northwell Health
Northwell is the largest not-for-profit health system in the Northeast, serving residents of New York and Connecticut with 28 hospitals, more than 1,000 outpatient facilities, 22,000 nurses and over 20,000 physicians. Northwell cares for more than three million people annually in the New York metro area, including Long Island, the Hudson Valley, western Connecticut and beyond, thanks to philanthropic support from our communities. Northwell is New York State's largest private employer with over 104,000 employees – including members of Northwell Health Physician Partners and Nuance Health Medical Practices – who are working to change health care for the better. Northwell is making breakthroughs in medicine at the Feinstein Institutes for Medical Research. Northwell is training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, X, Instagram and LinkedIn.
About the Feinstein Institutes:
The Feinstein Institutes for Medical Research is the home of the research institutes of Northwell Health, the largest health care provider and private employer in New York State. Encompassing 50+ research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its six institutes of behavioral science, bioelectronic medicine, cancer, health system science, molecular medicine, and translational research. We are the global scientific leader in bioelectronic medicine – an innovative field of science that has the potential to revolutionize medicine. The Feinstein Institutes publishes two open-access, international peer-reviewed journals Molecular Medicine and Bioelectronic Medicine. Through the Elmezzi Graduate School of Molecular Medicine, we offer an accelerated PhD program. For more information about how we produce knowledge to cure disease, visit http://feinstein.northwell.edu and follow us on LinkedIn.