
To know them is to loath them: Oak Park's Alec Nevala-Lee finds a niche, writing about science's biggest jerks
Nevala-Lee's previous biography was on Buckminster Fuller, architect, futurist, longtime professor at Southern Illinois University, but also an infamously obtuse, inscrutable mansplainer's mansplainer — his lectures seemed to go on for days. Before that, Nevala-Lee wrote 'Astounding,' a harrowing account of the men behind mid-century science fiction, particularly editor John W. Campbell, who could be described charitably as fascist.
His next book, already in the works, is about those lovable scamps behind the RAND Corporation, the most despised think tank in history. Am I nuts or do I see a pattern here?
'No question!' Nevala-Lee said the other day, getting a little loud in his neighborhood library. 'I like intelligent people who succeed in one field only to try and apply those skills elsewhere and decide that they should convince the world that only they have the answer to certain problems.'
At the risk of playing pop psychologist, I asked a natural follow-up:
Is that you, too?
'I mean, uh… I it.' He smiled. 'Am I a reasonably intelligent person who thought a lot about where to apply their skills? Sure.' I asked this because he attended Harvard University and left with a degree in classics and an over-confident idea that knowing the classics was really the only way to become a writer. So when his fiction-writing career stalled before it could get started, he decided to reinvent himself. He developed a talent for writing quite accessible histories of the boorish.
The boorish, but brilliant.
As Nevala-Lee explains in 'Collisions: A Physicist's Journey From Hiroshima to the Death of the Dinosaurs,' his surprisingly breezy new history of Luis Alvarez, the Nobel laureate and occasional Chicagoan was pragmatic, for better and for worse. He preferred to work where his skills would get noticed by the widest number of important people — smartly leading to funding and fame. Alvarez had, Nevala-Lee writes, taste when it came to science. Meaning, eventually, after years of frustration in Hyde Park, he knew how to pick projects that 'were both achievable and important.'
Which is an understatement.
Alvarez learned how to position himself at the heart of the 20th century.
He helped develop radar during World War II. He worked on the creation of the atomic bomb with Enrico Fermi and J. Robert Oppenheimer. He flew behind the Enola Gay as a scientific observer while it dropped the first nuclear weapon on Japan. In fact, Alvarez's bubble chamber, the project that would earn him a Nobel, may have been his least publicized work: a pressurized chamber to help scientists study particle behavior. It was groundbreaking, though not as thrilling as proving — using a bunch of watermelons and a high-powered rifle — why the Warren Commission was probably correct about the assassination of President John F. Kennedy. In Alvarez's last decades, as if knocking out a little extra credit, he even gave us the answer to a mystery we all know the answer to now: He explained how a planet ruled by dinosaurs could go extinct nearly overnight.
But … he was also something of a bootlicker.
'Alvarez knew how to cleave to power,' Nevala-Lee said. 'In a way I find interesting. The contrast to Oppenheimer is real, because Oppenheimer, equally brilliant, spoke his truth as he saw it.'
He came to regret his role in creating nuclear weapons, so at the peak of McCarthy-era paranoia, his loyalty to the government was doubted and the head of the Manhattan Project's Los Alamos Laboratory had his security clearance revoked.
Alvarez, meanwhile, 'was very careful about alienating people he needed to get stuff done,' Nevala-Lee said. 'In fact, and this is important, he doubled down and felt the solution to the Soviet problem was definitely a thermonuclear bomb. Alvarez would even become one of those people who was all for mutual assured destruction. Oppenheimer was not. Alvarez had such a high opinion of his own intelligence that when he sees someone equally bright, like Oppenheimer, opposing him on a fundamental point, he assumed it couldn't be he's wrong — no, Oppenheimer must be compromised. I don't know if he really believed that for sure, but I think so: Alvarez saw it to his advantage if Oppenheimer could be neutralized. He was causing problems, and Alvarez's work would go smoother if he was out of the way.'
In the end, ever an opportunist, Alvarez testified Oppenheimer was loyal to his country, yet wrong on nukes. Not the profile in courage that makes for Oscar biopics. (Indeed, in Christopher Nolan's 'Oppenheimer,' Alvarez is mostly on hand to say Germans just split the atom. Then he's gone from the picture. Alvarez, whose career was just getting started in 1939, wouldn't have been pleased.)
To make matters worse, egads — Alvarez didn't seem to be a big fan of Chicago.
Scientist Luis Walter Alvarez with a radio transmitter used in a radar ground-controlled approach system built to help guide airplanes to land. (AP)
His ex-wife lived here with his ex-mother-in-law. During the development of the bomb, while traveling constantly between MIT and Los Alamos, he would call Chicago his 'decompression chamber,' but after working for a while at Argonne National Laboratory in Lemont, he felt rudderless and assumed all of the interesting science was being done elsewhere. He became something of a legend around Hyde Park — 'high on my list of mythological figures,' is how one scientist at University of Chicago described him — but Alvarez himself complained bitterly of his undergraduate education at the school, a place where, he said: 'Most of the graduate students didn't understand any quantum mechanics, largely for the reason that the professors had just learned it themselves.'
He sounds, in many ways, I told Nevala-Lee, like the archetypal UC student.
How so, he asked.
Arrogant, awkward, questioning yet has all the answers; inquisitive yet careerist.
'I mean, that describes Alvarez,' Nevala-Lee said. 'I think of him now as someone who understood how to get things done. But he was abrasive, didn't treat subordinates well — it was a problem. He would have gotten more accomplished if people didn't feel personally attacked by him so much. He assumed if you were in physics at his level, you get this treatment. Can't take it, find another field.'
Tack on a whimsical side — a study of UFOs, a study of pyramids, a genuine love for the science of the Superball by Wham-O — and Alvarez even sounds like a descendant of, well, Elon Musk. Nevala-Lee can see it. He was once enthralled himself by 'the American idea of visionary genius.' Nevala-Lee is 45 now, though younger, 'I had an exaggerated sense of my own abilities. I thought of myself as someone who could enter the world and solve its problems myself. Elon Musk was that guy about 10 years ago. I've since become pretty skeptical of this idea of a visionary genius. I don't know now if they ever did exist. Deep down, our figures like this, they all have the same problems.'
By the way, since you're probably wondering, for the record, Nevala-Lee is a nice guy.
cborrelli@chicagotribune.com
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The article is well researched and composed by a professional science and health writer who is also used to interpreting medical information presented in complex terms to clear and accessible language by anyone not limited to a specific background. The author has relied upon evidence-based practice since he has referred to peer-reviewed journals, literature textbooks, and reliable health organizations. The inspiration to compose this work was to enable the readers not only to acquire a technical knowledge about strepto penicillin but also have a historical and societal point of view, as it is regarded to have changed modern medicine. All the facts provided in this article have been checked cross-wise and at the end of all this checking, the reader knows that he/she is getting the best and the most updated facts. Strepto penicillin is the name that brings together two outstanding worlds of antibiotic research in science, the firstpenicillin that was found in molds and the next generation of antibiotics that is discovered in Streptomyces known as soil bacteria. Most people have heard about penicillin as the drug that transformed the field of medicine in the 20 th century but far less have heard about the significant contribution that Streptomyces species have made in the expanses of antibiotic therapy. Strepto penicillin itself is not a single drug, but an idea-one that can help span the gulf separating the fungal and bacterial esters pharmaceutical eontributions, the inspiration that brought about a pharmacopoeia of lifesaving substances. Strepto penicillin is a story quilt made of scientific discovery and industrial innovation, war-time needs, and forty years of ever-increasing research. It has a long history that intertwines with some of the most monumental events throughout the history of medicine, such as the widespread usage of antibiotics during World War II, to the advanced interventions in molecular biology popular in the 21st century. In the age of antibiotic resistance being one of the biggest challenges to the population, it would further make knowing the origins, mechanisms, and contemporary applications of strepto penicillin all the more crucial. This paper discusses the entire process, its history, structure, use, medical uses, manufacturing processes, and prospects of reducing antibiotic effectiveness in future generations with regards to the worldwide concern of retainingantibiotics usefulness to future generations. The saga of strepto penicillin started in the year 1928 when Alexander Fleming a bacteriologist of Scottish origin was something odd in his Petri dishes. 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Although penicillin is not produced by Streptomyces, feats in antibiotic production, purifications, and modifications discovered in the research of streptomyces contributed to the processes of penicillin derivatives development. Such derivatives would frequently have superior stability, extended antibacterial spectra, or be able to resist attack by bacterial enzymes that would normally inactivated penicillin. The combination of both fungal-derived and Streptomyces-modelled innovation provided greatly increased amounts of antibiotics in the toolbox of doctors and hospitals all over the world. The core of strepto penicillin like analogs is the four-membered cyclic amide (the beta-lactam monomer) that is essential to the mechanism of their antibacterial agents. This ring enables connection of such bacteria enzymes as penicillin-binding proteins (PBPs) to the antibiotic. The assembly of peptidoglycan layer structure of the bacterial cell walls is due to these enzymes. 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