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Tobacco exposure killed more than 7m people in 2023, study finds

Tobacco exposure killed more than 7m people in 2023, study finds

The Guardian10 hours ago

Exposure to tobacco killed more than 7 million people worldwide in 2023, according to estimates.
It remains the leading risk factor for deaths in men, among whom there were 5.59m deaths, and ranks seventh for women, among whom there were 1.77m deaths.
While the UK has seen a 45% decline in deaths attributed to tobacco since 1990 – including smoking, chewing tobacco and secondhand smoke – the global rate has risen by 24.4%.
The analysis, from the Institute for Health Metrics and Evaluation (IHME) at the University of Washington, is based on data from the Global Burden of Disease study and was presented at the World Conference on Tobacco Control in Dublin on Monday.
Some countries have experienced dramatic rises, the researchers said, with the highest jump in Egypt, where deaths in 2023 were 124.3% higher than in 1990.
Brooks Morgan, a researcher at the IHME, said: 'Tobacco exposure is one of the most significant risk factors identified in the Global Burden of Disease study 2023, contributing to approximately one in eight deaths worldwide.
'While some countries are seeing encouraging declines in tobacco-related deaths, others are heading in the opposite direction. These trends highlight the urgent need for accelerated implementation and stronger enforcement of strategies proven to reduce tobacco use.'
In separate research, a team from the Institute of Clinical and Health Effectiveness (IECS) in Argentina looked at the impact of tobacco use in Bolivia, Honduras, Nigeria, Paraguay and Uruguay.
They calculated tobacco had caused more than 41,000 deaths in the five low- and middle-income countries, and cost nearly $4.3bn (£3.4bn) in medical expenses, lost productivity and informal caregiving.
Natalia Espínola, a coordinator of health economics at the IECS, said the total was equivalent to about 1% of the countries' combined GDP.
Cassandra Kelly-Cirino, the executive director of the International Union Against Tuberculosis and Lung Disease, said: 'The research showcased today at the World Conference on Tobacco Control is a powerful reminder that tobacco remains one of the most devastating public health threats of our time. There is no such thing as a healthy tobacco product, and reduced risk all too often just means increased profit for industry. We must take a zero-tolerance approach.'
A report published by the World Health Organization on Monday urged countries to go further in efforts to tackle tobacco and newer nicotine products such as vapes, including by raising taxes and requiring graphic warnings on packaging.
Dr Tedros Adhanom Ghebreyesus, the WHO director general, told the conference that progress in tobacco control was fragile. He said: 'Despite the rise in regulation, the tobacco industry continues to evolve, pushing new products, targeting youth, and working to erode our gains.'
Higher taxes on tobacco could 'be used for the gaps' in health funding caused by drops in overseas aid in many countries, he suggested.
In another study presented at the conference, researchers from Fudan University in China showed that an AI mobile phone tool designed to help smokers quit using tailored messages and games could double their chances of success.
In a trial involving 272 smokers, 17.6% of those using the tool quit, against 7.4% of those in a control group.

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Ovarian cancer: Widower warns of 'sneaky' symptoms
Ovarian cancer: Widower warns of 'sneaky' symptoms

BBC News

time31 minutes ago

  • BBC News

Ovarian cancer: Widower warns of 'sneaky' symptoms

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Autoimmune disease may almost double risk of mental ill health, study suggests
Autoimmune disease may almost double risk of mental ill health, study suggests

The Guardian

timean hour ago

  • The Guardian

Autoimmune disease may almost double risk of mental ill health, study suggests

Living with an autoimmune disease may almost double the risk of mental health conditions including depression, anxiety and bipolar disorder, a study suggests. The link may be explained by the chronic exposure to systemic inflammation that the autoimmune disease causes, researchers at the University of Edinburgh said. A growing body of evidence suggests that inflammation is linked to mental ill health, but many of the published studies have relied on small sample sizes, limiting their statistical power. To overcome this, researchers drew on data from 1.5 million people in the Our Future Health programme from across the UK. Participants completed a questionnaire that asked for personal, social, demographic, health and lifestyle information. Health information included lifetime diagnoses for disorders including autoimmune and psychiatric conditions. Six autoimmune conditions were included in the study: rheumatoid arthritis, Graves' syndrome (thyroid hormone disorder), inflammatory bowel disease, lupus, multiple sclerosis and psoriasis. The mental health conditions the researchers were interested in were self-reported diagnoses of affective disorders, defined as depression, bipolar or anxiety disorder. In total, 37,808 people reported autoimmune conditions and 1,525,347 did not. The lifetime prevalence of any diagnosed affective disorder was significantly higher among those with an autoimmune disorder than it was among the general population: 29% against 18%. Similar associations emerged for depression and anxiety: 25.5% compared with just over 15% for depression, and just over 21% compared with 12.5% for anxiety. The prevalence of current depression and anxiety was also higher among people with autoimmune conditions. While the prevalence of bipolar disorder was much lower, it was still significantly higher among those with autoimmune disorders than among the general population: just under 1% compared with 0.5%. The prevalence of affective disorders was also significantly and consistently higher among women with autoimmune disorders than it was among men with the same physical health conditions: 32% compared with 21%. The reasons for this are unclear. But the researchers, whose findings were published in the BMJ Mental Health journal, said theories suggest that sex hormones, chromosomal factors, and differences in circulating antibodies may partly explain the differences. Overall, the risk for mental health conditions was nearly double in people with autoimmune conditions – between 87% and 97% higher. It remained high even after adjusting for potentially influential factors, including age, household income and parental psychiatric history. The study was limited by a lack of available information on the time or duration of illness, making it impossible to determine whether autoimmune conditions preceded, co-occurred with or followed affective disorders. No direct measurements of inflammation were made either, making it impossible to establish the presence, nature, timing or severity of inflammation. The researchers concluded: 'Although the observational design of this study does not allow for direct inference of causal mechanisms, this analysis of a large national dataset suggests that chronic exposure to systemic inflammation may be linked to a greater risk for affective disorder. 'Future studies should seek to determine whether putative biological, psychological, and social factors – for example, chronic pain, fatigue, sleep or circadian disruptions and social isolation – may represent potentially modifiable mechanisms linking autoimmune conditions and affective disorders.' They added that it could be worth regularly screening people diagnosed with autoimmune diseases for mental health conditions, especially women, to provide them with tailored support early on.

Are you allergic to summer?
Are you allergic to summer?

Times

time2 hours ago

  • Times

Are you allergic to summer?

You know how it is — you wait all year for some decent weather and then two heatwaves come along in quick succession. Worse, when the sun is out in full force you remember that it's not always as pleasurable as you'd imagined it would be. 'We see a lot of rashes, reactions and heat-related illness at this time of year,' says Dr Dan Baumgardt, a GP and senior lecturer in the school of physiology, pharmacology and neuroscience at the University of Bristol. 'Some of these are related to seasonal temperature changes and some are due to changes in exposure to products, fabrics and chemicals that are more common in the warmer months.' The impact of hot weather can prove fatal, and the UK Health and Security Agency (UKHSA) recently warned people to keep tabs on the colour-coded warnings it jointly issues with the Met Office. For the coming weekend, these have tilted back into red for the southeast of the country, with temperatures expected to surpass 30C. And while red and amber alerts signify the greatest heat risk, yellow weather warnings, the lowest alert threshold, can also be significant. According to the UKHSA many of the 1,311 heat-associated deaths last summer occurred during yellow heat health alert periods and more deaths occurred during heat episodes early in the summer season. But what else do we need to be aware of during the summer months? Here our experts give advice on some of the common — and more unlikely — seasonal ailments. The result of getting so hot that the brain's thermostat fails, this leads to dangerous overheating. It is an emergency and requires urgent medical intervention. 'People don't take the risks of heatstroke seriously enough yet it can have potentially very serious outcomes,' Baumgardt says. Symptoms According to the NHS, symptoms of heat exhaustion include having hot, flushed and dry skin, a headache, nausea, dizziness and confusion. A body temperature over 40C, a change in skin colour, changes in heart or breathing rate, being very thirsty and displaying rapidly worsening responsiveness are clear warning signs. How to treat and avoid it 'It is important to stay hydrated and to avoid excessive alcohol intakes,' Baumgardt says. 'Simple steps such as wearing appropriate clothing and avoiding exercise or hours in the garden at the hottest times of the day are also important.' If someone is displaying signs of heat exhaustion and can be cooled down within 30 minutes — by removing clothing, rehydration with a sports drink or cool water and cooling their skin with cold packs — the NHS says they may not require medical attention. 'But if they don't improve after cooling attempts, call 999 as soon as possible,' Baumgardt says. 'People can develop seizures and risk death if they are not treated immediately.' Rashes and stings are a common hazard but gardeners, hikers and fruit pickers are at risk of more serious skin reactions that occur as a result of phytophotodermatitis, sometimes called 'margarita burn'. Dr Zainab Laftah, a consultant dermatologist at HCA The Shard Hospital in London, says this occurs when skin comes into contact with light-sensitising botanical agents called furanocoumarins that are present in some plants and sap, which then interact with ultraviolet A (UVA) light. Giant hogweed (Heracleum mantegazzianum) is a prime example but other plants can cause similar reactions. 'Handling citrus fruits, celery, parsley, figs and wild parsnip can trigger this in some people,' Laftah says. Wild carrot (Daucus carota) and common hogweed (Heracleum sphondylium) can also be problematic. • My hack for a family hiking holiday? Take the ski lifts in the Swiss Alps Symptoms 'Affected areas become acutely red and nasty blisters or linear streaks appear within 1-2 days of exposure,' Baumgardt says. 'It can take several weeks for the area to heal and might leave permanent pigmentation damage.' How to avoid and treat them 'Wearing gloves and protective clothing while gardening, washing skin thoroughly after plant contact, and avoiding sun exposure immediately after handling potentially reactive plants will help reduce the risk,' Laftah says. Applying sunscreen can help to reduce the light exposure, which might lessen the severity of a reaction. Take care when strimming hedgerows and borders as you can inadvertently come into contact with plant sap. Applying a cold compress to the affected area is recommended. 'You may need topical anaesthetics to avoid infection, so speak to a GP or pharmacist,' Baumgardt says. 'There are a lot of nasty things lurking in rivers, lakes and ponds,' Baumgardt says. 'We get an upswing in ear infections and rashes when people swim outdoors at this time of year.' One specific parasite you might encounter is the larvae of avian schistosome cercariae, which often take up residence in water snails. 'These parasites can burrow into your skin and cause swimmer's itch, or cercarial dermatitis, a nasty allergic reaction to the parasite,' Bamugardt says. Several recreational lakes in the UK have had to close in recent years due to the presence of the parasite and researchers from Liverpool School of Tropical Medicine and Budapest Semmelweis University, reporting in Parasites and Vectors journal, warned that with the increase in popularity of outdoor swimming, the prevalence of swimmer's itch is probably under-reported in the UK. • Help, I've got swimmer's itch! Symptoms An itchy rash and skin redness appears within 24 hours. Nasty red bumps then begin to erupt and that can last for several days. How to treat and avoid it 'Be aware that exposed flesh when swimming in open water does carry risks, so cover up as much as possible and always wear a wetsuit,' Baumgardt says. 'With swimmer's itch, infected skin usually heals in a week without serious complications, although if secondary bacterial infection occurs you will need antibiotics, so see a GP.' A fragrance-free emollient (moisturiser) or anti-itch cream can be helpful when itching is at its worst. Removing the protective layer of socks means that feet come into direct contact with a range of unfamiliar materials and fabrics in footwear, which can cause reactions that result in bumps and rashes. Among the most common footwear allergens, according to researchers at George Washington University, are dyes, leather, rubber, metals and adhesives in shoes. Heat, friction and sweat, along with foot deodorants and sprays, can also increase the risk of contact dermatitis on the feet and between the toes in some people. 'Allergens can trigger allergic shoe contact dermatitis, especially when heat and moisture break down the skin barrier,' Laftah says. 'Wearing well-ventilated shoes made of natural material, avoiding prolonged use of plastic or rubber-based shoes, and using moisture-absorbing socks is recommended.' Symptoms Exposure can cause chronic or acute swelling, blisters or cracks in the skin, a burning sensation, itchiness or pain. How to treat and avoid it 'Contact dermatitis clears up if you remove the materials or substances causing the problem,' Baumgardt says. 'Emollients or moisturisers from a pharmacy might help to ease the condition while the rash is present.' If the symptoms persist and you cannot detect the cause, see a podiatrist or GP for a prescription of topical corticosteroid cream. 'Patch testing can also help identify specific allergens and provide guidance on appropriate shoe wear,' Laftah says. Sunscreen reactions are mostly a reaction to specific chemical ingredients in a product. 'Among the most common irritants are chemical UV filters such as oxybenzone, avobenzone, octocrylene and PABA (para-aminobenzoic acid),' Laftah says. 'These reactions can present as allergic contact dermatitis or photoallergic dermatitis, where UV light activates an allergic response to a compound in the sunscreen.' • Our kids got into a pickle with suncream. So we invented a solution Symptoms Irritant contact dermatitis is more common in people with underlying skin conditions such as eczema. It causes redness and a mild stinging sensation at the site of application. It can sometimes take 24 hours to appear. An itchy, blistering rash where you apply the sunscreen could indicate an allergy to one of the chemicals in the product. Photoallergic dermatitis usually appears on the face, arms, back of hands, chest and lower neck, and may resemble eczema or sunburn. How to treat and avoid it 'Switching to mineral-based sunscreens containing zinc oxide or titanium dioxide, which are less likely to cause irritation or reactions, is a good idea,' Laftah says. 'Avoid fragrances and preservatives in sunscreens which may also contribute to these reactions.' Reactions can be more severe if sunscreen is used with some medications or other topical creams and lotions, so check what you are using. Margaret Kelman, head of clinical services for Allergy UK, says that some people develop rashes on exposure to sand at the beach. 'It can be down to the fact that sand is drying and abrasive or a combo of sand and seawater and a reaction to sunlight,' she says. General debris and insects in the sand can also cause problems. 'Abroad there are parasites and creatures such as sand flies can lead to bites and rashes,' Baumgardt says. Symptoms Skin can become inflamed, sore and itchy. How to treat and avoid it 'Apply moisturiser as well as SPF to provide an extra barrier and wash or shower as soon as you get back home,' Kelman says. 'Sit on a beach towel and wear longer or more protective beach clothes.' If skin flares up, over-the-counter topical steroids might be needed. Chlorine is added to pools as a disinfectant to keep them clean and safe for swimming. In itself, chlorine is not an allergen but it can have a drying effect on the skin, potentially exacerbating dermatitis and eczema. 'Chlorine can also irritate the lungs in people with asthma,' Kelman says. 'Eyes can be irritated by the chemicals.' • 24 of the best baby and child-friendly hotels in the UK Symptoms Itchy red skin or hives (itchy bumps), difficulty breathing and sore, red eyes are all signs of chlorine irritation. How to treat and avoid it 'If your skin is affected, put on moisturiser in addition to sunscreen before getting in the pool, shower as soon as you get out and then reapply,' Kelman says. 'Wear goggles to protect your eyes from the chlorine and use your inhaler when needed if you have asthma and are spending more time in or near swimming pools.' Pollen-induced hay fever affects as many as 13 million people in the UK — the majority of whom are allergic to grass pollens in the summer months. Symptoms Sneezing, coughing, a runny or blocked nose, as well as red, itchy or watery eyes. How to treat/avoid it 'Speak to a GP, who will help to create a treatment plan,' Kelman says. Options include antihistamines such as fexofenadine, nasal steroid sprays such as Nasonex (both available on prescription) and sodium cromoglicate eye drops (such as Opticrom). Nasal saline washes such as the NeilMed Sinus Rinse Kit (£21.99, are also worth trying. 'They can be useful to help rinse allergens that may be present in the nasal passages,' Kelman says. Government weather health alerts: Allergy UK:

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