logo
AstraZeneca signs AI research deal with China's CSPC for chronic diseases

AstraZeneca signs AI research deal with China's CSPC for chronic diseases

Business Recorder17 hours ago

AstraZeneca has signed an AI-led research agreement with China's CSPC Pharmaceutical Group worth up to $5.3 billion, which would help the Anglo-Swedish drugmaker develop therapies for chronic conditions, it said on Friday.
The deal marks the latest effort by AstraZeneca to revive its business in China, its second-biggest market, where it has faced several challenges including the arrest of its China president last year and potential fines related to imports.
Under Friday's agreement, the two companies will collaborate to discover and develop pre-clinical candidates, including a small molecule oral therapy for immunological diseases, with CSPC conducting AI-driven research in Shijiazhuang City.
'This strategic research collaboration underscores our commitment to innovation to tackle chronic diseases which impact over two billion people globally,' AstraZeneca executive Sharon Barr said in a statement.
Friday's agreement follows AstraZeneca's announcement in March that it will invest $2.5 billion in a R&D hub in Beijing, and it also marks further investment in AI following collaborations with Immunai, Qure.ai and Tempus AI.
AstraZeneca will pay CSPC an upfront fee of $110 million. The Hong Kong-listed firm is also eligible to receive up to $1.62 billion for reaching development milestones and $3.6 billion linked to sales-related milestones, the groups said in separate statements.
They signed a licensing deal last October in which AstraZeneca agreed to pay up to $1.92 billion to CSPC to develop a candidate which would boost its cardiovascular pipeline.
AstraZeneca and CSPC both have wide-ranging pipeline portfolios, including cancer treatments and those targeting cardiovascular diseases.
However, about 80% of CSPC's total revenue comes from its finished drug segment, according Morningstar analysts. The Chinese group said last month it was in negotiations with third parties on new licensing and collaboration.
Friday's agreement also gives AstraZeneca the rights to exercise options for exclusive licenses for candidates identified as part of the collaboration.

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Confusion reigns as PPP sends mixed signals on budget protest
Confusion reigns as PPP sends mixed signals on budget protest

Express Tribune

timean hour ago

  • Express Tribune

Confusion reigns as PPP sends mixed signals on budget protest

Confusion continues to swirl within the PPP over its purported plans to stage a nationwide protest against the federal budget, as conflicting voices emerge from within the party's ranks. While some insiders deny any such plan, others maintain that a strategy was indeed in the works, but mainly being driven by the party's Punjab wing, as the central party has not been fully engaged in the decision. The Pakistan Peoples Party, whose senior leader Chaudhary Manzoor announced a countrywide protest against the budget draft, remains a key coalition partner in the federal government. Without its backing, the PML-N-led government would be left out on a limb. Any official protest call by the party's central leadership would signal a withdrawal of support for the finance bill, throwing the budget's passage into serious doubt. However, party leaders The Express Tribune spoke to suggested that Manzoor's call was more of a solo flight than a coordinated party line. While some leaders in central Punjab are rallying behind it, the move has not received a formal green light from the party's top brass. According to insiders, the protest plan was being shaped as an attempt to tap into the growing discontent among farmers and labourers who were being left high and dry by the government's policies. The party, by reaching out to farmers and labourers, would try to gather support before embarking on any protest plan, as it lacks sufficient muscle in Punjab to hit the roads without them. Senior Vice President Central Punjab Rana Farooq Saeed said they had not been informed by the party about any protest plan. He questioned under whose authority Manzoor had made the call. However, he added that the party does not approve of the budget, as it offered nothing for farmers and labourers. "It would be wrong to even call it a budget," he said. However, despite these reservations, the party has yet to take a formal decision. "Given that we are allies in the centre, we cannot give out impulsive statements against the budget," he said. Central Party General Secretary Hasan Murtaza avoided giving a direct answer regarding any party plans to hold a protest demonstration throughout the country. He said they were allies of the government and would try to knock some sense into the PML-N over the glaring discrepancies in the budget. If dialogue failed, he added, they would ultimately hit the roads. When asked if the central party had rejected the budget, which would mean the PPP would withhold support, he said that decision would be taken by the central leadership. However, he clarified that the party would not "stand in for PML-N's mistakes". "They will not carry their weight while they suck the life out of poor people and line their own pockets," he said. He listed several grievances, from the failure to renegotiate capacity payments to the taxation of solar panels. When asked about senior leader Naveed Qamar's acknowledgement of thorough consultation sessions with the PML-N on the budget, he responded that "consultation does not mean that their inputs are being incorporated". On Thursday, several media outlets reported that the PPP had rejected the federal budget for the upcoming fiscal year and announced a nationwide protest campaign against it. The impression was formed after Chaudhary Manzoor Ahmad, who heads the PPP's People's Labour Bureau, lambasted the federal government at a press conference in Islamabad for presenting a budget that favours the wealthy and ignores the miseries of the working class and poor. The PPP leader said the party had started contacting trade unions across the country to mobilise support for protest demonstrations. He stated that demonstrations would be held in all provinces before the passage of the federal budget in the National Assembly. When senior PPP leader Naveed Qamar was asked to comment on the budget, he said the party recognised that the government was walking a tightrope under the IMF programme. However, he also said the government's policies were misaligned and that if the PPP were designing the budget, it would have been vastly different. At no point during the programme did he outright reject the budget or announce plans for protest rallies.

K-P proposes Rs157b surplus in Rs2.1tr budget
K-P proposes Rs157b surplus in Rs2.1tr budget

Express Tribune

time2 hours ago

  • Express Tribune

K-P proposes Rs157b surplus in Rs2.1tr budget

Listen to article The PTI-led Khyber-Pakhtunkhwa government on Friday presented a Rs2,119 billion surplus budget for fiscal year 2025-26, featuring no new taxes, a 10% salary increase, and a 7% pension hike for government employees. The budget session, presided over by Speaker Babar Salim Swati, began with the recitation of the Holy Quran. Khyber-Pakhtunkhwa Chief Minister Ali Ameen Gandapur, opposition leader Dr Ebad Khan, PPP parliamentary leader Ahmed Kundi and leaders of all parties were in attendance. At the outset of the session, opposition members gathered in front of the speaker's desk, carrying placards and banners bearing slogans against alleged corruption and nepotism in the province. Earlier, Governor Faisal Karim Kundi declined to immediately summon the budget session, stressing that he would not act under political pressure. He emphasized that while he was legally bound to respond within 14 days, there was no obligation to comply instantly, especially under what he termed undue influence from the chief minister or other quarters. The chief minister has sent a summary to the governor, requesting to convene the assembly's budget session, but the governor has chosen not to return the summary immediately, leading to a delay in scheduling the session. Presenting the annual budget, Finance Minister Aftab Alam announced that estimated expenditures for the fiscal year 2025-26 would total Rs1,962 billion, with a projected surplus of Rs157 billion. Providing a breakdown, he said the government expects to receive Rs292.340 billion from the federal government for the merged tribal districts. This includes Rs80 billion in current budget grants, Rs39.600 under the Annual Development Program (ADP), Rs50 billion through the Accelerated Implementation Programme (AIP), Rs42.740 billion as inter-provincial share, and Rs17 billion for Temporarily Displaced Persons (TDPs). The minister added that the province anticipates Rs3.293 billion from the Public Sector Development Programme (PSDP), Rs1,506.92 billion in federal transfers, Rs129 billion from provincial own-source revenues and Rs10.250 billion in other receipts, Rs291.340m from merged district receipts, and Rs177.188m in federal project assistance. He said Rs137.912 billion would be collected through the one percent share of the divisible pool allocated for the war on terror, Rs57.115 billion as straight transfers under gas and oil royalties, Rs58.151 billion from the windfall levy on oil, Rs34.580 billion as net hydel profit for current year, and Rs71.410 billion as net hydel profit arrears. The finance minister added that no new taxes have been imposed in the budget. Instead, the tax base has been broadened, with projected tax receipts of Rs83.500 billion and non-tax receipts of Rs45.500 billion for the upcoming fiscal year. Similarly, the other receipts of Rs10.25 billion would include capital receipts of Rs0.250 billion and Rs10 billion other ways and means and Rs1147.761 billion as federal tax assignment. The minister said the government has estimated Rs1,255 billion current expenditures for settled areas including Rs288.514 billion for provincial salaries, Rs288.609 billion tehsil salaries, Rs190.297 billion for pension, Rs334.028 billion for non-salary expenses, Rs65.657 billion on Medical Teaching Institutions (MTIs), Rs37.545 billion non-salary expenditure for tehsils, Rs40.350 billion capital expenditure and Rs10 billion under the head of "other ways and means". Similarly, the current expenditure of merged areas is estimated at Rs160 billion, including Rs56.842 billion for provincial salaries, Rs46.865 billion for tehsil salaries, Rs4.670 billion for pension, Rs24.285 billion for non-salary expenses, Rs17 billion for TDPs and Rs10.339b non-salary tehsil expenditure.

Ships warned to avoid Red Sea, log Hormuz voyages
Ships warned to avoid Red Sea, log Hormuz voyages

Business Recorder

time4 hours ago

  • Business Recorder

Ships warned to avoid Red Sea, log Hormuz voyages

ATHENS: Merchant shipping is continuing to pass through the Strait of Hormuz despite Israel's attacks on Iran on Friday, the multinational, US-led Combined Maritime Force said, although some shipowners were looking to avoid the region. Iran has in the past threatened to close the critical Strait of Hormuz to traffic in retaliation for Western pressure. Any closure of the Strait could restrict trade and impact global oil prices. 'The Strait of Hormuz remains open and commercial traffic continues to flow uninterrupted,' the Combined Maritime Force said in advisory, adding that events over the past day had increased the likelihood of regional conflict to 'significant'. Greece and Britain have advised their merchant shipping fleets to avoid sailing through the Gulf of Aden and to log all voyages through the Strait of Hormuz following Israel's attacks on Iran, documents seen by Reuters showed. 'We have reports that more ship owners are now exercising extra caution and are opting to stay away from the Red Sea and the Persian Gulf,' said Jakob Larsen, chief safety & security officer with shipping association BIMCO. If the United States is perceived to be involved in any attacks, 'the risk of escalation increases significantly', Larsen said. 'Such an escalation could include missile attacks on ships or laying of sea mines in the Strait (of Hormuz).'

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into the world of global news and events? Download our app today from your preferred app store and start exploring.
app-storeplay-store