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What happens when you stop taking weight loss drugs like Mounjaro and Ozempic?
What happens when you stop taking weight loss drugs like Ozempic?
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North Wales Chronicle
18 minutes ago
- North Wales Chronicle
Michael Mosley's family reflect on one year since TV doctor's death
Mosley, who died aged 67 while on holiday with his wife Dr Clare Bailey Mosley on the Greek island of Symi last year, was known for popularising diets and fronting science programmes. His wife wrote on Instagram: 'It's hard to believe that a year has passed since we lost Michael. Not a day goes by without thinking of him – his warmth, his laughter, his endless curiosity about the world, and his deep love for our family. A post shared by Dr Clare Bailey Mosley (@drclarebaileymosley) 'This past year has been the hardest of our lives. Navigating the loss of someone so central to our hearts and our home has changed everything. We have missed him in the big moments and the small ones. But we have also felt incredibly supported. 'The outpouring of love, stories and memories from so many of you has meant more than we can ever say. We have taken real comfort in knowing just how many lives Michael touched – not only through his work, but through his kindness, humour, and deep desire to help people live well for longer.' The message thanked 'everyone who has reached out, shared their grief, and carried us with their compassion, thank you. Your messages, letters and acts of remembrance have helped us through the darkest days.' It continued: 'We are trying, as a family to look forward. To carry on the work Michael was so passionate about. To live with purpose and joy, as he would have wanted us to.' 'With love and deepest gratitude, Clare and the Mosley family.' Last month, the family set up a research project to honour his memory, announcing that a new clinical research fellowship will be established in partnership with King's College London and the Chronic Disease Research Foundation (CDRF) to help improve the nation's metabolic health. The Mosleys have been working with King's College London and the CDRF, who will administer the Michael Mosley Memorial Research Fund, to appoint a dedicated research scientist. Mosley, known for fronting BBC and Channel 4 documentaries on health and diet, popularised the 5:2 diet, a form of intermittent fasting, through his book The Fast Diet. His son Dr Jack Mosley, a GP registrar, who researched GLP-1 drug brands including Ozempic, Wegovy, Mounjaro and Zepbound with his father, has also written a book titled Food Noise: How Weight Loss Medication And Smart Nutrition Can Silence Your Cravings. In December, a coroner said Mosley's death was 'indeterminate' and 'unascertainable', adding that it 'was most likely attributable either to heatstroke (accidental) or non-identified pathological cause'. Mosley had presented BBC Radio 4's Just One Thing, and the BBC series Trust Me, I'm A Doctor, which looked at healthcare in Britain. He would regularly push his body during various programmes, and in a 2014 documentary he ingested tapeworms for six weeks. In a 2015 programme he made two black puddings out of his own blood to showcase its nutritional value. The BBC honoured the doctor-turned-science broadcaster with a day dedicated to him in July 2024, when presenters and audiences where encouraged to do 'just one thing' to improve their wellbeing. His wife Clare accepted the Hall of Fame Award at the British Podcast Awards on his behalf in September 2024.
Daily Record
an hour ago
- Daily Record
Women taking weight-loss jabs given contraception warning as pregnancies rise
The Medicines and Healthcare products Regulatory Agency (MHRA) issued its first alert to the public regarding contraception and weight loss and diabetes jabs following concerns they may not be used safely Women using weight-loss injections are being urged to ensure they're on reliable birth control. The Medicines and Healthcare products Regulatory Agency (MHRA) has sounded an alarm over the use of contraception in tandem with weight loss and diabetes injections, citing safety concerns for the first time. These injections, which have been associated with a "baby boom", have led to reports of so-called "Ozempic babies" among women who believed they were protected by contraceptives. The MHRA has logged over 40 instances of pregnancies in women taking these medications to date. Concerns have also been raised about the absence of data regarding the safety of these injections during pregnancy, affecting drugs like Ozempic, Mounjaro, Wegovy, Saxenda, and Victoza. According to the MHRA, these medications – known as glucagon-like peptide-1 receptor agonists (GLP-1 or GLP-1 RAs) – should not be used while pregnant, attempting to conceive, or breastfeeding. The agency advises that anyone who becomes pregnant while on these drugs should discontinue their use immediately. The MHRA warns: "This is because there is not enough safety data to know whether taking the medicine could cause harm to the baby." In certain situations, women are also recommended to maintain contraceptive measures for up to two months after ceasing the medication before trying to conceive. Effective contraception methods, as outlined by the MHRA, include the oral contraceptive pill, contraceptive implants, intrauterine devices (IUDs), and condoms. Patients on Mounjaro, which can reduce the effectiveness of oral contraceptives in overweight individuals, are being urged to utilise condoms alongside the pill. The MHRA emphasised: "This only applies to those taking Mounjaro and is especially important for the four weeks after starting Mounjaro and after any dose increase." These advisements fall in line with guidance provided in the patient information leaflets included with the medication. An MHRA review has highlighted 26 pregnancy-related reports associated with Mounjaro use, although it is not mandated for women to disclose if the pregnancy was unplanned; nevertheless, one such report was made. Additionally, semaglutide (found in Ozempic and Wegovy) has been linked to eight pregnancy reports, while liraglutide (in Victoza or Saxenda) has seen nine, with one confirmed as unintended. In a bid to enhance safety, the MHRA is issuing a reminder that weight-loss injections should never be purchased from unlicensed vendors like beauty parlours or through social media platforms and ought to be used only following consultation with healthcare professionals. The regulator encourages anyone who experiences adverse reactions or doubts about the authenticity of their medication to make a report through the MHRA Yellow Card scheme. Dr Alison Cave, MHRA chief safety officer, made it clear: "Skinny jabs are medicines licensed to treat specific medical conditions and should not be used as aesthetic or cosmetic treatments." The medications regulator cautioned: "They are not a quick fix to lose weight and have not been assessed to be safe when used in this way." The authority also stated: "Our guidance offers patients a 'one-stop shop' for our up-to-date advice on how to use these powerful medicines safely." However, they emphasized that: "This guidance should not be used as a substitute to reading the patient information leaflet or having a conversation with a healthcare professional as part of the prescribing process." Additionally, the latest guidance highlights the need for patients taking these injections to be aware of the symptoms of acute pancreatitis, a rare but potentially serious condition. The primary symptom to look out for is severe stomach pain that radiates to the back and persists, and those experiencing it should seek immediate medical attention. GLP-1 and GLP-1 RAs function by mimicking a natural hormone released after eating, helping individuals feel fuller and more satisfied. Certain medications, such as Mounjaro, also target a second hormone involved in appetite and blood sugar regulation. Jasmine Shah, a medication safety officer at the National Pharmacy Association, advised: "Pharmacists urge women taking GLP-1 medicines to note this important new guidance from the MHRA published today and use effective contraception." She further noted: "Community pharmacies have been experiencing unprecedented levels of interest for weight loss injections. "It is therefore important that regulations and guidance keep pace with this demand and that patient safety is put at the heart of everything we do. "Medicines are not like ordinary goods for sale; they must be handled with great care because they have the power to harm as well as to heal. "We also reiterate warnings from the MHRA to avoid any potential fake weight loss injections sold on social media or via beauty salons, which could pose a serious risk to someone's health. "We urge anyone who have concerns about this medication to speak to their pharmacist for advice."
ITV News
2 hours ago
- ITV News
Pregnancy warnings for women on weight-loss jabs over 'Ozempic baby boom'
Women taking weight-loss jabs have been warned to make sure they are using effective contraception, amid reports of surprise "Ozempic babies" for those using birth control. The injections have been previously linked to a 'baby boom', with women reporting online that they have had fallen pregnant while using the drugs, despite using contraception. The Medicines and Healthcare products Regulatory Agency (MHRA) has issued its first alert to the public regarding contraception and weight-loss injections. It warned the drugs should not be taken during pregnancy, while trying to get pregnant, or during breastfeeding, due to a lack of safety data about harms caused to babies. To date, the regulator has received more than 40 reports relating to pregnancy among women on the drugs. Those patients taking Mounjaro, which may reduce the effectiveness of oral contraceptives in people who are overweight, should also use condoms if they are on the pill. The MHRA said: 'This only applies to those taking Mounjaro and is especially important for the four weeks after starting Mounjaro and after any dose increase.' MHRA data shows it has received 26 pregnancy-related reports for Mounjaro. It is not necessary for women to say whether the pregnancy was unintentional, though one report did say the pregnancy was such. There have been a further eight reports relating to pregnancy in people taking semaglutide (the ingredient in Ozempic and Wegovy). A further nine have been recorded for liraglutide (Victoza or Saxenda), of which one recorded the pregnancy was unintentional. There are also warnings over a lack of evidence for pregnancy safety for the jabs, which include Ozempic, Mounjaro, Wegovy, Saxenda and Victoza. In some cases, women are also advised to continue using contraception for up to two months between stopping the medicine and trying to get pregnant. The MHRA said effective contraception includes the oral contraceptive pill, contraceptive implants, the coil and condoms. The regulator also stressed that weight-loss jabs should not be bought from unregulated sellers such as beauty salons or via social media, or taken without speaking to a health professional. In May, an ITV News investigation uncovered videos of an NHS employee on social media illegally promoting weight-loss jabs. When the injectible pens were bought and tested, the substance was found to be unfit for human use. Undercover journalists also filmed at a "skinny jab party", where unlicensed weigh-loss injections containing ten times the recommended semaglutide dosage were being illegally sold. Anyone who suspects they have had an adverse reaction or suspects their drug is not a genuine product, should report it to the MHRA Yellow Card scheme. Dr Alison Cave, MHRA chief safety officer, said: 'Skinny jabs are medicines licensed to treat specific medical conditions and should not be used as aesthetic or cosmetic treatments. 'They are not a quick fix to lose weight and have not been assessed to be safe when used in this way." The latest guidance also reminds patients taking jabs of the symptoms to look out for in the event of acute pancreatitis which, although uncommon, can be serious. The main symptom is severe pain in the stomach that radiates to the back and does not go away, and people should seek immediate medical help.
