A Startup Wants to Help Parents Rank Embryos for Longevity
Prospective parents using IVF will soon be able to rank embryos using genetic and other information in the hopes of extending the longevity of their offspring, according to the 25-year-old entrepreneur behind Nucleus Genomics, a DNA testing and analysis company.
'Lifespan has dramatically increased in the last 150 years,' said Kian Sadeghi, the company's founder and CEO. 'DNA testing to predict and reduce chronic disease can make it happen again.'
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Health Line
18 minutes ago
- Health Line
What to Know About High Functioning Schizophrenia
When a person's schizophrenia symptoms do not appear to interfere with their daily life, their condition may be referred to as high functioning schizophrenia. But this is not an official diagnosis. Schizophrenia is a complex and varied psychiatric disorder that affects each person differently. Some people have relatively mild symptoms that come and go. Others experience more severe, persistent symptoms that interfere with their daily lives. When a person with schizophrenia is able to live a mostly independent life, hold a job, and maintain relationships, their condition is often referred to as 'high functioning.' Language matters The term 'high functioning' doesn't have a clear medical definition. Some clinicians use it to refer to people who require a lower level of assistance for daily activities. But terms like 'high functioning' and 'low functioning' don't account for people's unique life circumstances, abilities, and strengths. It's best to avoid using this kind of language outside of a conversation with your healthcare professional. What is high functioning schizophrenia? High functioning schizophrenia is a term used when people with schizophrenia are able to function well in daily life despite their diagnosis. They may have milder symptoms, or they may have developed good coping mechanisms despite having more severe symptoms. It's important to note that 'high functioning' is a subjective term and not a clinical diagnosis. And the label doesn't necessarily reflect the severity of a person's symptoms. People with high functioning schizophrenia may still experience significant challenges and need continuous treatment and support. A person's level of functioning can be influenced by a range of factors, including: Symptom severity: People with fewer or less severe symptoms may be able to function better in daily life than those with more severe symptoms. Treatment response: Those who get timely, appropriate treatment are more likely to maintain good functioning. Research from 2020 suggests that early intervention may be linked to better long-term outcomes. Personal coping strategies: Some people develop strong coping strategies that allow them to effectively manage their symptoms and prevent those symptoms from having a major effect on their daily life. Strong support network: Those with very supportive family and friends may be able to function better in daily life than those who don't have this support. Lack of other mental or physical health conditions: Many people with schizophrenia have other mental or physical health conditions that make it more difficult to function in daily life. People who don't have another condition may appear higher functioning. Symptoms of high functioning schizophrenia Any person with schizophrenia, whether it's considered 'high' or low' functioning, can experience the same types of symptoms. Schizophrenia symptoms are divided into positive, negative, and cognitive symptoms. Positive symptoms are those that 'add' to your personality (in other words, they weren't there before the condition). These symptoms include those of psychosis, such as: hallucinations delusions disorganized thoughts and speech atypical motor behavior (e.g., catatonia) Negative symptoms 'take away' from your personality and involve five key areas: alogia (reduction in the number of words spoken) anhedonia (reduced experience of pleasure) asociality (reduced social activity) avolition (reduced goal-directed activity, due to decreased motivation) blunted affect (difficulty expressing emotions, such as diminished facial expressions) Cognitive symptoms may include issues with: focus and attention span working memory executive functioning The negative symptoms of schizophrenia are often more challenging to treat than the positive symptoms. For some people with schizophrenia, these negative symptoms persist, even when positive symptoms are well managed. Research from 2020 suggests that negative symptoms are associated with poorer outlook and long-term disability. While many people with high functioning schizophrenia do have negative symptoms, these symptoms may be less severe. Diagnosing high functioning schizophrenia In the Diagnostic and Statistical Manual of Mental Disorders, 5th ed. text revision (DSM-5-TR), schizophrenia is now listed as a spectrum disorder. This more accurately represents the condition's wide range of symptoms that can change over time. It's important to note that high functioning schizophrenia is not a clinical diagnosis. So, whether a person exhibits a higher or lower level of functioning, they still have to meet the same diagnostic criteria. A diagnosis of schizophrenia must include at least two of the following symptoms, with one of these symptoms being among the first three: delusions hallucinations disorganized speech severely disorganized or catatonic behavior negative symptoms The symptoms must occur frequently for at least 1 month, with some symptoms lasting for more than 6 months. In addition, you'll need to have experienced reduced functioning in one or more important areas of life, such as personal relationships, work, or self-care. Treating schizophrenia Schizophrenia is typically treated with antipsychotic medication as well as various types of therapies and skills training. Schizophrenia may be treated with the following: Atypical antipsychotics: Atypical, or second-generation, antipsychotics are the first-line treatment for schizophrenia. These medications lower dopamine levels in the brain, which helps target symptoms of psychosis. Cognitive behavioral therapy (CBT): CBT helps people with schizophrenia identify and fix unhelpful thought processes and behaviors. Social skills training: Social skills interventions help people with schizophrenia learn social and independent living skills. These may include classes covering interpersonal skills and medication management. Cognitive remediation: This intervention focuses on skills such as attention, memory, and flexible thinking. Social cognition training: This intervention targets skills such as social perception (understanding social cues or body language), emotion perception (identifying others' emotions), and theory of mind (identifying and understanding another person's mental state). Some people with high functioning schizophrenia may have achieved symptom remission after responding well to treatment. Symptom remission means that your symptoms are mild enough to not significantly interfere with your life. Research from 2018 suggests that symptom remission is possible in 20% to 60% of people with schizophrenia, but this depends on many complex factors.
Bloomberg
21 minutes ago
- Bloomberg
Bloomberg Daybreak: Trump-Musk Feud
On today's podcast: 1) Elon Musk and President Donald Trump engage in a public dispute the traded personal barbs and weighed down Tesla stock and Musk's personal wealth. The dispute began over differences on the GOP tax legislation, with Musk opposing the bill and Trump accusing Musk of being motivated by self-interest. After Tesla shares tanked 14% and Musk's personal wealth dropped by $34 billion, Musk signaled a willingness to cool tensions with Trump, responding to a user's advice to "cool off and take a step back for a couple days" with "Good advice." 2) Tensions appear to be easing between the US and China. President Trump and Chinese President Xi Jinping agreed to further trade talks to resolve disputes over tariffs and rare earth minerals. The two leaders had a 90-minute call, during which Trump acknowledged that the trade relationship with China had gotten "a little off track" but said they are now "in very good shape" with a trade deal. 3) Investors brace for a critical May Jobs Report. Traders are awaiting the key monthly nonfarm payrolls report, which may reinforce expectations that the Federal Reserve will cut interest rates at least twice this year.
Forbes
22 minutes ago
- Forbes
High-Yield Savings Account Rates Today: June 6, 2025
Rates on savings accounts are the same compared to one week ago. You can now earn as much as 5.84% on your savings. Searching for an account where you can save for a rainy day or retirement? Here's a look at some of the best savings rates you can find today. Related: Find the Best High-Yield Savings Accounts Of 2025 Traditional savings accounts, called "statement savings accounts" in the banking world, have been notorious for paying paltry interest in past years, especially after the Great Recession. That's changed more recently, and you can find rates 10-times higher than those offered by traditional financial institutions if you opt for an online bank or a credit union. The highest yield on a standard savings account with a $2,500 minimum deposit amount within the last week has been 5.84%, according to data from Curinos. If you spot a basic savings account with a rate in that ballpark, you've done well for yourself. Today's average APY for a traditional savings account is 0.22%, Curinos says. APY, or annual percentage yield, reflects the actual return your account will earn during one year. It accounts for compound interest, which is the interest that accrues on the interest in your account. High-yield savings accounts typically pay much more interest than conventional savings accounts. But the thing to know is you may have to jump through some hoops to earn that higher rate, such as becoming a member of a credit union or putting down a large deposit. On high-yield accounts requiring a minimum deposit of $10,000, today's best interest rate is 4.88%. That's about the same as last week. The average APY for those accounts is now 0.23% APY, unchanged from a week ago. On high-yield savings accounts with a minimum opening deposit of $25,000, the highest rate available today is 3.94%. You'll be in good shape if you can get an account offering a rate close to that. The current average is 0.24% APY for a high-yield account with a $25,000 minimum deposit. Interest rates on savings accounts typically fluctuate in response to other rate changes throughout the economy. Savings rates are primarily influenced by the Federal Reserve's rate moves, and the central bank has finally begun reducing its benchmark federal funds rate as inflation has fallen closer to the Fed's 2% goal. Financial institutions usually adjust borrowing and savings rates soon after the Fed changes rates. The Fed votes to adjust rates eight times per year during meetings of the Federal Open Market Committee (FOMC). Curinos determines the average rates for savings accounts by focusing on those intended for personal use. Certain types of savings accounts—such as relationship-based accounts and accounts designed for youths, seniors and students—are not considered in the calculation. The best high-yield savings account pays 5.84% now, according to Curinos data, so you'll want to aim for an account that delivers a yield in that ballpark. But rates aren't everything. You want an account that charges few fees, offers great customer service and has a track record of being a stable institution. Savings yields are variable and can change depending on economic conditions or a bank's particular financial need. Usually rates are influenced by the federal funds rate, meaning that a bank tends to raise or lower its rates along with the Fed. Online banks and credit unions tend to offer the best yields because they can pass along savings from low overhead while also striving to attract new customers.
