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India Nears Completion of Phase III Dengue Vaccine Trials

India Nears Completion of Phase III Dengue Vaccine Trials

Hans India6 days ago
New Delhi/Hyderabad: The Ministry of Health and Family Welfare has confirmed significant progress in the Phase III trial of India's first dengue vaccine, 'DengiAll.' This clinical study, conducted by the Indian Council of Medical Research (ICMR), aims to evaluate the efficacy of a live attenuated tetravalent vaccine against all four known serotypes of the dengue virus.
This update was provided in response to a question raised by Eatala Rajender, a Member of Parliament, during a Lok Sabha session on Friday. The multi-centre trial has enrolled over 10,000 participants, with more than 70% of the enrollment completed. The study is being conducted at 20 designated research centres across India, including key sites such as JSS Medical College and Hospital in Mysore (Karnataka), Bangalore Medical College & Research Institute in Bengaluru (Karnataka), and AIIMS Bibinagar in Hyderabad (Telangana). Each site has been allocated a budget of approximately Rs 1.3 to Rs 1.5 crore.
Dengue remains a major public health challenge in India. Data from the Integrated Health Information Platform (IHIP) indicates that there were 573,563 laboratory-confirmed dengue cases reported in 2024, ranking the country among the top 30 worldwide for disease prevalence.Currently, there is no licensed antiviral treatment or vaccine available for dengue in India. The treatment protocol is supportive, following national clinical management guidelines developed by the Union Health Ministry. These guidelines have been shared with all states and Union Territories to enhance preparedness and response capabilities during outbreaks.
Given the circulation of all four dengue virus serotypes (DENV-1 to DENV-4) across different regions of India—sometimes even within the same individual—the ICMR has strategically selected trial zones that reflect this viral diversity. This method aims to assess the vaccine's broad-spectrum efficacy.
In parallel, the government is implementing efforts under the National Health Mission (NHM), which include vector control measures, fogging operations, public awareness campaigns, and improved surveillance infrastructure. Sentinel Surveillance Hospitals and Apex Laboratories have been established to facilitate free diagnosis and reporting.
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Embark On A Celestial Odyssey
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Inquiry panel wants FIR lodged against then Nashik Civil Hospital officials & firm for cheating govt
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  • Time of India

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Why 650 Haryana hospitals have halted AB-PMJAY services, in move set to hit 1.4 crore beneficiaries
Why 650 Haryana hospitals have halted AB-PMJAY services, in move set to hit 1.4 crore beneficiaries

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time3 hours ago

  • The Print

Why 650 Haryana hospitals have halted AB-PMJAY services, in move set to hit 1.4 crore beneficiaries

The Centre's flagship health insurance scheme, AB-PMJAY, provides Rs 5 lakh annual coverage per family for secondary and tertiary hospitalisation, benefitting over 12 crore economically vulnerable families across India. Of them, 1.364 crore beneficiaries are from Haryana. The Indian Medical Association, Haryana, has declared a complete halt in the implementation of the scheme in private hospitals over pending dues estimated at Rs 500 crore. According to IMA, Haryana, nearly 650 private hospitals have not received reimbursements this quarter, and some dues have been pending for over a year now. New Delhi: Haryana private hospitals empanelled under the Ayushman Bharat–Pradhan Mantri Jan Arogya Yojana (AB-PMJAY) have suspended services under the healthcare scheme, citing non-payment of reimbursements by the state government. On 6 August, at an emergency meeting with Haryana's chief secretary and senior health officials, the IMA learnt that Haryana had released Rs 145 crore and the Centre Rs 70 crore for the scheme implementation in the current quarter. Even with Rs 245 crore paid by the two governments—an IMA statement said—dues of Rs 490 crore are still pending. 'The root of the problem is the budgetary mismatch,' said Dr Suresh Arora, a senior consultant at Surya Ortho & Trauma Centre in Faridabad, which is among the private hospitals suspending services under AB-PMJAY. 'Haryana's annual budget for the scheme is nearly Rs 700 crore, but actual expenses exceed Rs 1,400–1,500 crore. This shortfall has persisted for the last three years.' His hospital alone has pending dues of Rs 20 lakh. ThePrint has learnt that another large, multi- or super-speciality hospital, the 2,600-bed Amrita Hospital, which Prime Minister Narendra Modi inaugurated in Faridabad on 24 August 2022, is yet to be reimbursed Rs 18 crore under the scheme. A total of 32,736 hospitals are empanelled under AB-PMJAY across India, including 15,024 private and 17,712 government hospitals. Haryana currently has 1,341 empanelled hospitals, according to official data. 'This has become a pattern every three months,' said Dr Dhirendar K. Soni, the secretary of IMA Haryana. 'Payments delayed, hospitals threaten to suspend services, and then a part of the money is released.' Also Read: Chhattisgarh pvt hospitals are gaming Ayushman Bharat PMJAY. It's the state with 2nd highest frauds 'Interest clause not honoured' Hospitals also allege that the Haryana government has failed to honour a key clause in the Memorandum of Understanding (MoU)—paying interest on delayed payments. The original MoU included a clause for interest payment in the case of delayed payments under the PM-JAY scheme, but states like Haryana reportedly have removed it. 'Not only is that not paid, but we are also seeing deductions in reimbursements,' said Dr Arora. 'They are rejecting cases on flimsy grounds, not offering additional payments to NABH-accredited hospitals—those certified for maintaining higher standards of care and patient safety—and in some cases, reimbursing only Rs 4,000–5,000 on bills worth Rs 18,000.' An IMA delegation, which previously met Chief Minister Nayab Singh Saini in February to raise these concerns, 'was assured of a resolution, but nothing has happened since', Dr Soni said. Dr Girdhar J. Gyani, Director-General of the Association of Healthcare Providers of India (AHPI), which represents over 15,000 private hospitals, including major chains such as Fortis, Max, Manipal, Medanta, and Apollo, pointed out two structural issues with the scheme. 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