Mosquitoes test positive for West Nile virus on Long Island
The 14 positive mosquito samples were taken in Nesconset, Northport, Dix Hills, Melville, Lindenhurst, West Babylon, St. James, Rocky Point and Holtsville, Suffolk County Health Commissioner Dr. Gregson Pigott announced Monday.
The samples were collected on July 16.
To date, Suffolk has reported 15 mosquito samples testing positive for West Nile virus and four testing positive for Jamestown Canyon virus, Pigott said.
"Mosquito activity is picking up with the warmer weather and with it comes the risk of being exposed to West Nile virus," Pigott said. "While there is no cause for alarm, we advise residents to take precautions and cooperate with us in our efforts to reduce exposure to mosquito-borne diseases."
West Nile has also been detected in mosquitoes in New York City this year, as experts track a rise in cases nationwide. Suffolk did not report any human cases and neither did the city.
West Nile virus has been detected in Suffolk County every year since 1999, when it first appeared, the County Department of Health Services said. There were 21 confirmed cases in 2024 and five in 2023. Two people in New Jersey died from the virus last year.
The virus is transmitted to humans when they are bitten by an infected mosquito.
"Most people infected with West Nile virus will experience mild or no symptoms, but some can develop severe symptoms including high fever, headache, neck stiffness, stupor, disorientation, coma, tremors, convulsions, muscle weakness, vision loss, numbness, and paralysis. The symptoms may last several weeks, and neurological effects may be permanent. Individuals, especially those 50 years or older or those with compromised immune systems, are urged to take precautions to avoid being bitten by mosquitoes," according to the county's health department.
Suffolk's health commissioner released these tips for preventing mosquito bites:
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GAAP and non-GAAP SG&A expenses decreased in the second quarter of 2025, compared to the second quarter of 2024, primarily due to lower charitable contributions to an independent not-for-profit patient assistance organization. GAAP and non-GAAP gross margin on net product sales decreased in the second quarter of 2025, compared to the second quarter of 2024, partly due to ongoing investments to support the Company's manufacturing operations and higher inventory write-offs and reserves in the second quarter of 2025 compared to the second quarter of other income (expense), net included the recognition of net unrealized gains on equity securities of $250 million in the second quarter of 2025, compared to $393 million in the second quarter of 2024. In the second quarter of 2025, the Company's GAAP effective tax rate (ETR) was 8.4%, compared to 12.0% in the second quarter of 2024. 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These non-GAAP financial measures are computed by excluding certain non-cash and/or other items from the related GAAP financial measure. The Company also includes a non-GAAP adjustment for the estimated income tax effect of reconciling items. A reconciliation of the Company's GAAP to non-GAAP results is included in Table 3 of this press Company makes such adjustments for items the Company does not view as useful in evaluating its operating performance. For example, adjustments may be made for items that fluctuate from period to period based on factors that are not within the Company's control (such as the Company's stock price on the dates share-based grants are issued or changes in the fair value of the Company's investments in equity securities) or items that are not associated with normal, recurring operations (such as acquisition and integration costs). Management uses these non-GAAP measures for planning, budgeting, forecasting, assessing historical performance, and making financial and operational decisions, and also provides forecasts to investors on this basis. With respect to free cash flow, the Company believes that this non-GAAP measure provides a further measure of the Company's ability to generate cash flows from its operations. Additionally, the non-GAAP measures presented are intended to provide investors with an enhanced understanding of the financial performance of the Company's core business operations. However, there are limitations in the use of these and other non-GAAP financial measures as they exclude certain expenses that are recurring in nature. Furthermore, the Company's non-GAAP financial measures may not be comparable with non-GAAP information provided by other companies. Any non-GAAP financial measure presented by the Company should be considered supplemental to, and not a substitute for, measures of financial performance prepared in accordance with GAAP. (b) The Company's 2025 financial guidance does not assume the completion of any business development transactions not completed as of the date of this press release. (c) Gross margin on net product sales represents gross profit expressed as a percentage of total net product sales recorded by the Company. Gross profit is calculated as net product sales less cost of goods sold. (d) Corresponding reimbursements from collaborators and others for manufacturing product is recorded within revenues. Conference Call Information Regeneron will host a conference call and simultaneous webcast to discuss its second quarter 2025 financial and operating results on Friday, August 1, 2025, at 8:30 AM Eastern Time. Participants may access the conference call live via webcast, or register in advance and participate via telephone, on the "Investors and Media" page of Regeneron's website at Upon registration, all telephone participants will receive a confirmation email detailing how to join the conference call, including the dial-in number along with a unique passcode and registrant ID that can be used to access the call. A replay of the conference call and webcast will be archived on the Company's website for at least 30 days. About Regeneron Regeneron is a leading biotechnology company that invents, develops, and commercializes life-transforming medicines for people with serious diseases. Founded and led by physician-scientists, Regeneron's unique ability to repeatedly and consistently translate science into medicine has led to numerous approved treatments and product candidates in development, most of which were homegrown in Regeneron's laboratories. Regeneron's medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurological diseases, hematologic conditions, infectious diseases, and rare diseases. Regeneron pushes the boundaries of scientific discovery and accelerates drug development using its proprietary technologies, such as VelociSuite®, which produces optimized fully human antibodies and new classes of bispecific antibodies. Regeneron is shaping the next frontier of medicine with data-powered insights from the Regeneron Genetics Center® and pioneering genetic medicine platforms, enabling Regeneron to identify innovative targets and complementary approaches to potentially treat or cure diseases. For more information, please visit or follow Regeneron on LinkedIn, Instagram, Facebook, or X. Forward-Looking Statements and Use of Digital Media This press release includes forward-looking statements that involve risks and uncertainties relating to future events and the future performance of Regeneron Pharmaceuticals, Inc. ("Regeneron" or the "Company"), and actual events or results may differ materially from these forward-looking statements. Words such as "anticipate," "expect," "intend," "plan," "believe," "seek," "estimate," variations of such words, and similar expressions are intended to identify such forward-looking statements, although not all forward-looking statements contain these identifying words. These statements concern, and these risks and uncertainties include, among others, competing drugs and product candidates that may be superior to, or more cost effective than, products marketed or otherwise commercialized by Regeneron and/or its collaborators or licensees (collectively, "Regeneron's Products") and product candidates being developed by Regeneron and/or its collaborators or licensees (collectively, "Regeneron's Product Candidates") (including biosimilar versions of Regeneron's Products); uncertainty of the utilization, market acceptance, and commercial success of Regeneron's Products and Regeneron's Product Candidates and the impact of studies (whether conducted by Regeneron or others and whether mandated or voluntary) or recommendations and guidelines from governmental authorities and other third parties or other factors beyond Regeneron's control on the commercial success of Regeneron's Products and Regeneron's Product Candidates; the nature, timing, and possible success and therapeutic applications of Regeneron's Products and Regeneron's Product Candidates and research and clinical programs now underway or planned, including without limitation EYLEA HD® (aflibercept) Injection 8 mg, EYLEA® (aflibercept) Injection, Dupixent® (dupilumab), Libtayo® (cemiplimab), Praluent® (alirocumab), Kevzara® (sarilumab), Evkeeza® (evinacumab), Veopoz® (pozelimab), Ordspono™ (odronextamab), Lynozyfic™ (linvoseltamab), other clinical programs discussed in this press release, Regeneron's and its collaborators' earlier-stage programs, and the use of human genetics in Regeneron's research programs; the likelihood and timing of achieving any of the anticipated milestones described in this press release; safety issues resulting from the administration of Regeneron's Products and Regeneron's Product Candidates in patients, including serious complications or side effects in connection with the use of Regeneron's Products and Regeneron's Product Candidates in clinical trials; the likelihood, timing, and scope of possible regulatory approval and commercial launch of Regeneron's Product Candidates and new indications for Regeneron's Products, including those listed above and/or otherwise discussed in this press release; the extent to which the results from the research and development programs conducted by Regeneron and/or its collaborators may be replicated in other studies and/or lead to advancement of product candidates to clinical trials, therapeutic applications, or regulatory approval; ongoing regulatory obligations and oversight impacting Regeneron's Products, research and clinical programs, and business, including those relating to patient privacy; determinations by regulatory and administrative governmental authorities which may delay or restrict Regeneron's ability to continue to develop or commercialize Regeneron's Products and Regeneron's Product Candidates; the ability of Regeneron to manufacture and manage supply chains for multiple products and product candidates and risks associated with tariffs and other trade restrictions; the ability of Regeneron's collaborators, suppliers, or other third parties (as applicable) to perform manufacturing, filling, finishing, packaging, labeling, distribution, and other steps related to Regeneron's Products and Regeneron's Product Candidates; the availability and extent of reimbursement or copay assistance for Regeneron's Products from third-party payors and other third parties, including private payor healthcare and insurance programs, health maintenance organizations, pharmacy benefit management companies, and government programs such as Medicare and Medicaid; coverage and reimbursement determinations by such payors and other third parties and new policies and procedures adopted by such payors and other third parties; changes in laws, regulations, and policies affecting the healthcare industry; unanticipated expenses; the costs of developing, producing, and selling products; the ability of Regeneron to meet any of its financial projections or guidance and changes to the assumptions underlying those projections or guidance, including GAAP and non-GAAP R&D, GAAP and non-GAAP SG&A, GAAP and non-GAAP gross margin on net product sales, COCM, capital expenditures, and GAAP and non-GAAP ETR; the potential for any license or collaboration agreement, including Regeneron's agreements with Sanofi and Bayer (or their respective affiliated companies, as applicable), to be cancelled or terminated; the impact of public health outbreaks, epidemics, or pandemics on Regeneron's business; and risks associated with litigation and other proceedings and government investigations relating to the Company and/or its operations (including the pending civil proceedings initiated or joined by the U.S. Department of Justice and the U.S. Attorney's Office for the District of Massachusetts), risks associated with intellectual property of other parties and pending or future litigation relating thereto (including without limitation the patent litigation and other related proceedings relating to EYLEA), the ultimate outcome of any such proceedings and investigations, and the impact any of the foregoing may have on Regeneron's business, prospects, operating results, and financial condition. A more complete description of these and other material risks can be found in Regeneron's filings with the U.S. Securities and Exchange Commission, including its Form 10-K for the fiscal year ended December 31, 2024 and its Form 10-Q for the quarterly period ended June 30, 2025. Any forward-looking statements are made based on management's current beliefs and judgment, and the reader is cautioned not to rely on any forward-looking statements made by Regeneron. Regeneron does not undertake any obligation to update (publicly or otherwise) any forward-looking statement, including without limitation any financial projection or guidance, whether as a result of new information, future events, or otherwise. Regeneron uses its media and investor relations website and social media outlets to publish important information about the Company, including information that may be deemed material to investors. Financial and other information about Regeneron is routinely posted and is accessible on Regeneron's media and investor relations website ( and its LinkedIn page ( Non-GAAP Financial Measures This press release and/or the financial results attached to this press release include amounts that are considered "non-GAAP financial measures" under SEC rules. As required, Regeneron has provided reconciliations of such non-GAAP financial measures. Contact Information: Ryan Crowe Christina Chan Investor Relations Corporate Affairs 914-847-8790 914-847-8827 TABLE 1 REGENERON PHARMACEUTICALS, CONSOLIDATED BALANCE SHEETS (Unaudited) June 30, December 31, 2025 2024 Assets: Cash and marketable securities $ 17,527.8 $ 17,912.6 Accounts receivable, net 5,610.0 6,211.9 Inventories 3,205.6 3,087.3 Property, plant, and equipment, net 4,840.7 4,599.7 Intangible assets, net 1,351.7 1,148.6 Deferred tax assets 3,572.2 3,314.1 Other assets 2,111.2 1,485.2 Total assets $ 38,219.2 $ 37,759.4 Liabilities and stockholders' equity: Accounts payable, accrued expenses, and other liabilities $ 4,887.0 $ 4,888.0 Finance lease liabilities 720.0 720.0 Deferred revenue 688.2 813.4 Long-term debt 1,985.1 1,984.4 Stockholders' equity 29,938.9 29,353.6 Total liabilities and stockholders' equity $ 38,219.2 $ 37,759.4 TABLE 2 REGENERON PHARMACEUTICALS, CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) Three Months Ended June 30, Six Months Ended June 30, 2025 2024 2025 2024 Revenues: Net product sales $ 1,631.0 $ 1,918.6 $ 3,046.6 $ 3,679.9 Collaboration revenue 1,860.7 1,524.0 3,391.9 2,790.8 Other revenue 183.9 104.5 265.8 221.4 3,675.6 3,547.1 6,704.3 6,692.1 Expenses: Research and development 1,421.7 1,200.0 2,749.1 2,448.4 Acquired in-process research and development 10.0 23.9 22.3 31.0 Selling, general, and administrative 634.2 758.8 1,267.2 1,447.8 Cost of goods sold 275.6 257.8 541.1 498.2 Cost of collaboration and contract manufacturing 254.6 222.4 453.4 415.8 Other operating expense (income), net — 14.6 — 29.9 2,596.1 2,477.5 5,033.1 4,871.1 Income from operations 1,079.5 1,069.6 1,671.2 1,821.0 Other income (expense): Other income (expense), net 442.8 573.3 764.8 538.7 Interest expense (3.6 ) (14.8 ) (12.3 ) (30.9 ) 439.2 558.5 752.5 507.8 Income before income taxes 1,518.7 1,628.1 2,423.7 2,328.8 Income tax expense 127.1 195.8 223.4 174.5 Net income $ 1,391.6 $ 1,432.3 $ 2,200.3 $ 2,154.3 Net income per share - basic $ 13.24 $ 13.25 $ 20.78 $ 19.95 Net income per share - diluted $ 12.81 $ 12.41 $ 20.02 $ 18.68 Weighted average shares outstanding - basic 105.1 108.1 105.9 108.0 Weighted average shares outstanding - diluted 108.6 115.4 109.9 115.3 TABLE 3 REGENERON PHARMACEUTICALS, OF GAAP TO NON-GAAP FINANCIAL INFORMATION (Unaudited) Three Months Ended June 30, Six Months Ended June 30, 2025 2024 2025 2024 GAAP R&D $ 1,421.7 $ 1,200.0 $ 2,749.1 $ 2,448.4 Stock-based compensation expense 139.0 122.4 280.0 245.4 Acquisition and integration costs — 5.3 — 9.1 Non-GAAP R&D $ 1,282.7 $ 1,072.3 $ 2,469.1 $ 2,193.9 GAAP SG&A $ 634.2 $ 758.8 $ 1,267.2 $ 1,447.8 Stock-based compensation expense 91.8 82.6 187.0 168.8 Acquisition and integration costs — 9.7 0.8 28.5 Non-GAAP SG&A $ 542.4 $ 666.5 $ 1,079.4 $ 1,250.5 GAAP COGS $ 275.6 $ 257.8 $ 541.1 $ 498.2 Stock-based compensation expense 20.9 18.2 40.4 39.1 Acquisition and integration costs — 0.8 — 1.2 Intangible asset amortization expense 32.4 25.1 61.1 48.3 Non-GAAP COGS $ 222.3 $ 213.7 $ 439.6 $ 409.6 GAAP other operating expense (income), net $ — $ 14.6 $ — $ 29.9 Change in fair value of contingent consideration — 14.6 — 29.9 Non-GAAP other operating expense (income), net $ — $ — $ — $ — GAAP other income (expense), net $ 439.2 $ 558.5 $ 752.5 $ 507.8 Gains on investments, net (250.0 ) (392.6 ) (389.9 ) (196.5 ) Non-GAAP other income (expense), net $ 189.2 $ 165.9 $ 362.6 $ 311.3 GAAP net income $ 1,391.6 $ 1,432.3 $ 2,200.3 $ 2,154.3 Total of GAAP to non-GAAP reconciling items above 34.1 (113.9 ) 179.4 373.8 Income tax effect of GAAP to non-GAAP reconciling items (2.1 ) 32.8 (27.7 ) (61.0 ) Non-GAAP net income $ 1,423.6 $ 1,351.2 $ 2,352.0 $ 2,467.1 Non-GAAP net income per share - basic $ 13.55 $ 12.50 $ 22.21 $ 22.84 Non-GAAP net income per share - diluted $ 12.89 $ 11.56 $ 21.06 $ 21.09 Shares used in calculating: Non-GAAP net income per share - basic 105.1 108.1 105.9 108.0 Non-GAAP net income per share - diluted 110.4 116.9 111.7 117.0 RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL INFORMATION (Unaudited) Three Months Ended June 30, Six Months Ended June 30, 2025 2024 2025 2024 Effective tax rate reconciliation: GAAP ETR 8.4 % 12.0 % 9.2 % 7.5 % Income tax effect of GAAP to non-GAAP reconciling items (0.1 %) (1.2 %) 0.4 % 1.2 % Non-GAAP ETR 8.3 % 10.8 % 9.6 % 8.7 % Gross margin on net product sales reconciliation: GAAP gross margin on net product sales 83 % 87 % 82 % 86 % Intangible asset amortization expense 2 % 1 % 2 % 2 % Stock-based compensation expense 1 % 1 % 2 % 1 % Non-GAAP gross margin on net product sales 86 % 89 % 86 % 89 % Six Months Ended June 30, 2025 2024 Free cash flow reconciliation: Net cash provided by operating activities $ 2,189.5 $ 1,866.5 Capital expenditures (448.3 ) (314.4 ) Free cash flow $ 1,741.2 $ 1,552.1 TABLE 4 REGENERON PHARMACEUTICALS, REVENUE (Unaudited) Three Months Ended June 30, Six Months Ended June 30, 2025 2024 2025 2024 Sanofi collaboration revenue: Regeneron's share of profits in connection with commercialization of antibodies $ 1,282.1 $ 988.3 $ 2,300.2 $ 1,792.3 Reimbursement for manufacturing of commercial supplies 161.5 157.3 326.6 263.1 Total Sanofi collaboration revenue 1,443.6 1,145.6 2,626.8 2,055.4 Bayer collaboration revenue: Regeneron's share of profits in connection with commercialization of EYLEA 8 mg and EYLEA outside the United States 383.4 353.0 700.7 686.9 Reimbursement for manufacturing of commercial supplies 31.6 22.1 58.2 44.2 Total Bayer collaboration revenue 415.0 375.1 758.9 731.1 Other collaboration revenue 2.1 3.3 6.2 4.3 Total collaboration revenue $ 1,860.7 $ 1,524.0 $ 3,391.9 $ 2,790.8 TABLE 5 REGENERON PHARMACEUTICALS, PRODUCT SALES OF REGENERON-DISCOVERED PRODUCTS (Unaudited) Three Months Ended June 30, 2025 2024 % Change U.S. ROW Total U.S. ROW Total (Total Sales) EYLEA HD(a) $ 393.2 $ 241.7 $ 634.9 $ 304.2 $ 59.1 $ 363.3 75 % EYLEA(a) $ 754.3 $ 736.0 $ 1,490.3 $ 1,230.5 $ 848.7 $ 2,079.2 (28 %) Total EYLEA HD and EYLEA $ 1,147.5 $ 977.7 $ 2,125.2 $ 1,534.7 $ 907.8 $ 2,442.5 (13 %) Dupixent(b) $ 3,205.0 $ 1,139.6 $ 4,344.6 $ 2,610.2 $ 946.2 $ 3,556.4 22 % Libtayo(c) $ 247.8 $ 128.7 $ 376.5 $ 182.4 $ 115.0 $ 297.4 27 % Praluent(d) $ 65.8 $ 156.2 $ 222.0 $ 56.1 $ 135.8 $ 191.9 16 % Kevzara(b) $ 95.7 $ 56.5 $ 152.2 $ 65.1 $ 44.6 $ 109.7 39 % Other products(e) $ 42.1 $ 30.0 $ 72.1 $ 30.9 $ 21.9 $ 52.8 37 % Six Months Ended June 30, 2025 2024 % Change U.S. ROW Total U.S. ROW Total (Total Sales) EYLEA HD(a) $ 700.0 $ 388.1 $ 1,088.1 $ 504.2 $ 74.3 $ 578.5 88 % EYLEA(a) $ 1,490.3 $ 1,447.4 $ 2,937.7 $ 2,432.1 $ 1,682.9 $ 4,115.0 (29 %) Total EYLEA HD and EYLEA $ 2,190.3 $ 1,835.5 $ 4,025.8 $ 2,936.3 $ 1,757.2 $ 4,693.5 (14 %) Dupixent(b) $ 5,834.4 $ 2,175.8 $ 8,010.2 $ 4,828.2 $ 1,805.0 $ 6,633.2 21 % Libtayo(c) $ 440.3 $ 221.3 $ 661.6 $ 341.6 $ 219.7 $ 561.3 18 % Praluent(d) $ 122.6 $ 292.7 $ 415.3 $ 126.1 $ 267.1 $ 393.2 6 % Kevzara(b) $ 168.5 $ 100.1 $ 268.6 $ 115.1 $ 88.7 $ 203.8 32 % Other products(e) $ 73.2 $ 53.5 $ 126.7 $ 56.2 $ 40.8 $ 97.0 31 % Note: The table above includes net product sales of Regeneron-discovered products. Such net product sales are recorded by the Company or others, as further described in the footnotes below. (a) The Company records net product sales of EYLEA HD and EYLEA in the United States, and Bayer records net product sales outside the United States. The Company records its share of profits in connection with sales outside the United States within Collaboration revenue. (b) Sanofi records global net product sales of Dupixent and Kevzara, and the Company records its share of profits in connection with global sales of such products within Collaboration revenue (c) The Company records global net product sales of Libtayo and pays Sanofi a royalty on such sales (d) The Company records net product sales of Praluent in the United States. Sanofi records net product sales of Praluent outside the United States and pays the Company a royalty on such sales, which is recorded within Other revenue. (e) Included in this line item are products which are sold by the Company and others. Refer to "Second Quarter 2025 Financial Results" section above for a complete listing of net product sales recorded by the Company. Not included in this line item are net product sales of ARCALYST®, which are recorded by Kiniksa.
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