Astros at Marlins Prediction: Odds, expert picks, starting pitchers, betting trends and stats for August 6
Spencer Arrighetti (thumb) is slated to take the mound for Houston for the first time since a start April 5 against the Twins while Miami sends Janson Junk to the mound to start the game.
Houston made it two straight wins over Miami with a 7-3 win Tuesday night. Jose Altuve homered for the 19th time this season and for the 248th time in his career to pace the attack and five pitchers combined to limit the Marlins to five hits.
Lets dive into this afternoon's matchup and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Astros at Marlins
Date: Wednesday, August 6, 2025
Time: 4:40PM EST
Site: LoanDepot Park
City: Miami, FL
Network/Streaming: SCHN, FDSNFL
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Astros at the Marlins
The latest odds as of Wednesday:
Moneyline: Astros (-110), Marlins (-110)
Spread: Marlins 1.5
Total: 8.0 runs
Probable starting pitchers for Astros at Marlins
Pitching matchup for August 6, 2025: Spencer Arrighetti vs. Janson Junk
Astros: Spencer Arrighetti (1-1, 5.59 ERA)Last outing: April 5 at Minnesota - 12.27 ERA, 5 Earned Runs Allowed, 3 Hits Allowed, 3 Walks, and 3 Strikeouts
Marlins: Janson Junk (5-2, 3.86 ERA)Last outing: August 1 vs. Yankees - 10.80 ERA, 6 Earned Runs Allowed, 6 Hits Allowed, 1 Walks, and 4 Strikeouts
Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!
Top betting trends & insights to know ahead of Astros at Marlins
The Astros are on a 4-game win streak in Miami
7 of the Marlins' last 9 games with the Astros have gone over the Total
The Marlins have failed to cover in their last 4 games against the Astros
Janson Junk has failed to reach the sixth inning in any of his last 3 starts
Christian Walker has 1 hit in his last 3 games and is 4-19 (.211) through 5 games in August
If you're looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for today's game between the Astros and the Marlins
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Wednesday's game between the Astros and the Marlins:
Moneyline: NBC Sports Bet is recommending a play on the Houston Astros on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Miami Marlins at +1.5.
Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
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Xavier Edwards singled. So did Kyle Stowers. And Liam Hicks. And Otto Lopez. And Jakob Marsee. And Heriberto Hernández. Six of the first seven Marlins batters singled off Astros starter Spencer Arrighetti in the first inning Wednesday, giving the Marlins more hits and as many runs (three) as they had in all of Tuesday's loss — and they were just getting started. They added a run in the second and third innings, and eventually held on to beat the Astros 7-6 at loanDepot park, avoiding a sweep before heading out on an 11-game road trip against the Braves, Guardians, and Red Sox. Trailing 2-0 early Wednesday, the Marlins were up for the challenge. 'It continues to speak to their resiliency, their ability to respond,' Marlins manager Clayton McCullough said. 'And to go down as we did, [starter] Janson [Junk] then really buckled down and gave us five solid innings. And offensively, we were certainly much better in the early going today in this game than in the previous couple of days. 'Really good job working at-bats. A lot of traffic on the bases and moving the ball around to a lot of places on the field. To score some runs and punch back there was good. Now you're back in the fight. We were showing the resiliency this group has shown on a number of occasions. So, a really good sign again for our guys to come back and win this game, finish off the homestand with a winning record [4-2] before we head to a tough stretch of [five] games in four days there coming up in Atlanta.' Edwards was the ultimate table setter for the Marlins on Wednesday, as the leadoff man went 4-for-5 with two runs scored. Rookies Hernández and Graham Pauley both homered — Hernández went deep to 391 feet to left center in the third and Pauley drilled a pitch 394 feet to right center in the fifth. And reliever Calvin Faucher made the defensive play of the day to help himself escape a jam in the eighth inning. With one out, he charged Cam Smith's grounder near the third-base line, backhanded it with his glove, leapt into the air, and fired an off-balance strike to catcher Agustín Ramírez, who tagged out Walker sliding into home. 'Calvin tells us all the time how phenomenal of an athlete he is,' McCullough said. 'And he got to put that on display tonight.' Junk, meanwhile, allowed three runs on five hits with two strikeouts and two walks in five innings He allowed back-to-back doubles to Mauricio Dubón and Carlos Correa in the fifth inning. And in the first inning, Christian Walker hammered a fastball 417 feet to left center off him, bringing home former Marlin Jesús Sánchez after his double. The Marlins quickly erased that 2-0 deficit, though, with Hicks, Lopez, and Hernández each collecting an RBI. 'Absolutely, it was really good offense for the team in that inning,' Hernández said via team interpreter Luis Dorante Jr. 'He was throwing a lot of fastballs. So, we pretty much made him go to secondary pitches. It's a pretty good feeling when you start hitting like that. … With the record of the series after we lost the first two, we were really looking forward to winning this game after that.' Left-hander Ryan Weathers, on the 60-day injured list with a left lat strain, threw a bullpen session Wednesday. 'It was exciting to watch. Ryan looked great. He's in a really good place right now, mentally, physically,' said McCullough, adding Weathers would travel with the team to Atlanta. 'We're very excited with how this has come along considering where things were a few months ago.' McCullough said the team is 'cautiously optimistic' Weathers will return to pitch sometime this season. 'Not to try to put it out there that it's going to happen,' he noted. 'We're just excited it's even a possibility at this point And we'll just let how Ryan continues to feel and responds to increase in intensity and volume guide where that ends up taking us.' The Marlins' projected starters for the Braves series are Eury Pérez (Thursday), Edward Cabrera (Friday), Sandy Alcantara (Saturday, Game 2), and Cal Quantrill (Sunday). The Game 1 starter for Saturday's doubleheader is still to be determined.
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