Medscape Poll: Exercise Prescriptions
In this brief survey, Medscape would like to hear about your approach to prescribing exercise to patients.
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
22 minutes ago
- Yahoo
Yoga in a Zimbabwe tavern is the latest mental health outreach in a struggling country
CHITUNGWIZA, Zimbabwe (AP) — It's before sunrise on a Saturday and a small group has gathered at Socialite Bar in on the outskirts of Zimbabwe's capital. Instead of nursing hangovers, they sit with eyes closed and bodies in meditative poses on the bare floor. It's an unlikely setting for a yoga class. In Zimbabwe, the practice is rare and mostly found in the wealthy suburbs. Yet it is quietly taking root here in a beer tavern in Chitungwiza, a low-income town 30 kilometers (18 miles) outside the capital, Harare. The initiative is led by Actions Winya, a yoga instructor who saw how economic hardship and social pressures were damaging the mental health of people in his hometown. 'Yoga is expensive … but we also got humans in the ghetto. They need mental wellness,' said Winya, who usually teaches in affluent areas, charging between $30 and $100 a month. That's an impossible cost for most, especially in a country where many survive through informal jobs. Since 2023, Winya has been offering free weekend classes to some of those hardest hit by Zimbabwe's economic problems. The sessions have become a source of relief for people navigating relentless challenges. Authorities acknowledge a growing societal crisis worsened by drug abuse, domestic violence and poverty, compounded by a shortage of public health services and therapists. 'I am a coach, so they bring the stuff that they face within families (to me). This is where we come in and say, 'Guys, come and try yoga, it can help somehow,'' Winya said. Yoga, an ancient Indian practice, has become a multibillion-dollar industry and a daily ritual for millions around the world. The United Nations over a decade ago designated June 21 as International Day of Yoga. In Africa, other countries like Kenya and South Africa are introducing yoga to poorer communities, with the Indian government promoting its spread across the continent. Inside the tavern in Zimbabwe, mellow music played as about a dozen participants moved through poses. They had no mats, just a cold brick floor, but plenty of determination for inner peace. One mother tried to stay focused as her toddler dashed around, disrupting her poses. For 47-year-old John Mahwaya, the practice has been transforming. A father of four, he also supports relatives in the countryside, a responsibility he said once weighed heavily on his mental health. 'My head was always spinning. I thought I was losing my mind, and the stress started causing back pains,' he said. 'Yoga helps me relax and clear my mind. I sleep peacefully these days.' He said many Zimbabwean men bottle up their emotions, afraid to show weakness in a highly patriarchal society that prizes toughness. 'We focus on physical fitness, forgetting the mind,' he said. 'We suffer slowly, but what suffers first is the mind, and from there, it becomes a slow death.' Edinah Makosa, 24, joined the class earlier this year and said it gave her hope. 'I used to be depressed a lot. You know, for people my age, our main stressors are unemployment and relationships,' she said. 'Yoga changed my mindset. I used to think negatively all the time. Now I have started selling beauty products to earn a living. As for romance, well if it works, it works; if it doesn't, it doesn't. I no longer stress about men. I go with the flow.' As they practiced, the sounds of township life seeped in. Taxi drivers shouted for passengers. Vendors pushed carts, calling out to potential customers. 'We need a proper environment and studio. But we are trying,' Winya said. For participants like Mahwaya, the location didn't matter nearly as much as the healing. 'We need to promote yoga in the communities because everyone has a mind. And fitness of the mind is the responsibility of everyone, regardless of where you live,' he said. ___ For more on Africa and development: The Associated Press receives financial support for global health and development coverage in Africa from the Gates Foundation. The AP is solely responsible for all content. Find AP's standards for working with philanthropies, a list of supporters and funded coverage areas at
Associated Press
30 minutes ago
- Associated Press
Yoga in a Zimbabwe tavern is the latest mental health outreach in a struggling country
CHITUNGWIZA, Zimbabwe (AP) — It's before sunrise on a Saturday and a small group has gathered at Socialite Bar in on the outskirts of Zimbabwe's capital. Instead of nursing hangovers, they sit with eyes closed and bodies in meditative poses on the bare floor. It's an unlikely setting for a yoga class. In Zimbabwe, the practice is rare and mostly found in the wealthy suburbs. Yet it is quietly taking root here in a beer tavern in Chitungwiza, a low-income town 30 kilometers (18 miles) outside the capital, Harare. The initiative is led by Actions Winya, a yoga instructor who saw how economic hardship and social pressures were damaging the mental health of people in his hometown. 'Yoga is expensive … but we also got humans in the ghetto. They need mental wellness,' said Winya, who usually teaches in affluent areas, charging between $30 and $100 a month. That's an impossible cost for most, especially in a country where many survive through informal jobs. Since 2023, Winya has been offering free weekend classes to some of those hardest hit by Zimbabwe's economic problems. The sessions have become a source of relief for people navigating relentless challenges. Authorities acknowledge a growing societal crisis worsened by drug abuse, domestic violence and poverty, compounded by a shortage of public health services and therapists. 'I am a coach, so they bring the stuff that they face within families (to me). This is where we come in and say, 'Guys, come and try yoga, it can help somehow,'' Winya said. Yoga, an ancient Indian practice, has become a multibillion-dollar industry and a daily ritual for millions around the world. The United Nations over a decade ago designated June 21 as International Day of Yoga. In Africa, other countries like Kenya and South Africa are introducing yoga to poorer communities, with the Indian government promoting its spread across the continent. Inside the tavern in Zimbabwe, mellow music played as about a dozen participants moved through poses. They had no mats, just a cold brick floor, but plenty of determination for inner peace. One mother tried to stay focused as her toddler dashed around, disrupting her poses. For 47-year-old John Mahwaya, the practice has been transforming. A father of four, he also supports relatives in the countryside, a responsibility he said once weighed heavily on his mental health. 'My head was always spinning. I thought I was losing my mind, and the stress started causing back pains,' he said. 'Yoga helps me relax and clear my mind. I sleep peacefully these days.' He said many Zimbabwean men bottle up their emotions, afraid to show weakness in a highly patriarchal society that prizes toughness. 'We focus on physical fitness, forgetting the mind,' he said. 'We suffer slowly, but what suffers first is the mind, and from there, it becomes a slow death.' Edinah Makosa, 24, joined the class earlier this year and said it gave her hope. 'I used to be depressed a lot. You know, for people my age, our main stressors are unemployment and relationships,' she said. 'Yoga changed my mindset. I used to think negatively all the time. Now I have started selling beauty products to earn a living. As for romance, well if it works, it works; if it doesn't, it doesn't. I no longer stress about men. I go with the flow.' As they practiced, the sounds of township life seeped in. Taxi drivers shouted for passengers. Vendors pushed carts, calling out to potential customers. 'We need a proper environment and studio. But we are trying,' Winya said. For participants like Mahwaya, the location didn't matter nearly as much as the healing. 'We need to promote yoga in the communities because everyone has a mind. And fitness of the mind is the responsibility of everyone, regardless of where you live,' he said. ___ For more on Africa and development: The Associated Press receives financial support for global health and development coverage in Africa from the Gates Foundation. The AP is solely responsible for all content. Find AP's standards for working with philanthropies, a list of supporters and funded coverage areas at
Yahoo
37 minutes ago
- Yahoo
Structure Therapeutics Announces Two Late-Breaking Poster Presentations at the American Diabetes Association 85th Scientific Sessions Including New Preclinical Data for Oral Small Molecule Amylin Agonist, ACCG-2671
SAN FRANCISCO, June 20, 2025 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic diseases, today announced two upcoming late-breaking poster presentations at the American Diabetes Association 85th Scientific Sessions, being held from June 20-23 in Chicago, IL. 'The amylin receptor is rapidly gaining clinical validation as a key target in obesity, driven by encouraging data from injectable peptide programs. We believe ACCG-2671 is well-positioned and differentiated as an oral small molecule frontrunner that is expected to enter clinical development by the end of 2025,' said Raymond Stevens, Ph.D., Founder and CEO of Structure Therapeutics. 'The preclinical data being presented at ADA include the robust weight-loss effects of ACCG-2671 alone and in combination with a GLP-1 receptor agonist underscoring ACCG-2671's potential as a future small molecule backbone treatment for obesity. In addition, we will present data demonstrating the neuroprotective effects of GLP-1 receptor agonism in preclinical models of Parkinson's disease, reinforcing the broad role of the GLP-1 receptor across different diseases.' Presentation Details: Title: Novel Oral Small Molecule ACCG-2671: A Dual Amylin and Calcitonin Receptor Agonist Development Candidate for Obesity TherapyPoster #: 2184-LBSession: Late Breaking Poster SessionDate: Sunday, June 22Time: 12:30 p.m. – 1:30 p.m. CT Summary: ACCG-2671 demonstrated high binding affinity and balanced potency in human calcitonin receptor (CTR) and amylin receptor (AMY3R) functional assays. In diet-induced obese rats, oral administration of ACCG-2671 resulted in significant, dose-dependent body weight reductions. Combination therapy with semaglutide (both as add-on and concurrent treatment) resulted in superior weight loss compared to monotherapy. Title: Oral Small Molecule GLP-1 Receptor Agonist Demonstrates Beneficial Effects in Parkinson's Disease–Like Model Using Humanized GLP-1R MicePoster #: 1985-LBSession: Late Breaking Poster SessionDate: Sunday, June 22Time: 12:30 p.m. – 1:30 p.m. CT Summary: In a Parkinson's disease mouse model, oral administration of GSBR-5595, a small molecule GLP-1 receptor agonist distinct from Structure Therapeutics' clinical asset aleniglipron (GSBR-1290), significantly improved motor coordination and movement in both the rotarod and open field tests. Additionally, histopathological analyses revealed a significant increase in dopaminergic neurons. These findings suggest this GLP-1 receptor agonist showed neuroprotective effects by mitigating motor deficits and preserving dopaminergic neurons, highlighting a potential benefit in Parkinson's disease. About Structure TherapeuticsStructure Therapeutics is a science-driven clinical-stage biopharmaceutical company focused on discovering and developing innovative oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Utilizing its next generation structure-based drug discovery platform, the Company has established a robust GPCR-targeted pipeline, featuring multiple wholly-owned proprietary clinical-stage oral small molecule compounds designed to surpass the scalability limitations of traditional biologic and peptide therapies and be accessible to more patients around the world. For additional information, please visit Forward Looking StatementsThis press release contains 'forward-looking statements' within the meaning of the 'safe harbor' provisions of the Private Securities Litigation Reform Act of 1995. All statements other than statements of historical fact are statements that could be deemed forward-looking statements, including, without limitation, statements concerning: the Company's future plans and prospects; the belief that ACCG-2671 is well-positioned and differentiated as an oral small molecule frontrunner; the planned initiation of the ACCG-2671 Phase 1 study and the timing thereof; the belief that the oral small molecule approach gives Structure Therapeutics the opportunity to create more scalable, cost-effective treatments to meet the needs of patients with obesity and other related diseases, without compromising on efficacy or safety; the belief that Structure Therapeutics is well-positioned with one of the most robust oral small molecule metabolic franchises in the industry; and any expectations regarding the safety, efficacy or tolerability of ACCG-2671and other candidates under development. In addition, when or if used in this press release, the words and phrases 'anticipated,' 'expect,' 'on track,' 'plan,' 'potential,' 'to be,' and similar expressions and their variants, as they relate to the Company may identify forward-looking statements. Forward-looking statements are neither historical facts nor assurances of future performance. Although the Company believes the expectations reflected in such forward-looking statements are reasonable, the Company can give no assurance that such expectations will prove to be correct. Readers are cautioned that actual results, levels of activity, safety, performance or events and circumstances could differ materially from those expressed or implied in the Company's forward-looking statements due to a variety of risks and uncertainties, which include, without limitation, risks and uncertainties related to the results from earlier clinical studies not necessarily being predictive of future results, potential delays in the commencement, enrollment and completion of the Company's planned clinical studies, the Company's ability to advance ACCG-2671 and its other therapeutic candidates, obtain regulatory approval of and ultimately commercialize the Company's therapeutic candidates, competitive products or approaches limiting the commercial value of the Company's product candidates, the timing and results of preclinical and clinical studies, the Company's ability to fund development activities and achieve development goals, the Company's reliance on third parties, including clinical research organizations, manufacturers, suppliers and collaborators, over which it may not always have full control, the impact of any global pandemics, inflation, tariffs, changes in monetary and fiscal policy, supply chain issues, rising interest rates, future bank failures and other macroeconomic factors on the Company's business, its ability to protect its intellectual property and other risks and uncertainties described in the Company's filings with the Securities and Exchange Commission (SEC), including the Company's latest Annual Report on Form 10-K and Quarterly Report on Form 10-Q and future reports the Company may file with the SEC from time to time. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. The Company undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law. Investors:Danielle KeatleyStructure Therapeutics Media:Dan Budwick1ABDan@ in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
