
The subtle clue in your EYE that could mean you'll get dementia as young as 45
Experts from New Zealand found that people were far more likely to be diagnosed with the disease in their 60s, 50s an even 40s if the light sensitive tissue at the back of the eye was abnormally thin.
This problem is known medically as retinal thinning, and causes distorted vision which includes seeing spots, lines or flashing lights, as well as changes in colour perception.
Dementia risk was also raised in those with signs of narrowing arteries and wider veins in the eye, which can cause pain or pressure as well as loss of vision in one eye.
The researchers, from the University of Otago, suggested that both problems suggest insufficient blood flow to both the eye and the brain, which could contribute to the development of the memory robbing condition.
They added that it could also be a sign of poor circulation throughout the body, which is also a known risk factor for the disease, as well as heart attack and stroke.
Thorough eye examinations could therefore be a useful method of targetting those at risk of developing the disease, according to study author and psychology researcher Dr Ashleigh Barrett-Young.
Early diagnosis is considered critical for better outcomes as dementia treatments can combat symptoms and slow down progression.
For the study, experts analysed data from participants of the Dunedin Multidisciplinary Health and Development Study, which recorded 45 years of health data from 900 New Zealanders with an average age of 45-years-old.
They combined photos and scans of participants' retinas with cognitive tests designed to predict a person's risk of the disease.
Assessments were carried out at birth and ages three, five, seven, nine, 11, 13, 15, 18, 21, 26, 32, 38, and most recently at age 45.
Results showed those with retinal thinning and poor eye blood vessel health were far more likely to show signs of cognitive decline aged 45 — often a precursor to dementia.
The researchers advised that the imaging could be a simple and low-cost method of assessing dementia risk among middle-aged adults.
However they warned the test could only show potential risk and is not a definitive diagnosis.
Around 900,000 Britons are currently thought to have the memory-robbing disorder. The researchers advised that the imaging could be a simple and low-cost method of assessing Alzheimer's disease and related dementias among middle-aged adults
The size of your temporalis muscle, which helps to open and close your jaw, has also been linked to dementia risk.
It's estimated that around 7.5 per cent of the 944,000 Britons with the disease have young-onset dementia, where symptoms occur younger than 65.
Alzheimer's is the most common form of dementia in younger people, accounting for around a third, in comparison to about 60 per cent in those over 65.
Memory problems, thinking and reasoning difficulties and language problems are common early symptoms of the condition, which then worsen over time.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Scottish Sun
a day ago
- Scottish Sun
Common pill taken by millions could ‘slash your risk of dementia and dying young'
Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) A CHEAP pill already taken by millions of patients could slash your risk of dementia and early death, scientists say. This is none other than metformin, "the most widely prescribed drug for type 2 diabetes", according to researchers from Taipei Medical University in Taiwan. Sign up for Scottish Sun newsletter Sign up 1 Diabetes pill metformin could lower the risk of dementia and death Credit: Alamy They found that people who were taking the treatment were less likely to develop memory-robbing dementia or die from any cause. The results were based on a study of 452,777 adults who were either overweight or obese, published in Diabetes, Obesity and Metabolism. Obesity and diabetes have both been shown to up the risk of dementia. Some studies report that diabetics have a 70 per cent higher risk of getting the condition, compared to those without diabetes. Meanwhile, being obese between the ages of 35-65 can increase dementia risk in later-life by about 30 per cent. Metformin is the most common treatment for type 2 diabetes, which affects over 5 million Brits, according to Diabetes UK. The drug is also used to help prevent type 2 diabetes in people at high risk of developing it. It works by curbing the amount of sugar pumped around the body by the liver and helping the insulin you produce work better. "Metformin has many advantages over other diabetic drugs. It has strong glucose-lowering effects, a reliable safety profile and is relatively cheap," researchers said. "Metformin also reduces the likelihood of dementia in patients with diabetes." Common painkiller used for back pain ups risk of dementia by 29%, scientists warn But some studies suggest the drug doesn't protect against dementia, as it can cause vitamin B12 deficiency, which has been linked to cognitive decline. It could increase the risk of Alzheimer's, a type of dementia, research suggests. "Whether metformin's beneficial effects in patients with dementia can be applied to the general population is unclear," the study authors noted. The study included about 905,000 people in total, split evenly into two groups: metformin users and non-metformin users. They were matched to be similar in age, health, and other factors for a fair comparison. The metformin group had been prescribed the drug at least twice in their lives, for at least six months. Researchers categorised study participants by their body mass index (BMI) as: Overweight: BMI 25–29.9 Obese class I: BMI 30–34.9 Obese class II: BMI 35–39.9 Morbidly obese: BMI over 40 They followed patients for 10 years and found that those who took metformin had a lower risk of developing dementia, regardless of their BMI. Class I and II obese patients saw the greatest reduction in risk - 8 and 4 per cent respectively, compared to people who didn't take metformin. Ways to lower dementia risk with type 2 diabetes Manage blood sugar levels Strictly follow a diabetes management plan, as prescribed by a healthcare professional. This includes medication, diet and exercise. Regularly monitor blood sugar levels and manage insulin appropriately. Adopt a healthy lifestyle Follow a balanced diet in fruits, vegetables, whole grains, and lean protein, with limited saturated fat, sugar, and salt. Aim for at least 150 minutes of moderate-intensity exercise per week. Being overweight or obese can increase the risk of type 2 diabetes and other conditions linked to dementia. Weight management through diet and exercise can help mitigate these risks. Engage in activities that challenge your mind, such as puzzles, reading, learning new skills, or socialising. Address other risk factors High blood pressure and cholesterol can damage blood vessels, increasing the risk of both cardiovascular disease and dementia. Regular check-ups and appropriate treatment are essential. Excessive alcohol consumption can negatively impact brain health. Moderate drinking or abstaining from alcohol can be beneficial. Hearing loss can contribute to cognitive decline. Addressing hearing problems through hearing aids or other interventions can help maintain cognitive function. Seek professional guidance Regular medical check-ups are important for monitoring overall health and identifying and addressing potential risk factors early on. Work with your doctor, diabetes educator, or other healthcare professionals to develop a personalized plan for managing your diabetes and reducing your risk of dementia. Researchers said the drug's ability to lower inflammation in obese patients may have something to do with this. "Since central nervous system inflammation and neuroinflammation are crucial factors in the development and progression of neurodegenerative diseases, the anti-inflammatory and antioxidative effects of metformin are especially beneficial in patients with obesity," they wrote. "We observed that the protective effect of metformin against dementia was consistent across all BMI categories greater than 25." Metformin-users also had a lower risk of early death, between 28 and 26 per cent. "This study is strong because it included a large sample of metformin users and patients with obesity and dementia, using data from more than 184 million patients worldwide," researchers said. "The use of real-world data allows for a better understanding of how treatments perform in a heterogeneous population because the data are captured from diverse, real-life settings. "Therefore, the findings of this study can be readily generalised to whole populations." But they acknowledge that their study had certain limitations too, including that the dataset only covered a 10 year period, restricting researchers' ability to evaluate the long-term effects of metformin. They concluded: "Our study findings indicate that metformin may help reduce the risk of dementia in obese patients, which could further contribute to improving all-cause mortality. "However, further research is required to explore the mechanisms by which metformin reduces the risk of dementia." Experts have previously suggested that using metformin to help treat dementia could cut costs. Dr Sara Imarisio, who used to be head of research at Alzheimer's Research UK, said: 'Repurposing an existing drug used for another health condition would be a cheaper and inexpensive way to bring about a new dementia treatment. 'Diabetes is a risk factor for dementia and there is a lot of interest in the links between the two conditions." But recent research suggests that weight-loss jabs are better at curbing dementia risk in people with type 2 diabetes than metformin. Metformin is generally the first-line medication for type 2 diabetes, while GLP-1 receptor agonists are often used as second-line or add-on therapy when metformin is not sufficient or tolerated.


Daily Mirror
a day ago
- Daily Mirror
Alzheimer's and dementia 'risk increases due to one common sleep issue'
Interrupted sleep can cause damage to the brain's blood vessels, a new study claims. Broken and disturbed sleep could leave you vulnerable to developing dementia, groundbreaking research has revealed. Experts from the University of Toronto discovered disrupted sleep can inflict harm on the brain's blood vessels after studying more than 600 elderly participants. The volunteers wore smartwatch-style devices to monitor their sleep patterns and underwent genetic testing to assess pericyte levels in their brains. Following their deaths, they donated their brains for scientific examination. "We found that individuals who had more fragmented sleep, such as sleeping restlessly and waking up a lot at night, had a change in their balance of pericytes - a brain blood vessel cell that plays an important role in regulating brain blood flow and the entry and exit of substances between the blood and the brain," Andrew Lim, principal investigator of the study, said, reports the Express. Mr Lim added: "This in turn was associated with more rapid decline in cognitive function in the decade leading up to their death." Addressing sleep disruption could offer a pathway to enhancing brain vascular health, the research concluded. Mr Lim said: "We know that in some individuals, sleep disruption can precede the onset of cognitive impairment by years, with emerging evidence suggesting a bidirectional link between sleep disruption and Alzheimer's disease." Nevertheless, until this point, researchers "didn't have sufficient evidence behind the mechanisms underlying these links", he clarified. The research team examined "predominantly older women of European ancestry", so recommended future studies in different populations would be beneficial to establish how widely applicable the findings are. The NHS recommends a healthy adult typically requires around seven to nine hours of sleep each night. Nevertheless, factors including age, health and individual circumstances all influence how much sleep is required. Some people "naturally sleep more than others" according to the NHS. Infants, children, and teens require more sleep than adults as they are still developing. If you discover you feel constantly exhausted during the day, you're likely not getting sufficient sleep. There are currently believed to be nearly one million people across the UK living with dementia, yet more than a third of these individuals lack a formal diagnosis. Dementia is the term for a collection of symptoms and Alzheimer's is the most prevalent cause - but what exactly are the warning signs? The initial noticeable indicator is frequently memory difficulties - and someone with Alzheimer's may struggle to recall recent occurrences or absorb new information, the Alzheimer's Society explained. Someone with the condition might also experience difficulties with focus, planning, and organisation, and may find themselves bewildered about the time of day or their location. Shifts in temperament - they may become more worried, dejected, or easily irritated - and communication challenges can be typical in someone with the condition.


Daily Mirror
2 days ago
- Daily Mirror
'I suffered the hard way after everyone begged me not to have boob job in Turkey'
Chloe Roiser, a nurse from Wymondham, Norfolk, spent seven weeks in hospital in Turkey recovering from a botched boob job, after which she collapsed and battled necrosis A British nurse who ignored her family's warnings about having a boob job in Turkey nearly died following the botched surgery. Chloe Roiser, 31, has lost half of her left nipple due to necrosis, which happened as a result of the operation at a clinic in Antalya. Chloe spent seven weeks in hospital in Turkey fighting a flesh-eating infection - treatment which cost £12,000 - and became extremely unwell during this period. She is now back home in Wymondham, Norfolk, but has warned others not to travel abroad for cosmetic surgery. Speaking yesterday, the mum of five said: "Going to Turkey for cosmetic surgery has been a nightmare from which I thought I'd never wake up... I'm very lucky I didn't lose my whole breast or, far worse, develop sepsis and die, leaving my precious kids without their mum." The woman is speaking out as a major crackdown on cosmetic cowboys has finally been announced by the UK government - following the Mirror's campaign. And during Chloe's plight, her teenage daughter flew out to be at her bedside. The youngster wept and pleaded: "Mum, please don't die" during heartbreaking scenes in April. In fact, Chloe made two trips to the Antalya clinic. A week after the operation, Chloe, a trained nurse, came home but then became "very unwell" with fever and pain. When her breast began oozing discharge in early June, she made an emergency dash back to Turkey – accompanied by her partner and daughter as she was too weak to walk unaided or carry her own bag – for medical treatment. The mum said she didn't want to burden the NHS with the fall-out from cosmetic surgery in another country – but she also feared doctors here would simply take the implant out and hoped, by returning to Turkey, she could save it. On three separate occasions, the surgeon, who had performed the original operation, cleared the infection and the necrotised skin on her breast using a scalpel – meaning she lost half her left nipple. Chloe later collapsed and her fight for life in hospital began. Reflecting on this, the 31-year-old woman told Mail Online: "I'm a nurse so I know all too well how deadly an untreated infection and necrosis can be. The thought of dying and leaving my children without a mum, just so I could bear to look at myself undressed in a mirror and go swimming again – neither of which I'd had the confidence to do for years – is just unbearable. "Everyone, friends, my mum, warned me not to go to Turkey for the surgery – so many knew people with horror stories – but I spent a year researching it and honestly thought, given my medical knowledge and training, I'd be safe." An estimated 150,000 Britons travel to Turkey each year for cut-price cosmetic procedures, having discovered that a breast uplift and size D implants would cost around £3,500 – half the price it would have set her back here. But Chloe, who at one point looked as though she'd lose her whole left breast, advises Brits against this. She admits she now "couldn't care less how they (her breasts) look." The graduate continued: "I owe my family and friends, who dipped into their savings to support me, so much money. I'm determined to pay it back but I don't know how long it will be until I'm fit to work again. "It's not just the physical toll but the emotional toll this has taken on me. I've been left feeling so anxious I'm constantly on the verge of a panic attack."