ASCO 2025: Impact of Therapeutic Advances in Prostate Cancer
Petros Grivas, MD, shares key updates from ASCO 2025, focusing on advances in prostate cancer across disease stages. He highlights promising results from the AMPLITUDE trial showing a radiographic progression-free survival benefit with niraparib plus abiraterone in patients with BRCA-mutated tumors and anticipated further data from the PSMAddition trial involving lutetium-PSMA.
Additional discussions included prostate-specific antigen nadir as a prognostic marker, quality-of-life outcomes from the ARANOTE trial, and emerging therapies like BiTEs and theranostics for castration-resistant disease. He emphasizes the importance of somatic and germline testing in personalizing treatment and improving outcomes for both patients and their families.
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